직장 Dieulafoy 병변으로 다량의 혈변을 보인 1 예

김태영;이상헌;김지현;배영환;정은주;김승만;지삼룡;설상영 인제대학교 2011 仁濟醫學 Vol.32 No.-

Dieulafoy’s lesion is very rare cause of gastrointestinal bleeding, Deiulafoy’s lesion is exposure of non ulcerative, abnormally large tortuous, thick- walled artery in the muscularis mucosa through a small submucosal defect. It is usullay found on stomach antrum and lesser curvature side of the proximal body, and possibly found on any sites throughout whole gastrointestinal tract, but rarely on rectum. The principal of treating Dieulafoy’s lesion was the surgical resection of lesion, but recently remarkable advances in endoscopic technique make endoscopic approach more popular. We report a case of rectal Dieulafoy’s lesion successfully treated with endoscopic hemoclipping in an elderly female patient.

젊은 남자 성인의 칼슘과 철의 영양상태에 관한 연구

박영숙,곽주영,권지혜,류화라 순천향대학교 기초과학연구소 2002 순천향자연과학연구 논문집 Vol.8 No.1

A survey was performed to 174 male young men who were living alone(40 persons) and shared living with friends(4143 persons) in Chungnam province. Their average age was 22.6 years old, height 171.8 ㎝, and weight 65.6 ㎏. Their daily calcium intake level was averaged 271.9±169.1 ㎎, which was 38.8 %RDA. Comparing calcium intake of each mealtime, breakfast, lunch, dinner, and snacks were composed of 18.6%, 30.0%, 34.0% and 17.4%, respectively. Their daily iron intake level was averaged 8.9±10.8 ㎎, which was 74.3 %RDA. Comparing iron intake of each mealtime, breakfast, lunch, dinner, and snacks were composed of 15.4%, 33.6%, 36.3% and 14.7%, respectively. These results suggested that deficiency of the two minerals in young male adults were severe and the nutrient qualities were also poor, no matter of their living alone or with accompanies. The deficiency was more profound in calcium than iron. And we observed iron nutriture differed significantly according to their living status, such as iron intake and its %RDA were significantly worse in single living subjects than the others. However calcium did not show significant difference. We concluded that shared living environment in young male adults could possibly improve their dietary mineral intake levels.

보육교사의 전문성 발달 수준에 따른 이야기 나누기와 조형 활동의 수업 전문성 평가

김지영(Kim Ji-Young),윤진주(Youn Jin-Ju) 한국영유아보육학회 2010 한국영유아보육학 Vol.0 No.60

본 연구에서는 보육교사의 전문성 발달 수준에 따라 이야기 나누기와 조형 활동의 수업을 평가하여 보육교사의 수업 전문성 차이를 살펴보고자 하였다. 연구대상은 G 광역시에 소재한 보육시설에 근무하는 보육교사 84명이다. 연구도구는 백은주ㆍ조부경(2004)이 개발한 전문성 발달 수준 검사 도구와 선행연구 및 관련문헌(김희진ㆍ박은혜ㆍ이지현, 2000; 박승순, 2004; 정영희, 2005; 허미애, 2007)을 참고하여 연구자가 개발한 관찰 평가지를 사용하였다. 자료분석은 보육교사의 전문성 발달 수준 총점을 기준으로 집단(상집단과 하집단)을 구분하고, 각 집단에 따른 수업 전문성의 차이를 알아보기 위하여 독립표본 t-검증을 실시하였다. 연구결과를 제시하면 다음과 같다. 첫째, 전문성 발달 수준이 높은 보육교사는 낮은 보육교사보다 이야기 나누기 활동의 수업 전문성이 높았으며, 특히 이야기나누기의 주제 선정, 사전 준비 및 매체 활용, 소요 시간에 대한 수업 전문성이 더욱 높은 것으로 나타났다. 둘째, 전문성 발달 수준이 높은 보육교사는 낮은 보육교사보다 조형 활동의 수업 전문성이 높았으며, 조형 활동의 선정, 환경 준비, 지도 과정에 대한 수업 전문성에서 모두 높은 것으로 나타났다. 본 연구는 보육교사의 전문성 발달 수준과 수업 전문성은 밀접한 관련이 있음을 증명하는 것으로, 연구의 결과는 보육교사의 수업 전문성 발달 수준을 높이기 위한 현직 교사교육 프로그램 개발에 필요한 기초 자료로 활용될 수 있을 것이다. This study examines differences in instructional expertise among childcare teachers in relation to their professional development levels through evaluation of their story discussion and art activity classes. Employed as the subjects of this study were 84 teachers working for childcare institutions in G Metropolitan City. A questionnaire was used as a research tool after being prepared on the basis of a professional development test tool developed by Baek Eun-ju and Jo Bu-gyeong (2004) as well as related previous studies and bibliographies (Kim Hee-jin, Park Eun-hye, Lee Ji-hyeon, 2000; Park Seung-sun, 2004; Huh Mi-ae, 2007). For data analysis, the teachers were divided into two groups (the upper group and the lower group) in accordance with their professional development level scores. Independent t-tests were conducted to determine the differences between the two groups in instructional expertise. The findings of this study can be summed up as follows. First, childcare teachers with high levels of professional development displayed higher levels of instructional expertise in story discussion class than those with low levels of professional development. The difference was particularly conspicuous in topic selection, class preparations and the use of media, as well as time allotment. Second, childcare teachers with high levels of professional development displayed higher levels of instructional expertise in art activity class than those with low levels of professional development. The former group turned out to have better instructional expertise than the latter group in all the related areas of art activity selection, arrangement of learning environments, and the effectiveness of instructional processes. This study showed that childcare teachers' professional development levels are closely related to their instructional expertise. The findings may be used as basic materials in developing program models designed to enhance professional development levels of childcare teachers.

구강균에 대한 각종 한약제의 증식 억제

정영건,지원대,김성영,곽동주,서수교,백경연 한국위생과학회 1997 한국위생과학회지 Vol.3 No.1

The effect of oriental medicines an the growth of oral bacteria(B. pumilus JU4, B. coagulans JU6, B. subtilis var globigii JU7 and B. subtilis var. globigii JU9) which were isolated from teeth, gums and tongues of patients was investigated. lt was shown that the water extracts of Glycyrrhiza glabra L. var. glandulifera Regel et Zucc., Schizandrae Fructus and Coptidis Rhizoma have the strong antimicrobial activity against every test organism. Especially, the water extract of Schizandrae Fructus has the most antimicrobial activity against all test bacteria of which MIC were the same as 0.25%. The growth of oral bacteria B. pumilus JU4 was inhibited by addition of the water extracts of Glycyrrhizae Radix, Schizandrae Fructus and Coptidis Rhizoma in the concentration of 0.9%, 0.2% and 0.1% respectively. It was tested that specific growth rates of B. pumilus JU4 in each concentration of the water extracts of Glycyrrhizae Radix, Schizandrae Fructus and Coptidis Rhizoma. From the results, the test showed that mean of specific growth rates of B. pumilus JU4 decreased 102%, 186% and 210% in 3% concentration of the water extracts of Glycyrrhizae Radix, Schizandrae Fructus and Coptidis Rhizoma more than those in control respectively.

McCoy 세포에서 Chlamydia trachomatis의 병원성 인자에 관한 연구

강정숙,최지영,차영주,김영주,김덕례,여명구,박열 조선대학교 생명과학연구소 1998 생명과학 연구 Vol.6 No.-

본 연구는 병원성 세균인 Chlamydia trachomatis(C. trachomatis)가 숙주세포에침습시 C. trachomatis의 병원성 인자와 C. trachomatis와 상호작용하는 숙주 세포막의 인자를 규명함으로써 숙주세포에 대한 감염율을 향상시켜 보다 향상된 진단 방법을 개발하기 위하여 수행하였다. C. trachomatis로 감염된 세포에서 기본소체의 막 단백질을 분리한 결과 각 혈청형의 39 kDa과 42 kDa에서 major outer membranes(MOMPs)이 관찰되었으며, 혈청형 E와 G의 MOMPs는 42.5 kDa으로 동일하였지만 혈청형 F, H, I, 그리고 K의 MOMPs는 각각 다르게 관찰되었다. C. trachomatis가 숙주세포로 침습시 관련된 병원성 인자에 대하여 조사하고자 단층세포로 배양된 배양용기에 C. trachomatis를 24, 48 그리고 73시간대별로 접종시켜 관찰한 결과 72시간의 MOMPs의 양이 가장 많이 증가하였으며 이 결과로 MOMPS이 C. trachomatis 병원성에 중요한 작용을 함을 확인할 수 있었다. C. trachomatis가 침습시 숙주세포의 막 단백질 변화양상을 관찰하기 위해 정상세포와 C. trachomatis로 1, 2, 3 그리고 4시간대별로 접종 시간을 달리한 숙주세포의 막 단백질을 분리한 결과 42 kDa의 단백질 양이 Chlamydia에 감염된 세포 내에서 증가됨을 관찰할 수 있었다. 이로 42 kDa의 막 단백질이 침습시 숙주세포 표면에 대한 수용체로서 작용함을 알 수 있었다. The present study was performed to analyze the pathogenic factors involved in the invasion process of Chlamydia trachomatis(C. trachomatis) into McCoy cells. In this study, elementary bodies(EBs) of C. trachomatis serotypes(E, F, G, H, I, K and LGV) could be isolated by the method of Percoll density gradient centrifugation and the pathogens of serotypes were also compared from whole-cell lysates by using sodium dodecyl sulfate-polyacrylamide gel elelectrophoresis. All chlamydial serotypes showed a single predominant protein ranging from 39 to 42 kDa. The major outer membrane proteins(MOMPs) of the E and G serotypes had an identical molecular weight of 42.5 kDa. In contrast, the MOMPs of the F, H, I and K serotypes were showed different molecular weights of MOMPs. By immunoblotting with anti-MOMP antibody it was revealed that the quantify of MOMPs was time-dependently increased when McCoy cells were infected with Chlamydia for 24, 48 and 72 hr. These results indicated that MOMPs are closely related to chlamydial infection into the host cell.

심혈관계 질환으로 관상질환 집중치료실에 입원한 환자들의 혜후 측정을 위한 APACHEⅢ점수 체계의 임상적 유용성

이공섭,이창선,최현주,홍종서,강지향,김도형,이민영,오인균,김병엽,김상억,김학찬,한승혜,이재용,지영우,안경주 대한순환기학회 2000 Korean Circulation Journal Vol.30 No.8

학교 지역문화교육을 위한 지역협의체 구성에 관한 연구

김영순,임지혜,배현주 한국문화교육학회 2011 문화예술교육연구 Vol.6 No.2

The aim of this study was to search conditions activating the regional consortium for regional culture education in schools. Results of this study are follows: the regional consortium consists of parents of students, communities, schools, school boards, public institutes, and NGO groups. The consortium contribute the educational support and development for student activities in schools. Furthermore the consortium make an offer to coordinate and facilitate the delivery of information, resources, and services to students, educators, employers, and the community. Therefore, the consortium might be best described as "matchmakers" that help ensure that our customers are able to easily connect with providers of the services they need. The consortium will be made up of a network of service providers from across its region that all collaborate in helping to connect the local education and school communities. 본 연구에서는 지역 사회의 인적·물적 자산을 활용한 문화적 체험활동 교육이 활성화되고 정착되기 위한 방안으로 학교와 지역사회가 밀접한 관계를 형성할 수 있는 지역협의체를 구성하는 안을 제시하였다. 이를 위해 지역문화교육에 필요한 지역협의체에 대한 문헌연구를 수행하였고, 이와 유사한 실제 사례를 찾아 관련 전문가를 대상으로 한 심층인터뷰 결과를 정리하고 시사점을 도출하였다. 연구결과, 지역협의체는 지역특수성, 전문성, 개방성, 공공성, 지속성의 기본원칙을 전제로 하여 교육행정기관, 지자체 행정기관, 민간 및 공공기관, 학교 등의 협력을 통해 구성될 수 있다. 또한 지역에서의 문화적 체험활동의 효율적인 운영을 지원하기 위해 1) 지역사회 내 교육기부 협력기관을 모색 및 발굴·연계, 2) 지역의 교육 인프라 접근성 향상, 3) 지역의 문화 교육 자원 간 네트워크 확장, 4) 지역 내 긍정적인 담론 형성을 위한 홍보 및 인식 개선, 5) 지역문화교육 프로그램 수행 과정의 성찰 등의 역할을 수행해야 한다. 지역협의체를 통한 학교와 지역교육자원의 연계 방안은 교육자원의 유형과 교육운영 주체에 따라 분류될 수 있었고, 강동구청과 대구광역시교육청의 예를 통해 지역문화교육 지원의 구체적인 사례를 살펴볼 수 있었다. 이와 같이 본 연구에서 제안한 지역협의체의 구성은 지역문화교육의 활성화를 위한 초석을 마련해 줄 것이라고 기대해 본다.

조혈모세포이식 후 발생한 주폐포자층 폐렴에 대한 고찰

주지현,최정현,이동건,백지연,고윤호,이혜정,김세희,신호진,박윤희,박지영,김유진,신완식,김춘추 대한감염학회 2001 감염 Vol.33 No.4

Background : Pneumocytitis cainii pneumonia (PCP) can occur in immunocompromised hosts especially such as AIDS or cancer patients. Although recent research had focused on PCP in AIDS patients, few studies have described the clinical presentations of PCP in recipients of stem cell transplantation (SCT). We evaluated the clinical manifestations of PCP in SCT patients admitted at St. Mary's hospital, Seoul, Korea. Methods : The medical records of 17 PCP patients undergoing SCT between Feb. 1998 and Feb. 2000 were reviewed. The diagnosis of PCP was confirmed through the demonstration of Pneumocytitis cainii via either cytology of brochoalveolar lavage (BAL) or histological technique of lung biopsy. CMV disease and CMV infection were confirmed by BAL culture and antigenemia respectively . Results : Seventeen patients were all recipients of allogeneic SCT and 7 of 17 patients were performed non-sibling SCT. Patients presented with symptoms including brief period (4 ∼23 days) of fever (76%), dyspnea (70%), cough (64%), and signs such as rare(58.8%), Sixteen patients (94%) had been receiving immunosuppressive agent such as cyclosporine A (64%) or Fk506 (35%) without PCP prophylaxis. Eleven patients (64%) were treated with corticosteroid with mean dose of 16 mg/day prednisolone and mean duration of 4.6 months after post-SCT period. Twelve patients were co-infected with CMV. Another co-infected miCroorganisms were Pseudomonas aeruginosa, Mycobacterium tuberculosis, herpes simplex virus, parainfluenza virus, Average duration of treatment with trimethoprim-sulfamethoxazole (TMP/SMX) was 21 ±9 days. Four patients died, and three of them were related with PCP. Conclusion : PCP developed frequently in patients who were taking immunosuppressive drug due to graft versus host disease or were not taking TMP/SMX prophylaxis. High risk patients showing fever, cough, or dyspnea should be considered to take early bronchoscopic intervention for detection of PCP. When treat for PCP, it also be considered to the possibility of coinfection such as CMV. (Korean J Infect Dis 33:273∼279, 2001)

갑상선기능저하증에 합병된 중증 전자간증과 심외막 삼출액으로 의한 심장탐폰을 동반한 임신 1예

구희주,최원석,이지영,손인숙,김수녕 건국대학교 의과학연구소 2001 건국의과학학술지 Vol.11 No.-

Hypothyroidism presenting during pregnancy is rare, probably due to the lower incidence of hypothyroidism during reproductive years. And hypothyroidism rarely complicates pregnancy because most hypothyroidism is accompanied by amenorrhea and anovulation. Risk of maternal complications of hypothyroidism including preeclampsia, placental abruption, anemia, postpartum hemorrhage, cardiac dysfunction are increased. Hypothyroidism accompanies pericardial effusion frequently. But the diagnosis of pericardial effusion is usually made incidentally by routine check-up because the patient rarely complains any symptoms of pericardial effusion. Moreover it is extremely rare that pericardial effusion makes the presenting sign of hypothyroidism. We experienced a case of preeclampsia with pericardial effusion in hypothyroid parturient that needed pericardial window operation with emergency cesarean section. So we present this case with a brief review.

인간-보행동작과 신발디자인 연구

옥영주,최지희 경성대학교 2000 論文集 Vol.21 No.1

The purpose of this paper is to indicate the property in walking engineering as a factor of human-engineering which is concerned in footgear-design, and to infer the present situation of the footgear-design in this country. The conclusion is: 1. The facets of human-engineering in the footgear -design consist of walking engineering, posture engineering, physical anatomy, somatological statics, physics and material engineering. 2. The componts determinated in walking engineering are flooring(ground) condition, walking speed-pace and the time required per one walking. 3. Especially, the characteristics in the walking and movement for the infant and the old age have to be considered in the move mode and walking-change process according to the human development stage accompanied by observation. 4. The footgear-design approach and human engineering are connected with the wearing-test study, the size-standardization, the material-lightweight, the structur-functioning of the footgear, the environmental change, and the footgear movement.