제조업 생산직에 종사하는 장애근로자의 노동생산성 연구

나운환,류정진 한국장애인재활협회 2002 재활복지 Vol.6 No.2

본 연구는 일반 노동시장에 고용되어 있는 장애인 근로자의 물적 노동생산성을 비장애근로자와 비교하여 장애유형과 정도에 따라 어떤 차이가 있는지 측정해 봄으로써 장애가 생산성을 저하시킨다는 우리 사회의 지배적인 생각을 실증적으로 검증해 보고, 장애인 고용활성화를 위하여 점차 확대되어가고 있는 사업주 지원제도 중 생산성 손실 보전 차원에서 지급되는 고용장려금의 합리적인 기준마련을 위한 기초자료를 제공하고자 하는 것이다. 본 연구에서 나타난 결과는 장애유형별, 장애정도별 생산성은 차이가 없는 것으로 나타나 현행 장애인고용장려금 지급기준의 개선이 필요한 것으로 나타났으며 중증 및 여성장애인의 고용확대라는 실질적인 효과를 달성하고 기금의 효율적인 사용을 위하여 우선 청각장애인 및 지체장애인 일부를 중증에서 제외하는 것을 고려하고 사업주의 실제 손실비용을 업종별로 조사할 필요가 있는 것으로 분석되었다. 또한, 실제 뇌병변장애 등 고용에 제약이 큰 장애인에 대한서비스 개발이 필요하며 제한된 기금을 이들 대상집단에 우선적으로 투입하고 재활방향도 사회적 장애관을 기본 철학으로 바꾸어야 한다. 즉, 장애인의 능력개발서비스 중심에서 사회적 환경개선서비스 중심으로 방향을 바꾸어야 하며 학력이나 경력, 기능 등 개인의 인적자본 개발도 물론 소홀히 할 수 없으나 사회적 제약을 해소해 주는 제도와 정책개발이 더 우선되어야 하며 이를 통하여 장애인고용확대 및 직업생활유지에 실질적인 효과를 거들 수 있을 것이다. The people with disability in Korea is the weakest labor class in the labor market. For there is a distinction of the people with disability in the labor market. nevertheless the problem of the fall in the productivity of the people with disability can not be ignored. Therefore we should prove the truth of the difference of the productivity between the people with disability and the people without disability, and set a prejudice against the people with disability with the proof. Also a bounty for employment of the people with disability which is one of the support systems for the employment promotion for the people with disability is provided against the monetary lobs of the employee, nevertheless the fund for the employment promotion for the people with disability has been wasted because there is no reasonable standard of the compensation for the monetary lobs of the employee. The purpose of this study is to prove the difference of the productivity caused by the degree of the disability and the sex and to suggest the better direction of a bounty for employment promotion for the people with disability. The compared productivity between the factory laborers without disability and the ones with disability who get the job with help of Korea Employment Promotion Agency for the Disabled(KEPAD) and works at the manufacturing industry in Chung-Buk Province has been looked in this study which carried out in April(2002). With the consequence of this study, first, because the sample which consist of the laborers with disability are not paid up to their level of education and carrier, the result shows that when placing jobs it may require more specialized intervention, secondly, since there were no significant differences between the types and the degree of disability, it shows that the current standards of disability need to be re-adjusted, finally. considering the average the productivity of the laborer without disability to be 1, the average the productivity of the laborer with disability is 0.943 so the standard of the payment of the current bounty for employment for the disabled needs to be revised. However the sample size is too small to generalize the consequence of this study.

중등교육이후의 장애인 고용촉진정책과 과제

나운환,유정진 한국특수교육문제연구소 2003 특수교육저널 : 이론과 실천 Vol.4 No.4

1981년의 세계장애인의 해와 1988년 장애인올림픽은 한국에 있어 장애인의 중등교육 이후 서비스인 고용촉진정책을 개선하는데 중요한 계기가 되었다. 즉, 1981년 세계장애인의 해는 장애인의 지역사회의 완전참여와 평등을 실현하기 위한 정책형성을 시작하게 하였으며, 이후 세계장애인의 행동계획, 아시아․태평양장애인10년, 장애인의 기회균등을 위한 표준규칙의 선포 등은 한국정부의 장애정책의 기본지침을 제공하는 역할을 하였다. 한국은 이런 국제적 영향으로 짧은 기간동안에 많은 장애인을 위한 제도와 법적체계를 확립하였으며 중등교육 이후 서비스인 고용촉진정책도 상당한 성장을 이룬 것은 사실이다. 그러나 많은 연구결과물들은 고용촉진정책의 효과성이나 기대에 있어서는 많은 문제가 있음을 지적하였으며 본 연구는 그동안의 정책과 제도, 연구물들을 통해 장애인고용촉진정책의 문제와 개선방안을 제시하고자 하였고 연구의 결과를 요약하면, 첫째, 그동안의 고용촉진정책은 지나치게 경증장애인을 위한 경쟁고용에 한정되었음으로 중증장애인에 대한 고용촉진정책의 개발이 필요하며, 둘째, 중증장애인의 고용률이 늘어나지 않은 이유는 할당고용제도의 한계와 적용대상사업체의 300인이상 제한으로 지적되며, 이것을 해결하기 위해서는 장애차별법의 제정이 불가피하며, 셋째, 지금까지의 고용촉진정책은 중증장애인의 고용을 지나치게 비용/편익문제로 해결 하려고 한 결과이므로 중증학교 이후 서비스에 있어 기회균등, 평등의 개념을 적극 도입할 필요가 있으며, 넷쩨, 경쟁고용, 일반고용, 지원고용 등 다양한 중증장애인을 위한 고용시스템을 국가정책으로 도입할 필요가 있으며, 마지막으로 장애인의 고용촉진정책을 보다 효과적으로 해결하기 위한 상시적인 연구, 개발을 위한 시스템이 필요하다는 것이다. Thus, this study aimed at investigating the actual condition of job promotion policies for people with disabilities. The methods of study analysis from public data to multiple literature and applications of formal job promotion policies model. Taking into consideration all analysis, Korea's job promotion policies for people with disabilities did not improve. In this regard, the following should be implemented to improve employment policies: First, competitive employment should focus on the industrial manpower supply of both significant disabled and mildly disabled person. Also, establish a basic infrastructure for successful creation of jobs for persons with significant disabilities. Second, the employment quotas for disabled persons now applied to businesses employing 300 or more workers should be extended to cover small and medium-sized businesses so that they will have incentives to employ disabled persons. Eventually, enacting a Disability Discrimination Act would decrease the employment discrimination of individuals with disabilities. Third, employment for persons with significant disabilities who face great difficulty in finding competitive workshould be supported and developed as a means of living so that economic output and human values are given equal importance. Fourth, both competitive and sheltered employment as well as supported employment for the disabled should be covered as the policy of the government. The policy should serve the purposes of increasing industrial productivity and inclusion, and to improve the employment situation. Fifth, study, development and introduction of new and diverse job promotion policy schemes for the disabled also should be aggressively explored in the future.

혈당측정기 GlucoDr™ System의 평가

박철영,류미숙,우정택,김성운,김진우,김영설,안규정 대한당뇨병학회 2002 임상당뇨병 Vol.3 No.2

연구배경: 당뇨병 환자에서 엄격한 혈당조절은 환자의 예후와 밀접한 관련이 있다. 혈당조절을 철저히 하기 위해서는 자가 혈당 측정기의 사용이 필수적이라 할 수 있다. 또한 저혈당이 빈번하게 발생하거나, 위험요소가 있는 환자들에게도 유용하게 사용될 수 있다. 이에 저자들은 전기화학감지법의 원리를 이용하여 국내에서 처음 생산된 자가혈당측정기인 GlucoDr™ blood Glucose Testing System(ALL Medicus, Co, Korea)를 현재 국내에서 시판되고 있는 다른 제품과 비교, 평가하여 임상적 유용성을 살펴보고자 하였다 방법: 혈당측정기준장비는 YSI 2300 STAT Plus(YSI Incorporated, USA)를 사용하였으며 GlucoDr™외에 Glucocard(KDK, Japan), Precision QID(Abbott Laboratories, Co, USA), Glucotrend(Roche, USA), Surestep(Lifescan, USA)의 다른 혈당측정기를 같이 평가하였다. 정밀도, 직선성, 비교방법과의 상관관계 평가, 검체량에 따른 영향, 헤마토크리트에 따른 영향, 검사자에 따른 영향, 항응고제에 따른 영향들을 평가하였다. 결과: 본 연구에서의 주된 평가대상인 GlucoDr™의 평가결과, 정밀도를 나타내는 검사 내, 검사 간 변이계수는 8%이내였으며, 45~500mg/dL 범위에서 R²=0.9906, 0.9984 정도의 직선성을 나타내었다. 본 연구에 있어 비교방법으로 이용한 YSI 2300 STAT Plus와의 상관관계 및 정확도는 y = 1.0058x + 0.453, R = 0.9853인 것으로 나타났다. 검체량이나 검사자 및 항응고제에 따른 측정값에는 유의할만한 차이가 없는 것으로 나타났으나, 헤마토크리트가 증가 또는 감소함에 따라 최소 10%에서 최대 26% 가량의 영향을 받는 것으로 관찰되었다. 결론: GlucoDrTM는 국내 사용되는 다른 혈당측정기와 비교하여 유용할 것으로 생각된다. Background: Self-monitoing blood glucose devices are sidely used in monitoring and point-of-care testing for the management of diabetic patients. We performed the present study to evaluate the performance of the GlucoDr™ blood glucose testing system using an electrochemical technique. Method: The GlucoDr™ was evaluated for linearity, precision, comparison of method, the effect of sample volume, hematocrit concentration, reapplication, operator and application methods. Results: The GlucoDr™ showed good linearity for glucose concentrations ranging from 52mg/dl to 475mg/dl(r²=0.971). The single day, and day-to-day, CV were within 8%. Excellent correlation was found between the GlucoDr™ and YSI 2300 STAT Plus(y=1.0058x + 0.453, r²=0.9710). The sample volume, reapplication, operator and application method produced no significant effect on the test result. An overestimation in the glucose values was found with low hematocrit concentrations. There was no significant effect by the anticoagulants, with the exception of citrate. Conclusion: The GlucoDr™ showed good linearity, precision and correlation with the reference method and provided rapid and reliable result for blood glucose levels. Therefore, the GlucoDr™ seems appropriate for clinical use in the management of diabetic patients.

유육종증 1례

전수영,정운태,황성보,류종철,최수전,고일향 인제대학교 1993 仁濟醫學 Vol.14 No.4

저자들은 폐결핵 추정하에 치료를 받았던 Sarcoidosis 환자 1례를 경험했기에 문헌적 고찰과 함께 보고하는 바이다. Sarcoidosis is a granulomatous disease of unknown etiology In which pulmonary manifestations typically predominate with protean extrapulmonary and systemic manifestations. In sarcoidosis, pulmonary symptoms include dyspnea on exertion, non-productive cough and wheezing. Typical radiologic finding is a diffuse infiltration with or without bilateral symmetric hilar lymphadenopathy. Sarcoidosis should be differentiated with pulmonary tuberculosis because of its clincal and radiological slmilarity in Korea, an endemic area of pulmonary tuberculosis. We report a case of sarcoidosis patient whose symptoms were not improved by treatment with anti-tuberculous medication, but by steroid therapy following the diagnosis of sarcoidosis made by biopsy.

뇌혈관질환을 동반한 당뇨병 환자에서 지속적 혈당측정의 유용성 평가

정성훈,강인구,박철영,류미숙,우정택,김성운,김진우,김영설 대한당뇨병학회 2002 임상당뇨병 Vol.3 No.2

연구배경: 뇌혈관질환을 동반한 고령의 당뇨병환자는 이들의 신경학적 결손으로 경고 증상없이 심한 저혈당에 노출될 가능성이 크다. 실제로 하루 4번 정도의 자가 혈당 측정으로는 이를 감지하기 어려울 뿐 아니라 검사에 따른 고통으로 적극적인 혈당 조절에 제한이 따르게 된다. 이에 저자들은 Mini Med사의 지속적 혈당측정기(CGMS, continuous glucose monitoring system)를 이용하여 뇌혈관질환을 동반한 당뇨병 환자에서 24시간 혈당의 변동양상을 알아보고 각기 다른 인슐린 치료방침에 따른 혈당조절의 효율성을 비교하고자 하였다. 방법: 2001년 1월부터 6월까지 경희대학교 부속병원에 입원해 있는 10명의 뇌혈관질환을 동반한 제 2형 당뇨병환자를 대상으로 하였다. 이 들은 모두 튜브식이를 받고 있엇고 최소 1개월 이상 인슐린 치료를 시행 받았다. 지속적 혈당측정기를 착용하고 3일간의 연속적인 혈당을 측정하였고, 치료 첫 날은 NPH, 둘째 날은 속효성 인슐린과 NPH, 마지막 날은 혼합형 인슐린제제로 치료하여 그 효과를 비교하였다. 이들 각기 다른 인슐린 제재의 하루 총량에 차이는 없었다. 혈당치가 3.3mmol/L 미만이거나 7.8mmol/L를 초과하는 경우 그 차이값의 총합을 시간으로 나누어 이 값(△Glu)이 적을수록 치료효과가 우수한 것으로 판정하였다. 또한 당 수치가 3.3mmol/L 미만인 경우를 저혈당 event, 16.7mmol/L 초과한 경우를 고혈당 event로 임의로 정의하였고, 이를 통해 지속적 혈당측정의 유용성을 간접적으로 평가하고자 하였다. 결과: 평균 △Glu값은 첫째 날이 0.93 ± 0.43mmol/Lㆍmin?¹, 둘째날이 0.71 ± 0.29mmol/Lㆍmin?¹ 마지막 날이 0.58 ± 0.29mmol/Lㆍmin?¹로서 서로 다른 3가지 치료방침사이에 통계학적으로 유의한 차이는 없었다(p=0.115). 10명의 환자들 중 자가 혈당측정기로는 1명에서 저혈당 event, 2명에서 고혈당 event를 인지하였으나 지속적 혈당측정기로는 각각 9명에서 event를 확인하였다. 결론: 지속적 혈당측정기를 이용한 각각의 인슐린 치료방침에 따른 혈당조절 효율성의 차이는 없었으나, 자가혈당 측정기로는 알 수 없었던 일 중 혈당 변동사항을 정확하게 알 수 있어, 뇌혈관질환을 동반한 당뇨병 환자에서 보다 적극적인 인슐린 치료 및 관리를 할 수 있을 것으로 생각된다. Background: Diabetic stroke patients are susceptible to hypoglycemia. However, there are many limitations in detecting hypoglycemic events, even though glucoses levels are checked 3 to 4 times per day using the fingerstick method. Therefore, we investigated the glycemic excursions and pattern in diabetic stroke patients using the continuous glucose monitoring system (CGMS, MiniMed) and its clinical utility. The other objective was to compare the treatment dfficacy between insulin regimens. Methods: From jan 2001 to jun 2001, 10 adult type 2 diabetic stroke patients wore CGMS for consecutive 3 days, which continuously checked the glucose level. NPH insulin, multiple daily injection of regular insulin ± NPH and the mixed type(Novolet 30/70, Novo Nordisk) were used on the first, second and third days of the study, respectively. If the mean delta glucose(△Glu = A+B/time, A=∑(hlucose-7.8), glucose > 7.8 mmol/l, B=∑(3.3-glucose) if, glucose < 3.3 mmol/l) was calculated in order to recognize the degree of individual glycemic changes and to compare the efficacy of each treatment diverse insulin regimen. We arbitrarily defined a glucose level less than 3.3mmol/l, as a hypoglycemic event, and more than 16.7mmol/l as a hyperglycemic event. Results: Variable patterns of glycemic changes were observed among patients with the same dosage, but a different insulin regimen. The mean △Glu was 0.93±0.43 on the first day, 0.71±0.29 on the second day and 0.58±0.29 on the third. There was no significant difference in treatment efficacy between the 3 different insulin modalities(p=0.115). Of the 10 patients, a hypoglycemic event was detected in 1 with the fingerstick method, in contrast to 9 with CGMS, with hyperglycemic events being detedted in 2 and 9, respectively. Conclusion: Continuous glucose monitoring maybe useful in providing the information necessary for optimal glycemic control in the diabetic stroke patients.

Expression of pro-opiomelanocortin and agouti-related protein in the hypothalamus of caffeine-administered rats

Jeong, Joo-Yeon,Ku, Bo-Mi,Lee, Yeon-Kyung,Ryu, Jin-Hyun,Choi, Jung-Il,Kim, Joon-Soo,Cho, Yong-Woon,Roh, Gu-Seob,Kim, Hyun-Joon,Cho, Gyeong-Jae,Choi, Wan-Sung,Kang, Sang-Soo The Korean Society for Integrative Biology 2011 Animal cells and systems Vol.15 No.3

In the present study, we examined the effects of caffeine on food intake and body weight, and pro-opiomelanocortin (POMC) and agouti-related protein (AgRP) expression in the hypothalamus. Rats were administered intraperitoneally with 100 mg/kg caffeine (a high, non-toxic dose) or saline during the light phase. Intraperitoneal administration of caffeine induced a significant reduction in food intake and body weight 12 hr after treatment. In addition, POMC expression was significantly increased and AgRP expression was decreased in the arcuate nucleus (Arc) after caffeine treatment. These results demonstrate that administration of caffeine up-regulates POMC expression and down-regulates AgRP expression in the Arc, suggesting that the activation of the hypothalamic POMC neurons and inhibition of the AgRP neurons might play a role in the regulation of food intake and body weight by caffeine.

Photodynamic and photothermal tumor therapy using phase-change material nanoparticles containing chlorin e6 and nanodiamonds

Ryu, Tae-Kyung,Baek, Seung-Woon,Kang, Rae-Hyung,Jeong, Ki-Young,Jun, Dae-Ryong,Choi, Sung-Wook Elsevier 2018 Journal of controlled release Vol.270 No.-

<P><B>Abstract</B></P> <P>This paper describes the fabrication and evaluation of phase-change material (PCM) nanoparticles containing chlorin e6 (Ce6) and nanodiamonds (NDs) for photodynamic and photothermal approaches for tumor therapy, respectively. The temperature of the PCM nanoparticles containing NDs (ND/PCM, 0.5mg/mL in water) is increased to 45°C during laser exposure for 5min. The singlet oxygen generation intensity of PCM nanoparticles containing Ce6 and NDs (Ce6/ND/PCM) is gradually increased with respect to the laser exposure time. Also, the release of Ce6 from Ce6/ND/PCM can be controlled in an on-and-off manner using laser. Cell ablation tests reveal that Ce6/ND/PCM greatly ablates KB cells upon laser exposure, which is attributed to both the temperature increase in the media and singlet oxygen generation by the released Ce6. In an animal model, tumor volume is notably reduced over time after the intratumoral injection of Ce6/ND/PCM and subsequent laser exposure with a higher efficiency compared to ND/PCM. The Ce6/ND/PCM can be a promising nanomedicine for tumor therapy.</P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

악골에 발생한 악성 섬유성조직구종 2례

정종철,최홍란,오희균,박준아,류선열,이종호,김영운,정숭룡 大韓顎顔面成形再建外科學會 1995 Maxillofacial Plastic Reconstructive Surgery Vol.17 No.3

Malignant fibrous histiocytoma rarely occurs in the jaws. Although the histogenesis of this tumor remains controversal, it is best regarded as a primitive and pleomorphic nature reflected by collagen production and occasional phagocytosis. It is common for metastatic foci to appear in lung and regional lymph node. There are variable treatments such as radiotherapy, surgical excision or combination, therapy of surgical excision, chemotherapy and radiotherapy. With the review of literatures, the authors report the clinical study of two cases of malignant fibrous histiocytoma of the jaw.

Ubiquitous magneto-mechano-electric generator

Ryu, Jungho,Kang, Ju-Eun,Zhou, Yuan,Choi, Si-Young,Yoon, Woon-Ha,Park, Dong-Soo,Choi, Jong-Jin,Hahn, Byung-Dong,Ahn, Cheol-Woo,Kim, Jong-Woo,Kim, Yang-Do,Priya, Shashank,Lee, Seung Yong,Jeong, Seongsu The Royal Society of Chemistry 2015 Energy & environmental science Vol.8 No.8

<P>Stray magnetic field considered as harmful noise for the human body can be a ubiquitous energy source. We are surrounded with 50/60 Hz parasitic magnetic noise arising from power delivery infrastructure, but it cannot be readily utilized by traditional electromagnetic harvesters. Here, we introduce a novel magneto-mechano-electric (MME) generator with a colossal power density that can turn on 35 LEDs and drive a wireless sensor network under a weak magnetic field of 5–7 × 10<SUP>−4</SUP> T at a low frequency of 60 Hz. The MME generator is a cantilever structured magnetoelectric (ME) laminate composite in which the ⟨011⟩ oriented anisotropic single crystal fiber composite (SFC) is bonded to Ni plate and Nd permanent magnet proof mass. The ME laminate composite has a strong ME coupling (<I>α</I><SUB>ME</SUB>∼ 160 V cm<SUP>−1</SUP> Oe<SUP>−1</SUP>) even without magnetic bias due to the intrinsic property of Ni. The MME generator is also found to exhibit a colossal output power density of 46 mW cm<SUP>−3</SUP> Oe<SUP>−2</SUP> under a weak magnetic field of 1.6 × 10<SUP>−4</SUP> T at 60 Hz. This MME generator can be a ubiquitous power source for wireless sensor networks, low power electric devices, and wireless charging systems by harvesting tiny amounts of parasitic magnetic energy from our living environment.</P> <P>Graphic Abstract</P><P>A novel energy capturing technique for wasted parasitic magnetic noise based upon a magneto-mechano-electric (MME) generator, consisting of piezoelectric single crystal fibers and Ni metal plate in the form of cantilever structure. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c5ee00414d'> </P>

Testosterone-encapsulated Surfactant-free Nanoparicles of Poly(DL-lactide-co-glycolide): Preparation and Release Behavior

Jeong, Young-Il,Shim, Yong-Ho,Song, Ki-Chan,Park, Youeng-Guen,Ryu, Hwa-Won,Nah, Jae-Woon Korean Chemical Society 2002 Bulletin of the Korean Chemical Society Vol.23 No.11

Since surfactant or emulsifiers remained on the nanoparticle surface significantly affect the physicochemical properties, the biodegradation rate, the biodistribution, and the biocompatibility of nanoparticles, surfactant-free nanoparticles should be good candidate. surfactant-free PLGA nanoparticles were successfully prepared by both the dialysis method and the solvent diffusion method. The PLGA nanoparticles prepared using the solvent diffusion method has a smaller particle size than the dialysis method. The solvent diffusion method was better for a higher loading efficiency than the dialysis method but the nanoparticle yield was lower. Testosterone (TST) release from the PLGA nanoparticles was dependent on the particle size rather than the drug contents. Testosterone release from the PLGA nanoparticles prepared by the solvent diffusion method using acetone was faster than those prepared by the dialysis method. TST release from the PLGA nanoparticles prepared by the solvent diffusion method using acetone and the dialysis method using dimethylformamide (DMF) was completed for 4 days while the PLGA nanoparticles prepared by the dialysis method using acetone showed approximately 80% TST release after 4 days. Since the PLGA nanoparticle degradation ratio was below 20% within 5 days at all samples while TST release completed within 4 days, TST release was dependent on the diffusion mechanism rather than degradation.