인천지역 TDI 노출 작업자에서 직업성천식 유병율

김형렬,김철우,홍윤철,전형준,김치년,김현수,이지나,신주연,고동희,노재훈 大韓産業醫學會 2004 대한직업환경의학회지 Vol.16 No.2

목적 : TDI는 직업성천식을 일으키는 대표적인 물질로 알려져 있다. 과거 TDI에 노출된 작업자들의 천식 발생률을 5~6%가량 보고하였고, 국내에서도 2-20%에 이르는 유병율을 보고한바 있다. 작업환경이 많이 개선되고, 노출량이 감소된 최근에도 TDI에 의한 직업성천식에 대한 보고가 많이 이루어지고 있어, 이에 대한 적극적인 조사와 진단과정을 통해 유병율을 구하고 질병발생의 변화양상을 파악해 보고자 하였다. 방법 : 인천지역에서 특수건강진단을 수행하는 2개 기관의 TDI 노출 근로자 400여명 중, 사업장의 규모가 50인 이상이며 사업주가 연구진행을 허락한 사업장에서 근무하는 근로자 중 직접적으로 TDI에 노출되는 작업에 종사하는 근로자 170명을 연구대상으로 하였다. 이들에 대해 설문지와 산업의학의사의 면담을 통한 작업관련성 평가를 근거로 정밀대상자를 선정하고 이들에 대해 메타콜린 유발시험, TDI 유발시험 등을 수행하여 직업성천식을 확인하였다. 결과 : 설문조사 결과 11명이 직업과 관련하여 천식증상을 보이는 것으로 나타났고(6.9%), 이중 7명에서 메타콜린 유발검사 양성소견을 보였다. TDI에 의한 특이유발시험 결과 1명에서 양성반응이 나타나, 이 집단에서 TDI에 의한 직업성천식의 유병율은 0.58%였다. 결론 : 과거 국내연구에서 TDI에 의한 직업성천식의 유병율이 2~20%에 이르렀던 데 비해, 본 연구에서는 0.58%로 나타났다. 이는 국외 논문에서도 나타나는 경향으로 작업장 노출량 감소로 점차 발생률이 감소하는 양상을 보이고 있다. 그러나 이미 증상이 나타난 근로자들이 부서를 옮기거나, 직장을 그만둠으로 인해 그 유병율이 과소평가되었을 가능성도 있다고 판단된다. Objecdives: This study was carried out to estimate the prevalence of isocyanate-induced occupational asthma in toluene diisocyanate (TDI) exposed workers. Methods: We examined 170 workers who had been directly exposed to TDI through a medical questionnaire, physical examination, and pulmonary function test. Based on screening examination, workers with suspected occupational asthma were selected for further evaluation such as methacholine and TDI challenge tests. Results: Eleven (6.9%) among 170 workers complained of symptoms of occupational asthma. and 7 among these 11 symptomatic workers showed positive responses to the methacholine challenge test (4.1 %). One spray painter was confirmed as having the TDI induced occupational asthma following a positive response to TDI challenge test. Conclusions: The prevalence of TDI-induced asthma was at 0.58% was lower than that for former studies (2-20%). Improved workplace environment, lower level of TDI exposure compared to the past, and the healthy workers effect may have contributed to this low rate of asthma prevalence in workers with TDI exposure.

인삼 선발계통의 지역적응성 검정

Bong Jae Seong,Sun Ick Kim,Ka Soon Lee,Moo Geun Jee,Su Dong Kim,A Reum Kwon,Hyun Ho Kim1,Young Chang Kim 한국약용작물학회 2017 한국약용작물학술대회 발표집 Vol.2017 No.05

Background : For cultivation of varieties of ginseng, the pure line selection method, which is to select the best among those cultivated in farms for pedigree breeding, replicated yield trials and regional adaptation trials before registering as a new variety, is widely used. Although there are 25 registered varieties of ginseng in Korea, the quality of ginseng is declining together with the amount of harvest being decreased by 15 - 20% due to the heat injuries and diseases from the warming & abnormal climate. Thus, the needs for development of disaster-resistant varieties with better chances of surviving through high temperature, salts and disease are increasing. Therefore, this study is to cultivate disaster-resistant varieties among those selected for their disaster tolerance and salt tolerance through regional adaptation trials. Methods and Results : As a result of examining the growth characteristics of the selected 2 - 5 year old varieties used in the study, among the 5-year old crops, Goryeo 4 and Eumseong 5 showed superior growth in both above and below aerial parts, and among the 4-year old crops, Eumseong 11 and Cheonryang showed superior growth while the growth in the below aerial parts were satisfactory in the order of Cheonryang > Eumseong 10 > Eumseong 11 > Eumseong 9. Among the 3-year old crops, the most superior growth in both above and below aerial parts was observed in Eumseong 14 with the weight of the below aerial part, root diameter and taproot length at 13.8 g, 11.8 ㎝ and 6.2 ㎝ respectively. Among the 2-year old crops, Eumseong 10 showed the most superior growth in both above and below aerial parts. Conclusion : Based on the above results, Goryeo 4 and Eumseong 5 among the 5-year old crops, Eumseong 11 among the 4-year old crops, Eumseong 14 among the 3-year old crops and Eumseon 10 among the 2-year old crops showed the most superior growth among the selected varieties. The growth characteristics of both above and below aerial parts in each year will continuously be monitored.

푸드뱅크 기탁식품의 안전성 확보를 위한 HACCP 제도 적용

김철재,박현신,배현주,이지해,양일선,강혜승 한국식생활문화학회 2002 韓國食生活文化學會誌 Vol.17 No.3

The purpose of this study was to analyze the problems arising from the actual conditions of the Foodbank, and to implement the HACCP system as a solution in terms of increasing the safety of donated food within the Foodbank. In order to apply HACCP system, the entire Foodbank working process such as preparation, collection, transportation, division, and distribution was considered and analyzed to decide the application point for CCPs. Donated foods mainly consisted of processed foods, raw materials, lunch boxes, and cooked foods from mass catering establishments, which dominated over the others in terms of quantity. Cooked foods were divided into three groups based on menu-types and processing methods. Temperature, pH, and aw were measured on cooked foods, and Total Plate Count, Coliforms, E. coli, Salmonella spp., Staphylococcus aureus, Listeria monocytogenes, and E. coli O157:H7 were conducted in order to apply a HACCP plan. Form these experiments, temperature, pH, and aw of donated food were likely contributed to microbial growth. Donated foods before HACCP implementation showed high numbers in terms of total plate count and Coliforms, both well over the acceptable standard levels. By setting the CCPs on maintenance of donated food below 10℃ and using a 75 ℃ reheating method, microbiological hazard levels were able to be controlled and lowered. From these results, it is concluded that in order to guarantee food safety, foods donated to the Foodbank must not only maintain a reasonable level of initial microbiological growth, but also must be handled properly through time and temperature controls within the Foodbank system. Furthermore, in terms of implementing the HACCP plan within the Foodbank management structure, basic food safety and sanitation measures, such as reheating facilities and various cold chain systmes such as refrigerated vehicle for food transportation are importantly needed. The training and education of Foodbank personnel and management in areas such as awareness of hygiene and safe food handling and practice are also required and necessary.

다차원 인덱싱 방식을 이용한 이미지 내용기반 검색 기법

김지현 瑞逸大學 1999 論文集 Vol.17 No.-

이미지를 위한 내용기반 검색 기법으로 다차원 인덱싱 방식을 제안하였다. 이미지 특징 추출 방법으로는 색상, 질감, 모양등이 있는데, 이미지를 구성하고 표현하는 요소로서 단일 색상(회색 레벨 이미지)과 밝기 함수만을 가정하였다. 또한 이미지 표현을 위한 패턴 인식중 2차원 모양 매칭 기법으로서 단순한 탬플릿 매칭과 특징 공간 기법을 소개하고, 내용기반 이미지 검색시 시간과 비용을 줄이기 위한 다차원 인덱싱 검색 기법으로써 색상, 질감, 모양 등 추출된 각각의 특징을 R-tree를 사용하여 분리된 특징 벡터에 매핑함으로써 성능을 개선하였다.

전자 매뉴얼을 위한 XML 문서 저장 스키마 설계

김지현,오성균 瑞逸專門大學 2000 論文集 Vol.18 No.-

일반 매뉴얼 제작 공정을 XML 문서를 기반 한 전자 매뉴얼 시스템으로 전환하는 과정에서 매뉴얼 제작 공정에 대한 분석과 문제점을 파악한다. XML 문서 설계 시 효율적인 문서 검색이 가능하도록 DFS 방문 순서에 의한 트리 구조 표현으로 적용하여 비분할 저장방식 문서 저장 시스템 설계로 XML 문서에서 추출할 수 있는 모든 정보를 엘리먼트 테이블과 경로 테이블에 저장하고, 질의 검색 시 필요한 고비용의 조인 연산을 줄임으로서 성능을 향상시킬 수 있는 저장 데이터베이스 스키마 설계를 제시한다.

혈액형에 따른 자기이미지와 의복가치

김현아;지영은;구영아;이규혜 한양대학교 2005 韓國 生活 科學 硏究 Vol.25 No.1

This study examined empirical differences of self‐image and clothing values (hedonic/utilitarian) by consumers’ blood types. One hundred and eighty one undergraduate students with diverse majors were respondents of the empirical study. A questionnaire was developed to measure students’ self image, clothing values and demographic variables including blood types. Dimensions of self‐images for undergraduate students were classified into optimistic futuristic, self‐centeredness, social, safety/ conservative, feminine, and indifferent. For hedonic aspects of clothing values four factors were extracted: novelty/ enjoyment/ charm, fashion value orientation, clothing‐confidence, and mix and match. Utilitarian aspects of clothing values consisted of five factors: symbolic/social recognition, comfortable, economic, practical, and ease of care. ANOVA results indicated no major difference of self‐images by blood type. The only significant result was found in the safe/conservative image. People of the blood type A, B and O showed lower level of safety seeking and conservatism. However, comparatively, people of type AB blood are holding back their emotion, not expressive, watchful against other people, and pursuing safety. No major differences were found in clothing value sub dimensions in conjunction with the blood types. The research findings are suggestive of existence of insufficient evidence of self‐image and clothing values by the individual’s blood style.

림프관 확장증형 모기질종 1예

김도현,김재욱,이지범,김성진,원영호,이승철 대한피부과학회 2003 大韓皮膚科學會誌 Vol.41 No.2

Pilomatricoma is a benign adnexal tumor differentiating toward elements of the hair matrix and shaft. It typically presents as a solitary, deep, dermal nodule, but other variants, such as anetodermic form and pseudo-bullous form have rarely been reported. A 22-year-old man presented with erythematous 4×5㎝ sized bulla-like nodule of about 1 month history on the upper back. Histopathologic examination of the lesion showed a well-circumscribed dermal nodule composed of basophilic cells, shadow cells, and transitional cells. There were also marked lymphangiectatic dilatations above the tumor in the upper dermis. We diagnosed this case as a lymphangiectatic pilomatricoma with pseudo-bullous appearance. (Korean J Dermatol 2003;41(2) : 258∼260)

Propofol 정맥 주사 시 Metoclopramide의 통증 완화 효과

김수진,박은지,안승원,김웅,김미운,임현술 대한마취과학회 2002 Korean Journal of Anesthesiology Vol.43 No.5

Background: Propofol is a good induction agent. but it has a disadvantage of pain on intravenous injection. Pretreatment of metoclopramide or lidocaine have been reported to reduce pain on injection. thus, we have evaluated the quantity and quality of anagesic effect of metoclopramide and lidocaine. We observed differences in quality of pain according to venous cannula sizes and intravenous injection sites as well as nausea and vomiting in the postoperative state. Methods: Eighty patients scheduled for an elective operation by general anesthesia were chosen according to ASA (Ⅰ or Ⅱ) and divided into four groups randomly. Each group was injected through venous cannulas with normal saline (control group), metoclopramide 5 mg (group 1), netoclopramide 10 mg (group 2), or 2% lidocaine 40 mg (group 3) respectively. Then, propofol was injected of a 2 mg/kg dose with 0.5 ml/sex to all groups and we asked questions about injection pain after 10 seconds. Results: Pain relief was shown in all groups compared with the control. but metoclopramide 10 mg and lidocaine 40 mg pretreatment groups showed significant pain reief. Pain was relieved significantly when the drug was injected in the antecubital area. Postoperative nausea and vomiting were not observed. Conclusions: Metoclopramide 10 mg or lidocaine 40 mg pretreatment to induction by propofol revealed a good analgesic effect for propofol injection pain. (Korean J Anesthesiol 2002; 43: 558~565)

난소화성 덱스트린이 흰쥐의 단백질과 지방이용률에 미치는 영향

김지현,왕수경 대전대학교 기초과학연구소 1995 自然科學 Vol.6 No.-

식이 중 난소화성 덱스트린이 휜 흰 쥐의 단백질과 지방의 이용율에 미치는 영향을 조사하기 위해 Sprague-Dawely계 (평균체중 109g) 흰 쥐를 3군으로 나누어 control군으로 무섬유소군(NC), 섬유소간의 비교를 위해 5% pectin군(NP), 5% 난소화성 덱스트린군(ND)으로6주간 사육하였다. 얻어진 결과를 요약하면 다음과 같다. 실험기간중 식이 섭취량은 ND군이 다른 군보다 높은 경향을 보였으나 체중증가량과 식이효율은 ND, NP군이 NC군보다 낮았다 (p<0.05). 간, 비장, 신장의 무게는 각 군간에 유의적 차는 없었다. 그러나 부고한 지방은 NP군과 ND군이 낮은 경향을 보였다. 단백질 섭취량은 NP군이 높았고, 뇨중 단백질 배설량은 ND군이 높았으며, 변중 단백질 배설량은, NP, ND군이 NC군보다 낮게 나타나 결과적으로 단백질 흡수율, 보유율은 실험군간 유의적 차를 보이지 않았다. 변 중 지방 배설량은 NP군이 높았고 ND군도 NC군보다 높은 경향을 보였다. 지방의 흡수율은 NP군이NC군보다 유의적으로 (P<0.05) 적었고, ND군도 NC군보다 적은 경향을 보였다. 따라서 난소화성 덱스트린은 식이효율이 낮아 체중 감소 효과를 나타냈으며, 이는 단백질 이용율의 감소보다는 지방이용율의 감소의 결과로 나타난 것으로 보인다. 앞으로 당 대사와의 관계와 병행해서 연구되어야 할 것으로 사료된다. This study investigated the effect of indigestible dextrin on bioavailabilities of protein and lipid. Sprague-Dawley male rats weighing 108g were blocked into three groups; control diet (NC), control + 5% pectin (NP), control + 5% indigestible dextrin (ND). Experimental rats were fed ad libitum each of experimental diets for six weeks. The results are summarized as follows. 1) food intake was generally higher in ND group than in other groups and weight gain and food efficiency ratio were significantly lower in ND, NP groups than in NC group(p<0.05). 2) Weight of liver, kidney and spleen were lower in ND group than in other groups, epididymal fat pads was lower in ND and NP groups than in NC group. 3) Protein bioavailabilities was not significantly different in three dietary groups. 4) Fat bioavailabilities was significantly lower in NP group than in NC group(p<.05) and tended to be lower in ND group than in NC group. Accordingly, weight reduction shown in ND group seems to be resulted from the decreased fat bioavailabilities.

미혼 여성근로자의 건강행태와 자각적 건강상태와의 관련요인 분석

김현지,한성현,이태용,김정선 충남대학교 의학연구소 2003 충남의대잡지 Vol.30 No.2

This study was peroformed to identify health behaviors and health problems, and the relations between health behaviors and health problems of unmarried female workers. The Cornell Medical Index Health Questionnaire(CMI) was used to measure their health problems. Survey was conducted with 973 unmarried female workers from October 2001 to March 2002. The main reason of health problems is the stress commonly in both white color workers and blue color workers. Among white color workers, smoking and stress is significantly related with respiratory system, musculoskelectal system. Stress is significantly related with digestive system, neurological system. Drinking and stress is significantly related with fatigability(p<0.05). Among blue color workers, smoking, drinking, strees is significantly related with respiratory system. Stress, smoking, eating habit is significantly related with digestive system. Stress, smoking, eating habit, hours of sleep is significantly related with musculoskeletal system. Stress, smoking is significantly related with fatigability(p<0.05).