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A rare case of miliary tuberculosis accompanying perihepatitis
Ou Jun Kwon1,이석우,장문순,김상철,이지한,김훈 대한응급의학회 2019 Clinical and Experimental Emergency Medicine Vol.6 No.3
Perihepatic capsulitis is associated with various diseases, such as Fitz-Hugh-Curtis syndrome, systemic lupus erythematosus, perforated cholecystitis, perforated hepatic abscess, and tuberculous peritonitis. Miliary tuberculosis is present in about 2% of all reported cases of tuberculosis and is characterized by the widespread millet-like hematogenous dissemination of Mycobacterium tuberculosis. We describe a 24-year-old virgin patient presenting with right upper quadrant and costovertebral angle pain. Diffuse perihepatic capsular enhancement was observed in abdominal computed tomography scans. Chest radiography showed miliary tuberculosis, and a polymerase chain reaction hybridization assay of sputum revealed the presence of M. tuberculosis. Symptoms improved after administering anti-tuberculosis medications. This report describes a rare case of miliary tuberculosis accompanying perihepatitis.
( Ou Yang Qi ),( Pu Wang ),( Jin Huang ),( Jin Bo Cai ),( Jun Yao He ) 한국미생물 · 생명공학회 2013 Journal of microbiology and biotechnology Vol.23 No.3
(R)-[3,5-Bis(trifluoromethyl)phenyl] ethanol is a key chiral intermediate for the synthesis of aprepitant. In this paper, an efficient synthetic process for (R)-[3,5- bis(trifluoromethyl)phenyl] ethanol was developed via the asymmetric reduction of 3,5-bis(trifluoromethyl) acetophenone, catalyzed by Leifsonia xyli CCTCC M 2010241 cells using isopropanol as the co-substrate for cofactor recycling. Firstly, the substrate and product solubility and cell membrane permeability of biocatalysts were evaluated with different co-substrate additions into the reaction system, in which isopropanol manifested as the best hydrogen donor of coupled NADH regeneration during the bioreduction of 3,5-bis(trifluoromethyl) acetophenone. Subsequently, the optimization of parameters for the bioreduction were undertaken to improve the effectiveness of the process. The determined efficient reaction system contained 200mM of 3,5-bis(trifluoromethyl) acetophenone, 20% (v/v) of isopropanol, and 300 g/l of wet cells. The bioreduction was executed at 30oC and 200 rpm for 30 h, and 91.8% of product yield with 99.9% of enantiometric excess (e.e.) was obtained. The established bioreduction reaction system could tolerate higher substrate concentrations of 3,5- bis(trifluoromethyl) acetophenone, and afforded a satisfactory yield and excellent product e.e. for the desired (R)-chiral alcohol, thus providing an alternative to the chemical synthesis of (R)-[3,5-bis(trifluoromethyl)phenyl] ethanol.
A study of Region of Interest coding in JPEG2000
( Yang Ou ),( Ki-jun Kang ),( Bu-kwon Lee ) 한국정보처리학회 2006 한국정보처리학회 학술대회논문집 Vol.13 No.1
One of the most significant characteristics of JPEG2000, the emerging still image standards, is the Region of Interest (ROI) coding. Until now, there have been many proposed ROI methods. However, all of these methods can not be applied completely in applications. In this paper, the ROI coding mechanisms in JPEG2000 is first outlined and the diversity of ROI coding methods is discussed in detail. Then a comparative selection about using a proper ROI method according to ROI applications’ requirements is proposed. Finally the experimental results show that there are also several parameters that control the effectiveness of ROI coding, such as the codeblock size, ROI size, wavelet filter type, the number of wavelet decomposition levels, and ROI importance score.
Beong-Ou Lim,Doo-Pyo Hong,June-Yong Yun,Young-Jun Jeoung,Ju-Yeon Lee,Hae-Gon Chung,Dong-Kug Choi,Wahn-Soo Choi,Bong-Gum Cho,Tae-Kyu Park,Dong-Ki Park 한국약용작물학회 2005 한국약용작물학회지 Vol.13 No.5
Phellinus linteus (PL), one of the immune-regulatory substances, is recognized to play the role in the metabolic process on inflammation and immunity. It has been traditionally used in the oriental medicine to treat inflammatory related disease. The purpose of this study was to evaluate the effects of water extracts of PL on the mesenteric lymph node lymphocytes immune function in the ICR male mice. Control mice received vehicle only. The PL treated mice were administered the respective extract by oral gavages for 4 weeks. IgE concentrations in serum and MLN lymphocytes were significantly lower in PL treated mice than in control mice. PL increased the proportion of CD4+ and CD8+ T cells in MLN lymphocytes. PL significantly decreased Th2 cytokine concentrations and mRNA expression levels in cytokine secretions. Therefore, water extracts of PL modulate inflammatory parameters through regulation of immunoglobulin production resulting from decreased Th2 cytokine secretion and mRNA expression levels and reduce pro-inflammatory cytokine secretion and mRNA expression in MLN lymphocytes.