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        Skin entrance dose for digital and film radiography in Korean dental schools

        Cho, Eun-Sang,Choi, Kun-Ho,Kim, Min-Gyu,Lim, Hoi-Jeong,Yoon, Suk-Ja,,Kang, Byung-Cheol 대한구강악안면방사선학회 2005 Imaging Science in Dentistry Vol.35 No.4

        Purpose : This study was aimed to compare skin entrance dose of digital radiography with that of film radiography and to show the dose reduction achievement with digital systems at 11 dental schools in Korea. Materials and Methods : Forty six intraoral radiographic systems in 11 dental schools were included in this study. Digital sensors were used in 33 systems and film was used in 13 systems. Researchers and the volunteer visited 11 dental schools in Korea. Researchers asked the radiologic technician (s) at each school to set the exposure parameters and aiming the x-ray tube for the periapical view of the mandibular molar of the volunteer. The skin entrance doses were measured at the same exposure parameters and distance by the technician for each system with a dosimeter (Multi-O-Meter : Unfors instruments, Billdal, Sweden). Results : The median dose was 491.2 μGy for digital radiography and 1,205.0 μGy for film radiography. The skin entrance dose digital radiography was significantly lower than that of film radiography (p<0.05). Conclusion : Fifty-nine percent skin entrance dose reduction with digital periapical radiography was achieved over the film radiography in Korean dental schools.

      • SCIESCOPUSKCI등재

        Three-Dimensional Porous Collagen/Chitosan Complex Sponge for Tissue Engineering

        Kim, Sung Eun,Cho, Yong Woo,Kang, Eun Jung,Kwon, Ick Chan,Lee, Eunhee Bae,Kim, Jung Hyun,Chung, Hesson,Jeong, Seo Young The Korean Fiber Society 2001 Fibers and polymers Vol.2 No.2

        A three-dimensional, porous collagen/chitosan complex sponge was prepared to closely simulate basic extracellular matrix (ECM) constitutes, collagen and glycosaminoglycan. The complex sponge was prepared by a lyophilization method and had the regular network with highly porous structure, suitable for cell adhesion and growth. The pores were well interconnected, and their distribution was fairly homogeneous. The complex sponge was crosslinked using 1-ethyl-3-(3-dimethyl aminopropyl) carbodiimide (EDC) and N-hydroxysuccinimide (NHS) to increase its boilogical stability and enhance its mechanical properties. The crosslinking medium has a great effect on the inner structure of the sponge. The homogeneous, porous structure of the sponge was remarkably collapsed in an aqueous crosslinking medium. However, the morphology of the sponge remained almost intact in a water/ethanol mixture crosslinking milieu. Mechanical properties of the collagen/chitosan sponge were significantly enhanced by EDC-mediated crosslinking. The potential of the sponge as a scaffold for tissue engineering was investigated using a Chinese hamster ovary cell (CHO-K1) line.

      • 컴퓨터 시뮬레이션을 통한 치어사육용 다단계 배양시스템의 개발 가능성 탐색

        정은수,조덕제,이정석,조만기 동서대학교부설연구소 1998 연구소 논문집 Vol.3 No.-

        It was researched that the possibility for developing multistage culture system to cultivate larvae by computer simulation with basic experiments. This culture system was composed of 3 stages. Chlorella sp. at the 1st stage are being supplied to the rotifer(Brachionus plicatilis) at 2nd stage, and the rotifer are bing feeded to larvae at the 3rd stage. In this study, Chlorella sp. were cultivated by batch culture to search for the possibility of continuous feeding rate Chlorella sp., ???????? and ??(cells/hㆍrotifer) in the multistage culture system, then the change of the rotifer concentration at 2nd stage was simulated by computer. The required amount of rotifer for the growth of larvae was also increased as the increase of the length of larvae. On the 9th day of the culture, the rotifer uptake rate of larvae was 250(cells/dayㆍlarvae). Based on these basic experiments and results. It was suggested that the possibility of multistage culture system to cultivate larvae with continuous feeding of Chlorella sp. and rotifer.

      • 개의 아토피 피부염에 대한 Leflunomide의 임상적 적용 1례

        홍은지,윤기영,서경원,최호정,정성목,송근호,조종기,박성준 忠南大學校 獸醫科大學 附設 動物醫科學硏究所 2012 動物醫科學硏究誌 Vol.19 No.1

        A Shih-tzu(8-year-old, castrated male) was referred to the Veterinary Medical Teaching Hospital of Chungnam National University with the history of relapsing pruritus, recurrent dermatitis. On the physical examination, generalized erythema, otitis externa, alopecia and lichenification were observed. Using Favrot's criteria for diagnishing atopic dermatitis, 7 criteria were satisfied out of 8 criteria. After treatment for infection, intradermal skin test was performed(positive allergen : Df, Dp). And then immunotherapy was performed, but clinical signs were not getting better. Next treatment of glucocorticoid shown little improvement of clinical signs, and adverse effect(diarrhea) was shown after cyclosporine application. So application of leflunomide which is used for human atopic dermatitis treatment in some case was planned. After 6 months of application of leflunomide, clinical signs were decreased gradually.

      • 고등어 및 정어리 선어의 휘발성성분

        조우진,김훈,정연정,이영미,정은정,차용준 창원대학교 생활과학연구소 2002 생활과학연구 Vol.- No.6

        This study was conducted to identify volatile compounds, associating with quality deterioration, which may play roles as indicators for quality assessment in fresh mackerel and sardine. Volatile compounds were analyzed by liquid liquid continuous extraction(LLCE)/GC/MSD methods. A total of 83 and 81 volatile compounds were detected in fresh mackerel and sardine, respectively, and these compounds were mainly composed of aldehydes(12 in raw mackerel, 11 in raw sardine), ketones(7, 4), alcohols(15, 14), esters(1, 3), aromatic compounds(13, 15), terpenes(5, 7), S-containing compounds(2, 2), hydrocarbons(13, 11) and miscellaneous compounds(2, 1). Most of compounds including carbonyls, alcohols, aromatic compounds and hydrocarbons were derived from lipid oxidation, and some compounds were detected from microbial degradation. It was supposed that LLCE method was proper to seek indicators for quality assessment in fresh mackerel and sardine, because of various volatile compounds derived from nonthermal lipid oxidation.

      • An Analysis of Diplomatic Relations between the Republic of Korea and the Republic of Kazakhstan, and Its Prospects

        Cho,Eun-Jeong,Kim,German N 고려대학교 러시아 CIS연구소 2012 Acta Russiana Vol.4 No.-

        В 2012-ом году Республика Корея и Республика Казахстан отмечают 20- летие установления дипломатических отношений. В данной статьи рассматривается, какие внешние и внутренние детерминанты оказывали решающие влияние на создание, применение и дополнение внешней политики Республики Корея в отношений Казахстана с того момента, когда обе страны установили дипломатических отношений. Теория процесса принятия решений внешней политики, которая развивалась в основном в рамках послевоенной американской политологии с середины 20 века, показывает, что в отличии от традиции "реалистической" теории в современном мире "разные" факторы через "сложный и многослойный" процесс оказывают влияние на создание и применение дипломатической политики, и её результаты имеют обратную связь и принимаются во внимание в последующем потоке деятельности. В течение 20 лет дипло-матических связей южнокорейско казахстанские отношения развивались через три периода. Это во-первых, период образования отношений с момента установления дипломатических отношений в начале 90-ых годов до азиатского финансового кризиса в конце 90-х годов, во-вторых, период развития связей на основе экономического и ресурсного сотрудничества с начала 2000-ых годов до прихода к власти нынешней администрации в 2007 году и, в-третьих, период диверсификации отношений не только в экономическом, но и в политическом, культурном, социальном секторах с прихода к власти нынешней администрации Ли Мён Бака в 2008 году до сегодняшнего дня. В данной статьи рассматривается, какие именно внешние и внутренние факторы во вышеуказанных 3 периодах сыграли главную роль во принятии дипломатического курса Республики Корея в отношении Казахстана и намечаются, какие особенности существуют в Южнокорейско-Казахстанских отношениях во время развития дипломатических отношений обеих стран.

      • C 프로그램에서 객체 식별을 통한 C++ 클래스로의 재구성

        조은숙,신현정,류성열 崇實大學校 生産技術硏究所 1995 論文集 Vol.25 No.1

        대부분의 소프트웨어 시스템들은 C, Fortran, 그리고 COBOL과 같은 절차 중심 언어로 개발되었다. 이러한 언어들은 시스템에 대한 계층적 표현을 제공하지 못하기 때문에 시스템을 이해하고 유지 보수하고 재사용하기 어렵다. 이러한 어려움을 극복하기 위해서는 Ada의 패키지나 C++클래스로 재구성하는 방법이 있는데 Ada의 패키지로 재구성하는 경우에 있어서는 패키지간의 상속성에 대한 표현을 할 수가 없다.본 논문에서는 C언어로 작성된 프로그램을 입력으로 받아서 수신 기반 객체 식별을 통해서 C++클래스로 재구성하는 방법을 제안하고자 한다. 수신 기반 객체 식별을 통한 재구성 방법을 위한 도구로서 프로그램 종속성 그래프를 사용한다. 프로그램 종속성 그래프는 클래스를 구성하는 데 사용된다. 본 논문에서 제안한 재구성 기법을 통해서 프로그램의 모듈화, 추상화, 정보 은닉을 높이고 개체 지향 프로그래밍 언어인 C++로의 변환을 용이하게 하도록 한다.

      • 니세틸 정(아세틸-엘-카르니틴 500 mg)에 대한 뉴로세틸 정의 생물학적 동등성

        조혜영,김은아,정현철,심영순,임동구,오인준,문재동,이용복 전남대학교 약품개발연구소 2001 약품개발연구지 Vol.10 No.-

        Acetyl-L-carnitine (ALC), an endogenous component of the L-carnitine family, is naturally occurring molecule synthesized from L-carnitine (LC) by carnitine acetyl transferase. ALC has been shown to improve the cognitive performance of patients suffering from dementia of the Alzheimer's type and proposed for treating Alzheimer's disease in pharmacological doses. The purpose of the present study was to evaluate the bioequivalence of two ALC tablets, Nicetiler^TM (Dong-A pharmaceutical Co., Ltd.) and Neurocetil^TM (Kyung-Dong Pharmaceutical Co., Ltd.), according to the guidelines of Korea Food and Drug Administration. Twenty six normal male volunteers, 22.80±2.76 year in age and 63.07 7.98㎏ in body weight, were divided into two groups and a randomized 2×2 cross-over study was employed. After one tablet containing 500㎎ of ALC was orally administered, blood was taken at predetermined time intervals and the concentrations of ALC in serum were determined using HPLC with fluorescence detector. Because of the presence of endogenous ALC, the calibration was performed using dialyzed serum. Pharmacokinetic parameters such as AUC_t, C_max and T_max were calculated and ANOVA was utilized for the statistical analysis of the parameters. The results showed that the differences in AUC_t, C_max and T_max between two tablets were 2.72%, -0.65% and -8.42%, respectively, when calculated against the Nicetile^TM tablet. The powers (1-β) for AUC_t and C_max were 94.87% and 87.17%, respectively. Minimum detectable differences (Δ) at α=0.05 and 1-β=0.8 were less than 20% (e.g., 15.58% and 19.16% AUC_t and C_max, respectively). The 90% confidence intervals were within ±20% (e.g., -11.84∼6.41 and -10.57∼11.88 for AUC_t and C_max, respectively). Two parameters met the criteria of KFDA for bioequivalence, indicating that Neurocetil^TM tablet is bioequivalent to Nicetile^TM tablet.

      • 피부 병변을 동반한 악성조직구증 1예

        조은택,박용관,김진호,강정원,천영욱,전익섭,박유환,전춘해 조선대학교 1995 The Medical Journal of Chosun University Vol.20 No.1

        Malignant histiocytosis, originally described in 1939 as histiocytic medullary reticulosis by Scott and Robb-Smith, is a rare histiocytic proliferative disorder that often shows an acute onset and used to progress to death within a few months. This disorder characterized clinically by fever, generalized weakness, lymphadenopathy and hepatosplenomegaly, and shows a variable range of pancytopenia. Extranodal involvement is common, with an incidence ranging from 50% to as high as 90%, skin involves8ment was noted in 10% to 15%. Typical skin lesions were mainly founded in extremity. i.e. erythematous papule and nodule occasionally become to necrosis and ulceration. We experienced one case of malignant histiocytosis in a 46-years-old female. The major clinical findings are fever, malaise, hepatosplenomegaly and erythematous skin lesion. In the laboratory study, pancytopenia is noted on the peripheral blood. And also aggregation of many atypical histiocytes were shown on skin and bone marrow biopsy. So we reported one related case with malignant histiocytosis as well as reviewing literature .

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