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Yu, K‐,H.,Hong, K‐,S.,Lee, B‐,C.,Oh, M‐,S.,Cho, Y‐,J.,Koo, J‐,S.,Park, J‐,M.,Bae, H‐,J.,Han, M‐,K.,Ju, Y‐,S.,Kang, D‐,W.,Appelros, P. Blackwell Publishing Ltd 2011 Acta neurologica Scandinavica Vol.123 No.5
<P>Yu K‐H, Hong K‐S, Lee B‐C, Oh M‐S, Cho Y‐J, Koo J‐S, Park J‐M, Bae H‐J, Han M‐K, Ju Y‐S, Kang D‐W, Appelros P, Norrving B, Terent A. Comparison of 90‐day case‐fatality after ischemic stroke between two different stroke outcome registries using propensity score matching analysis. Acta Neurol Scand: 2011: 123: 325–331. © 2010 John Wiley & Sons A/S.</P><P><B>Background – </B> It has not been clarified whether the disparity in ischemic stroke outcome between populations is caused by ethnic and geographic differences or by variations in case mix. Propensity score matching (PSM) analysis can overcome some analytical problems but is rarely used in stroke outcome research. This study was to compare the ischemic stroke case‐fatality between two PSM cohorts of Sweden and Korea.</P><P><B>Methods – </B> Prognostic variables related to baseline characteristics and stroke care were included in our PSM model. Then, we selected 7675 Swedish and 1220 Korean patients with ischemic stroke from each stroke registers and performed one‐to‐one matching based on propensity scores of each patient.</P><P><B>Results – </B> After PSM, all measured variables were well balanced in 1163 matched subjects, and the 90‐day case‐fatality was identical 6.2% (HR 0.997, 95%CI 0.905–1.099) in Sweden and Korea.</P><P><B>Conclusions – </B> No difference is found in the 90‐day case‐fatality in propensity score‐matched Swedish and Korean patients with ischemic stroke.</P>
Kim, E-K,Seo, H-S,Chae, M-J,Jeon, I-S,Song, B-Y,Park, Y-J,Ahn, H M,Yun, C-O,Kang, C-Y Macmillan Publishers Limited 2014 Gene therapy Vol.21 No.1
For successful clinical tumor immunotherapy outcomes, strong immune responses against tumor antigens must be generated. Cell-based vaccines compromise one strategy with which to induce appropriate strong immune responses. Previously, we established a natural killer T-cell (NKT) ligand-loaded, adenoviral vector-transduced B-cell-based anticancer cellular vaccine. To enhance tumor antigen delivery to B cells, we established a modified adenoviral vector (Ad-k35) that encoded a truncated form of the breast cancer antigen Her2/neu (Ad-k35HM) in which fiber structure was substituted with adenovirus serotype 35. We observed increased tumor antigen expression with Ad-k35HM in both human and murine B cells. In addition, an Ad-k35HM-transduced B-cell vaccine elicited strong antigen-specific cellular and humoral immune responses that were further enhanced with the additional loading of soluble NKT ligand KBC009. An Ad-k35HM-transduced, KBC009-loaded B-cell vaccine efficiently suppressed the in vivo growth of established tumors in a mouse model. Moreover, the vaccine elicited human leukocyte antigen (HLA)-A2 epitope-specific cytotoxic T-cell responses in B6.Cg (CB)-Tg (HLA-A/H2-D) 2Enge/Jat mice. These findings indicated that the Ad-k35 could be appropriate for the preclinical and clinical development of B-cell-based anticancer immunotherapies.
Kang, B.Y.,Lee, S.S.,Song, M.S.,Cho, K.K.,Han, S.H.,Cho, B.K. Elsevier 2016 CURRENT APPLIED PHYSICS Vol.16 No.9
<P>Emergence of anomalous weak ferromagnetism in geometrically frustrated magnetic system of R1-xYxB4 (R = Tb and Dy) is quite interesting [Phys. Rev. B 91, 024414 (2015)]. In order to study the weak ferromagnetism in other compounds, the magnetic properties of R1-xYxB4 (R = Sm, Gd, and Er) were investigated. The anomalous weak ferromagnetism was also found to occur in all compounds, R1-xYxB4 (R = Sm, Gd, and Er). The weak ferromagnetism is revealed in the magnetic easy plane, (001), for R1-xYxB4 (R = Sm and Gd) and along the magnetic easy axis, [001], for R1-xYxB4 (R = Er). The magnitude of saturated magnetic moment at T = 2 K shows a strong dependence on Y-concentration, i.e., the maximum magnitude occurs at x approximate to 0.3 for all compounds. The general magnetic properties of weak ferromagnetism is quite similar to the weak ferromagnetism in R1-xYxB4 (R = Tb, Dy). Therefore, it is experimentally demonstrated that the emergence of weak ferromagnetism, induced by non-magnetic substitution in a magnetically frustrated system, is the universal feature in RB4 compounds. (C) 2016 Elsevier B.V. All rights reserved.</P>
C.K. Kang,H.S. Nam,Y.K. Lee,S.B. Lee,B.M. Lee,Y.J. Oh,H.J. Jee,M.K. Hong,K.W. Jung,Y.J. Lee,Y.H. Choi 한국유기농업학회 2011 韓國有機農業學會誌 Vol.19 No.S
Among the developed bío-degradable polymer fílms as compared wíth transparent fílm(Whíte), black polymer fílm was sígnífícantly more effectíve for controllíng weeds ín red pepper. Also, we found that whíte and black polymer mulchíng had 81.8% and 97.9% of managing weed controllíng effects in rice, respectively. Compared to nonmulched rice paddy with water supply, the non-mulched rice paddy wíthout any water supply has stopped its growth at 41 days after transplantíng, whíle polymer -mulched rice paddy without water supply had about 60% of normally growing rice plants. This shows the polymer treatment has a remarkable effect on water and power saving, solution of herbicidal resistance, avoidance of herbícidal influence to eco-system etc. When the naturally decomposíng polymer was used, a temperature was elevated as high as 4.7 ℃ on maximum and 2.6 ℃ on average. Also the naturally decomposing polymer accelerated rooting by 7 days and lowered a stress level from transplanting. The weed control effect mulched by polymer was remarkable as 98. 7%. The p이ymer now, after 294 days treated on the rice paddy, has been completely decomposed.
Roh, J.-H.,Kang, M.,Wei, B.,Yoon, R.-H.,Seo, H.-S.,Bahng, J.-Y.,Kwon, J.-T.,Cha, S.-Y.,Jang, H.-K. Elsevier 2016 Poultry science Vol.95 No.5
<P>The production performance, efficacy, and safety of two types of vaccines for infectious bursal disease virus (IBDV) were compared with in-ovo vaccination of Cobb 500 broiler chickens for gross and microscopic examination of the bursa of Fabricius, bursa/body weight (b/B) ratio, flow cytometry, and serologic response to Newcastle disease virus (NDV) vaccination. One vaccine was a recombinant HVT-IBD vector vaccine (HVT as for herpesvirus of turkeys) and the other was an intermediate plus live IBDV vaccine. A significant difference was detected at 21 d. Eight of 10 chickens that received the IBDV live vaccine had severe bursal lesions and a relatively low b/B ratio of 0.95, and an inhibited NDV vaccine response. On the other hand, the HVT-IBD vector vaccine resulted in mild bursal lesions and a b/B ratio of 1.89. Therefore, the live vaccine had lower safety than that of the HVT-IBD vector vaccine. To determine the protective efficacy, chickens were intraocularly challenged at 24 d. Eight of 10 chickens in the IBDV live vaccination group showed gross and histological lesions characterized by hemorrhage, cyst formation, lymphocytic depletion, and a decreased b/B ratio. In contrast, the HVT-IBD vector vaccinated chickens showed mild gross and histological lesions in three of 10 chickens with a b/B ratio of 1.36, which was similar to that of the unchallenged controls. Vaccinated chickens showed a significant increase in IBDV antibody titers, regardless of the type of vaccine used. In addition, significantly better broiler flock performance was observed with the HVT-IBD vector vaccine compared to that of the live vaccine. Our results revealed that the HVT-IBD vector vaccine could be used as an alternative vaccine to increase efficacy, and to have an improved safety profile compared with the IBDV live vaccine using in-ovo vaccination against the Korean very virulent IBDV in commercial broiler chickens.</P>
단감 '부유' 과실의 저장특성에 미치는 수확기 동상해 및 과수원 온도조건의 영향
곽용범,김승희,안광환,이창훈,강성구,Kwack, Y.B.,Kim, S.H.,Ahn, K.H.,Lee, C.H.,Kang, S.K. 국립한국농수산대학교 교육개발센터 2021 현장농업연구지 = Journal of practical agricultural resear Vol.23 No.1
단감 '부유'의 가을 동상해 발생과 과실생장에 미치는 식재위치의 표고와 농장의 온도환경의 영향과, 서리가 발생한 과수원의 과실 저장 특성을 알아보고자 경남 창원(과원 A)과 창녕(과원 B)의 경사지 과원에서 표고별(상, 중, 하)로 과실특성을 조사하고 서리가 발생한 후 수확한 과실을 MA저장 후 저장특성(품질, 저온장해)을 조사하였다. 수확기 전후(10월25일, 11월5일, 11월20일)에 조사된 두 과원의 과실의 생장 특성(과중, 당도, 경도)은 표고와 농장 요인의 유의미한 영향을 받지 않았다. 과실 착색은 표고 요인의 영향을 받았으며, 과실의 착색(hunter 'a')은 B 과원보다 A 과원에서 더 빨리 진행되었다. 수확기에 발생한 저온으로 인하여 과원 B의 하부에서만 약 2%의 과실에서 동상해 피해가 관찰되었다. 두 과원(A, B)에서 11월 5일과 11월 20일에 수확한 과실을 저밀도 폴리에틸렌 필름을 사용하여 MA저장 한 결과, 저온지 과원(B)보다 고온지 과원(A)의 과실 경도가 높게 유지되었다. 그리고 11월 5일에 수확한 과실은 약 80일 저장 후에도 건전과율이 과원 A에서 약 73%, 과원 B에서 약 85%로 높게 유지되었으나, 11월 20일(서리 발생 후) 수확한 과실은 A 과원의 과실은 약 80일 저장 후에도 76%의 높은 건전과율을 유지하였으나 B 과원의 과실 건전과율은 약 14%에 불과했다. We analyzed the effect of planting site (elevation: high, middle, low) and temperature condition of orchard on the frost injury occurrence and storage characteristics of persimmon (Diospyros kaki cv. 'Fuyu) fruits under an early fall frost at two orchards, Changwon (A) and Changnyeong (B), Gyeongsangnam-do Korea. Also, the fruits picked at Nov. 5 and Nov. 20 were MA stored to investigate the quality and chilling injury of fruits. On 2-way factor analysis, both planting elevation and orchard factor had not a significant effect on fruit characteristics (weight, firmness, soluble solid), while planting elevation factor did on the skin color (hunter 'a')(p<0.05). A fruit skin coloration at orchard A was faster than that at orchard B. At low elevation of orchard B, 2% fruits were frost injured at harvest season. On LDPE film MA storage with the fruits harvested at Nov. 5 and Nov. 20, the fruits at orchard A had higher fruit firmness than those of orchard B during storage. In addition, the 73% (orchard A) and 85%(orchard B) fruits harvested at Nov. 5 showed no chilling injury 80 days after storage. However, At harvest of Nov, 20 (after incidence of frost), only the 14% fruits of orchard B had no the chilling disorder 80 days after storage, even though 76% fruits at orchard A did.
중년 사무직 남성의 직무스트레스와 허리둘레, 체질량지수의 관계에 관한 연구
강수임,고보경,김지영,노정연,리청,송주은,이현영,이혜민,최유경,정덕유,이민경 이화여자대학교 간호과학대학 2016 이화간호학회지 Vol.- No.50
Purpose: The purpose of this study was to determine the relationship between job stress, body mass index and waist circumference among middle aged male workers. Methods: Using a descriptive correlation study design, a total of 122 middle aged male workers were recruited through convenience sampling from November 8 to December 13, 2015. The questionnaire included in this study were general characteristics and the Korean Occupational Stress Scale-Short Form (KOSS-SF). Data were statistically analyzed using SPSS windows version 22 program with Pearson’s correlation coefficient. Results: A significant relationship was found between job stress, body mass index (p=.043) and waist circumference (p=.007). Conclusion: These results suggest that high job stress are significantly associated with both body mass index and waist circumference of middle aged male workers. This implies a need for intervention that focuses on reducing obesity and metabolic syndrome influenced by job stress.