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      • 아스팔트 콘크리트의 고온변형저항 특성 측정방법 개발

        김광우,이문섭,김중렬,이순제 강원대학교 부설 석재복합신소재 제품연구센터 2002 석재연 논문집 Vol.7 No.-

        본 연구는 정하중하에서 아스팔트 혼합물의 소성변형 저항특성을 측정할 수 있는 새로운 시험방법을 개발하기 위하여 수행되었다. 2가지 골재(편마암, 화강암)와 6가지 아스팔트(일반아스팔트, 5가지 개질 아스팔트)를 사용하여 총 12개의 밀입도 혼합물을 제작하였다. 마샬 배합설계를 통해 최적아스팔트 함량을 구하고, 결정된 최적아스팔트 함량으로 마샬공시체(S=10 cm)와 자이레토리 공시체(S=15cm)를 제작하여 마샬안정도시험, 휠 트랙킹 시험, 개발된 김테스트(Kim -test)를 수행하였다. 김테스트는 공시체와 하중봉을 지지할 수 있는 김시험장치(Kim tester)를 이용하여 하단이 반경(r) 0.5 또는 1.0cm로 원형절삭한 직경(D) 3cm, 4cm의 하중봉을 사용한다. 또한 재하는 마샬 하중재하 장치를 사용하여 공시체를 60℃ 수조에 30분동안 수침시킨 후 실시되었다. 정하중은 공시체의 직경방향이 아닌 축 방향으로 50 mm/min가 가해졌고, 최대하중(P_max)과 수직변형(y)이 측정되었다. 마샬안정도시험과 간접인장강도시험에서 얻어지는 것과 유사한 곡선이 각각의 시험에서 얻어졌다. 강도값은 P_max, r, y 및 H(=D-2r)을 이용한 K_D=4P_max/π(H+2√(2ry-y^2))^2식을 통하여 계산하였고, 이를 변형강도(kgf/㎠)로 정의하였다. 실험결과, 공시체 직경이나 골재종류보다는 하중봉과 하중봉 하단의 원형처리 여부가 K_D와 P_max 값에 영향을 미치는 것으로 나타났다. 통계분석결과에서 K_D가 소성변형 깊이와 동적 안정도에 높은 상관성을 보였다. 향후 연구를 통해 K_D의 유효성이 검증된다면, Kim-test는 아스팔트 혼합물의 소성변형 저항성을 판단할 수 있는 시험방법으로 사용될 수 있을 것이다. This study dealt with developing a new approach for finding properties which might represent rut resistance characteristics of asphalt mixture under static loading. Two aggregates, a normal asphalt (pen 60-70) and 5 PMAs were used in preparation of 12 dense-grade mixtures. Marshall mix design was used in determination of the optimum asphalt content (OAC) and each mixture at the OAC was prepared for a newly-developed Kim test on Marshall specimen (S=10 cm) and gyratory specimen (S=15cm), and for wheel tracking test. Kim test used Marshall loading frame and the specimen was conditioned for 30min at 60℃ before loading through Kim tester, and apparatus consisting of a loading column and a specimen and column holder. Diameter (D) of column was 3cm and 4cm with each column having different radius (r) of round cut at the bottom. The static load was applied at 50mm/min in axial direction of the specimen, not in diameteral direction, and the maximum load (P_max) and vertical deformation (y) at the maximum load point were measured. A curve, similar to the one from a Marshall test or static indirect tensile strength test was obtained from each test. A strength value was calculated based on the P_max, H(=D-2r). r and y by using the equation K_D=4P_max/π(H+2√(2ry-y^2))^2 and is defined as deformation strength (kgf/㎠). The values of P_max/y and K_I=K-D/y were also calculated to see if these have any correlation with rutting. In general, D and r were significant factors affecting K_D, while specimen size was not. The statistical analyses results showed the K_D had the best correlation with rut depth and dynamic stability. The next best correlation was found from P_max which was followed by P_max/y and K_I in order. Therefore, K_D can be used for selecting the highly resistable asphalt mixture against permanent deformation.

      • KCI등재

        야뇨증 환아들의 심리사회적 특성에 대한 다기관 연구 : 행동 및 정서 문제를 중심으로

        조수철,김재원,신민섭,황준원,한상원,박관현,이상돈,김경도,김건석,서홍진,이유식,정재용,김영균,문두건,남궁미경,한창희,조원열,김영식,배기수,이종국,정우영,신의진 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.6

        Objectives : The aim of this study was to examine the behavioral and emotional problems associated with nocturnal enuresis in Korean children. Methods : Three hundred eighteen children with nocturnal enuresis, together with their parents, completed the Child Behavior Checklist (CBCL), Disruptive Behavior Disorder Scale according to DSM-IV (DBDS), Children's Depression Inventory (CDI), State-Trait Anxiety Inventory for Children (STAIC), and Piers-Harris Children's Self-Concept Scale (PHCSC). Ninety-three normal students were selected as the control group. Results : Compared to the normal control group, the mean scores with regard to the withdrawn, social problems, attention problems, delinquent behavior, aggressive behavior, externalizing problems and total problems profiles were significantly higher in the nocturnal enuresis group according to the CBCL results. The nocturnal enuresis group also scored significantly higher in the ADHD and ODD profiles of the DBDS. The nocturnal enuresis group was more depressed and anxious than the control group according to the results of the CDI and STAI. The mean score of the PHCSC was significantly lower in the nocturnal enuresis group when compared to the normal control group. Conclusion : The results of this study suggest that children with nocturnal enuresis in Korea have clinically relevant behavioral and emotional problems. The findings support the link between nocturnal enuresis and psychopathology in Korean children.

      • 흰쥐 뇌세서의 Cholecystokinin mRNA 함유신경세포의 분포

        김우태,배명애,이호섭,박매자,배용철,홍해숙,조희중,주강 慶北大學校 醫科大學 1994 慶北醫大誌 Vol.35 No.4

        목적 : 뇌에서 Cholecystokinin(CCK)-8 함유신경세포의 분포에 대해서는 면역조직화학적기법을 이용하여 행한 연구가 많으나 CCK mRNA함유신경세포의 분포에 대한 연구는 아직 단편적이므로 본 연구에서는 이들 신경세포의 분포를 정확히 밝히고져 하였다. 대상 및 방법 : 흰쥐 뇌에서 ^35S가 표지된 oligonucleotide를 이용한 in situ hybridization기법으로 관찰하였다. 결과 및 결론 : 종뇌; 후구의 전후핵, 신피질, 이상엽, 후내야, 외측, 기저 및 피질 편도핵, 해마체, 그리고 선조체에서 CCK mRNA함유신경세포가 관찰되었다. 간뇌; CCK mRNA함유신경세포가 시상의 경우 전내측시상핵, 전복측시상핵, 외측시상핵, 내측시상핵, nucleus reunions, nucleus rhomboideus, 그리고 내측슬상핵에서 관찰되었으며 시상하부의 경우는 시삭상핵, 실방핵, 등내측시상하부핵, 그리고 유두상핵에서 관찰되었다. 중뇌; 흑질의 밀집부, 복측피개야, nucleus linea rostralis, 중심회색질, Edinger-Westphal nucleus, 그리고 하구에서 CCK mRNA 함유신경세포가 관찰되었다. 교 및 연수; CCK mRNA 함유신경세포들이 lateral parabrachial nucleus 삼차신경척수로고유핵, 거대그물구성체핵, 연수그물구성체, 그리고 삼차신경척수로핵에서 관찰되었다. 이상의 결과를 지금까 보고된 CCK-8함유신경세포의 분포에 대한 면역조직화학적 연구결과와 비교 하였을 때 대부분의 부위에서 CCK-8 및 CCK mRNA 함유신경세포의 분포가 유사하였으나 시상의 경우 CCK-8 함유신경세포는 검출되지 않은 반면 매우 많은 수의 CCK mRNA 함유신경세포가 존재함을 알 수 있었고 대뇌 피질의 경우 CCK mRNA 함유신경세포수가 CCK-8 함유신경세포보다 월등히 더 많았다. 반면, 등측봉선핵 및 고속핵에서는 CCK-8 함유신경세포가 다수 존재함이 보고되어 있으나 본 연구의 경우 CCK mRNA 함유신경세포를 관찰할 수 없었다. In order to investigate the distribution of cholecystokinin(CCK) mRNA containing neurons in the rat brain, brains were extirpated rapidly, frozen sectioned and processed for in situ hybridization technique with ^35S labeled oligonucleotide probe. The results obtained were as follows Telencephalon; CCK mRNA containing neurons were found in the anterior olfactory nucleus, neo-cortex, piriform cortex, entsorhinal cortex, lateral, basal and cortical amygdaloid nucleus, hippocampus and corpus striatum. Diencephalon; In the anterior medial thalamic nucleus, anterior ventral thalamic nucleus, lateral thalamic nucleus, medial thalamic nucleus, nucleus reuniens, nucleus rhomboideus, and medial geniculate nucleus, CCK mRNA containing neurons were found. In the hypothalamus, CCK mRNA containing neurons were located in the supraoptic nucleus, paraventricular nucleus, dorsomedial nucleus and supramammillary nucleus. Midbrain; CCK mRNA containing neurons were found in the substantia nigra pars compacta, ventral tegmental area, nucleus linea rostralis, substantia gricea centralis, Edinger-Westphal nucleus and inferior colliculus. Pons and Medulla oblongata; CCK mRNA containing neurons were found in the lateral parabrachial nucleus, nueteus originalis nervi trigemini, nucleus reticularis gigantocellularis, nucleus reticularis medullae oblongatae, nucleus tractus spinalis nervi trigemini.

      • 소양호에서 인의 존개 형태별 분포에 관하여 : The Distribution of Phosphorus Fractions in Lake Soyang

        김범철,허우명,황길순,김동섭,최광순 江原大學校 附設 環境硏究所 1996 環境硏究 Vol.13 No.-

        The distribution of phosphorus in Lake Soyang from January 1985 to August 1992 was surveyed by the measurement of soluble reactive phosphorus(SRP), total dissolved phosphorus(DTP), and total phosphorus(TP) concentration. SRP concentration was in the range of 2~7㎎/㎥ in epilimnion, and 4~200㎎P/㎥ in hypolimnion. The vertical distribution pattern of SRP showed a large difference with the season. SRP concentration decereased during the growing season of phytoplankton in the epilimnion of Lake Soyang and increased in hypolimnion during the oxygen depletion. Higher concentration near the bottom implies they are diffused from the bottom sediment where organic particles are settled and degraded. SRP, DOP, POP and TP concentration was higher in the meralimnion of Lake Soyang in rainy season It might be related with storm runoff. General trend of TP variation is that the TP concentration of water column is increasing substantially from yeat to year. TP concentration in the surface water increased from 5㎎P/㎥ at 1985 to 20㎎P/㎥ at 1992.

      • 소양호 부영양학의 연변화 추이

        김범철,조규송,허우명,김동섭 江原大學校 附設 環境硏究所 1989 環境硏究 Vol.6 No.-

        The trend of trophic status change in Lake Soyang from 1981 to 1989 was studied by the measurement of chlorophyll a concentration, transparaency, total phosphorus concentration, and the rate of hypolimnetic oxygen deficit rate. And the phosphorus loading from the watershed was measured monthly at the main inflowing river, Soyan River. The increasing trend of chlorophyll was clear at the rate of 0.4 /£㎍/l/yr. The advent and expansion of Anabaena bloom was the major cause of chlorophyll, increase and transparency reduction. The rate of hypolimnetic oxygen deficit also increased from 0.032 mg Ο_(2)/cm^(2)/day in 1986 to 0066 in 1988. The trophic state of Lake Soyang can be assessed as oligotrophy before 1983, mesotrophy from 1984 to 1988, and eutrophy since 1989. Phosphorus loading from floating net fishfarms was estimated to be larger than 45% of total. The phosphorus loading from only watershed is smaller than the dangerous critical loading, but, if the fishfarms loading added, it exceeds the critical loading.

      • KCI등재후보

        Interleukin-2를 이용한 진행성 위장관암의 비장을 경유한 자가 LAK Cell의 면역학적 반응

        안우섭,강중신,김인호,전석길,손수상 啓明大學校 醫科大學 1993 계명의대학술지 Vol.12 No.3

        To elucidate the anticancer effect by observing the effect of LAK cells after infusion of IL-2 through splenic artery for the advanced gastrointestinal cancer, randomized study was performed for the 8 patients who had liver metastasis from gastic and rectal cancer. 4 patients were performed subtotal gastrectomy for stomach cancer and the others were done abdominoperineal resections for rectal cancer. The liver metastasis were noted all of the cases after surgery between October 1989 and December 1992 at the Department of Surgery, Keimyung University School of Medicine. After confirmation of the hepatic metastasis from gastorintestinal cancer, we performed selective splenic arterial infusin of IL-2 with the dosage of 20,000 units/kg B.W. We checked the immune function pre-and post-IL2 infusion therapy, such as total lymphocyte count, T-cell percentage and CMI multitest with blood count and hepatorenal function. There was no difference between the pre-and post IL-2 infusion in the hemoglobin, serum protein, albumin, BUN and creatinin. The total lymphocyte counts of pre-and post IL-2 infusion were 1641.2 and 1727.4, respectively. The T cell percentage of pre-and infusion were 62.51% and 64.27%, respectively and had the tendency to increase in comparison with pre-IL-2 infusion, but there were not stastical differences. The results of CML muiltitest of pre-and post IL-2 infusion were not definite differences. From the above results, it could be suggested that LAK cell after infusion of IL-2 via selective splenc artery had the slightly positive effect of the immune function of advanced gastrointestinal cancer patient, with hepatic metastasis.

      • 都市産業의 特性과 經濟基盤分析에 관한 硏究

        심태섭,정영동,김우혁 朝鮮大學校 建設技術硏究所 1999 建設技術硏究 Vol.19 No.1

        Recently, small and medium sized cities are to be a new limelight in developing countries. Because, they have performed important roles in promoting are spreading economic and social development of the country. I can assert that it is the optimum time to smooth out difference between regions, to activate local small and medium cities at this time. Because the recognition against polarization reversal on the dispersal policies than the first stage of the powerful trend of concentrative development. This study is concerned with all small and medium sized cities in Kore.a, and has two main purpose. First one is to select the general analysis variables affecting urban growth from existing theoretical literatures, Second one is to identify the dominant factor and their change for the growth of small and medium sized cities in Korea through the analysis of correlation with growth rate. The basic goal of this treatise puts on emphasize to issue the problems through looking into realities and functional roles of small and medium cities in the urban system for the past 10 years in Korea, to find out alternative method in order to activate the strengthening of foundation and functional activity of local small and medium cities by analyzing the relevancy between functional character and growth potentiality of individual cities.

      • SCOPUSSCIEKCI등재

        파킨슨씨병 환자에 있어서 자가부신수질 이식술

        정상섭,박상근,오성훈,김선호,윤도흠,박정수,양우익,최인준,안영수,김경환,박창일,김진수,이현철 대한신경외과학회 1988 Journal of Korean neurosurgical society Vol.17 No.6

        Recent experimental studies and clinical cases have suggested that grafting tissue from the adrenal medulla into the brain may alleviate the symptoms of Parkinson's disease. Autologous adrenal medullary grafts into the striatum was performed stereotactically in two patients with Parkinson's disease. Both patients were bedridden preoperatively, but 4 months after the surgery both became ambulatory and one was even capable of returning to his job. Even though the number of cases was small⑵ and the follow-up period was short, this study shows that adrenal medullary transplantation into the striatum may have some beneficial effects in patient with Parkinson's disease. Further experimental and clinical trials are necessary to see whether this procedure will be a recommendable surgical treatment for patients suffering from Parkinson's disease.

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