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( Sun-uk Bak ),( Suji Kim ),( Hae-jun Hwang ),( Jung-a Yun ),( Wan-sung Kim ),( Moo-ho Won ),( Ji-yoon Kim ),( Kwon-soo Ha ),( Young-guen Kwon ),( Young-myeong Kim ) 생화학분자생물학회(구 한국생화학분자생물학회) 2017 BMB Reports Vol.50 No.2
Heme oxygenase (HO-1) catalyzes heme to carbon monoxide (CO), biliverdin/bilirubin, and iron and is known to prevent the pathogenesis of several human diseases. We assessed the beneficial effect of heme degradation products on osteoclastogenesis induced by receptor activator of NF-κB ligand (RANKL). Treatment of RAW264.7 cells with CORM-2 (a CO donor) and bilirubin, but not with iron, decreased RANKLinduced osteoclastogenesis, with CORM-2 having a more potent anti-osteogenic effect. CORM-2 also inhibited RANKLinduced osteoclastogenesis and osteoclastic resorption activity in marrow-derived macrophages. Treatment with hemin, a HO-1 inducer, strongly inhibited RANKL-induced osteoclastogenesis in wild-type macrophages, but was ineffective in HO-1<sup>+/- </sup>cells. CORM-2 reduced RANKL-induced NFATc1 expression by inhibiting IKK-dependent NF-κB activation and reactive oxygen species production. These results suggest that CO potently inhibits RANKL-induced osteoclastogenesis by inhibiting redox-sensitive NF-κB-mediated NFATc1 expression. Our findings indicate that HO-1/CO can act as an antiresorption agent and reduce bone loss by blocking osteoclast differentiation. [BMB Reports 2017; 50(2): 103-108]
실용음악 전공 학생들의 발성치료 전후 성대 및 음성 특성 비교
황연신,심미란,김철준,최용석,김상연,최찬호,선동일,Hwang, Yeon Shin,Shim, Mi Ran,Kim, Chul Jun,Choi, Yong Suk,Kim, Sang Yeon,Choi, Chan Ho,Sun, Dong Il 대한후두음성언어의학회 2016 대한후두음성언어의학회지 Vol.27 No.2
Background and Objectives : Many students major in applied music singing have various difficulties in phonation when they sing or perform. But the studies about this cause are lack. The purpose of this study is whether singing voice therapy based on vocal music is effective or not to applied music singing students that have difficulties in phonation. Materials and Methods : Singing voice therapy program had been done to 8 students major in applied music singing during 7 weeks. We did laryngeal stroboscope, perceptual, acoustic and aerodynamic examination before and after singing voice therapy to this students. And we studied post examination results have differences or improvements compared to pre examination results. Results : Four male students don't have effective improvement after singing voice therapy but they shows slight improvement in aerodynamic examination values compared to pre examination values. Four female students shows improvement in aerodynamic examination values and pitch range increasing. Above all, one student's vocal nodules disappeared after singing voice therapy. Conclusion : Singing voice therapy based on music singing is very effective to the students major in applied music singing. Above all, their curriculum in applied music singing should include phonation training based on music singing before training perform and technic practices.
요통(腰痛) 환자에 대한 침치료(針治療)와 직접구(直接灸) 병행치료(竝行治療)에 대한 비교(比較) 연구(硏究)
위종성,원승환,황정수,선승호,안영민,손승현,박기철,박희수,We, Jong-sung,Won, Seung-hwan,Hwang, Jung-soo,Sun, Seung-ho,Ahn, Young-min,Sohn, Seung-hyun,Park, Ki-chul,Park, Hee-soo 대한침구의학회 2004 대한침구의학회지 Vol.21 No.6
Objective : The purpose of this report is to examine the effects of direct moxibustion in the Low back pain patient. Methods : Clinical studies were done 30 patients who were treated with low back pain to Dept. of Acupuncture & Moxibustion, of Oriental Medical Sang-Ji University from September 1, 2003 to August 31, 2004. We treated them by Oriental medical therapy(including direct moxibustion)for 10 days. The evaluation was performed five times(admission day, before and after each twice). Results : 1. VAS was decreased after direct moxibustion for 10 days significantly(p<0.01). 2. After direct moxibustion, S.L.R. T angle of patients were increased. ConclUsions : We brought to the conclusion that direct moxibustion has possibility to the efficient to cure the Low back pain. So we suggest the possibility to use this treatment for Low back pain.
황은범 ( Eun Bum Hwang ),남상요 ( Sang Yo Nam ),하호욱 ( Ho Uk Ha ),이창은 ( Chang Eun Lee ) 한국병원경영학회 2001 병원경영학회지 Vol.6 No.3
This study is focused that the electronic commerce(EC) on the purchasing section may improve the efficiency and transparency of the hospitals management. After reviewing the purchasing activity of hospitals, I study the introduction, expected effects, and problems of EC. So, I am going to provide basic information for activating EC. The samples are managers of 170 hospitals, which are located on Seoul. As a result of collection this survey, I analyze 79 hospitals. For data analysis, I use X^2-test and ANOVA for purchasing management and the relevance of EC according to the level of care. The results of this study are 1. the problems on the management of purchasing section are : firstly, they don't have sufficient time to study market. Secondly, it is difficult to find competitive suppliers. And, lastly, they cannot gather a lot of information about the price of products. 2. There are many answers of the needs on the introduction of B2B. However, some hospitals think they don't need it. But, the most answers are that the EC will be settled within 4 years. So, we can realize that these hospitals are getting interested on the EC. On the other hand, I find that they prefer outside EC companies for the introduction of EC. 3. On the expected effects on EC, first is the effectiveness of the market survey. The next is to collect information of adequate price of products owing to clear transaction, find easier new suppliers and gather useful data. 4. On the external problems of the introduction of EC, there is low credibility related to the security and the weakness of suppliers' information system. Especially, on the Real Transaction Price Payment system, the bigger bed size, the higher understanding on these problems. On the internal problems of the introduction of EC, first is the burden of the introduction of EC and operating cost. Especially, on the burden of the disclosure of revenue source, the smaller bed size, the higher understanding on this problem. So, this is a point which deserves my attention statistically. However, this shows relatively little understanding about incomplete the standard of product category and the weak information system of hospital. Through this study, I am going to suggest 3 points for the activation of the introduction of EC on hospitals. 1. The reform of the Real Transaction Price Payment System on medical supplies and materials for medical treatment. 2. The establishment of the standard of product category. 3. The promotion of information system based on network.
Probiotic and Anti-Inflammatory Potential of Lactic Acid Bacteria Isolated from Kimchi
Ho Jae Lee,Chang Hee Jeong,Hyelyeon Hwang,Tae Woon Kim,Sung Wook Hong 한국식품영양과학회 2021 한국식품영양과학회 학술대회발표집 Vol.2021 No.10
27 strains of lactic acid bacteria, which were isolated from various kimchi were evaluated for their probiotic potential along with anti-inflammatory activity. Seven isolates (Lb. plantarum, Lb. paracasei, Lb. fermentum) were selected and identified by 16S rRNA gene sequence analysis. Most of isolates showed a high survival rate under gastrointestinal tract conditions such as artificial gastric juice (pH 2.5) and 0.3% bile salts, and heat treatment (40, 50, and 60˚C). Antibacterial activity showed strong inhibition against food-borne pathogenic bacteria including E. coli O157:H7, Listeria monocytogenes, and Staphylococcus aureus. Moreover, they significantly decreased pro-inflammatory cytokines (IL-1β, IL-6, and TNF-α) and increased anti-inflammatory cytokines (IL-4, IL-10, IFN-γ) gene expression in LPS-stimulated Caco-2 cells. Further, functional properties of selected probiotics showed considerably higher anti-oxidation (DPPH and ABTS radical scavenging activity). Favorable probiotic properties of lactic acid bacteria from kimchi along with antioxidant and pro-inflammatory activity imply its potential for clinical or technological applications.
Hwang, Boyeon,Shin, Sang-Ho,Hwang, Soon-Hyoung,Jung, Joo-Yun,Choi, Jun-Hyuk,Ju, Byeong-Kwon,Jeong, Jun-Ho American Chemical Society 2017 ACS APPLIED MATERIALS & INTERFACES Vol.9 No.33
<P>We investigated the preparation and performance of large-area transmission-type flexible plasmonic color filters (PCFs). These large-area PCFs were fabricated based on a nanotransfer printing (nTP) process that involves nanoimprint-based planarization. This process is a simple surface treatment for easy transfer of a metal to a flexible plastic substrate and formation of patterned aluminum nanodots and nanoholes on a substrate surface with poor roughness. Rabbit-ear structures can form during the nTP process, and this phenomenon was analyzed by numerical simulation. As defects were not detected in a 10 000-round bending test, the PCFs fabricated using this nTP process have excellent mechanical properties.</P>
Migration Cost Sensitive Garbage Collection Technique for Non-Volatile Memory Systems
HWANG, Sang-Ho,CHOI, Ju Hee,KWAK, Jong Wook 'Institute of Electronics, Information and Communi 2016 IEICE transactions on information and systems Vol.99e.d No.12
<P>In this letter, we propose a garbage collection technique for non-volatile memory systems, called Migration Cost Sensitive Garbage Collection (MCS GC). Considering the migration overhead from selecting victim blocks, MCS GC increases the lifetime of memory systems and improves response time in garbage collection. Additionally, the proposed algorithm also improves the efficiency of garbage collection by separating cold data from hot data in valid pages. In the experimental evaluation, we show that MCS GC yields up to a 82% improvement in lifetime prolongation, compared with existing garbage collection, and it also reduces erase and migration operations by up to 30% and 29%, respectively.</P>
A New Rice Variety Adaptable to Direct Seeding with Lodging Tolerance, "Nonghobyeo"
Sang Jong Lim,Un Sang Yeo,No Bong Park,Byeong Geun Oh,Sae Jun Yang,Ho Yeong Kim,Heung Gu Hwang,You Cheon Song,Do Yeon Kwak,Jong Rae Kang,Woon Goo Ha,Jeom Sik Lee,Soon Chul Kim 한국육종학회 2003 한국육종학회지 Vol.35 No.1
Nonghobyeo', was derived from a mutant of Milyang 95, by pure line selection method, which was developed from the single cross between Chukei 1016 and Milyang 79, by the rice breeding team of National Yeongnam Agricultural Experiment Station (NYAES) in 19