RBF Kernel Based Support Vector Machine with Universal Approximation and Its Application to Battery Model

Junping Wang,Hyungsuck Cho 제어로봇시스템학회 2005 제어로봇시스템학회 국내학술대회 논문집 Vol.2005 No.10

Differential Diagnosis of Axillary Inflammatory and Metastatic Lymph Nodes in Rabbit Models by Using Diffusion-Weighted Imaging: Compared with Conventional Magnetic Resonance Imaging

Junping Wang,Qian Liao,Yunting Zhang,Chunshui Yu,Renju Bai,Haoran Sun 대한영상의학회 2012 Korean Journal of Radiology Vol.13 No.4

Objective: This experiment aims to determine the diagnostic value of diffusion-weighted imaging (DWI) in the differentiation of axillary inflammatory lymph nodes from metastatic lymph nodes in rabbit models in comparison with conventional magnetic resonance imaging (MRI). Materials and Methods: Conventional MRI and DWI were performed at 4 weeks after successful inoculation into the forty female New Zealand white rabbits’ mammary glands. The size-based and signal-intensity-based criteria and the relative apparent diffusion coefficient (rADC) value were compared between the axillary inflammatory lymph nodes and metastatic lymph nodes, with histopathological findings as the reference standard. Receiver operating characteristic (ROC) curve analysis was performed to evaluate the diagnostic performance of the aforementioned criteria and rADC value in differentiating the axillary inflammatory lymph nodes from metastatic lymph nodes. Results: Thirty-two axillary inflammatory lymph nodes and 46 metastatic ones were successfully isolated and taken into pathological analysis. The differences of the aforementioned criteria between the two groups were not statistically significant (p > 0.05). However, the rADC value of the inflammatory lymph nodes (0.9 ± 0.14) was higher than that of metastatic ones (0.7 ± 0.18), with significant difference (p = 0.016). When the rADC value was chosen as 0.80, the area under the ROC curve is greater than all other criteria, and the sensitivity, specificity, accuracy, positive predictive value, and negative predictive value for differentiating two groups were 86.2%, 79.3%, 81.2%, 84.2%, and 85.6%, respectively. Conclusion: Diffusion-weighted imaging is a promising new technique for differentiating axillary inflammatory lymph nodes from metastatic lymph nodes. Compared with routine magnetic resonance sequences, DWI could provide more useful physiological and functional information for diagnosis. Objective: This experiment aims to determine the diagnostic value of diffusion-weighted imaging (DWI) in the differentiation of axillary inflammatory lymph nodes from metastatic lymph nodes in rabbit models in comparison with conventional magnetic resonance imaging (MRI). Materials and Methods: Conventional MRI and DWI were performed at 4 weeks after successful inoculation into the forty female New Zealand white rabbits’ mammary glands. The size-based and signal-intensity-based criteria and the relative apparent diffusion coefficient (rADC) value were compared between the axillary inflammatory lymph nodes and metastatic lymph nodes, with histopathological findings as the reference standard. Receiver operating characteristic (ROC) curve analysis was performed to evaluate the diagnostic performance of the aforementioned criteria and rADC value in differentiating the axillary inflammatory lymph nodes from metastatic lymph nodes. Results: Thirty-two axillary inflammatory lymph nodes and 46 metastatic ones were successfully isolated and taken into pathological analysis. The differences of the aforementioned criteria between the two groups were not statistically significant (p > 0.05). However, the rADC value of the inflammatory lymph nodes (0.9 ± 0.14) was higher than that of metastatic ones (0.7 ± 0.18), with significant difference (p = 0.016). When the rADC value was chosen as 0.80, the area under the ROC curve is greater than all other criteria, and the sensitivity, specificity, accuracy, positive predictive value, and negative predictive value for differentiating two groups were 86.2%, 79.3%, 81.2%, 84.2%, and 85.6%, respectively. Conclusion: Diffusion-weighted imaging is a promising new technique for differentiating axillary inflammatory lymph nodes from metastatic lymph nodes. Compared with routine magnetic resonance sequences, DWI could provide more useful physiological and functional information for diagnosis.

The Explanation of the Cultural Attribute of Terrorism

Junping Wang 아시아경찰학회 2003 아시아경찰학회 국제학술회의 Vol.2003 No.-

Terrorism is a kind of social phenomena that has clear culture attribute. It not only has the political cultural attribute, but also has the cultural character in the crime of terror; however, it is a kind of cultural law phenomenon basically. As a result, only have to place the terrorism in the conformity of political sub-culture, the crime sub-culture and the law sub-culture to discuss, can we hold the immanent stipulation, and bring forward the countermeasures to defending and controlling, even can we set the standard of the normal aptitude for anti-terrorism, making it have the higher political legality to get more positive achievement in anti-terrorist action.

Effect of Sheep and Chicken Antibodies to Rat Adipocytes Plasma Membranes on Rat Carcass Fat

Wang, Jundong,Zhang, Jianfeng,Li, Junping,Hao, Junhu,Wang, Shaolin,Zhang, Jianhai Asian Australasian Association of Animal Productio 2004 Animal Bioscience Vol.17 No.8

Polyclonal anti-sera were collected from sheep and chicken immunized with adipocytes plasma membranes. Thirty two male wistar rats, weighing 185-215 grams, were divided randomly into 4 groups (trial 1: control group and treat group, trial 2: control group and treat group), with 8 rats in each group. The experiment lasted for 7 weeks. Trial one: The control group received four consecutive daily intraperitoneal injections of 1ml of sheep normal sera. The same 4 day daily dose of group sheep anti-rats sera adipocyte plasma membrane anti-sera was administered to the treat group. The results showed that the treatment for treat group increased body weight by 6.35% (p<0.05) and food intake by 6.85%, and improved food conversion efficiency (Food intake/gain) by 45.00% (p<0.05). Periernal, epididymal and omental adipose deposit weights were decreased by 23.92% (p<0.05), 34.45% (p<0.05) and 0.98% respectively, while total fat content decreased by 20.92%. Trial two: The control group received four consecutive daily intraperitoneal injections of 1 ml of chicken normal sera, the results of injections of chicken anti-rats sera adipocyte plasma membrane antis-era administered to the treat group indicated that chicken anti-rats adipocyte plasma membranes immunization had an disadvantageous effect on the growth of the wistar rats by the end of 7th wk, compared with the control group. The immunized group decreased in total weight by 40 gram (p<0.05) an averagely and in food intake noticeably (p<0.01). The deposition of fat and the rates of TG and FFA in serum had no statistical significance.

ELECTROCHEMICAL Co 3 O 4 NANOPOROUS THIN FILMS SENSOR FOR HYDROGEN PEROXIDE DETECTION

GUANG SHENG CAO,RUILIN WANG,PEILONG WANG,XIN LI,YUE WANG,JUNPING LI,GUILONG WANG 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2014 NANO Vol.9 No.4

The nanoporous Co 3 O 4 thin ¯lms were prepared on indium tin oxide (ITO) glasses by anelectrodeposition method. The surface morphology and composition of the nanoporous Co 3 O 4¯lms were characterized by scanning electron microscopy (SEM), energy-dispersive X-rayanalysis (EDS) and X-ray photoelectron spectroscopy (XPS). The results show that the as-deposited nanoporous Co 3 O 4 ¯lm is constructed by many interconnected nano°akes withthickness of about 40 nm. The cyclic voltammetry (CV) measurement indicates that thenanoporous Co 3 O 4 ¯lms exhibit remarkable electrocatalytic activities for the hydrogen peroxide(H 2 O 2 ) reduction which shows that it is a good candidate to be employed as electrode materialsfor electrochemical sensing of H 2 O 2 . Further analysis indicated that the detection sensitivityof the sensor was 1.357 mA mM? 1 cm? 2 and the detection limit was estimated to be about0.2 mM.

Effect of kaolin additive on PM_2.5 reduction during pulverized coal combustion: Importance of sodium and its occurrence in coal

Si, Junping,Liu, Xiaowei,Xu, Minghou,Sheng, Lei,Zhou, Zijian,Wang, Chao,Zhang, Yang,Seo, Yong-Chil Elsevier 2014 APPLIED ENERGY Vol.114 No.-

<P><B>Abstract</B></P> <P>Little work has been performed on the importance of sodium and its occurrence in coal to PM<SUB>2.5</SUB> (particles less than 2.5μm in aerodynamic diameter) reduction by kaolin during O<SUB>2</SUB>/N<SUB>2</SUB> combustion and O<SUB>2</SUB>/CO<SUB>2</SUB> combustion at high temperatures. In this study, the combustion experiment of a treated low-sodium coal with sodium aluminosilicate additive was conducted in a lab-scale drop tube furnace (DTF) at 1500°C to reveal the contribution of mineral melting and coalescence to PM<SUB>2.5</SUB> reduction. Meanwhile, two typical Na-loaded coals (in which the sodium was loaded in the form of NaCl and sodium carboxylate, respectively) with kaolin added were also burnt under O<SUB>2</SUB>/N<SUB>2</SUB> and O<SUB>2</SUB>/CO<SUB>2</SUB> atmospheres to investigate the effect of interaction between kaolin and different chemical form sodium on PM<SUB>2.5</SUB> reduction. The results show that sodium aluminosilicate is able to promote the migration of PM<SUB>0.5–2.5</SUB> (particles in aerodynamic diameter of 0.5–2.5μm) to form coarse particles. Due to the stronger reactivity of sodium carboxylate reacting with kaolin than that of NaCl, PM<SUB>0.2–0.5</SUB> (particles in aerodynamic diameter of 0.2–0.5μm) decreases more significantly in the combustion when adding kaolin into the NaAc-loaded coal than into NaCl-loaded coal. In addition, the PM<SUB>0.2–0.5</SUB> reduction in O<SUB>2</SUB>/CO<SUB>2</SUB> combustion is lower than that in O<SUB>2</SUB>/N<SUB>2</SUB> combustion owing to the less vaporization of metals and the slower diffusion rate of vapors in the O<SUB>2</SUB>/CO<SUB>2</SUB> atmosphere in comparison to those in the O<SUB>2</SUB>/N<SUB>2</SUB> atmosphere. The mineral coalescence varied in interactions of kaolin with NaAc and NaCl. Besides, the PM<SUB>0.5–2.5</SUB> emission differed as a result of differences in coal characteristic and the atmosphere, and this would cause the difference of collision frequency between particles and additive. With the joint actions of mineral coalescence and particle collision, the NaAc-loaded coal has a higher PM<SUB>0.5–2.5</SUB> reduction by kaolin than NaCl-loaded coal, especially under the O<SUB>2</SUB>/N<SUB>2</SUB> combustion. An expression describing the relationship of PM<SUB>0.5–2.5</SUB> reduction, mineral coalescence and particle collision was fitted and it is found that the mineral coalescence has a stronger influence than particle collision on PM<SUB>0.5–2.5</SUB> reduction by kaolin.</P> <P><B>Highlights</B></P> <P> <UL> <LI> The sodium aluminosilicate plays an important role in PM<SUB>2.5</SUB> reduction by kaolin. </LI> <LI> The capability of kaolin to reduce PM<SUB>2.5</SUB> depends on the sodium occurrence in coals. </LI> <LI> The effect of kaolin on PM<SUB>2.5</SUB> reduction becomes weaker during O<SUB>2</SUB>/CO<SUB>2</SUB> combustion. </LI> <LI> Particle collision may be taken into consideration for PM<SUB>2.5</SUB> reduction. </LI> </UL> </P>

Online Adaptive Optimal Tracking Control of Nonholonomic Mobile Robot

Kai Wang,Yingmin Jia,Junping Du,Jun Zhang 제어로봇시스템학회 2012 제어로봇시스템학회 국제학술대회 논문집 Vol.2012 No.10

A velocity control law is developed for the kinematic steering system of nonholonomic mobile robot to track a reference trajectory not only to make the posture error asymptotically stable but also considered optimality based on a pre-defined cost function. In order to make the cost function finite, we transformed the tracking problem into a regulation problem by redefining system states and inputs. The proposed online and forward-in-time policy iteration (PI) algorithm based on approximate dynamic programming (ADP) to solve the continuous-time(CT) optimal control problem with infinite horizon cost by solving of Hamilton-Jacobi-Bellman (HJB) equation. This method learns online in real-time to approximate the cost function by using a single neural networks (NNs), and then the near optimal control policy can be computed directly according to the cost function, which removes the action network appearing in the ordinary ADP methods. Simulation results are provided to demonstrate the effectiveness of the proposed approach.

Antibiotic resistance, biochemical typing, and PFGE typing of Bifidobacterium strains commonly used in probiotic health foods

Feili Xu,Junping Wang,Yunchang Guo,Huawei Zeng,Ping Fu,Zhigang Li,Xiaoyan Pei,Xiumei Liu,Shuo Wang 한국식품과학회 2018 Food Science and Biotechnology Vol.27 No.2

This study firstly analyzed the antibiotic resistance, biochemical typing, and pulsed-field gel electrophoresis typing of 45 Bifidobacterium strains commonly used in health foods. Most strains were resistant to antibiotics but their antibiotic resistance rates were not high: Fos (56.52%), TET (43.48%), CRO (21.74%), AMC (15.22%), GEN (13.04%), RIF (10.87%), CHL (8.7%), CTX (6.52%), VAN (4.35%), and ERY (4.35%). The 45 strains could be divided into 14 pulsed-field gel electrophoresis types, of which the strain numbers of six pulsed-field gel electrophoresis types were more than one. All the Bifidobacterium strains could be divided into nine types by API50CHL biochemical identification. The same species displayed same biochemical typings, expect for B. animalis. Furthermore, the results confirmed that the same pulsed-field gel electrophoresis-type strains had closer antibiotic resistance patterns, and the same biochemicaltype strain also had similar antibiotic resistance patterns.

Antibiotic resistance, biochemical typing, and PFGE typing of Bifidobacterium strains commonly used in probiotic health foods

Xu, Feili,Wang, Junping,Guo, Yunchang,Fu, Ping,Zeng, Huawei,Li, Zhigang,Pei, Xiaoyan,Liu, Xiumei,Wang, Shuo 한국식품과학회 2018 Food Science and Biotechnology Vol.27 No.2

This study firstly analyzed the antibiotic resistance, biochemical typing, and pulsed-field gel electrophoresis typing of 45 Bifidobacterium strains commonly used in health foods. Most strains were resistant to antibiotics but their antibiotic resistance rates were not high: Fos (56.52%), TET (43.48%), CRO (21.74%), AMC (15.22%), GEN (13.04%), RIF (10.87%), CHL (8.7%), CTX (6.52%), VAN (4.35%), and ERY (4.35%). The 45 strains could be divided into 14 pulsed-field gel electrophoresis types, of which the strain numbers of six pulsed-field gel electrophoresis types were more than one. All the Bifidobacterium strains could be divided into nine types by API50CHL biochemical identification. The same species displayed same biochemical typings, expect for B. animalis. Furthermore, the results confirmed that the same pulsed-field gel electrophoresis-type strains had closer antibiotic resistance patterns, and the same biochemical-type strain also had similar antibiotic resistance patterns.

Integrative applications of network pharmacology and molecular docking: An herbal formula ameliorates H9c2 cells injury through pyroptosis

Zhongwen Qi,Zhipeng Yan,Yueyao Wang,Nan Ji,Xiaoya Yang,Ao Zhang,Meng Li,Fengqin Xu,Junping Zhang The Korean Society of Ginseng 2023 Journal of Ginseng Research Vol.47 No.2

Background: QiShen YiQi pills (QSYQ) is a Traditional Chinese Medicine (TCM) formula, which has a significant effect on the treatment of patients with myocardial infarction (MI) in clinical practice. However, the molecular mechanism of QSYQ regulation pyroptosis after MI is still not fully known. Hence, this study was designed to reveal the mechanism of the active ingredient in QSYQ. Methods: Integrated approach of network pharmacology and molecular docking, were conducted to screen active components and corresponding common target genes of QSYQ in intervening pyroptosis after MI. Subsequently, STRING and Cytoscape were applied to construct a PPI network, and obtain candidate active compounds. Molecular docking was performed to verify the binding ability of candidate components to pyroptosis proteins and oxygen-glucose deprivation (OGD) induced cardiomyocytes injuries were applied to explore the protective effect and mechanism of the candidate drug. Results: Two drug-likeness compounds were preliminarily selected, and the binding capacity between Ginsenoside Rh2 (Rh2) and key target High Mobility Group Box 1 (HMGB1)was validated in the form of hydrogen bonding. 2 μM Rh2 prevented OGD-induced H9c2 death and reduced IL-18 and IL-1β levels, possibly by decreasing the activation of the NLRP3 inflammasome, inhibiting the expression of p12-caspase1, and attenuating the level of pyroptosis executive protein GSDMD-N. Conclusions: We propose that Rh2 of QSYQ can protect myocardial cells partially by ameliorating pyroptosis, which seems to have a new insight regarding the therapeutic potential for MI.