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증례 : 호흡기 ; 골수형성이상증후군에서 폐 침윤과 흉수를 동반한 스위트 증후군 1예
고규봉 ( Gyu Bong Ko ),이혁규 ( Hyeok Gyu Lee ),이호성 ( Ho Sung Lee ),최재성 ( Jae Sung Choi ),서기현 ( Ki Hyun Seo ),나주옥 ( Ju Ock Na ),김용훈 ( Yong Hoon Kim ) 대한내과학회 2011 대한내과학회지 Vol.80 No.2
저자들은 75세 골수형성이상증후군 환자에서 폐 침윤과 동반된 양측 흉수가 발생한 스위트 증후군 1예를 경험하였기에 이를 보고한다. Sweet`s syndrome is characterized by a constellation of clinical symptoms, physical features, and pathologic findings, which include fever, leukocytosis, tender erythematous skin lesions, and a diffuse infiltrate consisting predominantly of mature neutrophils in the upper dermis. Pulmonary involvement in Sweet`s syndrome is rare. In addition, a pleural effusion has been rarely reported in the pulmonary involvement of Sweet`s syndrome. We report a case of Sweet`s syndrome presenting with pulmonary involvement and a bilateral pleural effusion in a patient with myelodysplastic syndrome. (Korean J Med 2011;80:216-220)
김기원 ( Ki Won Kim ),정혜경 ( Hye Kyoung Chung ),이한민 ( Han Min Lee ),조아라 ( A Ra Cho ),이세환 ( Se Whan Lee ),나성수 ( Seong Su Nah ),모상일 ( Sang Il Mo ),이혁규 ( Hyeok Gyu Lee ),고규봉 ( Gyu Bong Ko ),강병일 ( Byong Il Ka 대한류마티스학회 2011 대한류마티스학회지 Vol.18 No.1
Klinefelter`s syndrome (KFS) is a gonosomal aberration disease that occurs in males, and is characterized by 47, XXY karyotype, hypogonadism and a lack of secondary sexual characteristics. A potential link between this hormonally deficient syndrome and autoimmune disease, particularly systemic lupus erythematosus (SLE), has been reported. On the other hand, KFS is rarely reported to be accompanied by rheumatoid arthritis (RA), and there are no Korean cases reported. We report the first Korean case of a KFS patient with sero-positive RA and discuss the role of the pathogenesis of RA with KFS.