비만환자의 전기지방분해침 시술 후 허리둘레 감소에 대한 임상적 고찰

김정환 ( Jeong Hwan Kim ),고연석 ( Youn Seok Ko ),이정한 ( Jeong Han Lee ),원재균 ( Jea Kyun Won ),신병철 ( Byung Cheul Shin ),권영달 ( Young Dal Kwon ),송용선 ( Yung Sun Song ) 한방재활의학과학회 2005 한방재활의학과학회지 Vol.15 No.3

Objectives : To see if there were any differences in waist circumference reduction when certain variable such as age, sex, BFR(BFR; Body Fat Rate), PIBW(PIBW; Percent Ideal Body Weight), WHR(WHR; Waist Hip Ratio) and BMI(BMI; Body Mass Index) were given. Methods : Among outpatients who admitted to department of Oriental Rehabilitation Medicine, Jeon-Ju Oriental Medicine Hospital, Won-kwang University from August 2003 to september 2004, 89 obese patients were chosen and electroacupunture was practiced to these groups in order to treat abdominal obesity and waist circumference reduction. Results : There were no significant correlation between sex, age and waist circumference reduction. Compared to groups who had shown lower BMI, higher BMI groups have shown greater change in waist circumference reduction. As BFR increase waist circumference reduction tended to increase as well. Conclusions : From the above results, higher BMI groups had shown greater change in waist circumference reduction compared to lower BMI groups.

물류산업의 국민경제적 파급효과 분석

정동원 ( Dong Won Jeong ),한종호 ( Jong Ho Han ) 한국물류학회 2012 물류학회지 Vol.22 No.2

물류산업은 경제 발전에 중요한 역할을 담당하며, 산업경쟁력과 국가경쟁력을 결정하는 중요한 요소로 작용하고 있다. 본 논문에서는 산업연관분석을 이용하여 물류산업의 국민경제적 파급효과를 분석하고자 한다. 먼저 수요유도형 모형을 이용하여 물류산업의 타 산업 생산유발효과, 부가가치 유발효과, 취업유발효과를 살펴본다. 다음으로 상대적으로 복잡성 때문에 잘 사용되지 않았던 공급유도형 모형 및 레온티에프 가격모형을 적용하여 물류산업의 공급지장효과 및 물가파급 효과를 살펴본다. 이러한 분석은 모두 물류산업을 내생부문이 아닌 외생부문으로 다룸으로써 물류산업을 중심으로 이루어지게 된다. 주요 분석결과를 요약하면 다음과 같다. 물류산업의 1원 생산은 타 산업의 생산을 0.5104원만큼 유발하며, 타산업의 부가가가치를 0.1722원만큼 유발한다. 또한 물류산업의 10억원 생산은 타산업에서 2.2554명의 취업을 유발한다. 한편 물류산업에서 1원의 공급이 이루어지지 못할 때, 타 산업에서는 0.9387원의 생산차질이 발생하여 공급지장효과가 제법 큰 편이다. 마지막으로 물류산업의 가격이 10& 상승했을 때, 국민경제 전체적으로 미치는 물가파급효과는 0.0276%로 분석되었다. The logistics industry in Korea plays a major role in the national economy development and to make decision nation and industrial competitiveness, This study attempts to examine the economic impacts of the logistics industry using an inter-industry analysis, Specially, the study investigates production-inducting effect, value added inducing effect, and employment-inducing effect of the logistics industry based on demand-driven model. Moreover, the study deals with supply shortage effect and sectoral price effect by using supply-driven model and leontief price model, respectively, which have been rarely used because of their complications involved in computaiton. These analyses pay particular and close attention to the distribution industry by taking it as exogenous rather than endogenous. Some interesting findings emerge from the study. First, the production of 1.0 won in the logistics industry induces the production of 0.5104 won and the value-added of 0.1722 won in other industries. Second, the production of 1.0 billion won in the logistics industry causes the employment of 2.554 persons in other industries. Third, the supply shortage of 1.0 won in the logistics industry disables other industries to produce 0.9387 won. Finally, an increase of 10% in price level of the logistics industry raises the overall price level by 0.0276%.

Hypoallergenic and Physicochemical Properties of the A2 β-Casein Fraction of Goat Milk

Tae-Hwan Jung,Hyo-Jeong Hwang,Sung-Seob Yun,Won-Jae Lee,Jin-Wook Kim,Ji-Yun Ahn,Woo-Min Jeon,Kyoung-Sik Han2.6* 한국축산식품학회 2017 한국축산식품학회지 Vol.37 No.6

Goat milk has a protein composition similar to that of breast milk and contains abundant nutrients, but its use in functional foods is rather limited in comparison to milk from other sources. The aim of this study was to prepare a goat A2 β-casein fraction with improved digestibility and hypoallergenic properties. We investigated the optimal conditions for the separation of A2 β-casein fraction from goat milk by pH adjustment to pH 4.4 and treating the casein suspension with calcium chloride (0.05 M for 1 h at 25°C). Selective reduction of β- lactoglobulin and αs-casein was confirmed using sodium dodecyl sulphate-polyacrylamide gel electrophoresis and reverse-phase high-performance liquid chromatography. The hypoallergenic property of A2 β-casein fraction was examined by measuring the release of histamine and tumor necrosis factor alpha from HMC-1 human mast cells exposed to different proteins, including A2 β-casein fraction. There was no significant difference in levels of both indicators between A2 β-casein treatment and the control (no protein treatment). The A2 β-casein fraction is abundant in essential amino acids, especially, branched-chain amino acids (leucine, valine, and isoleucine). The physicochemical properties of A2 β-casein fraction, including protein solubility and viscosity, are similar to those of bovine whole casein which is widely used as a protein source in various foods. Therefore, the goat A2 β-casein fraction may be useful as a food material with good digestibility and hypoallergenic properties for infants, the elderly, and people with metabolic disorders.

A comparison study on high-temperature water–gas shift reaction over Fe/Al/Cu and Fe/Al/Ni catalysts using simulated waste-derived synthesis gas

Jeong, Dae-Woon,Jang, Won-Jun,Shim, Jae-Oh,Han, Won-Bi,Jeon, Kyung-Won,Seo, Yong-Chil,Roh, Hyun-Seog,Gu, Jae Hoi,Lim, Yong Taek Springer-Verlag 2014 JOURNAL OF MATERIAL CYCLES AND WASTE MANAGEMENT Vol.16 No.4

Shape-Dependent Charge Transfers in Crystalline ZnO Photocatalysts: Rods versus Plates

Jeong, Hye Won,Choi, Seung-Yo,Hong, Seong Hui,Lim, Sang Kyoo,Han, Dong Suk,Abdel-Wahab, Ahmed,Park, Hyunwoong American Chemical Society 2014 The Journal of Physical Chemistry Part C Vol.118 No.37

<P>ZnO particles with rod and plate configurations were synthesized using a solvothermal method using zinc acetate and zinc chloride, respectively. The surface of the as-synthesized ZnO rods and plates were characterized using various analysis tools (XRD, XPS, photoluminescence, FE-SEM, HR-TEM, BET, and UV–vis) and their photocatalytic activities were examined for six different redox reactions. The surface areas and bandgaps of the two ZnO samples were nearly identical; however, XPS and photoluminescence (PL) studies showed that the rods and the plates have relatively pronounced oxygen vacancy and oxygen interstitial contributions, respectively. ZnO rods were found to be active for the decomposition of methylene blue and phenol, the production of OH radicals, and the generation of photocurrents, all of which are associated with single-electron transfer reactions. On the other hand, ZnO plates were more effective for the production of molecular hydrogen and hydrogen peroxide, both of which are initiated by two-electron transfer reactions. These single versus multiple charge transfers are discussed with regard to the roles of oxygen vacancies and oxygen interstitials, which are located near the conduction and the valence bands, respectively.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/jpccck/2014/jpccck.2014.118.issue-37/jp506032f/production/images/medium/jp-2014-06032f_0009.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/jp506032f'>ACS Electronic Supporting Info</A></P>

The Importance of Multidisciplinary Management during Prenatal Care for Cleft Lip and Palate

Han, Hyun Ho,Choi, Eun Jeong,Kim, Ji Min,Shin, Jong Chul,Rhie, Jong Won Korean Society of Plastic and Reconstructive Surge 2016 Archives of Plastic Surgery Vol.43 No.2

Background The prenatal ultrasound detection of cleft lip with or without cleft palate (CL/P) and its continuous management in the prenatal, perinatal, and postnatal periods using a multidisciplinary team approach can be beneficial for parents and their infants. In this report, we share our experiences with the prenatal detection of CL/P and the multidisciplinary management of this malformation in our institution's Congenital Disease Center. Methods The multidisciplinary team of the Congenital Disease Center for mothers of children with CL/P is composed of obstetricians, plastic and reconstructive surgeons, pediatricians, and psychiatrists. A total of 11 fetuses were diagnosed with CL/P from March 2009 to December 2013, and their mothers were referred to the Congenital Disease Center of our hospital. When CL/P is suspected in the prenatal ultrasound screening examination, the pregnant woman is referred to our center for further evaluation. Results The abortion rate was 28% (3/11). The concordance rate of the sonographic and final diagnoses was 100%. Ten women (91%) reported that they were satisfied with the multidisciplinary management in our center. Conclusions Although a child with a birth defect is unlikely to be received well, the women whose fetuses were diagnosed with CL/P on prenatal ultrasound screening and who underwent multidisciplinary team management were more likely to decide to continue their pregnancy.

The efficacy of tenofovir-based therapy in patients showing suboptimal response to entecavir-adefovir combination therapy

( Jeong Han Kim ),( Sung Hyun Ahn ),( Soon Young Ko ),( Won Hyeok Choe ),( Kyun Hwan Kim ),( So Young Kwon ) 대한간학회 2016 Clinical and Molecular Hepatology(대한간학회지) Vol.22 No.2

Background/Aims: Before tenofovir (TDF) become available in South Korea, combination therapy with entecavir (ETV) and adefovir (ADV) was the most potent regimen for chronic hepatitis B (CHB) patients who fail to respond to rescue therapy for drug resistance. We analyzed the efficacy of ETV-ADV combination therapy and investigated the clinical and clonal results of TDF-based rescue therapy in CHB patients refractory to this combination. Methods: We retrospectively reviewed the medical records of CHB patients treated for up to 3 years with ETV-ADV combination therapy as a rescue therapy for drug resistance. In cases refractory to this combination, clinical and clonal analyses were performed for TDF-based rescue therapy. Results: The analysis was performed on 48 patients. Twelve patients achieved a virological response (VR) within 3 years. A VR was subsequently achieved in nine of the ten patients without a VR who switched to TDF monotherapy. A VR was also achieved in six of the seven patients who switched to lamivudine-TDF combination therapy, and in two of the two patients who switched to ETV-TDF combination therapy. In an in vitro susceptibility test, viral replication was detected with TDF monotherapy but not with ETV-TDF combination therapy. Conclusions: The efficacy of ETV-ADV combination therapy was insufficient in CHB patients who were refractory to rescue therapy. A more potent regimen such as ETV-TDF combination therapy may be considered in such refractory cases. (Clin Mol Hepatol 2016;22:241-249)

S-9 Long-term efficacy of tenofovir for nucleos(t)ide-naive patients with chronic hepatitis B

( Han Mu Lee ),( Joong Gi Bae ),( Hyun Seong Lee ),( Young Min Shin ),( Kyung Hye Park ),( Byung Uk Lee ),( Jae Ho Park ),( Byung Gyu Kim ),( Seok Won Jung ),( In Du Jeong ),( Sung-jo Bang ),( Jung Wo 대한내과학회 2016 대한내과학회 추계학술대회 Vol.2016 No.1

Backgrounds:?Tenofovir (TDF) is nucleoside analogue with high potency for profound and durable viral suppression and genetic barriers against resistance; TDF is recommended for the first-line treatment of chronic hepatitis B (CHB) in current guidelines, but data in Korean patients from community studies are lacking. The aim of this study was to evaluate the efficacy of TDF, and to determine patient-dependent or laboratory variables that predict virological response. Methods:?We retrospectively investigated the efficacy of TDF treatment for more than 6 months in 456 nucleos(t)ide-naive CHB patients. The primary endpoint was a virological response (VR), defined as an HBV DNA level of <12 IU/mL. Secondary endpoints were rates of ALT normalization (ALT <upper limit of normal), HBeAg seroconversion, partial virologic response (PVR), virologic breakthrough (VBT), and safety.?Results:?The median duration of TDF therapy was 22.0 (range, 6-40) months. Two hundreds sixty-five (58.1%) patients were HBeAg positive. The mean pre-treatment HBV DNA level was 6.34±1.41 log10 IU/mL. Among the 380 patients with elevated ALT levels at baseline, 343 patients (90.3%) had ALT normalization. VR was achieved in 379 patients (83.1%) during treatment. The cumulative rates of VR at 6, 12, 24 and 36 months were 53.4%, 73.2%, 90.6%, and 95.5%, respectively. PVR was evident in 208 (45.6%) patients. VBT was observed in 25 patients (5.5%). Multivariate logistic regression analysis using selected baseline factors identified absolute HBV-DNA levels at baseline (p<0.001; OR, 0.512; 95% CI, 0.397-0.661) and HBeAg positivity (p<0.001; OR, 0.781; 95% CI, 0.717-0.852) as factors showing significant association with VR. Among 265 HBeAg-positive patients, 43 (9.4%) achieved HBeAg seroconversion. Most adverse events were mild in severity.?Conclusions:?TDF is effective and well tolerated in Korean CHB patients in real life practice, consistent with larger registration trials. The lower HBV DNA levels at baseline and HBeAg-negative CHB patients were significantly associated with VR.

Therapeutic mechanisms and beneficial effects of non-antidiabetic drugs in chronic liver diseases

Han Ah Lee,Young Chang,Pil Soo Sung,Eileen L. Yoon,Hye Won Lee,Jeong-Ju Yoo,Young-Sun Lee,Jihyun An,Do Seon Song,Young Youn Cho,Seung Up Kim,Yoon Jun Kim 대한간학회 2022 Clinical and Molecular Hepatology(대한간학회지) Vol.28 No.3

The global burden of chronic liver disease (CLD) is substantial. Due to the limited indication of and accessibility to antiviral therapy in viral hepatitis and lack of effective pharmacological treatment in nonalcoholic fatty liver disease, the beneficial effects of antidiabetics and non–antidiabetics in clinical practice have been continuously investigated in patients with CLD. In this narrative review, we focused on non-antidiabetic drugs, including ursodeoxycholic acid, silymarin, dimethyl- 4,4’-dimethoxy-5,6,5’,6’-dimethylenedixoybiphenyl-2,2’-dicarboxylate, L-ornithine L-aspartate, branched chain amino acids, statin, probiotics, vitamin E, and aspirin, and summarized their beneficial effects in CLD. Based on the antioxidant, anti-inflammatory properties, and regulatory functions in glucose or lipid metabolism, several non–antidiabetic drugs have shown beneficial effects in improving liver histology, aminotransferase level, and metabolic parameters and reducing risks of hepatocellular carcinoma and mortality, without significant safety concerns, in patients with CLD. Although the effect as the centerpiece management in patients with CLD is not robust, the use of these non-antidiabetic drugs might be potentially beneficial as an adjuvant or combined treatment strategy.

Distribution and Identification of Spore-Forming Bacillus Species in Raw Milk

Won Seo Park,Jayeon Yoo,Subin Jo,Jae-Young Hwang,Gi Sung Han,Seok-Geun Jeong,Jun Sang Ham 한국식품영양과학회 2016 한국식품영양과학회 학술대회발표집 Vol.2016 No.10