한국 정신장애의 역학 조사 연구[I] : 각 정신장애의 유병률

조맹제,함봉진,김장규,박강규,정은기,서동우,김선욱,조성진,이준영,홍진표,최용성,박종익,이동우,이기철,배재남,신정호,정인원,박종한,배안,이충경 大韓神經精神醫學會 2004 신경정신의학 Vol.43 No.4

Objectives : This study aims to estimate the prevalence of the DSM-IV psychiatric disorders in Korean population using the Korean version of Composite International Diagnostic Interview (K-CIDI). Methods : Subjects were selected by taking multi-stage, cluster samples of 7,867 adult household residents, 18 to 64 years of age, in ten catchment areas. Total 78 trained interviewers administered the K-CIDI to the selected respondents, from June 1 to November30,2001. Results : Total 6,275 respondents completed the interview. Some 33.5% of respondents reported at least one lifetime disorder, 20.6% reported at least one-year disorder, and 16.7% reported at least one-month disorder. The most common lifetime disorders were alcohol abuse/dependence (17.24%), nicotine dependence/withdrawal (11.19%), specific phobia (5.16%), and major de-pressive disorder (4.25%). The lifetime prevalence of substance abuse/dependence (0.25%) and schizophrenia (0.16%) was very low. Nicotine and alcohol use disorder showed very high male/female ratio. Mood disorder and anxiety disorder were more prevalent among female than male. Conclusion : The prevalence of psychiatric disorders was high. In comparison with other studies, remarkable differences in distributions of psychiatric disorders across the areas and times were observed.

대전시 유통 과실류의 농약 잔류 실태 및 위해성 평가

한국탁,박혜진,이규승,김일중,김규섭,조성민 한국환경농학회 2002 한국환경농학회지 Vol.21 No.4

대전시 노은 도매 시장에 서 채취한 과실류와 6종의 농약잔류량을 조사한 후 이에 대한 위해성 평가를 실시하였다. 전체 120건 분석시료 중 70.8%가 농약 성분이 검출되었고 그중 1.67%가 잔류허용기준치을 초과하여 검출되었다. 검출 비율이 높은 시료는 사과, 복숭아, 포도 등이었다. 검출된 성분에서 살충제는 유기인계, 합성 pyrethroid계, 유기염소계가 비슷한 비율로 검출되었고, 살균제에서는 특히 procymidone(dicarboximide계)과 chlorothalonil(유기염소계)의 검출비율이 높았다. 검출빈도가 높은 성분은 chlorothalonil, chlorpyrifos, fenvalerate, procymidone, deltamethrin, EPN의 순이었다. 위해성을 평가하기 위해서 각 농작물에 대한 농약의 추정섭취량과 ADI를 비교한 결과, 추정섭취량의 비율이 1.221%이하로 나타나 그 영향이 매우 낮은 것으로 판단되었다. 이것은 농약 잔류 허용기준치를 초과한 농작물인 복숭아에서 chlorothalonil, EPN에 대해서도 동일한 결과를 나타내었다. Pesticide residues in some fruits collected at Noeun wholesale market, Daejeon were surveyed and assessed its risk. In 120 samples, the detection rate of pesticide was 70.8% and the rate exceed MRL was 1.67%. Highly detection rate of commodities was apple, peach and grape. Organophosphorus, organochlorine and pyrethroid insecticide were found with similar rate relatively, but most of fungicides were procymidone(dicarboximides) and chlorothalonil(organochlorine). The order of detected pesticide were chlorothalonil, chlorpyrifos, fenvalerate, procymidone, deltamethrin and EPN. In order to assess risk, estimated intake amount of each pesticide was compared to ADI. Although some peach were exceed MRL, the total amount and uptake pesticides was less than 1.22% comparing to ADI.

사람 갑상선자극호르몬 수용체를 발현하는 Chinese Hamster Ovary(hTSHR-CHO)세포를 이용한 자극형 갑상선자극호르몬 수용체 항체 활성 측정의 임상적 유용성

한희정,원진호,채수홍,김현진,송민호,김영건,노흥규 충남대학교 의과대학 지역사회의학연구소 2000 충남의대잡지 Vol.27 No.1

Detection of thyroid stimulating hormone receptor(TSHR) autoantibodies has clinical value in establishing the diagnosis of Graves ' disease, and in predicting its clinical course with high sensitivity and high specificity. Especially, TBII using radioreceptor assay has been widely used. Recently, for detecting thyroid stimulating antibody(TSAb), a sensitive method using human TSH receptor-transfected Chinese Hamster Ovary(CHO) cells has been developed and clinically used. The aims of this study are to determine the change and discrepancy of 2 TSHR autoantibodics in clinical course and to evaluate the correlation between 2 autoantibodies. We measured TSAb and TBII in 30 newly diagnosed and untreated patients and in 73 previously diagnosed as Graves ' disease and treated with antithyroid drug. Also we compared the changes of the antibodies in clinical course and correlation between 2 antibodies. Thes results are summarized follows. 1. In newly diagnosed patients, all of the 30 patients had positive TBII and/or TSAb. None of them had negative TBII and negative TSAb. And in newly diagnosed patients, mean TBII and mean TSAb values are 46.8% and 361%, respectively. In 73 treated patients mean values are 18. 7% and 196% each other. Therefore, newly diagnosed group has significant greater TBII and TSAb than antithyroid drug-treated group. 2. TBII was significantly different between euthyroid group and thyrotoxic group in antithyroid drug-treated patients, but TSAb was not. 3. TBII was sequentially decreased as increased medication duration, but TSAb was not shown sequential decrease as increased medication duration. 4. There was significant negative correlation between cumulative doses of antithyroid drug and TBII, but no significant correlation between cumulative doses and TSAb. 6. There was significant positive correlation between TBII and TSAb in total patients group and in antithyroid drug medication group, but not in newly diagnosed group. In conclusion, in Graves ' disease patients, detection of TSHR antibodies are clinical values in establishing the diagnosis and prediction of clinical course. A method detecting TSAb using hTSHR-CHO cells should be further studied for standardization of measurement, and for detecting the changes of TSAb in clinical course, long-term follow-up of patients are important.

페놀이 메탄 발생속도에 미치는 영향

한규원,조영일,현영진 연세대학교 산업기술연구소 1981 논문집 Vol.13 No.2

Chemicals such as phenol inhibit the microbial metabolism. In this study, the effect of phenol on the methane generation and yield during anaerobic fermentation of organic synthetic wastewater was investigated. Experimental results obtained by changing the phenol concentration showed that the gas yield was decreased as the inhibitor concentration was increased. Methane generation rate was found to be expressed by a Monod-type equation in which a inhition factor was introduced as a function of the phenol concentration.

會計分野에 있어 專門家시스템의 硏究開發動向 및 發展展望

韓振洙,朴廂圭 동국대학교 경영대학원 1992 經營論叢-東國大學校 經營大學院 Vol.16 No.-

모터사이클 엔진실린더의 호닝가공용 혼스톤에 관한 연구

한규택,장명진 釜慶大學校 1999 釜慶大學校 論文集 Vol.4 No.1

Grinding technology in modern industry society is focusing on research and development for grinding stone and mashining parts for the purpose of high accuracy and high efficiency of products. But, in order to equip the high technology and high accuracy of micro stone which is one of grinding stone, a continuous effort on R & D is required. In this study, the honing processing work of 2 cycle engine cylinder for motorcycle which has an open hole is carried out so as to investigate the boring and hone stone effects on accuracy of honing. As the experimental result of this study, we could conclude that it is possible to secure good conditions of honing by controlling and keeping appropriate cycle-time in the stage of boring for the prior step of honing.

열린 홀을 가진 2사이클 엔진실린더의 호닝가공시 호닝의 정밀도에 미치는 혼스톤의 영향

한규택,장명진 韓國工作機械學會 2000 한국생산제조학회지 Vol.9 No.3

Grinding technology in morden industry society is focusing on research and development for grinding stone and machin-ing parts for the purpose of high accuracy and high efficiency of products. But, in order to equip the high technology and high accuracy of micro stone which is one of grinding stone, a continuous effort on R & D is required. In this study, the honing processing work of 2 cycle engine cylinder for motorcycle which has an open hole is carried out so as to investigate the boring and hone stone effects on accuracy of honing. As the experimental result of this study, we could conclude that it is possible to secure good conditions of honing by controlling and keeping appropriate cycle-time in the stage of boring for the prior step of honing,

슬러지 전처리와 고농도 MBR을 이용한 슬러지 감량화 공정연구

한규철,염익태,정우진,김형수 대한상하수도학회 2003 상하수도학회지 Vol.17 No.4

From this research, the performances of a sludge reduction in the sewage sludge aerobic digestion was experimented by using a sludge pretreatment and membrane bioreactor. The submerged plate membrane was used as the solid-liquid separation membrane . After drawing small amounts of sludge in a bioreactor and then doing the alkaline treatment and ozone treatment, the sludge was sent to back to the reactor. The HRT in the reactor was set as 5 days and the operation in the reactor was carried out at the DO of 1㎎/L on average. After 100 days of operation in the reactor, it was shown that the reduction efficiency of total solids was more than 83%. Most of volatile solids were removed through mineralization, and the considerable portion of the nonvolatile solids was dissolved and then flowed out with the effluent. Only about 16.3% of total solids in the sludge was accmulated in the reactor even without the loss of volatile fraction. Also, by deriving nitrification and denitrification in one reactor simultaneously, more than 90% of nitrogen removal effect was realized and the experiment was run smoothly without fouling of membrane, even in the high concentration of MLSS. Based on this experiment. sludge can be reduced considerably at a low HRT by these two newly suggested approach.

간호사의 정신과 자문에 대한 기대도

韓辰熙,房勝規,金光壽,柳太烈 최신의학사 1991 最新醫學 Vol.34 No.1

한국 병원건축의 발전과정에 관한 연구(1) : 서울대학교 병원의 조직 및 기능변화와 시설의 배치변화를 중심으로 Focus on the changes of the hospital organization, function and arrangement of Seoul National University Hospital

한진규,이특구 한국의료복지시설학회 2005 의료·복지 건축 Vol.11 No.1

This study presents how Seoul National University Hospital, one of the representative hospitals in Korea, has been developed and changed from the opening to the present. It tried to find a trend in Korea hospital development through the investigation of Seoul National University Hospital, with the purpose of presenting a basic source of reference to hospital architecture planning.