가감청영탕(加減淸營湯)에 효과를 보인 열성 아토피 피부염 환자 6례 증례 보고

서지혜,정창환,박선정,임소영,한수련,Seo, Ji-Hye,Jung, Chang?Hwan,Park, Seon-Jeong,Lim, So-Young,Han, Su-Ryun 대한한방안이비인후피부과학회 2014 한방안이비인후피부과학회지 Vol.27 No.3

Objective : The purpose of this study is to investigate the effect of Gagamchengyoung-tang($Ji\bar{a}ji\check{a}nq\bar{i}ngy\acute{i}ng-t\bar{a}ng$) for atopic dermatitis patients diagnosed as the febrile tendency. Method : This case study was done on 6 atopic patients with febrile tendency who have visited Korean Medicine Clinic from 2013.08.01. to 2014.04.30.. Gagamchengyoung-tang($Ji\bar{a}ji\check{a}nq\bar{i}ngy\acute{i}ng-t\bar{a}ng$) was prescribed to all 6 patients and evaluated the symptom change through photographs and questionnaire. Objective SCORAD Index(OSI) was used to evaluate the objective symptom and VAS was used to evaluate the subjective change. Results & Conclusion : The Objective SCORAD index and VAS were decreased in all patients. The average OSI reduction score was 26.3. Most symptoms of 6 patients were improved. Gagamchengyoung-tang ($Ji\bar{a}ji\check{a}nq\bar{i}ngy\acute{i}ng-t\bar{a}ng$) can be effective in patients who were diagnosed as febrile tendency.

3,4‑Dichloroaniline promotes fatty liver in zebrafish larvae

Ji‑Seon Park,송정아,Jong‑Su Park,이상우,Jieon Lee,Han‑Jin Park,Woo‑Keun Kim,Seokjoo Yoon,Hang‑Suk Chun 대한독성 유전단백체 학회 2020 Molecular & cellular toxicology Vol.16 No.2

Backgrounds 3,4-Dichloroaniline (3,4-DCA) is a transformation product of herbicides that is commonly used as a reference in developmental toxicity studies (OECD TG 236) (Bonnet et al. in Environ Toxicol 22:78–91, 2007). However, the mechanisms underlying 3,4-DCA-induced hepatotoxicity are not well known. Methods We exposed zebrafish larvae at 72 hpf to 3,4-DCA for 3 days and observed lipid accumulation in liver treated with 10-μM 3,4-DCA using oil red O staining. Subsequently, we performed qRT-PCR analysis to determine the genes involved in the observed lipid accumulation. Results We found that genes related to lipogenesis (srebp1, pparγ, lipin1, and scd1) and ER stress (bip, atf4, ddit3, dnajc3, and edem1) were significantly upregulated. In addition, we found that ROS generation increased in the larvae treated with 10-μM 3,4-DCA. Moreover, glutathione-S-transferase activity in these larvae was increased by 3,4-DCA in a dose-dependent manner, and the expression of the inflammation marker il-1β increased. Conclusion Our results indicated that exposure to 3,4-DCA induced fatty liver in zebrafish larvae and that this, in association with additional factors such as ER stress response, can promote liver damage. We accordingly suggest that 3,4-DCA could be used to induce fatty liver in zebrafish larvae.

Acaricidal toxicities and synergistic activities of Salvia lavandulifolia oil constituents against Dermatophagoides farinae, D. pteronyssinus, and Tyrophagus putrescentiae

Seon?A Choi,Won-Seok Lee,Yun-Seon Yu,Myung-Ji Lee,Hoi-Seon Lee 한국농약과학회 2018 한국농약과학회 학술발표대회 논문집 Vol.2018 No.4

Influence of Gas Nitriding on the Damping Capacity of Fe‑17Mn Alloy

Seon‑Min Choi,Ji‑Sook Park,Kyongjun An,이영국 대한금속·재료학회 2019 METALS AND MATERIALS International Vol.25 No.1

Fe-17Mn alloy has been attracted as a high damping alloy due to its excellent damping capacity and tensile properties. For itsindustrial application, it is necessary to improve both wear resistance and anti-oxidation. To solve this problem, gas nitridingwas performed at 520 °C for 10 h using cold-rolled specimens. The nitrided specimen revealed a thick nitride layer of~ 68 μm with ~ 20%Mn and a hardness value of ~ 650 Hv on the matrix of ε martensite and γ austenite without the diffusionlayer. The damping capacity of the nitrided specimen was decreased with increasing the thickness ratio of nitride layer tomatrix. However, when the thickness ratio was ≤ 1.5%, the damping capacity of the nitrided specimen was similar to that ofthe nitride-free specimen. This indicates that the wear resistance and anti-oxidation of Fe-17Mn alloy can be improved bya thin nitride layer without the loss of its damping capacity.

연결어미 ‘-든지’의 통사 · 의미적 특징

목지선(Mok, Ji-seon) 한국어문학회 2017 語文學 Vol.0 No.136

The ending ‘-deunji’ is divided into single construction and reduplication construction based on the number of proposition combined. It may be used as a final ending, connective ending, or ending of embedded sentence in terms of the presence or types of following elements. This study examines various usage of ‘-deunji’ particularly in a form of the reduplication construction such as ‘-deunji, -deunji’ and analyzes its syntactic and semantic characteristics. First, the primary condition of using ‘-deunji’ is the availability of the list of items for selection, and therefore the ending does not merely require the performance of selection. This may be supported by the fact that ‘-deunji’ is often employed in the reduplication construction to represent the meaninglessness of selection, and that it also appears in a form of ‘infinitival construction + -deunji.’ On the other hand, the form of ‘proposition + -deunji’ contains a semantic feature so that it can be repeated as ‘ending 1, ending 2, ....., ending n + following phrase,’ when the range or standard of selection is decided by the characteristics of the following phrase. However, it is difficult to conclude that the preceding endings merely function to enumerate items, while the last ‘ending n’ has a distinct function. According to this study, the reduplication construction of ‘-deunji, –deunji’ can be divided into ‘-deunji -deunji + following phrase’ and ‘-deunji -deunji + hada.’ First of all, the form of ‘-deunji -deunji + following phrase’ can be sub-categorized in accordance with the presence of the expression that characterizes the listed objects in the following phrase. In the form where the reduplication construction of ‘-deunji’ is followed by the phrase, the necessity of selection varies depending on the proposition in the phrase. The use of the form depends on the necessity of selection, and the form can be distinguished by the way in which the followed expression imposes limitation on the ‘-deunji’ phrase. In this respect, this article argues that ‘-deunji -deunji + following phrase’ has three types in regard to the openness of proposition list and the necessity of selection: extreme openness, semi-openness, and closeness. The first type is conditioned by the complete absence of the following phrase expression that intends to define the category or characteristics of the listed proposition. In this case, the reliability of the former “deunji” statement does not affect the meaning of following phrase, and other objects can be listed as many as the speaker wants, so it shows the extreme openness. The second type is used when the expression that defines the category or selection criteria of listed propositions is followed by the phrase that contains semi-openness in the followed expression. This type can be divided again based on whether or not the followed phrase or noun (phrase) presents the selection criteria that characterizes the listed objects. The latter pattern is often used when the speaker only intends to provide a list of objects. Lastly, the third type is the expression that put a limit on the number of listed propositions and selections in the following phrase, and it therefore represents the closeness of listed objects. Therefore, the pattern of extreme openness does not demand the listener’s act of selection, while that of semi-openness and closeness requires the performance of selection.

광주광역시 치매의 유병률과 위험인자의 도시-농촌 지역 비교

신일선,김재민,윤진상,김석재,양수진,김웅장,이승현,강순아,곽지영,이형영 大韓神經精神醫學會 2002 신경정신의학 Vol.41 No.6

연구목적 : 본 연구의 목적은 광주광역시의 도시 및 농촌 지역에 거주하는 노인에서 치매의 유병률과 위험인자를 조사하고자 하였다. 부가적으로 이 두 지역간에 치매의 유병률과 위험인자를 비교하고자 하였다. 방 법 : 광주광역시의 전형적인 도시와 농촌지역의 65세 이상의 노인(N=1,598)을 대상으로, 2단계의 역학연구를 수행하였다. 1차 선별 단계에서는 38명의 훈련된 연구보조원이 대상노인을 면담하여, 사회인구학적 특징을 조사하고 한국판 간이정신상태검사(Korean version of Mini-Mental State Examination ; MMSE-K)로 평가하였다. 2차 임상 진단 단계에서는 1차 단계에서 MMSE-K 점수가 24점 이하인 노인(N=431)을 대상으로, 전문연구팀의 임상적 평가를 통해 치매를 진단하고 원인질환별로 알쯔하이머병(Alzheimer's disease ; AD), 혈관성 치매(vascular dementia ; VaD) 및 기타 치매로 분류하였다. 대상노인에서 치매의 유병률을 측정한 후, 광주광역시 전체 노인의 연령보정 유병률을 산출하였다. 전체 대상에서 AD의 위험인자를 조사한 후, 도시와 농촌군으로 나누어 분석을 다시 시행하였다. 결 과 : 1차 및 2차 단계의 참가율은 각각 71.0%(N=1,134) 및 83.2%(N=410) 였다. 연구 참여 노인(N=1,134)에서 전체 치매, AD 및 VaD의 유병률은 최소 각각 9.7%, 5.2%, 1.8%였다. 광주광역시 전체 노인의 연령 보정 유병률은 각각 10.7%, 5.7%, 1.9%인 것으로 산출되었다. AD의 독립 위험인자는 고령, 여성, 무학이었다. 도시와 농촌에 따른 유병률의 차이는 파악되지 않았다. 그러나 AD의 위험인자는 지역에 따라 차이가 있었다. 도시 노인에게는 무학만이, 농촌 노인에게는 고령과 여성인 경우가 독립 위험인자였다. 결 론 : 광주광역시 노인에서 치매의 유병률은 높았고, 이는 국내 다른 지역에서 수행된 선행연구 결과와 유사하였다. 알쯔하이머형 치매의 위험인자는 도시와 농촌에 따라 다른 결과를 보였다. 본 연구 결과는 한국에서의 치매의 실태를 반영하며, 치매의 적절한 관리와 예방을 위해서는 지역성 특성이 고려되어야 함을 시사한다. Objectives : The purpose of this study was to investigate the prevalence rate and risk factors of dementia in an urban and a rural sample of older persons in the metropolitan Kwangju area, Republic of Korea. In addition, the prevalence rate and risk factors of dementia between the two samples were compared. Methods : A two-phase epidemiological study of residents aged 65 or over(N=1,598) was conducted in a highly developed, urban and a non-contiguous, poorly developed, rural area of metropolitan Kwangju. In the first(screening) phase, 38 trained research assistants collectively peformed in-home interviews for all participants. Detailed sociodemographic characteristics were gathered and the Korean version of Mini-Mental State Examination (MMSE-K) was administered. In the second (diagnosing) phase, diagnosis of dementia was established for those scoring 24 or less on the MMSE-K in the screening phase(N=431), and etiological types of dementia were classified to Alzheimer's disease(AD), vascular dementia(VaD) or miscellanous type by two teams of experts. Prevalence rate of dementia was determined in the participants, and age-standardized prevalence rate adjusted by age distribution in metropolitan Kwangju was estimated. For AD, the risk factors were investigated in all participants, and analyses were repeated for the urban and rural samples separately. Results : The participating rates in the first and second phases were 71.0%(N=1,134) and 83.2%(N=410), respectively. In the participants, the prevalence rates of dementia(all types), AD and VaD were 9.7%, 5.2% and 1.8%, respectively. The age-standardized prevalence rates were 10.7%, 5.7% and 1.9%, respectively. Aging, female gender and no education(complete lack of formal education) were identified as independent risk factors for AD. No difference between the urban and rural samples was observed in the prevalence rates of dementia(all types), AD and YaD. However, risk factors for AD differed between these areas. In the urban sample, no education was the only significant factor ; whereas, aging and female gender were identified as risk factors in the rural sample. Conclusion : A high prevalence rate of dementia was observed among old persons in metropolitan Kwangju, consistent with previous studies conducted in other Korean areas. The risk factor profi1es for AD differed between urban and rural settings. The results of this study reflect the current status of dementia in Korea and suggests that appropriate management and prevention strategies for dementia should be tailored toward the geographic settings.

유럽연합과 프랑스의 미디어교육 공교육화 준비 현황분석 : 문화기호학적 방법론을 중심으로

박지선 경북대학교 사범대학부속 중등교육연구소 2006 중등교육연구 Vol.54 No.2

건강한 성인에서 발병한 칸디다와 연관된 위궤양 1례

박지훈,이상혁,김희,이재호,박성재,지삼룡,양성연,박은택,이연재,설상영,정정명,강미선 白中央醫療院 2005 仁濟醫學 Vol.26 No.1

Fungus such as Candida albicans is a normal flora that is frequently found in the oral cavity, gastrointestinal tract, genitourinary tract, vaginal mucosa in a normal person. However, candida can cause opportunistic infection in an immune compromised host. Candidiasis has broad spectrum of disease from mucocutaneous infection to invasive or disseminated infection. But, it is rarely reported that candida is associaed with gastrointestinal tract disease in a healthy adult. The case of gastric ulcer associated with candida particularly in a health adult is reported with relevant literature.

CRM 활동이 관계편익, 관계몰입 및 행동의도에 미치는 영향 : 미용산업을 중심으로

성현선,정지선 동양대학교 2010 동양대학교 논문집 Vol.14 No.1

The study examines the influences of CRM activites to the relational benefits, relational commitment and behavioral intention. First of all, CRM activities were classified into 3 categories using factor analysis: continuous contact, discriminated management, typical compensation. Or Relational benefits were classified into 3 categories: social benefits, customization benefits, economic benefits. To analyze the data, with SPSS program (Ver.12.0) and AMOS program (Ver.5.5). The result of fators analysis, only discriminated management have a positive effect with continuous contact, discriminated management and typical compensation. Second, continuous contact, discriminated management and typical compensation have a positive with relational commitment. Furthermore all benefits have a positive with behavioral intention.

내측연수경색에서 관찰된 안구의 반대편 측방돌진

김지수,문소영,정선미,한문구,박성호 대한평형의학회 2003 Research in Vestibular Science Vol.2 No.2