고려 후기 얼자(孽子)의 지위 향상과 그 역사적 배경

이종서(Lee, Jong-seo) 한국역사연구회 2015 역사와 현실 Vol.- No.97

Examined in this article are the Seo’eol figures of the Goryeo period, who were also the former version of the Joseon Seo’eol figures. They were called as a whole as ‘Seo/Eol’ in Joseon, but in Goryeo there was a strict distinction between ‘Seo(庶)’ and ‘Eol(孼).’ In the early half of the Goryeo period, the latter(“Eolja” figures) were not allowed to be appointed to governmental positions, and the former(“Seoja” figures) were in some cases restricted from applying for the dynastic competitive examination and was not allowed to rise above certain level of posts inside the government. But coming into the second half of the Goryeo period, not only cases of Seoja figures but also those of Eolja figures, in which they were able to apply for the dynastic exam and rise to the highest level of posts inside the government, started to emerge. We can see such changes inside the royal family as well, as the Eolja sons of the king, who were formerly without any right to claim succession to the throne and were forced to become Buddhist priests, were now entitled to become governmental officials or receive honorary entitlements. We can see that from the case of King Gongmin-wang’s Eolja son Wang Wu, who was enthroned in 1374 as Gongmin-wang’s successor. Elevation in the Eolja figures’ status in the second half of the Goryeo period was enabled in the wake of the Yuan imperial government’s strong and steady influences and interventions into Goryeo internal affairs. At first, the Eolja figures mounted individual attempts and efforts to use the situation to their advantage. And when they grew sufficiently accustomed to the Yuan imperial order, their acknowledgement of the Yuan order, its law codes which were not without Chinese elements, and the Chinese nature of such behavioral protocols, all enabled them to accept the notion that Eolja figures deserve new chances and especially avenues of career advancement which were not available for them before. The Yuan law code which dictated and defined the status and rights of the ‘Seo(庶)’ figures literally granted the Seo and Eol figures in Goryeo the right to claim fiscal properties and career opportunities. The Goryeo leadership, including all the Confucian intellectuals, positively responded to the situation and recognized the Eolja figures’ political and social rights. Their status elevation did not involve anything abnormal or illegal, and even after Yuan lost its influences, they maintained such elevated status, which explain how the social status of the Seo/Eol figures in the early half of the Joseon period came to be established.

심혈관계 질환으로 관상질환 집중치료실에 입원한 환자들의 혜후 측정을 위한 APACHEⅢ점수 체계의 임상적 유용성

이공섭,이창선,최현주,홍종서,강지향,김도형,이민영,오인균,김병엽,김상억,김학찬,한승혜,이재용,지영우,안경주 대한순환기학회 2000 Korean Circulation Journal Vol.30 No.8

Production and Characterization of a Thermo-alkalotolerant Cyclodextrin Glucanotransferase from Thermo-alkalophilic Bacillus cereus B-13

Seo, Seung-Bo,Kim, Jae-Ho,Lee, Dae-Hyoung,Lee, Jong-Soo 배재대학교 자연과학연구소 2005 自然科學論文集 Vol.16 No.1

내열성의 cyclomaltodextrin glucanotransferase (CGTase)를 이용하여 열에 안정한 싸이클린 텍스트린 (CD)을 생산하기 위하여 매우 높은 CGTase 활성을 보이는 고열성이며 호알카리성인 B-13 세균을 분리하여 형태적, 생리학적 특성과 16S 리보솜 RNA 서열분석 등을 통하여 Bacillus cereus B-13으로 동정하였다. Bacillus cereus B-13을 2% 가용성 전분, 1% 효모 추출물, 1% Na_(2)CO_(3) 등을 함유하는 SYC 배지 (pH 8.5)에 접종하여 50℃에서 24시간 배양하였을 때 최고의 CGTase 활성(130 U/ml)을 보였다. 또한 부분 정제된 CGTase의 작용 최적 온도와 pH는 각각 65℃, pH 8.5-9.0 이었고 80℃이하와 pH 5.0-10.0에서 안정하였다. 1% 가용성 전분을 부분 정제한 CGTase와 작용 시켰을 때 49%의 CD 수율을 보였다. To produce a thermostable cyclodextrin by using thermotolerant cyclomaltodextrin glucanotransferase(CGTase), a thermophilic and alkalophilic bacterium isolate, designated B-13 showing the highest CGTase activity was isolated from natural sources and identified as Bacillus cereus B-13 based on the morphological and physiological characteristics, and 16S rRNA sequence. The maximal CGTase activity (130 U/ml) was obtained when Bacillus cereus B-13 was cultured in SYC medium containing 2.0% soluble starch, 1.0% yeast extracts, 1% corn steep liquor and 1% Na_(2)CO_(3) (pH 8.5) at 50℃ for 24 h and about 80% of maximal activity was also showed in the culture broth of 60℃ for 18 h . Optimum reaction temperature and pH of the partial purified CGTase for soluble starch were 65℃ and pH 8.5-9.0, respectively. The partial purified CGTase were also stable below 80℃ and pH 5.0-10.0. When 1% soluble starch was digested with the partial purified CGTase, the yield of cyclodextrin was 49%.

Bortezomib과 Dexamthasone으로 치료한 골수외 형질세포종 4예

백종현,이은영,장리라,손창배,신은경,서정아,이지숙,이호섭,이상민,신성훈,김양수 고신대학교의과대학 2007 고신대학교 의과대학 학술지 Vol.22 No.2

Despite the use of aggressive local and systemic treatment including autologous stem cell transplantation in multiple myeloma, extramedullary recurrences are common and the prognosis of these patients is poor. Many novel drugs such as thalidomide, lenalidomide and bortezomib improve the response of treatment of multiple myeloma, but some reports failed to describe thalidomide has effect in extramedullary plasmacytoma. Recent data report on the successful treatment plasmacytomas with bortezomib in patients with advanced multiple myeloma. We treated 4 relapsed or refractory extramedullary plasmacytomas with bortezomib at our institution. We recognized all these extramedullary plasmacytomas decreased and showed more than partial response. This report lends support to the efficacy of bortezomib in the treatment of plasmacytoma and describes the safe use of bortezomib. Responses may, however, be of short duration. Therefore, despite our limited experience, we propose that bortezomib may be considered a therapeutic option for such patients who have risk of radiation therapy

제대군인 취업지원 프로그램 구안

정철영,서우석,김성호,이예성,최동선,이종범,이성식,이건남,양안나,김성남 한국직업능력개발원 2007 직업능력개발연구 Vol.10 No.1

이 연구의 목적은 중·장기복무를 마치고 제대하여 재취업하고자 하는 제대군인들의 원활한 전직을 돕기 위한 제대군인 취업지원 프로그램의 개발방향과 개발안을 제시하는 데 있다. 이를 위해 국내·외에서 이루어지고 있는 제대군인 취업지원 프로그램의 실태를 분석하였고, 제대군인 취업지원 프로그램에 대한제대예정군인 및 제대군인과 기업체의 요구를 분석하여 시사점을 도출하였다. 그리고 이를 기초로 제대군인 취업지원 프로그램의 기본방향과 전체 흐름도, 세부 프로그램 개발안을 제시하였다. 이를 위해서 활용된 연구의 방법은 문헌연구, 조사연구, 전문가협의회 등이다. 이 연구를 통해서 제시된 제대군인 취업지원 프로그램의 개발방향과 개발안을 토대로, 일관되고 지속적인 수요자 중심의 제대군인 취업지원 프로그램의 개발이 가능할 것이다. The purpose of this study is to suggest plans and directions for developing. job-seeking support program for military veterans. The study is conducted through literature review, survey and interview. The results of this study are as follows: ⒧ basic development directions and flowchart of job-seeking support program for military veterans are suggested; and ⑵ development plans for sub-programs are suggested.

신경회로망을 이용한 터빈로타 디스크 키웨이의 결함 검출

이병우,이종오,윤운하,이병우,서원찬,이종규 한국비파괴검사학회 2003 한국비파괴검사학회지 Vol.23 No.1

최근 터빈 로타 디스크 키웨이에서 많은 응력부식균열이 발견되었으며, 터빈설비의 중대한 파손을 예방하기 위해 이러한 균열은 조기에 검출 및 평가되어야 한다. 본 연구에서는 초음파탐상의 RF(radio frequency) 신호를 역전파 알고리즘에 근거한 신경회로망에 적용하여 키웨이 주변의 균열에 대한 위치, 크기 및 방향성을 평가하였다. 각 반사영역에서 수신된 여러개의 피크로 나타나는 RF 신호를 각 반사영역에 대해 하나의 최대 피크를 가지도록 처리한 후, 트랜스듀서의 위치 정보와 각 반사파의 도달시간이 들어있는 주사 데이터를 작성하였다. 이 주사 데이터로부터 각 반사영역 사이의 시간차이와 트랜스듀서의 위치 정보를 신경회로망에 적용한 결과 키웨이에서 시작된 균열의 위치, 크기 및 방향성을 평가하는데 유용함을 알 수 있었다. A number of stress corrosion cracks in turbine rotor disk keyway in power plants have been found and the necessity has been raised to detect and evaluate the cracks prior to the catastrophic failure of turbine disk. By ultrasonic RF signal analysis and using a neural network based on back-propagation algorithm, we tried to evaluate the location, size and orientation of cracks around keyway. Because RF signals received from each reflector have a number of peaks, they were processed to have a single peak for each reflector. Using the processed RF signals, scan data that contain the information on the position of transducer and the arrival time of reflected waves from each reflector were obtained. The time difference between each reflector and the position of transducer extracted from the scan data were then applied to the back-propagation neural network. As a result, the neural network was found useful to evaluate the location, size and orientation of cracks initiated from keyway.

응급실 내원 환자의 만족도 평가 및 관련 요인에 대한 연구

서강석,감신,박정배,이정헌,김종근,윤영국,곽경숙,이원기,우석정 大韓應急醫學會 1998 대한응급의학회지 Vol.9 No.4

Background: To examine the influencing factors on patients' satisfaction in the emergency department(ED) for quality assurance. Methods: Patients who visited to the ED were prospectively investigated from November 1 to December 31, 1997. Authors developed questionnaire to investigate influencing factors on patients' satisfaction. A Chi-square test and LISREL 7.0 were applied for statistical analysis. Results: Patients' satisfaction was significantly related to physical environment variables, accessibility variables, kindness of hospital personnel variables, and patient's trust for doctors variables. In path analysis, willingness for revisit was influenced by patients' satisfation, accessibility, physical environment, patients' trust for doctors in order, and willingness for recommendation was influenced by accessibility, patients' satisfaction, and kindness of hospital personnel in order. Conclusions: The influencing factors on patients' satisfaction are physical environment, accessibility, kindness of hospital personnel, and patient's trust for doctors. Willingness for revisit and willingness for recommendation are influenced by patients' satisfation. In spite of some limitations, the results of this study can be used as a baseline information for exploring the influencing factors on patients' satisfaction. Further comprehensive research efforts should be made on the study of patients' satisfactoin in the ED.

천식 환자와 정상인에 있어서의 Extracellular Phospholipase A_2의 활성도

서영의,김능수,이종명 慶北大學校 醫科大學 1992 慶北醫大誌 Vol.33 No.3

Extracellular PLA_2는 arachidonic acid cascade에 작용하는 효소로서 다양한 세포들에서 분비되며, 염증반응을 비롯한 여러가지 질환에 관여함이 알려져있다. 저자들은 기관지 천식과 PLA_2의 관계를 알아보기 위해 천식 환자들과 정상 대조군의혈청과 소변에서 PLA_2 활성도를 측정하고 폐기능 악화에 따른 천식정도, 혈청 IgE치 및 말초혈액 호산구 수와의 관계를 조사하였다. 정상 대조군에 비하여 천식 환자군에서 혈청 및 소변의 PLA_2 활성도가 유의하게 증가되어 있었으나(P<0.01, p<0.05) 혈청 PLA_2 활성도는 폐기능 정도와는 비례하지 않았다. 또한 혈청 PLA_2 활성도와 혈청 IgE치나 말초 혈액 호산구 수 사이에는 상관관계가 없었다. 이상의 결과로 볼 때 PLA_2는 기관지 천식의 병리 기전에 관여할 것으로 사료되나 혈청 PLA_2 활성도가 천식정도를 반영하지는 않는 것으로 보여진다. Extracellular phospholipase A_2(PLA_2) is known to be secreted by the mononucteocytes, granukxytes and chondrocytes in the joint, and it is also reported that this enzyme is increased in inflammatory conditions, such as acute pancreatitis, sepsis, ARDS and arthritis. To evaluate the changes of PLA_2 in the asthmatics the authors measured extracellular PLA_2 of asthmatics and healthy individuals in their serum and urine. In 84 normal controls, the levels of PLA_2 activity in serum and urine were 177.26±130.68 U/㎖ and 127.56±87.04 U/㎖, respectively. There was significant difference between male and female groups in serum and urine. In 51 asthmatics, the levels of PLA_2 activity in serum and urine were 739.10±454.52 U/㎖ and 292.50±154.49 U/㎖, respectively. These were significantly higher than those of healthy controls in both serum and urine. No significant correlation was found between serum PLA_2 activity and peripheral blood eosinophil count and there was no significant difference in serum PLA_2 activity between symptomatic asthmatics and asymptomatic asthmatics. However the level of serum PLA_2 activity in asymptomatic asthmatics was still higher than that of healthy controls. Receiving steroids seems to make no difference in serum PLA_2 activity in asymptomatic asthmatics.

Amylase가 Hydroxyapatite 탈회에 미치는 영향

서정택,이인환,최병재,이종갑 大韓小兒齒科學會 1998 大韓小兒齒科學會誌 Vol.25 No.2

Salivary proteins which are produced in the saliary acinar cells have been known to be involved in the Calcium and phosphate metabolism. The acquired pellicle resulting from such metabolism is considered as a secondary defence membrane against tooth caries. In this respect, some proteins included in saliva probably play an important role in the prevention of demineralization in enamel. On the other hand, fluoride has long been known to prevent the demineralization of enamel by the inhibition of the growth of Streptococcus mutans (S.mutans) and by the chemical reaction with calcium and phosphate. therefore, I have examined the roles of amylase and albumin in the demineralization of enamel and compared these preteins with fluoride in terms of anticariogenic effect. 1. The demineralization caused by S. mutans occurred slowly and progressively for the first 60 min, then the rate of demineralization was accelerated afterwards. 2. pH decreased continuously during the entire period of each experiment. 3. the demineralization was significantly inhibited by the preteatment of amylase and fluoride but albumin had little effect on it. 4. An addition of 0.1 mM lactic acid (final concentration 0.1μM) caused a rapid increase in calcium concentration reaching a mazimum within 10 min. 5. pH decreased rapidly by the addition of 0.1mM lactic acid and reached a minimum within a few seconds followed by an increase in pH. pH reaced a plateu with 10 min. 6. Fluoride, amylase and albumin played little role in the 0.1 mM lactic acid-induced demineralization. 7. A slow infusion of 0.1 M lactic acid at a rate of 5 ㎕/min caused a slower increased I calcium concentration compared with the bolus addition of lactic acid. 8. Fluoride had an inhibitory effect on the calcium release caused by slow infusion of lactic acid while amylase and albumin had no effect on it. These results suggest that fluoride inhibits demineralization by protecting the HA from the acid attack whereas amylase has a direct effect on S. mutans to prevent demineralization.

실기종목에 따른 중학교 체육수업의 실제 학습시간 비교

서봉한,황영성,이종현,오영도,이중숙 釜山大學校 附設 體育科學硏究所 1998 體育科學硏究所 論文集 Vol.14 No.-

The purpose of this study is to investigate the academic learning time of basketball, valleyball, vault horse, and balance beam teaching in physical education of junior high school. The subjects were 16 junior high school students living in U city, and their classes were recorded on video tape. The analatic methods were 5 seconds observation with BESTPED system, monitor stop and recording survey of Academic Learning Time-Physical Education. To analyze the academic learning time, independent varieables was set to practical carriculum(basketball, valleyball, vault horse, and balance beam) and dependent varieables were set to the academic learning time. To testify the relation between the independent varieables and the dependent varieables, dependent t-test was accomplished ar α=.05 level. The results were as follows; 1. In the comparison of ball game with gymnastics, position movement(p=.0004), practice(p=.0023), implement preparation(p=.0001), exercise(p=.000) and deviation(p=.000) brought out the differences. Also, waiting(p=.0001), watching(p=.0037) and information transmission(p=.0157) brought out the differences too, but information reception and interaction didn't. 2. In the comparison of basketball, position movement(p=.0438), practice(p=.0012), exercise(p=.0012) brought out the defferences but implement preparation didn't. Also, information reception(p=.0001), interaction(p=.0049), information transmission(p=.0000) and waiting(p=.0377) brought out the differences too, but watching didn't. 3. In the comparison of vault horse with a balance beam, practice(p=.0230) and exercise(p=.0003) brought out the differences but position movement, implement preparation, and deviation didn't. Also, information reception(p=.0013) and waiting(p=.0013) brought out the differences too, but interaction, information and watching didn't.