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Root-Zone Heating Improves Growth and Development of Cyclamen persicum under Low Air Temperature
Ji Hum Park,Wook Oh,Hyun Ki Kim,Yong Ha Rhiet,Changhoo Chun,Ki Sun Kim 한국원예학회 2007 Horticulture, Environment, and Biotechnology Vol.48 No.2
This study was conducted to examine the effect of root-zone temperature (RZT) on growth and development of cyclamen (Cyclamen persicum cv. Metis Scarlet Red) under low air temperature regime for energy saving. Cyclamen plants with 6-7 unfolded leaves were exposed to RZT 12, 16, 20, or 24°C in a constant 12°C room equipped with floating hydroponic and nutrient-stagnant wick culture systems. Root-zone heating promoted growth, showing the maximum dry weight at 20°C. The number of leaves and visible buds (VB) at harvest increased as RZT increased from 12 to 20°C, but slightly decreased from 20 to 24°C. Root-zone heating promoted photosynthesis and hastened leaf unfolding and VB emergence. RZT of 20°C increased root activity as compared with that of 12°C, although there was no difference in leaf width and root length. Most favorable RZT for growth and development of cyclamen under low air temperature was 20°C. Therefore, root-zone heating improved growth and development in ‘Metis Scarlet Red’ cyclamen under low air temperature for saving heating energy.
Min Ji Cho,Ji Hyun Kim,Chan Hum Park,Ah Young Lee,Yu Su Shin,Jeong Hoon Lee,Chun Geun Park,Eun Ju Cho 대한지역사회영양학회 2018 Nutrition Research and Practice Vol.12 No.3
BACKGROUD/OBJECTIVES: Neuroinflammation plays critical role in neurodegenerative disorders, such as Alzheimer’s disease (AD). We investigated the effect of three licorice varieties, Glycyrhiza uralensis, G. glabra, and Shinwongam (SW) on a mouse model of inflammation-induced memory and cognitive deficit. MATERIALS/METHODS: C57BL/6 mice were injected with lipopolysaccharide (LPS; 2.5 ㎎/㎏, intraperitoneally) and orally administrated G. uralensis, G. glabra, and SW extract (150 ㎎/㎏/day). SW, a new species of licorice in Korea, was combined with G. uralensis and G. glabra. Behavioral tests, including the T-maze, novel object recognition and Morris water maze, were carried out to assess learning and memory. In addition, the expressions of inflammation-related proteins in brain tissue were measured by western blotting. RESULTS: There was a significant decrease in spatial and objective recognition memory in LPS-induced cognitive impairment group, as measured by the T-maze and novel object recognition test; however, the administration of licorice ameliorated these deficits. In addition, licorice-treated groups exhibited improved learning and memory ability in the Morris water maze. Furthermore, LPS-injected mice had up-regulated pro-inflammatory proteins, such as inducible nitric oxide synthase (iNOS), cyclooxygenase-2, interleukin-6, via activation of toll like receptor 4 (TLR4) and nuclear factor-kappa B (NFκB) pathways in the brain. However, these were attenuated by following administration of the three licorice varieties. Interestingly, the SW-administered group showed greater inhibition of iNOS and TLR4 when compared with the other licorice varieties. Furthermore, there was a significant increase in the expression of brain-derived neurotrophic factor (BDNF) in the brain of LPS-induced cognitively impaired mice that were administered licorice, with the greatest effect following SW treatment. CONCLUSIONS: The three licorice varieties ameliorated the inflammation-induced cognitive dysfunction by down-regulating inflammatory proteins and up-regulating BDNF. These results suggest that licorice, in particular SW, could be potential therapeutic agents against cognitive impairment.
Kim, So-Seob,Kim, Ji-Sun,Park, Hum-Dae,Lee, Su-Kap,Park, Il-Kun,Lee, Dong-Won,Kim, Yun-Sik,Park, Yong-Su,Kim, Jae-Young,Park, Min-Chul,Oh, Dae-Sik,Kim, Jae-Myeoung 韓國受精卵移植學會 2008 한국동물생명공학회지 Vol.23 No.4
We separately cultured follicular oocytes collected from individual ovaries of slaughtered Korean native cows and examined both the embryonic development rate and pregnancy rate after embryo transplantation according to the meat yield and quality grades of the source beef carcass. Oocytes from meat yield grade B cows exhibited a higher fertilization rate and embryonic developmental rate to the eight-cell stage than oocytes from grade A or C animals (p<0.05), but there was no significant difference in rate of development to the blastocyst stage among meat yield grades A, Band C. The oocyte cleavage rate and development rate to the eight-cell stage from meat quality grade 3 cattle was higher than grades 1++, 1+, 1 and 2 (p<0.05). Embryos derived from grade animals displayed a development rate to the blastocyst stage of 19.4%, which was also higher than all other meat quality grades (p<0.05). Transplantation of in vitro-cultured oocytes from meat yield grade A ovaries led to a higher pregnancy rate (64.2%) than in vitro-cultured oocytes from meat yield grade B ovaries (56.5%), but there was no significant difference between the two groups in pregnancy or abortion rates. In conclusion, embryonic development rate and pregnancy rate has a close relation to meat quality grades of the source beef carcass, this results is to give information for the Korean native cows improvement of breed.
Park, Chan Hum,Lee, Ah Young,Kim, Ji Hyun,Seong, Su Hui,Cho, Eun Ju,Choi, Jae Sue,Kim, Min Jo,Yang, Siyoung,Yokozawa, Takako,Shin, Yu Su World Scientific Publishing Company 2019 The American journal of Chinese medicine Vol.47 No.2
<P>This study examined whether serotonin and two of its derivatives, <TEX>$ N$</TEX>-feruloylserotonin and <TEX>$ N$</TEX>-(<TEX>$ p$</TEX>-coumaroyl) serotonin, have a renoprotective effect in a mouse model of cisplatin-induced acute renal failure. Cisplatin (20<TEX>$ \,$</TEX>mg/kg body weight) was administered by intraperitoneal injection to male BALB/c mice that had received oral serotonin, <TEX>$ N$</TEX>-feruloylserotonin or <TEX>$ N$</TEX>-(<TEX>$ p$</TEX>-coumaroyl) serotonin (7.5<TEX>$ \,$</TEX>mg/kg body weight per day) during the preceding 2 days. At 3 days after the cisplatin injection, serum and renal biochemical factors, oxidative stress, inflammation and apoptosis-related protein expression were evaluated, and histological examinations were performed. Cisplatin caused reduction in body weight and an increase in kidney weight; however, <TEX>$ N$</TEX>-(<TEX>$ p$</TEX>-coumaroyl) serotonin and <TEX>$ N$</TEX>-feruloylserotonin attenuated these effects. Moreover, the serotonin derivatives significantly decreased serum urea nitrogen and creatinine levels. They also significantly reduced the level of reactive oxygen species and upregulated the expression of glutathione peroxidase in the kidney. Furthermore, the serotonin derivatives improved the abnormal expression of mitogen-activated protein kinases activation-dependent inflammation- and apoptosis-related protein and caused less renal damage. These results provide important evidence that <TEX>$ N$</TEX>-(<TEX>$ p$</TEX>-coumaroyl) serotonin and <TEX>$ N$</TEX>-feruloylserotonin exert a pleiotropic effect on several parameters related to oxidative stress, inflammation and apoptosis. The derivatives also have a renoprotective effect in cisplatin-treated mice; however, this effect is higher with <TEX>$ N$</TEX>-(<TEX>$ p$</TEX>-coumaroyl) serotonin.</P>
Park, Chan Hum,Lee, Ah Young,Kim, Ji Hyun,Seong, Su Hui,Jang, Gwi Yeong,Cho, Eun Ju,Choi, Jae Sue,Kwon, Jungkee,Kim, Young Ock,Lee, Sang Won AMERICAN JOURNAL OF CHINESE MEDICINE INC 2018 The American journal of Chinese medicine Vol.46 No.1
<P>Cisplatin, a platinum chelate with potent antitumor activity against cancers of the testis, ovary, urinary bladder, prostate, and head and neck, has adverse effects on the kidney, bone marrow, and digestive organs, and its use is particularly limited by nephropathy as a side effect. In the present study, safflower seed extract was administered to a mouse model of cisplatin-induced acute renal failure to investigate its activity. Cisplatin (20 mg/kg body weight) was administered by intraperitoneal injection to mice that had received oral safflower seed extract (100 or 200 mg/kg body weight per day) for the preceding 2 days. Three days after the cisplatin injection, serum and renal biochemical factors; oxidative stress, inflammation, and apoptosis-related protein expression; and histological findings were evaluated. Cisplatin-treated control mice showed body-weight, food intake and water intake loss, and increased kidney weight, whereas the administration of safflower seed extract attenuated these effects (p < 0: 05, p < 0: 01). Moreover, safflower seed extract significantly decreased the renal functional parameters urea nitrogen and creatinine in the serum (p < 0: 05 and p < 0: 01, respectively). Safflower seed extract also significantly reduced the enhanced levels of reactive oxygen species in the kidney observed following cisplatin treatment, with significance. The expression of proteins related to the anti-oxidant defense system in the kidney was down-regulated following cisplatin treatment, but safflower seed extract significantly up-regulated the expression of the anti-oxidant enzyme catalase. Furthermore, safflower seed extract reduced the overexpression of phosphor (p)-p38, nuclear factor-kappa B p65, cyclooxygenase-2, inducible nitric oxide synthase, ATR, p-p53, Bax, and caspase 3 proteins, and mice treated with safflower seed extract exhibited less renal histological damage. These results provide important evidence that safflower seed extract exerts a pleiotropic effect on several oxidative stress-and apoptosis-related parameters and has a renoprotective effect in cisplatin-treated mice.</P>
고추(Capsicum annuum) callis와 검은 무늬병 유발균의 elicitor를 이용한 항균물질 생산
박지은,구부연,박재영,권혜인,문슬아,조은별,이인순,박흠대 대구대학교 산업기술연구소 2014 産業技術硏究 Vol.25 No.1
We described the effects of antimicrobial activity on a produced material by the co-culture of elicitor inducing black rot's disease and callus of Capsicum annuum that callus was induced in MS medium containing IAA 0.5 mg/ml and kinetin 2.0 mg/ml. the bacterial elicitor used 0.5% Yeast extract and the fungal elicitor made by Alternaria alternata KACC 40019 with PDB medium. In order to produce antimicrobial agent protective balck rot's disease, we co-cultured the fungal elicitor or bacterial elicitor with the red pepper callus tissue for 7days repectively. The result, an antifungal agent was produced extracellular materials into medium during co-culture red pepper callus with the fungal elicitor. The antifungal activity of the extracellular material was showed 23% inhibition rate on Alternaria alternata KACC 40019 on the other hand the intracellular material was showed 2% inhibition rate. A chitinase activity of extracellular material was also showed higher value than a chitinase of the intracellular material. The extracellular material produced by elicitor was had more 15% of andtibacterial activity than the intracellular material. As a result, a biotic stress as a fungal elicitor and a bacterial elicitor brings a defence system in the red pepper callus and induce to synthesis in extracellular material an antimicrobial agent as a chitinase and phytoalexin.