면접조사를 통한 초등학생의 영양교육 실태 및 실천도 조사

오유진,이영미,김정현,안홍석,김정원,박혜련,서정숙,김경원,권오란,박혜경,이은주,성현이 대한지역사회영양학회 2008 대한지역사회영양학회지 Vol.13 No.4

This study investigated the experience and practice of elementary school students on nutrition education. The data were collected from 217 male and female students attending 5-6th grade elementary schools in Seoul and Kyunggi-Do from March to June 2007, interviewing face to face by a nutrition teacher and 3 interns of a nutrition teacher. The results were as follows: 86.5% of the subjects learned about ‘Table etiquette’, ‘Reasons for eating fruits and vegetables’ (78.7%), ‘Food waste and environment’ (72.3%), ‘Healthy snacks’ (55.7%), ‘Food sanitation’ (52.3%), ‘Food culture of foreign countries’ (48.1%). Nutrition education experience was significantly different by gender. A total of 43.5% boys responded that they never learned about ‘basic food preperation’ (p < 0.01). They had learned ‘Nutrients for body’ and ‘Food waste and environment’ in school, ‘Healthy weight loss’, ‘Food culture of foreign countries’, ‘Food circulation’ on television, Most content (‘Table etiquette’, ‘Simple cooking’, ‘Food sanitati n’, ‘Eating behaviors for health’, ‘Reasons for eating fruits and vegetables’, ‘Healthy snacks’) was learned from parents. The practice after nutrition education was higher in ‘Table etiquette’ (2.14), ‘Eating fruits and vegetables’ (2.07) than others compared with education experience. The most reason of non-practice on nutrition information was ‘Troublesome’. In ‘Nutrients for body’, a boy answered ‘Difficult for practice’ 20.0%, a girl answered ‘Difficult to understand’ 32.6%, showing a significant difference between the gender groups (p < 0.001). They remembered the ‘Nutrients for body’ (49.6%), ‘Food sanitation’ (44.5%) because of ‘important content’,‘Basic food preparation’ (40.6%), ‘Food culture of foreign countries’ (36.3%) because of ‘interesting content’, ‘Healthy weight loss’ (52.0%), ‘Eating behavior for health’ (44.5%) and ‘Healthy snacks’ (33.7%) because of ‘need for my health’.

Effect of Hydrogen Gas Ratio on the Characteristics of Pulsed DC-Magnetron Sputtered ITO Films in Amorphous/Crystalline Silicon Heterojunction Solar Cells

Kim, Sunbo,Jung, Junhee,Kim, YoungKuk,Le, Anh Huy Tuan,Ahn, Shihyun,Park, Jinjoo,Kim, Yongjun,Dao, Vinh Ai,Lee, Jaehyeong,Lee, Youn-Jung American Scientific Publishers 2017 Journal of Nanoscience and Nanotechnology Vol.17 No.5

<P>This study investigates the effect of hydrogen gas ratio [H-2/H-2+Ar] had on the structural, optical and electrical properties of ITO films for use in amorphous/crystalline silicon hetero-junction solar cells. The pulsed DC magnetron sputtered ITO films showed a higher optical transmittance for a hydrogen gas ratio of 3.2%. The lowest sheet resistance (43.12 Omega/square) and resistivity (3.25x10(-4) Omega.cm) were observed for ITO films where the hydrogen gas ratio was in the range from 1.31 to 3.22%. The Hall mobility of the ITO films decreased from 55.3 to 42.5 cm(2)/V.s with an increase in the hydrogen gas ratio from 1.31 to 3.2%. The surface morphology and crystallinity of films improved for the low hydrogen gas ratio while the characteristics of the ITO films deteriorated when the hydrogen ratio was higher than 3.2%. Then, we fabricated amorphous/crystalline silicon hetero-junction solar cells using ITO films for the front anti-reflection layer, and a hydrogen gas ratio of 3.22% resulted in a short circuit current density (J(sc)) of 38.17 mA/cm(2) and an efficiency of 19.02%.</P>

페놀계 활성탄소섬유 전극과 수용성 전해질을 사용하는 전기이중층 캐패시터의 비축전용량 특성

김태환,김정덕,김권일,안계혁,김종휘 한국공업화학회 1998 응용화학 Vol.2 No.1

For the electric double layer capacitors(ELDC) made of phenol based activated carbon fiber(ACF) electrodes and aqueous electrolytes, the specific capacitance characteristics has been investigated with respect to different specific surface area of electrodes and different kinds of aqueous electrolytes. Throughout charge-discharge cell tests, it has been shown that larger surface area of electrodes and higher ion mobility of electrolytes have better specific capacitances. Also, it has been found that 1200℃ heat treatment of the electrode is effective to improve the specific capacitance over 140F/g.

TLR4/NF-κB axis induces fludarabine resistance by suppressing TXNIP expression in acute myeloid leukemia cells

Huy, Hangsak,Kim, Tae-Don,Kim, Won Sam,Kim, Dong Oh,Byun, Jae-Eun,Kim, Mi Jeong,Park, Young-Jun,Yoon, Suk Ran,Noh, Ji-Yoon,Lee, Jungwoon,Lee, Kyoo-Hyung,Choi, Inpyo,Jung, Haiyoung Elsevier 2018 Biochemical and biophysical research communication Vol.506 No.1

<P><B>Abstract</B></P> <P>Overcoming drug resistance is one of key issues in treating refractory acute myeloid leukemia (AML). The Toll-like receptor 4 (TLR4) signaling pathway is involved in many aspects of biological functions of AML cells, including the regulation of pro-inflammatory cytokine products, myeloid differentiation, and survival of AML cells. Thus, targeting TLR4 of AML patients for therapeutic purposes should be carefully addressed. In this regard, we investigated the possible role of TLR4 as a regulatory factor against fludarabine (FA) cytotoxicity activity. Here, we identified the differential expression of TLR4 and CD14 receptors in AML cell lines and examined their relationship to FA sensitivity. We found that the stimulation of TLR4 with lipopolysaccharide (LPS) in a TLR4-expressing cell line, THP-1, increased cell viability under FA treatment condition and showed that TLR4 stimulation overcame FA sensitivity through the activation of NF-κB, which subsequently upregulated several anti-apoptotic genes. The inhibition of TLR4/NF-κB signaling could partially or completely reverse LPS-induced cell survival under FA treatment conditions. Interestingly, we found that the expression of thioredoxin-interacting protein (TXNIP), a well-known tumor suppressor, was induced by FA treatment; however, it was suppressed by LPS treatment. Furthermore, the expression level of TXNIP was critical for FA-induced cytotoxicity or LPS-induced FA resistance of THP-1 cells. Our data suggest that TXNIP plays an important role in FA-induced cytotoxicity and TLR4/NF-κB-mediated FA resistance of AML cells. Therefore, TXNIP may be a potential therapeutic target for AML treatment.</P> <P><B>Highlights</B></P> <P> <UL> <LI> THP-1 cells highly express the Toll-like receptor 4 (TLR4). </LI> <LI> THP-1 cells overcome fludarabine (FA)-induced cytotoxicity by LPS treatment. </LI> <LI> TLR4/NF-κB signaling regulates LPS-induced cell survival under FA treatment. </LI> <LI> TXNIP is crucial for FA-induced cytotoxicity and TLR4/NF-κB-mediated FA resistance. </LI> </UL> </P>

Physicochemical Characteristics of El Salvadoran Coffea arabica cv. Bourbon Coffee Extracts with Different Roasting Conditions

Yosub Kim,Eunkyung Kim,Tran Khac Huy,Jiwoo Kim,Yujihn Kwon,Seunghyup Lee,Ka-Young Song,Inyong Kim,Jung-Heun Ha,Youngseung Lee,Ki-Young Kim,Yoonhwa Jeong 한국식품영양과학회 2019 한국식품영양과학회 학술대회발표집 Vol.2019 No.10

Loss of EMP2 Inhibits Melanogenesis of MNT1 Melanoma Cells via Regulation of TRP-2

Enkhtaivan Enkhmend,Kim Hyun Ji,Kim Boram,Byun Hyung Jung,Yu Lu,Nguyen Tuan Minh,Nguyen Thi Ha,Do Phuong Anh,Kim Eun Ji,Kim Kyung Sung,Huy Hiệu Phùng,Rahman Mostafizur,Jang Ji Yun,Rho Seung Bae,이호,Kan 한국응용약물학회 2022 Biomolecules & Therapeutics(구 응용약물학회지) Vol.30 No.2

Melanogenesis is the production of melanin from tyrosine by a series of enzyme-catalyzed reactions, in which tyrosinase and DOPA oxidase play key roles. The melanin content in the skin determines skin pigmentation. Abnormalities in skin pigmentation lead to various skin pigmentation disorders. Recent research has shown that the expression of EMP2 is much lower in melanoma than in normal melanocytes, but its role in melanogenesis has not yet been elucidated. Therefore, we investigated the role of EMP2 in the melanogenesis of MNT1 human melanoma cells. We examined TRP-1, TRP-2, and TYR expression levels during melanogenesis in MNT1 melanoma cells by gene silencing of EMP2. Western blot and RT-PCR results confirmed that the expression levels of TYR and TRP-2 were decreased when EMP2 expression was knocked down by EMP2 siRNA in MNT1 cells, and these changes were reversed when EMP2 was overexpressed. We verified the EMP2 gene was knocked out of the cell line (EMP2 CRISPR/Cas9) by using a CRISPR/Cas9 system and found that the expression levels of TRP-2 and TYR were significantly lower in the EMP2 CRISPR/Cas9 cell lines. Loss of EMP2 also reduced migration and invasion of MNT1 melanoma cells. In addition, the melanosome transfer from the melanocytes to keratinocytes in the EMP2 KO cells cocultured with keratinocytes was reduced compared to the cells in the control coculture group. In conclusion, these results suggest that EMP2 is involved in melanogenesis via the regulation of TRP-2 expression.

PRR16/Largen Induces Epithelial-Mesenchymal Transition through the Interaction with ABI2 Leading to the Activation of ABL1 Kinase

( Gyeoung Jin Kang ),( Jung Ho Park ),( Hyun Ji Kim ),( Eun Ji Kim ),( Boram Kim ),( Hyun Jung Byun ),( Lu Yu ),( Tuan Minh Nguyen ),( Thi Ha Nguyen ),( Kyung Sung Kim ),( Hiệu Phùng Huy ),( Mostafizu 한국응용약물학회 2022 Biomolecules & Therapeutics(구 응용약물학회지) Vol.30 No.4

Advanced or metastatic breast cancer affects multiple organs and is a leading cause of cancer-related death. Cancer metastasis is associated with epithelial-mesenchymal metastasis (EMT). However, the specific signals that induce and regulate EMT in carcinoma cells remain unclear. PRR16/Largen is a cell size regulator that is independent of mTOR and Hippo signalling pathways. However, little is known about the role PRR16 plays in the EMT process. We found that the expression of PRR16 was increased in mesenchymal breast cancer cell lines. PRR16 overexpression induced EMT in MCF7 breast cancer cells and enhances migration and invasion. To determine how PRR16 induces EMT, the binding proteins for PRR16 were screened, revealing that PRR16 binds to Abl interactor 2 (ABI2). We then investigated whether ABI2 is involved in EMT. Gene silencing of ABI2 induces EMT, leading to enhanced migration and invasion. ABI2 is a gene that codes for a protein that interacts with ABL proto-oncogene 1 (ABL1) kinase. Therefore, we investigated whether the change in ABI2 expression affected the activation of ABL1 kinase. The knockdown of ABI2 and PRR16 overexpression increased the phosphorylation of Y412 in ABL1 kinase. Our results suggest that PRR16 may be involved in EMT by binding to ABI2 and interfering with its inhibition of ABL1 kinase. This indicates that ABL1 kinase inhibitors may be potential therapeutic agents for the treatment of PRR16-related breast cancer.

High-capacitance activated bio-carbons with controlled pore size distribution for sustainable energy storage

Kim, Yong Il,Lee, Yun Jung,Yoo, Jungjoon,Kim, Jong-Huy Elsevier 2019 Journal of Power Sources Vol.438 No.-

<P><B>Abstract</B></P> <P>Depletion of fossil-fuel energy resources creates a demand for sustainable energy technologies and therefore necessitates the development of sustainable energy storage devices with sustainable materials, eco-efficient synthetic methods, and robust cycle life. Electric double layer capacitors are potential candidates for sustainable energy storage because they usually employ carbon-based electrode materials with semi-permanent lifetimes and high powers. Although various carbon materials are commercially available, new methods are needed to produce eco-efficient synthesized carbon materials with high performances. Herein, we introduce an effective strategy that uses biomaterials as carbon sources and adopts a reusable KOH solution soaking method for the activation process to reduce KOH consumption, which includes a pore-size control process to enhance electrochemical performances. The obtained bio-carbons exhibit specific capacitances (160.6 and 151.2 F g<SUP>−1</SUP> in aqueous and organic electrolytes, respectively) superior to that of commercially available activated carbon (~80 F g<SUP>−1</SUP>), which is attributed to the synergetic effect between the pore-size-controlled activated carbon for efficient ion transport and the well-matched electrolyte. Our strategy provides a versatile method for the scalable fabrication of sustainable energy storage materials and is promising for the development of high-performance supercapacitors.</P> <P><B>Highlights</B></P> <P> <UL> <LI> •Activated bio-carbons for sustainable energy storage were prepared </LI> <LI> •Physical properties of the pore-size controlled materials were evaluated </LI> <LI> •Activated carbon electrodes were applied in electric double-layer capacitors </LI> <LI> •The electrodes showed excellent capacitance in aqueous and organic electrolytes </LI> <LI> •The large specific surface area and ion-matched pore size were key to performance </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

용접지단부 TIG처리에 의한 피로강도향상 및 피로특성

정영화,김익겸,남왕현,장동휘 강원대학교 산업기술연구소 2000 産業技術硏究 Vol.20 No.A

The 4-point bending tests have been performed in order to estimate the effect of TIG-dressing on fatigue strength and fatigue characteristics quantitatively for nonload-carrying fillet welded joints subjected to pure bending. As a result of fatigue tests, fatigue strengths of as-welded specimens have satisfied the grade of fatigue strength prescribed in specifications of korea, AASHTO and JSSC. Fatigue strength at 2 million cycles of TIG-dressing specimens have increased compared with as-welded specimens. As the result of beachmark tests, fatigue cracks occurred at several points, where the radius of curvature and flank angle in the weld bead toes were low, and grew as semi-elliptical cracks, then approached to fracture, As a result of finite element analysis, stress concentration factor in weld bead toes has closely related to the flank angle and radius of curvature, and between these, the radius of curvature has more largely mechanics approaches, the crack correction factor than flank angle. As a result of fracture mechanics approaches, the crack correction factor of test specimens has largely affected on stress gradient correction factor in case a/t is below 0.4 from the relations between stress intensity factor range estimated from FEM analysis and fatigue crack growth rate, fatigue life has been correctly calculated.

페놀계 활성탄소섬유 전극과 유기성 전해질을 사용하는 전기이중층 캐패시터의 비축전용량 특성

김태환,김정덕,안계혁,김종휘 한국공업화학회 1998 응용화학 Vol.2 No.1

For the electric double layer capacitors(ELDC) made of phenol based activated carbon fiber(ACF) electrodes and organic electrolytes, the specific capacitance characteristics has been investigated with respect to different specific surface area of electrodes and different kinds of organic electrolytes. Throughout charge-discharge cell tests, it has been found that larger surface area and larger pore diameter of electrodes contribute to increase the specific capacitance. Binary mixture of organic solvent with 1M-propylenecabonate(PC) and 1M-tetrahydrofuran(THF) for 1M-LiClO₄ electrolyte has a higher specific capacitance than single solvent of 1M-PC or mixed solvent with 1M-PC and 1M-diethylcabonate(DEC). Also, even though 1M-tetraethyl-amoniumperclorolate(1M-TEAPC) of organic electrolyte shows higher specific capacitance, it has longer charge time because of its lower ion mobility.