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Different polyamine levels in the vertex and occipital hair of pattern hair loss patients
( Ki-hun Kim ),( Bong Chul Chung ),( Yu Ra Lee ),( Jeongae Lee ),( Jong Ki Hong ),( Bark Lynn Lew ),( Woo Young Sim ) 대한피부과학회 2019 대한피부과학회 학술발표대회집 Vol.71 No.2
Background: Pattern hair loss generally begins from the vertex or front of the head. Androgenic steroids, particularly testosterone and dihydrotestosterone are related with pattern hair loss. They existed differently in the vertex and occipital region of scalp and involved in inducing ornithine decarboxylase (ODC) expression. ODC is central enzyme in polyamine biosynthesis. The polyamine produced by ODC plays an important role in pattern hair loss by presenting at different levels along the scalp area. Objectives: This study was conducted to evaluate pathogenesis and diagnosis of patients with pattern hair loss by identifying the differences in polyamine levels according to the area of scalp. Methods: For the profiling of polyamines in patients with pattern hair loss, a liquid chromatography-mass spectrometrybased quantitative profiling method was used. We investigated the differences in polyamine levels in different regions of the hair between patients with male-pattern hair loss and those with female pattern hair loss. Results: We found almost polyamine levels were higher in vertex than occipital hair. Also we confirmed difference levels between N-acetyl polyamines and polyamines in same area of hair. Our results suggest that proliferation occurs at the vertex region rather than at the occipital region. Conclusion: High concentration of polyamine in vertex hair may relate with pattern baldness which begins at vertex.
나프탈렌과 다우섬 히트파이프의 작동 특성에 관한 실험적 연구
박기호(Ki-Ho Park),이영수(Young-Soo Lee),나호상(Ho-Sang Ra),장기창(Ki-Chang Chang) 대한기계학회 2006 대한기계학회 춘추학술대회 Vol.2006 No.6
This paper is concerned with the heat transfer characteristics, the long-term operating of medium temperature range on the heat pipe. Working fluids used in the tests are Naphthalene, Dowtherm A. As a result, Dowtherm A as the working fluid have been proper at 200℃ to 300℃ temperature range, Naphthalene have been proper at 300℃ to 430℃temperature range. The heat pipe tested is made of SUS 316L tube of 27.2 ㎜ in outside diameter, 2.1 ㎜ in thickness and 700 ㎜ in length. Working fluid of about 40% of the inside volume of evaporator section of heat pipe is filled. In the case of the Naphthalene heat pipe, the heat transfer coefficient is 1520 W/㎡K , the heat transfer rate is 1300 W. In Dowtherm heat pipe the heat transfer rate is 1000 W.
김기원 ( Ki Won Kim ),정혜경 ( Hye Kyoung Chung ),이한민 ( Han Min Lee ),조아라 ( A Ra Cho ),이세환 ( Se Whan Lee ),나성수 ( Seong Su Nah ),모상일 ( Sang Il Mo ),이혁규 ( Hyeok Gyu Lee ),고규봉 ( Gyu Bong Ko ),강병일 ( Byong Il Ka 대한류마티스학회 2011 대한류마티스학회지 Vol.18 No.1
Klinefelter`s syndrome (KFS) is a gonosomal aberration disease that occurs in males, and is characterized by 47, XXY karyotype, hypogonadism and a lack of secondary sexual characteristics. A potential link between this hormonally deficient syndrome and autoimmune disease, particularly systemic lupus erythematosus (SLE), has been reported. On the other hand, KFS is rarely reported to be accompanied by rheumatoid arthritis (RA), and there are no Korean cases reported. We report the first Korean case of a KFS patient with sero-positive RA and discuss the role of the pathogenesis of RA with KFS.