단무지 공장에서 발생한 질식 사고의 원인과 방사선학적 소견: 중례보고 및 가스분석 결과

박충기,김만구,김흥철,안범규,박만수,황우철,최철순,강익원 江原大學校 附設 環境硏究所 1994 環境硏究 Vol.11 No.-

목 적:단무지 공장에서 질식사고를 일으켰던 가스의 종류를 알아내고, 이러한 가스중독의 방서선학적 소견을 소개하기 위하여 본 연구를 하였다. 대상 및 방법:단무지 공장에서 발생한 질식 사고자 3예중 생존자 1예를 대상으로 단순흥부X-선검사와 CT 소견을 분석하였으며, 가스의 종류를 알아내기 위하여 단무지를 유리병에 넣어 발생된 가스를 가스크로마토그래픽을 이용하여 분석하였다. 결 과:단무지 공장에서 발생한 질식사고자중 생존한 1명의 방사선학적 검사에서 신속히 호전되는 폐경결(consolidation)을 볼 수 있었으며 이는 폐부종의 소견임을 알 수 있었다. 협기성 상태에서 단무지를 담은 유리병의 상층부 가스를 실험 분석한 결과 이산화탄소, 에칠알코올이 다량으로 검출되었으나 독성가스는 주로 황화수소이였다. 결 론:단무지 공장의 질식 사고자에서 폐방사선학적 소견은 폐경결을 보이는 폐부증으로서 이는 실험을 통해 단무지에서 발생되는 유독가스인 황화수소 때문임을 입증하였다. Purpose: To identify the main toxic gas released from salted radish in rice bran(Dan-M-Ji) and to introduce the radiological findings of the patient who was exposed to the gas. Materials and Methods: Chest radiographs and CT scans of one survivor among three men who were exposed to the gas from Dan-Mu-Ji were reviewed. Gas obtained from the closed bottle containing Dan-Mu-Ji was analized by using the gas chromatography. Results: The radiographlc examinations of the survivor were suggestive of pulmonary edema with it's rapidly improving consolidations in both lung. The headapace gas within the bottle containing Dan-Mu-Ji was mainly composed with carbon dioxide, ethyl alcohol and hydrogen sulfide, of which hydrogen sulfide was considered the main toxic gas released. Conclusion: Under the anaerobic condition, Dan-Mu-Ji released toxic hydrogen sulfide. Inhalation of hydrogen sulfide might produce non-cardiogenic pulmonary edema.

동안신경 상분지만을 침범한 토로사-헌트 증후군 1예

성기범,이태경,박선아,안무영 대한평형의학회 2003 Research in Vestibular Science Vol.2 No.2

뇌 자기공명영상상 뇌량 병변의 호전을 보인 Marchiafava-Bignami병 1예

정재훈,성기범,안무영,신현길,박형국 대한신경과학회 1999 대한신경과학회지 Vol.17 No.5

업무 관련성 견갑상 포착 신경증이 의심되는 3례

정두신,성기범,신현길,안무영,김형수,홍영의 大韓産業醫學會 1999 대한직업환경의학회지 Vol.11 No.4

Objectives : Entrapment of the suprascapular nerve is frequently overlooked in the differential diagnosis of shoulder pain. Methods : Suprascapular entrapment neuropathy is a well-defined clinical entity and EMG and NCV is used to confirm a diagnosis. But the diagnosis typically not considered until patients develop severe weakness secondary to atrophy of the spinous musculature that the nerve supplies. Results : A narrow suprascapular notch has rarely been reported as a work-related factor of this entrapment neuropathy. Diagnosis of suprascapular entrapment neuropathy is based on the patients' clinical course, neurologic, radiologic, and electrophysiologic findings. One of the most helpful evaluations was anteriorposterior projection with the X-ray tube angled 15-30 degree caudally. The suprascapular entrapment neuropathy is relatively uncommon entity of shoulder discomfort(pain, weakness, and atrophy). Conclusions : If the worker who used his shoulder joint repetitiously having the shoulder pain and muscle weakness, we must rule out the suprascapular entrapment neuropathy. And it is needed to evaluate the motions which cause suprascapular entrapment neuropathy as the ergonomic factor.

고나트륨혈증후 발생한 중심성 뇌교및 외뇌교 수초 용해증 1예

신현길,성기범,오건세,안무영 순천향대학교 1994 논문집 Vol.17 No.2

중심성 뇌교 수초 용해증은 일반적으로 심한 기저질환을 지닌 환자에서 심한 저나트륨혈증이나 저나트륨혈증을 급속 교정후 오는 것으로 알려져 있다. 저자들은 최근 만성 주정중독환자에서 심한 고나트륨혈증을 서서히 교정후 발생한 중심성 뇌교 및 외뇌교 수초 용해증을 뇌 자기공명 전산화 단층촬영으로 확진하였다. 심한 기저 질환을 가진 환자에서 장기간의 고나트륨혈증의 경우도 중심성 뇌교 수초 용해증을 일으킬 수 있기 때문에 이런 환자에서 저나트륨혈증뿐 아니라 고나트륨혈증도 피해야 될 것으로 사료된다.

혐기성 소화에 대한 식종원 및 암모니아 농도의 영향

김양지,김성일,신범식,안기섭,김종수 한국환경농학회 2004 한국환경농학회지 Vol.23 No.1

혐기성 소화에서 미생물에 저해/독성 물질로 알려진 암모니아의 농도와 식종원에 따른 영향 을 회분식 반응기를 이용하여 분석하였다. 식종원은 고농도의 암모니아에 장기간 적응된 축 산농가 축산폐수 집수조의 슬러지 그리고 저농도의 암모니아에 노출된 하수종말처리장 혐기 성 소화조 슬러지를 사용해서 COD 제거율과 biogas 발생량으로 측정된 혐기성 미생물의 활성에 저해영향을 주기 시작하여 3,500 ㎎-N/L에서는 더욱 심하였다. 암모니아 저해 농도 범위에서 휘발성 유기산의 농도는 50㎎/L 범위로 유지되므로 메탄생성균 뿐만 아니라 산생 겅균도 저해영향을 받는 것으로 나타났다. 축산폐수 집수조 슬러지로 식종된 경우 암모니아 농도가 TAN으로 2,500∼3,500 ㎎-N/L 범위에서도 COD 제거율과 biogas 발생량의 감소폭 은 미미하였으나, 하수종말처리장 혐기성 소화조 슬러지로 식종된 경우 암모니아 농도가 증 가할수록 COD 제거율과 biogas 발생량은 큰 폭으로 감소하였다. 결과적으로 암모니아에 장 기간 순응된 슬러지로 식종한 경우 암모니아의 저해 농도에 대하여 적응도 빨랐으며 저해영 양도 적었다. The seeding sources and concentration of ammonia on anaerobic digestion were investigated by batch culture bioreactors. The sourcces of seeding on anaerobic digestion were from swine wastewater collection pit of a hog raising farm and from anaerobic digestion sludge of a municipal sewage treatment plant. The inhibition of ammonia on anaerobic microoganisms was initiated at ammonia concentration of 1,500 ㎎NH₄-N/L and it s effect was increased by increasing ammonia concentration up to 3,500 ㎎NH₄-N/L, regardless the sources of seeding as evidenced by decreases in COD removal efficiencies and biogas yields. The inhibition occurred to not only methanogens but also acidogens since the concentration of volatile fatty acids was maintained at 50 ㎎/L. The COD removal efficiency and biogas yield were maintained constantly while increasing ammonia concentration up to 3,500 ㎎NH₄-N/L when swine wastewater collection pit was used as a seeding; however, those were decreased while increase ammonia concentration when anaerobic digestion sludge was used as a seeding. The results indicate that the seeding acclimated to high concentrations of ammonia for long time was easy in adaptation to high ammonia concentration and less subjective to ammonia inhibitory effects.

이차 전기영동을 이용한 프로테오믹 접근을 통한 정맥 압박이 혈장 프로테옴에 미치는 영향

양광익,박선아,오형근,정두신,박형국,성기범,안무영,홍세용 순천향대학교 2006 Journal of Soonchunhyang Medical Science Vol.12 No.1

The human proteomics-based approaches, which examine the expressed proteins of a tissue or cell type, are increasingly being used. Venous occlusion is commonly employed for stimulating tissue-plasminogen activator (t-PA) and plasminogen activator inhibitor-1 (PAI-l) release from venous endothelial cells, and this has been regarded as a parameter of the individual fibrinolytic capacity of plasma. The present work involved a detailed investigation of the plasma proteome and fibrinolytic activity in normal subjects, with the aim of determining whether correlations exist between various parameters of the fibhnolytic system before and after venous occlusion. We analyzed fibhnolytic parameters and plasma proteome before and after 15-min periods of venous occlusion in the forearm in 10 healthy 3rd-decade volunteers. Proteome analysis was performed using two-dimensional gels. The tryptic digests of some proteins were confirmed by MALDI-TOF and the MS-Fit algorithm. The fibrinolytic response as measured by the absolute amount of t-PA after venous occlusion was increased by venous occlusion (5.5 vs 9.6 ng/㎗, p<0.05), as was PAI-l (46.8 vs 56.1 ng/㎗, p<0.05). However, two-dimensional electrophoresis finding was virtually nonspecific and inconsistent after venous occlusion in healthy male subjects. Venous occlusion does not influence plasma proteome in healthy males. Although the fibhnolytic response to venous occlusion is attributed to an increase in free tUPA antigen, this change is not correlated with plasma proteome.

알코올 금단 발작 환자에서 진전 섬망 예방에 대한 Nimodipine과 Chlordiazepoxide의 효과 비교

정두신,양광익,이보람,방차옥,이태경,성기범,안무영,박형국 순천향의학연구소 2001 Journal of Soonchunhyang Medical Science Vol.7 No.1

Background & objectives : An increase of calcium influx during alcohol withdrawal state may contribute to neuronal hyperexitability, which cause delirium tremens(DT). Some investigators have found calcium channel blockers effects in prevention of DT in experimental animals. Therefore we evaluated the preventive effects of calcium channel blocker(nimodipine) and benzodiazepine(chlordiazepoxide) on the development of DT in alcohol withdrawal seizure(AWS) patients. Method : A total 59 patients with AWS were divided into three groups according to the management nimodipine-treated, chlordiazepoxide-treated, and control(no specific medication) groups. We compared the incidence rates of DT in the three groups. Results : Total incidence rate of DT was 30.5%(18 of 59 patients). There were 6 DTs of 18 patients(33.5%) in nimodipine-treated group, 4 of 21 patients(22.5%) in chlordiazpoxide-treated group, and 8 of 20 patients(44.0%) in control. Conclusion : The control group(44.0%) showed the highest incidence rate of DT. And nimodipine-treated(33.5%) and chlordiazepoxide-treated group(22.5%) were followed. However, this result failed to demonstrated statistically significant differences due to small numbers size.

흉부 위국소화 감각 수준으로 발현된 경부 추간판 탈출증

이보람,조동신,윤신구,조상걸,안무영,성기범 대한신경과학회 1999 대한신경과학회지 Vol.17 No.5

비위도관을 통한 위내영양공급으로 치유된 임신오조증 2 예

안기범(Ki Bum Ahn),왕영미(Young Mee Wang),박종규(Jong Kyou Park),신옥철(Ok Cherl Shin),조정철(Jung Cherl Cho),김진호(Jin Ho Kim),홍선희(Sun Hi Hong),강창성(Chang Seong Kang) 대한산부인과학회 1998 Obstetrics & Gynecology Science Vol.41 No.12

Traditionally, total parenteral nutrition(TPN) has been used when patients with hypaemesis gravidarum failed to respond to conservative management, but now many physicians attempt to enteral feeding via nasogastric tube because TPN is expensive and has many complications. Recently, we experienced 2 cases of hyperemesis gravidarum successfully managed by enteral feeding via nasogastric tube, therefore we think that this method may be carefully considered to the patients with hyperemesis gravidarum failed to respond to conservative management. So we report them with brief review of the literatures.