건강한 성인의 체위변화가 혈압과 맥박에 미치는 영향

김종임,홍춘실,박인숙 충남대학교 의과대학 지역사회의학연구소 1991 충남의대잡지 Vol.18 No.1

This study investigated the effect of changing position between standing and sitting groups on blood pressure and pulse rate of young men. two minutes before standing or sitting, the baseline blood pressure and pulse rate were measured. Blood pressure and pulse rate were recorded immediately, 2 minutes and 4 minutes after standing or sitting position. Differences in blood pressure and pulse rate between standing and sitting position were evaluated. The results obtained were as follows: 1. Systolic and diastolic blood pressure were increased after standing or sitting position immediately, after 2 minutes, after 4 minutes than those of supine position. 2. Systolic and diastolic blood pressure after sitting position immediately were lower than those of standing position. 3. Pulse rate were increased continuously after standing or sitting position. Form these results, it may be concluded that systolic, diastolic blood pressure and pulse rate were slightly increased after standing or sitting position. But systolic, diastolic blood pressure and pulse rate after sitting position immediately were, lower than those of standing position immediately.

제주도 감귤원 토양에서 GUS, RF, AF 지수를 이용한 농약의 용탈잠재성 평가

오상실,현해남,문두길,정종배 한국환경농학회 2002 한국환경농학회지 Vol.21 No.1

유기물함량이 다른 감귤원 토양을 대상으로 CUS, RF 및 AF값을 비교하여 감귤원에서 많이 사용되고 있는 농약 종류별 지하수 오염 잠재성을 평가하였다. GUS에 의하면 metribuzin과 metolacholr는 조사된 모든 토양등에서 용탈 가능성이 큰 것으로 평가되었으며, alachlor와 lin-uron도 대부분 토양에서 용탈가능성이 높은 것으로 평가되었으며 linuron의 경우에는 특히 비화산회토양에서 용탈의 가능성이 매우 높은 것으로 나타났다. Diuron과 diniconazole은 대부분 토양에서 용탈 가능성이 없는 것으로 평가되었고, chlorothalonil과chlorpyrifos는 유기물 함량에 관계없이 용탈 가능성이 없는 것으로 평가되었다. RF에 의한 평가에서는 diniconazole, chlorothalonil, chlorpy-rifos는 모든 토양에서, linuron과 diuron은 일부 비화산회토를 제외한 모든 토양에서 이동성이 매우 낮은 것으로 분류되었으며,metolachlor와 alachlor는 대부분의 토양에서 이동성이 보통인 것으로, metribuzin은 유기탄소함량이 낮은 토양에서 오염 잠재성이 있는 것으로 평가되었다. AF에 의하면 diniconazole, chlorothalonil, chlorpyrifos는 화산회토, 비화산회토에 관계없이 지하수 오염 잠재성이 없는 것으로 평가되었으며, 반면 metribuzin은 화산회토, 비화산회토에 관계없이 오염 잠재성이 있는 것으로 평가되었다. Metolachlor는 비화산회토에서 지하수 오염 잠재성이 있는 것으로 평가되었고, al-achlor, linuron 및 diuron은 유기물 함량이 낮은 일부 비화산회토에서만 지하수 오염 잠재성이 우려되는 것으로 나타났다. 농약의 용탈잠재성은 용해도, 흡착성, 잔류성 등의 약제 자체의 특성과 함께 유기물 함량, 투수성 등 토양의 물리화학적 특성에 따라서 결정된다. 본 연구의 결과를 보면 이러한 일반적인 원칙이 각 농약의 용탈잠재성 지수에 그대로 반영되었는데, 용해도가 높고, 흡착성이 약하며 잔류성이 긴 약제일수록 대부분의 토양에서 용탈잠재성이 큰 것으로 나타났다. 토양의 특성 중에서는 특히 농약의 흡착에 직접 영향을 미치는 유기물 함량이 용탈잠재성 지수를 결정하는 중요한 요인으로 볼 수 있는데, 본 연구의 결과에서도 일반적으로 유기물 함량이 높은 화산회 토양에서는 농약의 용탈잠재성이 비화산회토양에 비교하여 낮은 것으로 나타났으며, 용해도가 높고 흡착성이 매우 낮은 약제인 metribuzin의 경우에도 투수성이 상대적으로 높은 화산회 토양에서보다 투수성이 낮은 비화산회토양에서 용탈 가능성이 높게 평가된 것으로 보아 대부분 농약의 용탈잠재성을 결정하는데 있어 토양의 투수성보다도 유기물 함량이 더욱 중요하게 영향을 미치는 것으로 판단할 수 있다. 따라서 비화산회토를 위주로 한 유기물 함량이 낮은 토양이 분포된 지역의 지하수가 농약의 오염에 취약할 것으로 판단할 수 있으며, 이들 지역에서는 용탈잠재성이 높은 것으로 평가된 약제들의 사용을 최대한 제한함으로써 제주도 지하수의 농약 오염을 방지할 수 있을 것이다. 물론 제주도 감글원에서는 토양의 유기물 함량과 약제의 흡착성을 우선적으로 고려하여 사용할 농약을 선택해야 할 것으로 보이나, 그 외 약제의 잔류성, 사용량, 사용시기와 함께 기후조건, 토양의 투수성, 토충의 깊이, 지하수 깊이 등의 지역적인 특성들이 농약의 용탈잠재성에 미치는 영향도 더욱 구체적으로 파악되어야 할 것이며 농약의 선택 과정에서도 이러한 특성들이 앞으로 고려되어야 할 것이다. Contamination of groundwater by agrochemicals used in the regional-scale is now a major environmental problem, and this is especially true for Cheju island where virtually all potable water is from groundwater. The objective of this study was to assess leaching potential of eight pesticides in soils of citrus orchards using groundwater ubiquity score (GUS), retardation factor (RF) and attenuation factor (AF). Considering GUS estimated in 30 citrus orchard soils, metribuzin and metolachlor were classified as leacher, alachlor in volcanic ash soils and linuron in non-volcanic soils were classified as leacher, but chlorothalonil and chlorpyrifos were classified as non-leacher. For RF values, metribuzin was classified to be mobile in soils of low organic carbon, metolachlor and alachlor were classified to be moderately immobile in most soils, but linuron, diuron, diniconazole, chlorothalonil and chlorpyrifos were all classified to be very immobile. For AF values, diniconazole, chlorothalonil, and chlorpyrifos were classified to be very unlikely leachable in all of the soils, metribuzin was classified to be likely leachable, and metolahclor, alachlor, linuron and diuron were classified to be leachable only in non-volcanic soils. Although there were some variations in the relative potential of leachability of pesticides estimated with the three different indices, the ranking was essentially determined on the base of the intrinsic properties of the chemicals and environmental properties. Among the eight pesticides, metribuzin, metolachlor, and alachlor, which have high water solubility and low K_(oc) values, have a significant leaching potential especially in non-volcanic ash soils of low organic carbon. But diniconazole, chlorothalonil, and chlorpyrifos, which have low water solubility and high K_(oc) values, were classified to be very immobile in all of the soils. Therefore, to lower the possibility of pesticide contamination of the groundwater in Cheju island, those pesticides which have high water solubility and low K_(oc) values should be used with care in soils of low organic carbon including non-volcanic ash soils.

페디그리 사료 섭취에 의한 급성신부전증의 치료 1례

김영실,신영지,박정희,김명철,신상태,조종기,김덕환 忠南大學校 獸醫科大學 動物醫科學硏究所 2005 動物醫科學硏究誌 Vol.13 No.-

A 4 years old male poodle dog with gastro-intestinal distress was referred to the Veterinary Medical Teaching Hospital of Chungnam National University. The patient was presented with history of vomiting, hemorrhagic diarrhea and inappetence. Laboratory evaluation revealed that WBC (23.8 x 10^(3)/㎕). BUN (87.9 ㎎/㎗), creatinine (7.3 ㎎/㎗) and phosphate (9.6 ㎎/㎗) was elevated, and proteinuria, hematuria and bilirubinuria were detected on urinalysis. Increased renal cortical echogenicity and parenchymal calcification of kidney were observed by ultrasonography. Based on the findings of history, clinical signs, laboratory assessment and ultrasonography, it was diagnosed as acute renal failure. The present patient showed favorable therapeutic response by fluid therapy. diuretics, peritoneal dialysis and blood transfusion.

한센사업에서의 재활사업에 대한 한센전문기관의 역할에 대한 분석

김종필,김연실,고영훈 대한나학회 2003 대한나학회지 Vol.36 No.2

찬물섭취가 정상성인의 혈압및 심박동수에 미치는 영향

김종임,홍춘식,박인숙 충남대학교 의과대학 지역사회의학연구소 1989 충남의대잡지 Vol.16 No.2

This study was undertaken to elucidate effect of ingesting cold water on blood pressure and pulse rate of normal healthy men with the purpose of furnishing basic data for nursing intervention of heart disease patients. The subjects for this study were normal healthy men consisting of 15 women and 15 men in age from 21 to 33 years. The subjects consisting of 30 men drank 240cc cold water on the first day, ingested 720cc cold water on the second day. Blood pressure and pulse rate were taken in a sitting position through all trial. Changes of blood pressure and pulse rate after ingesting cold water were compaired with those of pre-ingestive period. The results of the study were as follows. 1. There were no significant changes in blood pressure and pulse rate after ingesting 240cc cold water comparing with those of pre-ingestive period. 2. Changes of blood pressure and pulse rate were significantly decreased after ingesting 720cc cold water comparing with those of pre-ingestive period. In conclusion, the researchers think it is necessary that a nurse must give her careful consideration to prevent the potential crisis of an ingestion of cold water in coronary care unit and field of critical care.

비소중독된 흰쥐의 장기중 비소 축적에 미치는 팔진탕의 영향

임종필,서은실,김훈,강창수 又石大學校 1998 論文集 Vol.20 No.-

Sodium arsenate and Paljin-Tang extract, a herbal restorative were treated p.o. 20 ㎎/㎏ and 500 ㎎/㎏, respectively, and concurrently to rats, and examined the variation of body weight, the accumulation of arsenic in organs. The results obtained in this study were as follows: 1. Paljin-Tang extract (PJT) resulted in the increase of body weight and the increase ratio of body weight in arsenic-treated group was dropped but the group of concurrent administration with PJT showed significant recovery. 2. The accumulation of arsenic in liver of arsenic-treated group increased but the group of concurrent administration with PJT showed significant decrease compared with arsenic-treated group. 3. The ratio of liver weight / body weight of arsenic-treated group increased but the group of concurrent administration with PJT showed significant decrease compared with arsenic-treated group.

골프연습장 고객의 라이프스타일과 이용의도에 관한 연구

이종희,한광령,강신일 경희대학교 체육과학연구소 2004 體育學論文集 Vol.32 No.-

The purpose of the study was to examine the relationship among life-style and perceived service quality and intention of using of golfer's of participating golf exercise places. In order to achieve this purpose four research questions were established. The first question we that there will be relationship controlling to variables between lifestyle and perception of service quality of golf participators. Second one was that there will be relationship controlling to variables between lifestyle and consumer intention of golf participators. Third one was that there will be influence golfer's lifestyle, perceptions of service quality and consumer intention of participating on golf exercise places. 400 of above 30 age persons completed questionnaires. Of participations valid data were 378. They completed a modified inventory on the life-style, perception of service quality, and consumer's intention. More details, lifestyle Scale modified by Su, and perception of service quality by go, and consumer intention scale by Beard & Ragheb were using after modifying scale to investigate the purpose of this study. Results were analysed in quantitative approaches. Data were collected through self-administered survey. The three most meaningful results of the study were as follows; First, there was influenced to relationship between lifestyle and perception of service quality. Second, there was influenced to relationship between lifestyle and consumer's intention. Third, there was influenced to relationship among lifestyle, perception of service quality and consumer's intention.

DHA의 lipoxygenation에 의한 17-H(P)DHA 의 제조 및 LC/MS/MS를 이용한 구조분석

이은실,이은주,강종성 충남대학교 약학대학 의약품개발연구소 2007 藥學論文集 Vol.22 No.-

Docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) are essential fatty acids and necessary for the development of brain, nerve system and retina. Recently, novel hydroxy compounds generated from DHA and EPA showing various biological activities were reported. In this study, hydroperoxy compound of DHA was prepared by incubating 15-lipoxygenase (15-LOX) and DHA, and was purified and analyzed by HPLC. The purified compound (MW 360) with the absorption maximum of 238 nm was identified as 17-hydroperoxy DHA (17-HPDHA). 17-HPDHA was reduced to a hydroxy compound by sodium borohydride and identified as 17-hydroxy DHA (HDHA) by LC/MS/MS. This method could afford to gain the commercially unavailable precursor of biologically active mediator.

악성 섬유성 조직구종의 기원에 관한 면역조직화학적 및 초미세형태학적 연구

전호종,임성철,강종식,김일,황호원 朝鮮大學校 附設 醫學硏究所 1991 The Medical Journal of Chosun University Vol.15 No.1

Malignant fibrous histiocytoma(MFH) was first terminologically introduced in 1963 to refer to a group malignant soft tissue tumors characterized by a stonform growth pattern and these tumors are a oup of sarcomas composed of cells morphologically resembling fibroblast and histiocvte. The histogeisis of MFH is still controversial, but a more complete appreciation of it's morphogenesis has been ovided by tissue culture and ultrastructural studies. In the present study, ultrastructural and immunohistochemical studies of seven cases of MFH disclosee maturation and development of principal types of cells constituting MFH and immunohistochemical actions to investigate the histogenesis of malignant fibrous histiocytoma. The results obtained were as follows. Malignant fibrous histiocytoma composed of different portions of fibroblast-like cells, histiocyte-like cells, cells intermediate between histiocyte-and fibroblast-like cells, multinucleated giant cells, undif ferentiated cells, xanthomatous cells and myofibroblast. The principal cell types of malignant fibrous histiocytoma were fibroblast-like, histiocyte-like, intermediate (fibrohistiocytoid) and undifferentiated cell. There were cells bearing variable stages of differentiation along the fibroblastic and histiocytic lines from undifferentiated cells. 2. There was no difference in cellular composition ultrastructurally between storiform-pleomorphic, myxoid and inflammatory subtypes. 3. Junctional complexes were shown in fibroblast-like, histiocyte-like cells, intermediate cell and myofibroblasts. Long desmosomes were observed in histiocyte-like cells, intermediated cells and myofibroblasts, Paired subplasmalemmal densities were also shown in fibroblast-like cells and. intermediate forms. 4. Immunohistochemical reactions revealed strong staining reactions for α1-antitrymotrypsin in histiocyte=like cells and multmucleated giant cells. Vimentin was reactive for fibroblast-like cells, histsiocyte-like cells and multinucleated giant cells. However, no evidence of staining reactions for α1-antitrypsin, a1-antichymotrypsin, vimentin, lysozyme in the cells of early stage of differentiation along the fibroblast and histiocyte-like cells from the undifferentiated cells. 5. In conclusion it is suggested that malignant fibrous histiocytoma may be considered a primitive mesenchymal tumors originating from undifferentiated cells.

난소의 소세포암종, 고칼슘혈증형 대세포 변종 : 1예 보고 A Case Report

이종실,이종학,김유경,박선후,고경혁 대한병리학회 2001 Journal of Pathology and Translational Medicine Vol.35 No.4