응급실 내원 환자의 만족도 평가 및 관련 요인에 대한 연구

서강석,감신,박정배,이정헌,김종근,윤영국,곽경숙,이원기,우석정 大韓應急醫學會 1998 대한응급의학회지 Vol.9 No.4

Background: To examine the influencing factors on patients' satisfaction in the emergency department(ED) for quality assurance. Methods: Patients who visited to the ED were prospectively investigated from November 1 to December 31, 1997. Authors developed questionnaire to investigate influencing factors on patients' satisfaction. A Chi-square test and LISREL 7.0 were applied for statistical analysis. Results: Patients' satisfaction was significantly related to physical environment variables, accessibility variables, kindness of hospital personnel variables, and patient's trust for doctors variables. In path analysis, willingness for revisit was influenced by patients' satisfation, accessibility, physical environment, patients' trust for doctors in order, and willingness for recommendation was influenced by accessibility, patients' satisfaction, and kindness of hospital personnel in order. Conclusions: The influencing factors on patients' satisfaction are physical environment, accessibility, kindness of hospital personnel, and patient's trust for doctors. Willingness for revisit and willingness for recommendation are influenced by patients' satisfation. In spite of some limitations, the results of this study can be used as a baseline information for exploring the influencing factors on patients' satisfaction. Further comprehensive research efforts should be made on the study of patients' satisfactoin in the ED.

개에서 피지선 과형성의 진단 및 치료 증례

박희서,손화영,정성목,송근호,조종기,이영원,신상태,김명철,김덕환,박성준 충남대학교 수의과대학 동물의과학연구소 2004 動物醫科學硏究誌 Vol.12 No.-

An eleven year old castrated male Maltese was presented to the Veterinary Medical Teaching Hospital of Chungnam National University. In physical examination, approximately 0.5 cm round mass was observed on tail base. This small elevated mass has also shown alopecic and firm configuration. It was differentially diagnosed as sebaceous adenoma and hyperplasia by fine needle aspiration. After surgical removal, the sample was diagnosed as sebaceous hyperplasia by histopathological examination. It has not yet shown any signs of recurrence and prognosis has teen good.

비화농성 삼출성 복수를 동반하는 질환에서 복막 침생검의 진단적 의의

정종훈,서용태,오덕환,채종구,정춘해,조건국 朝鮮大學校 附設 醫學硏究所 1986 The Medical Journal of Chosun University Vol.11 No.1

Percutaneous needle biopsies of peritoneum with Abrams needle and Cope needle were done un 64 patients with non-purulent exudative ascites, who was admitted to the department of internal medicine, Chosun University hospital, from January 1978 to Deccmber 1983. The diagnostic significance and safety of the needle biopsy was estimated. The results were as follows. 1. Adequate peritoneal tissue for pathological diagnosis was obtained in 53 cases(82.8%) among 64 cases. (Abrams needle 84.8%, Cope needle 80.6%) 2. Definitive diagnosis was obtained in 31 cases among 53 cases (58.6%). (Tuberculosis 23 cases, malignancy 8 cases). 3. As compared final diagnosis with biopsy result, the rate of final diagnosis corresponding with biopsy diagnosis was 58.8% in tuberculosis and 26.3%, in malignancy, but the rate of biopsy diagnosis corresponding with final diagnosis was 100% in both tuberculosis and malignancy. 4. Cases of chronic non-specific inflammation which were diagnosed by biopsy were 13cases(24.5%)among 53 cases, and among these cases, tuberculosis was 69.2% and malignancy 30.8% on final diagnosis and among 53 cases, histologically normal was 9 cases(16.9%) of which 33.3% was tuberculosis and 66.7% was malignancy on final diagnosis. 5. Of the malignant cases on final diagnosis, Positive cytologic examination of ascitic fluid was 16.7% 6. Primary losions of cancerous peritonitis were stomach cancer (38.9%) hepatocellular cancer(22.2%) colon cancer (11.1%) ovarian cancer (11.1%) Pancreatic cancer (5.6%). 7. Complication of percutaneous peritoneal biopsy was local swelling with leakage of ascitic fluid and the accident rate were 36.4,% in Abraham needle and 3.2% in Cope needle.

사매가 Ovalbumin감작으로 유발된 천식 생쥐 모델에서 기관지염증 억제에 미치는 영향

임중근,노성수,길기정,이영철,서영배 대한본초학회 2005 大韓本草學會誌 Vol.20 No.1

Asthma is a chronic inflammatory disease of the airways, characterized by airway eosinophilia, goblet cell hyperplasia with mucus hypersecretion, and hyper-responsiveness to both inhaled allergens and nonspecific stimuli. Eosinophil are important in the pathogenesis of asthma, with release of inflammatory mediators such as histamine, leukotrienes, cytokines, and IgE after exposure to allergen. Objectives : This research investigates the effect of the extract of Duchesnea chrysanta (EDC) on OVA-indued asthma murine model. Methods : After i.p of C57BL/6 mice, OVA sensitization (day 0) were challenged intratracheally with OVA on days 8 and 21. EDC administered weeks 8, blocked the airway inflammatory response to OVA assessed 24 h after the last OVA challenge on day 22. Results : The CC chemokine receptor 3 (CCR3) is expressed by eosinophils, mast cells, and Th2 cells. The role of CCR3 in a murine model of allergic skin inflammation induced by repeated epicutaneous sensitization with ovalbumin (OVA), and characterized by eosinophil skin infiltration, local expression of Th2 cytokines, and airway hyperresponsiveness (AHR) to inhaled antigen. The administration of EDC during OVA inhalation significantly reduced CCR3 plays an essential role in eosinophil recruitment to the skin and the lung and in the development of AHR.. EDC extract reduced total lung cells and eosinophils in bronchoalveolar lavage fluid, airway tissue eosinophilia, goblet cell hyperplasia, mucus secretion, and peribronchial edema. The inhibitory effect on airway eosinophilia and AHR was associated with reduced levels of IL-4, IL-5, and IL-13 in the bronchoalveolar lavage fluid as well as reduced serum levels of OVA-IgE. We show that OVA inhalation following OVA immunization increased airway responsiveness to induced IL-113, IL-4 and IL-5 mRNA expression in the lung tissue. The administration of EDC during OVA inhalation significantly reduced this increased airway hyperresponsiveness and also inhibited airway inflammation. Conclusions : These results support EDC as a therapeutic target in asthma and indicate that selective EDC inhibitors can reduce allergic airway inflammation.

TRISS Method를 이용한 외상 환자 관리의 평가

윤영국,서강석,이정헌,김종근,감신 대한응급의학회 1996 대한응급의학회지 Vol.7 No.2

Trauma is well known as a major cause of death and disability in Korea, but we do not have a optimal method to evaluate the trauma patients effectively. The purpose of this study was to predict the prognosis and mortality of the trauma patients and to evaluate the quality of trauma care by TRISS method. A retrospective study of 100 cases of trauma victims who visited to emergency room and was admitted to surgical intensive care unit of Kyungpook University Hospital from January 1994 to December 1995 by TRISS method was made. In this study, we have found out following results. 1. Sex ratio of male to female was 4:1 and the mean age was 44 years. 2. Analysis of injury mechanism showed high incidences of traffic accident(71%), fall down(14%), cultivator(5%), penetrating trauma(3%) in order of frequency. 3. A comparison between survivors and deaths showed difference in TS(14.81±1.31 vs.13.64±1.43), RTS(7.26±0.82 vs. 6.78±10.24 vs. 37.45±11.05), TRISS Ps-1 TS and ISS(0.93±0.11 vs. 0.79±0,15), and TRISS Ps-2 by RTS and ISS(0.89±0.15 vs. 0.73±0.19). 4. By TRISS method, unpredicted outcomes occurred in 11 of 100 with 10 unpredicted deaths and 1 unpredicted survivor by TRISS-1 and unpredicted outcomes occurred in 14 of 100 with 9 unpredicted deaths and 5 unpredicted survivors by TRISS-2. 5. The most common cause of death was chest trauma(36.4%). 6. The Z statics, quantitating the difference in the actual number of deaths and the predicted number of death, using TRISS-1 method was 0.84 and using TRISS-2 method was -0.57. The authors conclude that the real dead patients exceeded the predicted outcome in TRISS-1 and the real dead patients were less than the predicted outcome in TRISS-2, and our patient management as well as application of this method should be analyzed for accurate outcome. In conclusion, TRISS method offers a good approach for predicting the prognosis and mortality of the trauma patient and evaluating trauma care.

자연기흉의 임상적 고찰

이정헌,서강석,김종근,윤영국 大韓應急醫學會 1997 대한응급의학회지 Vol.8 No.1

Spontaneous pneumothorax is an accumulation of air in the pleural space with collapse of the lungs in the absence of external chest trauma. In this study, 175 cases of spontaneous pneumothorax experienced at emergency room of Kyungpook University Hospital from July 1995 to June 1996 were analyzed retrospectively. The results were summarized follows: 1. Sex ratio of male to female was 6.6:1 and the mean age was 36.7 years. 2. In clinical symptoms, dyspnea was 85 cases(48.6%), chest pain 67 cases(38.3%), chest discomfort 18 cases(10.3%), coughing 2 cases(1.1%), and others 3 cases(1.7%). 3. In etiology of spontaneous pneumothorax, primary spontaneous pneumothorax was 118 cases (67.4%) and secondary spontaneous pneumothorax 57 cases(33.6%). The underlying pathologic lesion of secondary spontaneous pneumothorax showed pulmonary tuberculosis in 50 cases(28.6%), COPD in 5 cases(2.9%), bronchial asthma in 1 case(0.6%), and pneumoconiosis in 1 case(0.6%). 4. The incidence of recurrence was as follows; no previous history in 123 cases(70.3%), second attack in 35 cases(20.0%), third attack in 15 cases(8.6%), fourth attack in 1 case(0.6%), and fifth attack in 1 case(0.6%). 5. The interval of recurrence after last attack was as follows; less than 6 months in 36 cases(69.2%), between 6 minths and 1 year in 5 cases(9.6%), between 1 and 2 years in 3 cases(5.8%), between 2 and 3 years in 2 cases(3.8%), and greater than 3 years in 6 cases(11.5%). 6. In distribution of the lesion sites, left was 93 cases(53.1%), right 80 cases(45.7%), and bilateral 2 cases(1.1%). 7. In degree of lung collapse, 17 cases(9.7%) were small(<20%), 127 cases(72.6%) moderate(20-40%), and 31 cases(17.7%) large(>40%). 8. The accompanied diseases of spontaneous pneumothorax were found in 17 cases, in which hydrothorax were 14 cases and homothorax were 3 cases. 9. The employed management were as follows; bed rest with oxygen inhalation in 6 cases(3.4%), thoracentesis in 4 cases(2.3%), closed thoracostomy in 136 cases(77.7%), and open thoracotomy in 29 cases(16.6%). 10. The reexpansion time after chest tube insertion was as follows; less than 1 day in 147 cases(89.6%), between 1 and 2 days in 12 cases(7.3%), between 2 days and 1 week in 4 cases(2.4%), and greater than 1 week in 1 case(0.6%). 11. The duration of chest tube insertion was as follows; less than 1 week in 102 cases(62.2%), between 1 and 2 weeks in 34 cases(20.7%), between 2 and 3 weeks in 14 cases(8.5%), between 3 and 4 weeks in 7 cases(4.3%), and greater than 4 weeks in 7 cases(4.3%). 12. The complications of closed thoracostomy were as follows; incomplete lung expansion in 4 cases and empyema in 1 case. 13. The indications of open thoracotomy were as follows; bleb or bullae on chest X-ray in 12 cases(14.4%), persistent air leak in 8 cases(27.6%), recurrent pneumothorax in 4 cases(13.8%), incomplete lung expansion in 3 cases(10.3%), and contralateral pneumothorax history in 2 cases(6.9%). 14. The duration of hospitalization was as follows; less than 1 week in 100 cases(57.1%), between 1 and 2 weeks in 29 cases(16.6%), between 2 and 3 weeks in 22 cases(12.6%), between 3 and 4 weeks in 9 cases(5.1%), and greater than 4 weeks in 15 cases(8.6%).

급성심근경색증의 조기진단에 있어서 Myoglobin의 진단적 의의

이정헌,김종근,정병천,서강석,박정배,조용근,류재근,전재은,채성철,박의현 大韓應急醫學會 1999 대한응급의학회지 Vol.10 No.2

Background: Exact and early diagnosis of acute myocardial infarction (AMI) is essential for the subsequent routine management of this frequent cardiovascular disease. Currently, AMI has been diagnosed using the combination of the history, electrocardiogram(ECG), and biochemical markers of myocardial necrosis. At present, many biochemical markers are used to diagnose AMI. In this study, the predictive values of serum myoglobin and creatine kinase-MB(CK-MB) were compared in the emergency department. Methods: Fifty-four consecutive patients who presented within 12 hours from onset of chest pain of presumed cardiac origin were enrolled into the study. Patients with trauma or renal failure were excluded. The serial serum myoglobin and CK-MB levels were obtained prospectively at admission and 2, 4, 6, 12, 24 and 48 hours after admission. We compare the levels of serum myoglobin and CK-MB within 2, 4, 6, 8, 10, 12, 24, and 48 hours after symptom onset respectively. And we compare the sensitivity, specificity, positive predictive value, and negative predictive value of myoglobin and CK-MB. Results: using World Health Organization criteria, 28 AMI patients were identified. Mean time from symptom onset to presentation was 4.1±1.3 hours. The predictive values of serum myoglobin were better than those of CK-MB within 6 hours after symptom onset. But, 6 hours after symptom onset, the predictive values of CK-MB were better than those of serum myoglobin. The false positive cases of serum myoglobin were 3-one was lung cancer with pleural effusion and the others were unstable angina. The false positive cases of CK-MB were 6-one case was viral myocarditis and the ohters were unstable angina. Conclusion: To compare the serum myoglobin and CK-MB in the diagnosis of AMI, serum myoglobin had better predictive values than CK-MB within 6 hours after symptom onset and useful in the early diagnosis of AMI. But, 6 hours after symptom onset, CK-MB had better predictive values than serum myoglobin and useful in following up.

Distribution of microorganisms isolated from respiratory organs and intestine of mice and rats

Jong Kun Seo,Mee Kyung Jang,Sun Bo Shim,Jin Ho Kang,Chang Jun Bae,Ji Soon Sin,Jong Min Woo,Su Hae Lee,Seung Wan Lee,Kab Ryong Chae,Chuel Kyu Kim 한국실험동물학회 2008 한국실험동물학회 학술발표대회 논문집 Vol.2008 No.-

Physicochemical Properties of Kefir

Jong-Ik Lee,Kwang-Young Song,Ji-Yeon Hyun,Chon-Jung Whan,Yun-Gyeong Kim,Jun-Ho Park,Soo-Kyeong Lee,Jae-Hoon Lee,Kun-Ho Seo 한국식품영양학회 2010 한국식품영양학회 학술대회논문집(학술심포지움) Vol.2010 No.12

Reactive oxygen species-based measurement of the dependence of the Coulomb nanoradiator effect on proton energy and atomic <i>Z</i> value

Seo, Seung-Jun,Jeon, Jae-Kun,Han, Sung-Mi,Kim, Jong-Ki Informa Healthcare 2017 International Journal of Radiation Biology Vol.93 No.11