조선초기 문신 姜希孟의 관직생활

강제훈(Kang Jae-hoon) 한국인물사연구소 2008 한국인물사연구 Vol.9 No.-

This study aimed at looking into Kang Hui-maeing's office life for the understanding of the early Joseon society dominated by yangban(two upper classes). Through reviewing on his life we can interpret constant factors to make his way in office life in Joseon as well as variable ones. He was out of top drawer, a nephew of King Sejong's wife and got the first position in the civil service examination come up 1447, King Sejong's 29th year. He enjoyed a success career during King Sejo's ruling period(1455~1468) and reached the peak point when King Seongjong rose. He started office life in 24 years old and got a dangsanggwan position, the major third rank, 10 years later. He took office as the minister of the Ceremonies Board in 1466, King Sejo's 12th ruling year. He died at 1483 with two titles as a meritorious retainers without taking the position for state councilor. Key point of his success was to have taken good results, ranked the first class, in the successive two tests by King Sejo for inservice officers. This enabled hime to get dangsoangwan and panseo post. He was a ceremony and writing expert whom the dynasty need for establishing confucian state and keeping stable relations with Ming China. He went through almost all posts in the Ceremonies Board from jwarang(assistant section chief) to panseo (Minister). He had his son got to married to a grand daughter of Sin Sukju, first class meritorious retainer. It helped him to get the meritorious title. He participated in discussion sessions with the king Seong Jong as a Gyeongyeongwan holding additional posts and meritorious retainer. Seongjong left his first son who acceded to the throne later in Kang's care for several years and nominated him for Yijo-panseo positon, Minister of Personnel. His success story shows that in Joseon society a person could not success depending solely on one's family. For successful office life it requires to be a fine writer and to get a special status like a meritorious title.

Gilbert 증후군에서 열량 제한 시험과 Phenobarbital 자극 시험의 의의(14예)

이헌영,채경훈,정재훈,강윤세,김연수,문희석,박기오,이엄석,김선문,김석현,성재규,이병석,이강욱 충남대학교 의학연구소 2003 충남의대잡지 Vol.30 No.2

Gilbert 증후군은 인구의 7%에서까지 나타날 수 있는 매우 흔한 증후군으로서 비진행성인 양성의 만성적 경과를 치하며, 간질환의 증상과 징후가 없는 경한 비포합형 고빌리루빈혈증이 특징인 일종의 체질적인 증상으로서 혈장 빌리루빈 농도에 대한 사춘기의 영향 때문에 10대와 20대에 자주 진단이 된다. 따라서 임상적인 중요성은 미약하지만 높은 빈도가 예상되는 점에 그 중요성이 부여되어야 할 것이다. 따라서 적정한 임상적 진단법으로 기왕에 소개된 열량제한 시험과 phenobarbital 유도 시험을 시행하고 이들의 진단적 가치를 알아보기 위하여 본 연구를 시행하였다. 1990년 7월부터 1999년 4월까지 충남대학교병원에 내원하여 HBsAg, IgG anti-HBc 및 anti-HCV가 음성이고, 간 초음파 스캔에서 이상이 없으며, 혈청 AST, ALT 및 AP가 정상인 비음주자에서 경한 비포합형 고빌리루빈혈증이 있는 14예의 환자들을 대상으로 ^(99m)Tc-DISID 스캔을 시행하였으며, 기저 치 총빌리루빈 및 포합형 빌리루빈 치를 측정한 다음에 하루에 400Kcal로 48시간동안 제한한 열량 제한 시험을 시행하였고, phenobarbital을 하루 60mg씩 5일간 투여한 후에도 각각 총빌리루빈과 포합형 빌리루빈 치를 검사하여 비포합형을 구하였다. 대상 환자들은 모두 14예로서 남자가 11예(78.6%)였고 여자가 3예(21.4%)여서 3.7:1로 남자에서 많았으며, 20대가 6예(42.9%), 30대가 역시 6예(42.9%) 및 40대가 2예(14.2%)로서 2,30대가 대부분(85.8%)이었다. 열량 제한 시험 후의 총빌리루빈 치, 비포합형 및 포합형 빌리루빈 치들은 평균 각각 5.5±2.7, 4.2±2.3 및 1.3±10mg/dL 로서, 시험 전 치들인 3.0±0.8, 2.2±0.8 및 0.7±0.4mg/dL 보다 유의하게(p=0.001, p=0.001, p=0.023) 상승하였다. 포합형 빌리루빈 치도 유의하게 상승하였으나 비포합형의 상승보다는 훨씬 낮아서 주로 비포합형이 증가하였다. phenobarbital 투여 중 설사가 발생하여 중단한 1예를 제외한 13예에서 열량 제한 시험 후에 상승하였던 총, 비포합형 및 포합형 빌리루빈 치가 phenobarbital 유도 시험후에는 2.0±1.1, 1.5±0.8 및 0.5±0.4mg/dL로서 열량 제한 시험 결과보다 유의하게 낮아졌고(p=0.00, p=0.000, p=0.001), 열량 제한 시험 전의 기초치들인 3.0±0.8, 2.2±0.8 및 0.7±0.4mg.dL 보다도 더욱 낮아졌으며 유의한 차이(p=0.001, p=0.02, p=0.005)를 나타내었다. 14예에서 시행한 ^(99m)-Tc DISIDA 스캔에서 9예(64.3%)가 정상이었고, 5예(35.7%)에서는 심장 및 신장으로의 간외 섭취가 3예였고, 60분까지 소장 배출이 없는 배설 지연 예와 담낭 수축 불량 예가 각각 1예 씩 발견되었다. Phenobarbital 투여시험에서 민감도가 열량제한시험에 비해 더 높았다(92.3%와 50.0%). Gilbert 증후군에서 1일 400 Kcal로 48시간의 열량제한 시험과 1일 60mg의 phenobarbital을 5일간 투여하는 유도 시험은 편리하고 유용한 임상적인 진단법으로 이용할 수 있다고 생각된다. 그러나 열량 제한 시험에서는 증가 기준의 통일이 필요하다고 유추되며 phenobarbital 유도 시험이 민감도가 더 높은 것으로 생각된다. Gilbert's syndrome is very frequent and benign chronic process characterized by mild, intermittent, unconjugated hyperbilirubinemia without any symptom and sign of liver disease. Previously intoduced caloric restriction test and phenobarbital stimulation test as two appropriate clinical tests had been examined and their diagnostic values were reevaluated. Fourteen patients with mild, persistent, unconjugated hyperbilirubinemia were included. Subsequently caloric restriction has been applicated by 400 Kcal/day for 48 hours and phenobarbital has been prescribed by 60 mg/day for 5 days. Therafter serum levels of total and direct bilirubin were measured. Most of the patients were third and fourth decade(85.8%) and male predominant. Each basal serum levels of total, indirect and direct bilirubin were 3.0±0.8, 2.2±0.8 and 0.7±0.4 mg/dL. After caloric restriction test, each levels were increased significantly to 5.5±2.7, 4.2±2.3 and 1.3±1.0 mg/dL(p=0.001, p=0.001, p=0.023). After phenobarbital stimulation test for 13 patients had been practiced, increased levels of each bilirubin after caloric restriction test were decreased significantly to 2.0±1.0, 1.5±0.8 and 0.5±0.4 mg/dL(p=0.000, p=0.000, p=0.001) and these levels were significantly lower than basal levels(p=0.001, p=0.02, p=0.005). The sensitivities of caloric restriction test were 85.7%, 50.0%, and 71.4%, 35.7%(1.0, 1.5 mg increase of total bilirubin and 1.0, 1.5 mg/dL increase of indirect bilirubin). The sensitivities of phenobarbital stimulation test were 93.2% and 92.3% at criteria of 1.5 mg/dL increase of total bilirubin and indirect bilirubin. On the diagnosis of Gilbert syndrome, caloric restriction test and phenobarbital stimulation test are convenient and useful diagnostic tools in clinical face. And also phenobarbital stimulation test has higher sensitivity than caloric restriction test. Furthermore, standardization of bilirubin increment would be necessary in caloric restriction test.

간세포암과 감별이 어려웠던 악성중피종 치험 1예

김선문,허원석,채경훈,강윤세,정재훈,김연수,박기오,문희석,이엄석,김석현,성재규,이병석,이헌영,신경숙,조준식,송인상,강대영 충남대학교 의학연구소 2003 충남의대잡지 Vol.30 No.2

Malignant peritoneal mesothelioma is a rare neoplasm that arises from the mesothelium of a serosal cavity and is a rapidly fatal disease with a median survival of 4 to 12 months for untreated cases. Recently, we experienced a case with malignant peritoneal mesothelioma who was suspected hepatocelluar carcioma by abdominal CT scan and was confirmed by biopsy including immunohistochemical stain(calretinin) after surgery. We performed tumor excisions and wedge resection of the liver(segment Ⅷ)and inserted Tencoff catheter in abdominal cavity at 25th day of post-operation. We treated with intraperitoneal paclitaxel(25mg/m^(2)/day for 5 days) six courses monthly. She was well tolerable and is still living without any evidence of recurrence for 14th month of post-operation.

볼엔드밀을 이용한 밀링공정에서의 칩형성 예측

강재훈 한국공작기계학회 2008 한국공작기계학회 추계학술대회논문집 Vol.2008 No.-

This paper presents a simple analytic method using 2D simulation program for predications of chip formation in milling process using ball end-mill. And also, comparison of chip status obtained from experiment and simulation work is accomplished to distinguish of suitability.

환경변화에 따른 절삭유상태의 비교 연구

강재훈 한국공작기계학회 2008 한국공작기계학회 춘계학술대회논문집 Vol.2008 No.-

Coolants can be regarded as an important component of various mechanical machining operations. Coolants improve machinability, increase productivity and extend tool life by cooling and lubricating action to the cutting zone between of part and cutting tool. When performing these functions Coolants can quickly become contaminated with foreign materials causing cutting fluids to lose effectiveness and develop foul odors. For this reason, most coolants are used only for a short time then discarded and especially, coolants are typically disposed of due to bacterial growth. The anaerobic bacteria can act as a skin irritant and can produce hydrogen sulfide gas which smells like rotten eggs. Proper coolants maintenance can prevent this bacterial growth. Therefore, it is desirable for prolong the coolants life to maintain properly with the consideration like as removal of tramp oil and metal chips, control of bacterial growth, maintenance of the proper cutting oil-to-water mix and additive concentrations. In this study, various experiments included with measuring concentration and pH, viscosity, hydrogen sulfide gas using multiple sensors for condition monitoring of coolants are carried out to decide proper change point of time or maintain uniform condition as long as possible.

밀링가공에서의 온도분포와 절삭력 예측을 위한 연구

강재훈,송준엽,박종권 한국공작기계학회 2004 한국공작기계학회 춘계학술대회논문집 Vol.2004 No.-

This paper presents a simple analytic method using 2D simulation program for predications of cutting force and machining temperature in dry type milling process. And also, comparison of cutting force and machining temperature obtained from experiment and simulation work is accomplished to distinguish of suitability.

연삭 공정의 연속 진단을 위한 모니터링에 관한 연구

강재훈 한국공작기계학회 1999 한국생산제조학회지 Vol.8 No.1

Recently, manufacturing work has been transformed to small scale production form with various types to act up to user's expectation from mass production with a little items required in the past. Then FMS using NC type machinaries has been applied actively also in domestic manufacturing line to meet thus tendency, but there are many machining troubles occured during work process not be settled yet. Nowdays high efficiency has been required no less than high precision in grinding work for the improvement of productivity. In this study, to represent more advanced FMS can be adapted to thus situation In-process type monitoring method using AE and Current sensors is suggested to investigatethe machining condition in grinding process. As results from this experimental study, it is recognized well that grinding conditions and dressing point of in time can be estimated effectively using monitoring method suggested. Furthermore, surface shape of grinding wheel on voluntary point of in time can be predicated indirectly through the observation and comparison of AE signal waveform obtained as performance of continuous dressing work.

황해와 동중국해 표충수온의 계절변화

강재훈,방익찬,장경일 제주대학교 해양연구소 1999 해양자원연구소연구보고 Vol.23 No.-

In order to obtain the fundamental data on the auditory thresholds of fishes for Marine ranching, the auditory thresholds of Scorpion Fish Sebastiscus marmoratus were measured in the presence of masking noise in the spectrum level range of 75 - 83dB re 1 μPal□ with a classical cardiac conditioning technique. Critical ratios were about 27 - 35dB at 300Hz and 47 - 50dB at 500 - 800Hz including 19dB at 80Hz. The ratio increased almost linearly with increasing frequency to 500Hz. The noise spectrum level at the start of masking was about 60 - 65dB within the frequency range of 80 - 3NHz and 70 - 75dB a t 80, 500 and 800Hz. This suggests that hearing of the Scorpion Fish is masked in the natural environment with the noise spectrum level above 65dB. The sound pressure level of which the signal sound of 100 - 200Hz is recognized by Scorpion Fish under the ambient noise is above WdB and the critical ratio of them is above 30dB.

난치성 급성 혼합형 백혈병 환자에 동반된 수포성 괴저성 농피증 1예

강희정,이재련,이경희,현명수,신동훈,박진우,조희순 대한내과학회 2004 대한내과학회지 Vol.66 No.2

괴저성 농피증(pyoderma gangrenosum)은 드물게 발생하는 궤양성 피부질환으로 반수이상에서 궤양성 대장염, 류마티스성 관절염, 코론병, 만성 활동성간염 및 백혈병 같은 전신질환을 동반한다. 저자들은 난치성 급성 혼합형 백혈병에 동반한 수포성 괴저성 농피증의 드문 1 예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Pyoderma gangrenosum is a neutrophilic dermatosis that may be associated acute leukemia. We report a case of pyoderma gangrenosum associated refractory acute biphenotypic leukemia wherein the malignant cells show a phenotype specific for myelogenous and lymphocytic leukemia. Histopathologic examination revealed moderate perivascular infiltrate consisting mainly of neutrophils and lymphocytes without involvement of leukemic cells in the skin lesions. Treatment with systemic steroid was followed by a characteristically rapid healing of the skin lesions.

퍼지 동적 시스템의 카오틱 현상:"퍼지 큐빅 맵"

강훈,제갈욱 중앙대학교 생산공학연구소 1996 생산공학연구소 논문집 Vol.5 No.1

본 논문의 목적은 퍼지 동적 시스템이 기존의 비선형 시스템에서 알려진 것들과 비슷한 카오틱 다이내믹스와 카오틱 현상을 어떻게 보일 수 있는가에 대해서 다룬다. 그리고 큐빅 맵의 퍼지 카오틱 모델이 같은 바이퍼케이션 다이어그램을 갖고, 안정한 평형점, 피리어드 더블링, 카오틱 어트렉터를 갖는다는 사실을 보인다. The objective of this paper is to demonstrate how fuzzy dynamic systems can show chaotic phenomena and chaotic dynamics similar to those found in a class of nonlinear systems. We found that the fuzzy chaotic dynamic model of a cubic map results in the same bifurcation diagrams and that it shows stable equilibrium points, period-doubling, and chaotic attractors.