肝吸蟲症에 있어서 Praziquantel 投與 前後의 抗體價變動에 관한 硏究

李權海,嚴基善,林漢鍾 고려대학교 의과대학 1986 고려대 의대 잡지 Vol.23 No.3

The changes of antibody to adult worm of Clonorchis sinensis were studied using ELISA before and after treatment. Sera from 93 cases of confirmed human clonorchiasis were examined before treatment and at six months after treatment with a single dose of praziquantel 40 mg/kg bwt. Serum IgG level against C. sinensis (mean absorbance values at 488 nm) of 30 healthy controls from non-endemic area were 0.202±0.099, Sera of clonorchiasis patients showed significantly higher level of serum IgG (1.397±0.583) before treatment comparing with those of healthy controls. At after treatment the IgG levels were lower (0,858±0.408) than those of before treatment. At before treatment, the serum IgG level was highest in the group of very heavy infection (1.937±1.428), followed by heavy (1.860±0.297), moderate (1.491±0.579) and light (1.109±0.507) infection. The serum IgG level decreased significantly in heavy infection group (1.015±0.448) and in very heavy infection group (1.143 0.506) after treatment, then followed by moderate infection group (0.849±0.412) and light infection group (0.753±0.341). The egg discharge of thirty four out of ninty three clonorchiasis patients was negatively converted in stool examination and showed much decreased serum IgG level (0.718±0.356) as well as in the egg reducted fifty nine patients (0.943± 0.409). And the high antibody level groups showing the absorbance value higher than 1.50 (n=45) revealed more significant decrease of serum IgG level after treatment than the low antibody level group with less than 1.50. Conclusively, it was observed that serum specific IgG level was decreased at six months after treatment and the decreasing tendancy was more significant in higher E.P.G. group.

석탄폐석의 흡착능 개발 및 흡착제로의 활용방안 연구

김해숙,한동준,임재명,전은주,최용범,김병욱,강성환,신혜영 강원대학교 석재복합신소재제품연구센터 1997 석재연 논문집 Vol.2 No.-

본 연구는 폐기물의 형태로 현재 산과 계곡에 투기되어 있는 석탄페석을 이용하여 중금속 흡착과 난분해성 COD 및 색도제거 가능성을 검토하고, 간단한 열처리를 통한 흡착능 개발 실험을 위하여 수행되었다. 실험 결과 천연상태의 석탄폐석은 약 20∼30%의 중금속 흡착능을 지니고 있는 것으로 나타났으며, 탄화 공정인 간단한 열처리 만으로도 약 2 ∼ 5배의 흡착능 향상이 이루어졌다. 그리고 석탄폐석의 열처리 조건 변화에 따른 중금속 흡착능 실험에서는 500℃ 에서 6시간 반응시킨 것이 가장 우수하였다. 칼럼실험에 있어 기존의 입상활성탄 보다 처리효율이 저조하나 석탄폐석은 무가공 상태로도 약 30 ∼ 60%의 COD 및 색도를 제거할 수 있었다. 500℃에서 6시간 열처리된 폐석의 컬럼실험에서 생물학적 유출수의 색도 제거에 우수함을 알 수 있었으며, 중금속 및 COD제거에 있어서는 여과 속도에 따라 많은 차이를 보였다. 본 연구에서는 열처리 공정만 적용한 기초 실험이였으나, 석탄폐석의 흡착제 개발의 가능성을 알 수 있었으며, 활성화 공정을 적용할 경우 흡착능은 더욱 향상될 것으로 판단된다. This reaserch aims to remove the heavy metals, NBDCOD, and color using the coal waste. The expermental by heat treatment. was performed to advance the adsorption capacity. The results are as follows ; ⅰ) The coal waste had the adsorption capacity of heavy metals and the rates were in the range of 20 to 30 percents. ⅱ) The heat treatment was the optimum condition that the reaction time was 6 hours at 500 ℃. ⅲ) In the column experimental, non-treated coal waste removed the COD and color in the range of 20 to 60 percents. ⅳ) Heat-treated coal waste showed the high removal rate of the color in biological effluent, but heavy metal and COD removal rates were changed by the filteration rates.

일부 흡연 대학생의 지각된 스트레스와 흡연실태에 대한 상관관계 연구

강초록,권시내,권혜림,박수경,송인혜,오해인,이미지,한승아,황선아,김수지 이화여자대학교 간호과학대학 2003 이화간호학회지 Vol.- No.37

In spite of the seriousness of smoking harm has been developed these days. the increase of national smoking rate and that the people in the twenties are especially leading the rise of national smoking rate is an important issue of national health. Smoking of the university students can occur health problem and cause loss of manpower and expenses in their social activity period. So then the actual state for prevention of smoking and development of a program to prohibit smoking has to be seized urgently and starting with the study of the realities of university students, the effort to find a related fluent of smoking has to be studied. Related to this, the purpose of this study is to seize the general characteristics of smoking university students and to find out the relationship between perceived stress and smoking status among smoking university students. In addition, by collating the relationship between perceived stress and smoking status among smoking university students we have the purpose to furnish the basal data of stress care, the best way to cope with stress through group training and the plan for nursing implementation to decrease the smoking rate. For this study, a survey was conducted for 204 smoking university students of 13 universities in Seoul from 9th of May to 16th of May, 2003. The collected data was analyzed by t-test, Pearson Correlation and ANOVA in the statistical packages SPSS/PC. Major findings of this study are as follows; 1. Of the 204 respondents 85.4% of them were male and 14.6% of them were female. The average age of the sample was 23.19 years old and 41.8% of them were in senior, 21.4% in junior, 16.9% in sophomore, 19.9% in freshman grade. The major motivation to start smoking was 'because of curiosity'(33.8%) and the first smoking experience was at 'senior high school' (41.9%) and at 'college' (41.9%). 2 The highest scored stress factor of smoking university students were stresses about school work. 3. 72.7% had experience to quit smoking at least one or more times. Most of the reason to keep on smoking was 'short will to quit'(51.0%) and the smoking place was usually at 'school' (41.4%). Most respondents for the number ofsmoking friends were '5 people and above' (73.2%). 4. There was a negative relationship between the general characteristics and the entire perceived stress, however, there was a positive relationship between the general characteristics and the perceived stress in 4 categories which is 'sex distinction', 'major of study', 'residence form' and' inmate'. 5. There was a negative relationship between the general characteristics and the entire smoking status, however, there was a positive relationship between the general characteristics and the smoking status in 2 categories which is 'presence of hobby' and 'number of smoking friends'. 6. There was a negative relationship between the perceived stress and the smoking status. Through this study we have seized the relationship between the general characteristics, perceived stress and the smoking status of smoking university students. There was a positive relationship between some of the general characteristics with the perceived stress and the smoking status of smoking university students. Also there was a negative relationship between the perceived stress and the smoking status.

Effects of Different Types of Isometric Hip Contraction on Gluteus Medius and Tensor Fasciae Latae Activity During Squat Exercises

Hae rim Han,Jeong ah Kim,One bin Lim,Heon seock Cynn,Chung hwi Yi 한국전문물리치료학회 2015 한국전문물리치료학회지 Vol.22 No.3

Hip muscle activation and strengthening exercise programs are often used to prevent and treat various lower extremity injuries. Common exercise programs include squat exercises. The purposes of this study were to investigate gluteus medius (GMED) and tensor fasciae latae (TFL) muscle activity, and to assess the GMED/TFL ratio during squat exercises involving different isometric hip contraction conditions. Different types of isometric hip contraction were standard squat without hip contraction, squats with isometric hip adduction, and squats with isometric hip abduction. Twenty (10 males and 10 females) healthy subjects (23.7±2.8 years old) were recruited. Subjects performed the squat exercises with the back supported by a wall and knees flexed to 60°. Surface electromyography (EMG) was used to measure GMED and TFL activity. One-way repeated analysis of variance was used to compare GMED and TFL muscle activity and the GMED/TFL ratio. GMED and TFL EMG activity was significantly higher during squats with isometric hip adduction and abduction compared with the standard squat without hip contraction (p<.05). Between the isometric hip adduction and abduction contraction conditions, only the TFL EMG activity was significantly higher during squats with isometric hip adduction than isometric hip abduction (p<.05). The GMED/TFL ratio was significantly higher during squats with isometric hip adduction than isometric hip abduction (p<.05). Squats with isometric hip adduction and abduction improved GMED and TFL muscle activity. Furthermore, the GMED/TFL ratio was higher during isometric hip adduction than isometric hip abduction. Our data indicate that squat exercises involving isometric hip adduction enhance GMED muscle activity.

Serological Survey of Major Avian Viral Diseases Related with Egg Productionin Commercial Chicken Flocks in Korea

hae sun jang,Hae-Rim Lee,구본상,Eun-Ok Jeon,Moo-Sung Han,Kyung-Cheol Min,Seung-Baek Lee,Yeonji-Bae,Sun-Hyung Cho,Jong-Suk Mo,Jong-Nyeo Kim,모인필 한국가금학회 2014 韓國家禽學會誌 Vol.41 No.3

While use of mass rearing systems improved poultry production, chances of exposing to contagious diseases have been increased, making flocks more vulnerable to diseases. Diseases of interest which affects egg production adversely include Low pathogenic avian influenza (LPAI), Infectious bronchitis (IB), Avian meta-pneumoviral infection (aMPV) and Egg drop syndrome’76 (EDS’76). This report collected and analyzed 5,385 serum samples, which were collected from 1,330 different chicken flock, provided by Chungbuk National University, Avian Disease Laboratory at 2009. Serums were analyzed based on rearing stages; 0∼1.3weeks (wks) (maternal antibody period), >1.3∼3 wks (starting period), >3∼10 wks (growing period), >10∼22 wks (developing period), >22∼40 wks (peak laying period), >40∼60 wks (late laying period) and over 60 wks (post-molting period). Results showed the 99.7% of the tested flocks were immunized against ND and73.8%, 97.1%, 78,2% and 78% of the flocks were immunized against other 4 agents (LPAI, IB, EDS’76, aMPV). Maternal antibody was transferred to enough quantity for NDV. Generally, antibody titers which were developed at 22 weeks were stabilized permanently for life. In case of IB and aMPV, infection titer emerged as early as 10 weeks and the titer was increased from 99.4% to 100% for life. EDS76 showed increase in titers, reflecting decreased frequency of vaccination programs. Overall, this study displayed general trends of major viral disease in layers, but considering the trend of development of preventive measures and evolution of pathogens, conducting serological surveys on a regular basis is important.

Epidemiological Studies of Avian Paramyxovirus Type 4 and 6 in Commercial Chicken Flocks in Korea

Hae Rim Lee,Bon-Sang Koo,Eun-Ok Jeon,Moo-Sung Han,Kyung-Cheol Min,Seung Baek Lee,Yeonji Bae,Kang-Seuk Choi,Jeong-Hwa Shin,In-Pil Mo 한국가금학회 2013 韓國家禽學會誌 Vol.40 No.4

Case Repor : Necrotic enteritis in a captive mute swan (Cygnus olor) in the breeding season

( Hae Rim Lee ),( Bon Sang Koo ),( Eun Ok Jeon ),( Moo Sung Han ),( Kyung Cheol Min ),( Seung Baek Lee ),( Yeon Ji Bae ),( Jung Ho Kim ),( In Pil Mo ) 한국가축위생학회 2014 韓國家畜衛生學會誌 Vol.37 No.2

A captive mute swan (Cygnus olor) in the brooding period was found dead without any specific signs. On necropsy, the entire digestive tract was severely necrotized with loosely adherent pseudo membranes, and Clostridium perfringens (CP) colonies isolated from the intestinal contents were identified as CP type A by polymerase chain reaction. Microscopically, the intestine and the liver were necrotized and intralesional bacterial clusters were observed. In this case, there were no other mortalities, so the condition of a single bird, in particular, stress from incubation effort, could act as the predisposing factor for necrotic enteritis. In this study, we report a unique case of necrotic enteritis associated with incubation in a captive mute swan.

Epidemiological Studies of Avian Paramyxovirus Type 4 and 6 in Commercial Chicken Flocks in Korea

Lee, Hae Rim,Koo, Bon-Sang,Jeon, Eun-Ok,Han, Moo-Sung,Min, Kyung-Cheol,Lee, Seung Baek,Bae, Yeonji,Choi, Kang-Seuk,Shin, Jeong-Hwa,Mo, In-Pil The Korean Society of Poultry Science 2013 韓國家禽學會誌 Vol.40 No.4

Avian paramyxovirus (APMV) type 4 and 6 were isolated during an avian influenza (AI) surveillance program of wild birds. This study also conducted experimental infection of wild-bird-origin APMV type 4 and 6 in specific pathogen free (SPF) chickens to study pathogenicity and transmission within domestic flocks. In addition, serological prevalence data of APMV type 4 and 6 in domestic fowls was conducted with chicken sera collected from 2007 to 2009 in order to understand infection status. The results of the animal experiment showed that APMV type 4 and 6 had the ability to infect chickens with sero-conversion and to transmit the virus from infected birds to contacted birds, but showed low pathogenicity. Serological tests revealed that APMV type 4 was widespread in the poultry industry, especially in layer flocks, but the positive rate for APMV type 6 was very low. This study concluded that wild bird-origin APMV type 4 and 6 could infect the chickens by inter-species transmission and the seroprevalence of APMV type 4 was quite high in Korean poultry. However, since almost all the chicken flocks had a high level of antibody titer against APMV type 1, there was possibility of cross reaction between APMV type 1 and 4, which made the interpretations more complicated. In order to understand infection status in the natural environment, additional study is necessary regarding the seroprevalence of APMV type 4 and 6 in the wild bird population.

Musculoskeletal complications in patients with diabetes mellitus

Jong Han Choi,Hae-Rim Kim,Kee-Ho Song 대한내과학회 2022 The Korean Journal of Internal Medicine Vol.37 No.6

Musculoskeletal conditions are common in patients with diabetes. Several musculoskeletal disorders are viewed as chronic complications of diabetes because epidemiological studies have revealed high correlations between such complications and diabetes, but the pathophysiological links with diabetes remains unclear. Genetic predispositions, shared risk factors, microvascular impairments, progressive accumulation of advanced glycation end-products, and diabetic neuropathy may underlie the development of musculoskeletal disorders. Musculoskeletal complications of diabetics have received less attention than life-threatening microvascular or macrovascular complications. Here, we review several diabetic musculoskeletal complications with a focus on the clinical importance of early recognition and management, which would improve quality of life and physical function.

Serological Survey of Major Avian Viral Diseases Related with Egg Production in Commercial Chicken Flocks in Korea

Jang, Hae-Sun,Lee, Hae-Rim,Koo, Bon-Sang,Jeon, Eun-Ok,Han, Moo-Sung,Min, Kyung-Cheol,Lee, Seung-Baek,Bae, Yeonji,Cho, Sun-Hyung,Mo, Jong-Suk,Kim, Jong-Nyeo,Mo, In-Pil The Korean Society of Poultry Science 2014 韓國家禽學會誌 Vol.41 No.3

While use of mass rearing systems improved poultry production, chances of exposing to contagious diseases have been increased, making flocks more vulnerable to diseases. Diseases of interest which affects egg production adversely include Low pathogenic avian influenza (LPAI), Infectious bronchitis (IB), Avian meta-pneumoviral infection (aMPV) and Egg drop syndrome'76 (EDS'76). This report collected and analyzed 5,385 serum samples, which were collected from 1,330 different chicken flock, provided by Chungbuk National University, Avian Disease Laboratory at 2009. Serums were analyzed based on rearing stages; 0~1.3weeks (wks) (maternal antibody period), >1.3~3 wks (starting period), >3~10 wks (growing period), >10~22 wks (developing period), >22~40 wks (peak laying period), >40~60 wks (late laying period) and over 60 wks (post-molting period). Results showed the 99.7% of the tested flocks were immunized against ND and73.8%, 97.1%, 78,2% and 78% of the flocks were immunized against other 4 agents (LPAI, IB, EDS'76, aMPV). Maternal antibody was transferred to enough quantity for NDV. Generally, antibody titers which were developed at 22 weeks were stabilized permanently for life. In case of IB and aMPV, infection titer emerged as early as 10 weeks and the titer was increased from 99.4% to 100% for life. EDS76 showed increase in titers, reflecting decreased frequency of vaccination programs. Overall, this study displayed general trends of major viral disease in layers, but considering the trend of development of preventive measures and evolution of pathogens, conducting serological surveys on a regular basis is important.