원위 대퇴골의 고립성 골연골종에서 발생한 속발성 연골 육종 1례 보고

정필현,황장수,강석,김용민,오형호,채동주,김종필 동국대학교 경주대학 1996 東國論集 Vol.15 No.-

연골육종은 비교적 서서히 자라며 늦게 전이하는 악성 연골 종양으로 알려져 있다. 골 연골종에서 발생한 속발성 연골육종은 발생빈도는 드물며 타부위로의 전이가 적고 악성도가 낮은 경우가 많아 적합한 수술적 치료로서 좋은 예후를 보이는 것으로 보고되고 있다. 본 동국대학교 정형외과학 교실에서는 우측 대퇴골 원위부 골간단부에 생긴 고립성 골 연골종에서 이차적으로 발생한 연골육종을 치험한 바 문헌고찰과 함께 보고하는 바이다. A case of Secondary Chondrosarcoma Arising from Solitary Osteochondroma of the Distal Femur Department of Orthopaedic Surgery, College of Medicine, DongGuk University Phil Hyun Chung M.D., Jung Su Hwang M.D., Suk Kang M.D., Yang Mln Kim M.D., Hyung Ho Oh M.D., Dong Ju Chae M.D., Jong Pil Kim M.D. Chondrpsarcoma is a malignant cartilage-forming tumor that grows slowly and metastasis of this tumor occurs in late stage. Secondary chondrosarcomas arising from a solitary osteocartilaginous exostosis are rare and those have a better prognosis than other chondrosarcomas, and they rarely metastasize. We present our experience with a case of secondary chondrpsarcoma arising in solitary osteochondroma of distal metaphysis of right femur with clinical details.

한국인 직무 스트레스 측정도구의 개발 및 표준화

장세진,고상백,강동묵,김성아,강명근,이철갑,정진주,조정진,손미아,채창호,김정원,김정일,김형수,노상철,박재범,우종민,김수영,김정연,하미나,박정선,이경용,김형렬,공정옥,김인아,김정수,박준호,현숙정,손동국 大韓産業醫學會 2005 대한직업환경의학회지 Vol.17 No.4

Background and Purposes: Over the past three decades, numerous studies performed in Korea have reported that job stress is a determinant risk factor for chronic diseases and work disability. Every society has its own culture and occupational climate particular to their organizations, and hence experiences different occupational stress. An occupational stress measurement tool therefore needs to be developed to estimate it objectively. The purpose of this study is to develop and standardize the Korean Occupational Stress Scale (KOSS) which is considered to be unique and specific occupational stressors in Korean employees. Subjects and Methods: Data were obtained from the National Study for Development and Standardization of Occupational Stress (NSDSOS Project: 2002-2004). A total of 12,631 employees from a nationwide sample proportional to the Korean Standard Industrial Classification and the Korean Standard Occupational Classification were administered. The KOSS was developed for 2 years (2002-2004). In the first year, we collected 255 items from the most popular job stress measurement tools such as JCQ, ERI, NIOSH and OSI, and 44 items derived from the a qualitative study (depth interview). Forty-three items of KOSS, in the second year, were retained for use in the final version of the KOSS by using Delphi and factor analysis. Items were scored using conventional 1-2-3-4 Likert scores for the response categories. Results: We developed eight subscales by using factor analysis and validation process: physical environment (3 items), job demand (8 items), insufficient job control (5 items), interpersonal conflict (4 items), job insecurity (6 items), organizational system (7 items), lack of reward (6 items), and occupational climate (4 items). Together they explained 50.0% of total variance. Internal consistency alpha scores were ranged from 0.51 to 0.82. Twenty-four items of the short form of the KOSS (KOSS-SF) were also developed to estimate job stress in the work setting. Because the levels of the subscales of occupational stress were gender dependent, gender-specific standard norms for both the 43-item full version and the 24-item short form using a quartile for the subscales of KOSS were presented. Conclusion: The results of this study suggest that KOSS might be an appropriate measurement scale to estimate occupational stress of Korean employees. Further and more detailed study needs to be conducted to improve the validity of this scale.

솔-젤공정에 의한 한외알루미나 여과막의 기공보정에 관한 연구

채만병,조원준,정은정,이진휘,서동호 서울産業大學校 1996 논문집 Vol.44 No.1

서로 다른 입자 크기의 3층 구조를 갖는 튜브 형태의 한외 알루미나 분리막은, 일반적으로 제조공정중 분리층에 결손부분이 발생하기 때문에 낮은 선택도 및 제거율을 보인다. 이와같은 결손부분을 보정하기위하여 습도조절에 의한 선택적 적심(alternative wetting by controlled humidity)을 한 수 colloidal silical 솔을 적용하여 처리하고 특성을 평가 하였다. Sealing처리한 분리막에 대한 누수여부를 평가하기 위하여 3가지의 염료로 조사하였고, 보정전분리막과 보정후분리막에 대한 SEM, 액체으 투고도, 선택도 및 P.E.G./물 혼합물의 제거율을 측정하였다. P.E.G 2000, 12000 및 35000에 대한 제거율은 각각 약 0.6, 18 및 17% 향상된 결과를 보였으나 colloidal silica 솔의 deposition에 기인하여 투과율의 감소는 77%였다. 이상의 결과에서 보면 습도조절에 의한 선택적 적심법은 비록 deposition에 의한 문제점을 내포하고 있으나 액체분리를 위한 알루미나 한외여과막의 보정에 효과적인 방법이다. The 3-layer type alumina membrane consisting of different pore size shows the decreased selectivity and rejection because of cracks in the separation layer generally occurred during the manufacturing process. To modify these cracks, the colloidal sol is applied by sol-gel process after treating by alternative wetting method using controlled humidity(Alternative Wetting Method by controlled humidity) and evaluated the characteristics. For the evaluation of the leakage for the sealed membrane, the sealed membranes were tested by 3 kinds of dyes. For the comparing of native and modified membranes, the modified membranes for the cracks treated by Alternative Wetting Method by controlled humidity were also tested by SEM, permeability by liquid equipment, selectivity and rejection of the P.E.G./water mixtures. The results showed that the rejections were increased ca. 0.6, 18 and 17 % for the P.E.G. polyethyleneglycol 2000, 12000 and 35000 individually. The permeabilities are decreased, however, 77% for the pure water caused by deposition of colloidal silica sol after caulking. In conclusion, the Alternative Wetting Method by humidity control had the effect for the modification of ultrafiltration alumina membrane for separation of liquids and gases, though having problem of deposition.

톨루엔을 포함한 유기용제의 직업적 폭로로 인한 신경내분비계 영향

이채언,이종태,정의화,손혜숙,문덕환,전진호,강정학,이창희,김휘동,김종한,정귀옥 大韓産業醫學會 1995 대한직업환경의학회지 Vol.7 No.2

Long term occupational exposure to solvent mixtures may cause adverse effects to the central nervous system with neurobehavioral symptoms. And some organic slovents have been suggested to cause impairment of tuberoinfundibular dopaminergic activity and neurochemical mechanisms controlling pituitary secretion. For the purpose of assessing neuroendocrine effects in occupational solvents exposure, hormonal study settings (shoes-manufacturing industry & fishing products industry) and compared with nonexposed controls(33 men, 85 women). Male workers exposed to solvent mixtures had significantly lower plasma level of follicle-stimulating hormone(FSH) than nonexposed male controls. While female workers exposed to solvent mixtures had significantly lower plasma levels of growth hormone(GH), and thyroid-stimulating hormone(TSH) than nonexposed female controls. The results of significant decrease in plasma concentrations of pituitary hormones(FSH, GH, and TSH) in workers exposed solvent mixtures indicate that occupational exposure to solvent mixtures may induce neuroendocrine effects through an effect on hypothalamic pituitary axis.

심혈관 위험요인과 청력역치의 상관성

조영채,이태용,이동배,정성필,김수영 大韓産業醫學會 1998 대한직업환경의학회지 Vol.10 No.2

To investigate the effects of cardiovascular risk factors on hearing loss, hearing threshold and cardiovascular risk factors such as blood pressure, hematologic values, and serum lipid levels of 3,827 persons who visited the Health Center of a University Hospital in Kumi for health examination from January 1, 1995 to July 31, 1997 were analysed. The results were summarized as follows; 1. Hearing threshold was shifted highly in both sex groups with age increased. Smoking did not influence increase of hearing loss, but drinking alcohol amount increased the hearing threshold when sex was adjusted. The most highly increased hearing threshold showed among farmers group, but next was blue collars group. Hearing threshold increasing basis with BMI increased. 2. Systolic and diastolic blood pressure and hematocrit value increased the hearing threshold in both sex groups, but hemoglobin value did not related to the hearing threshold. 3. Total cholesterol, LDL-cholesterol, triglyceride, and atherosclerosis index were significantly increased with the grade of hearing loss increased, when age was adjusted. 4. In the logistic regression analysis, the atherosclerosis index, age, and hematocrit value revealed risk factors which contributed in that orders, though the values were small they showed statistical significaces, but the risks were lowered when hemoglobin values increased, in both sex groups. Consequently, hyperlipidemia was significantly related to the hearing loss when age was adjusted.

통풍성 관절염의 임상적 고찰

윤채중,정승문,김영학,김동규,허광식,김태원,배학연,정종훈,이승일,김평남 朝鮮大學校 附設 醫學硏究所 1997 The Medical Journal of Chosun University Vol.22 No.2

통풍은 Purine 대사의 이상으로 발생하는 질환으로, 고뇨산혈증인 사람의 전부가 통풍으로 발현되지 않고 증상의 출현 양상이 다양하여 진단과 치료에 주의가 필요하며, 조기에 적절한 조치를 한다면 충분히 조절이 가능한 질환이다. 본대학 내과학교실에서는 통풍으로 치료한 32명의 환자에서 임상양상, 병력과 검사소견을 분석하여 다음과 같음 결과를 얻었다. 1. 32명 모두 남자이며, 최초 발병 시기는 24세에서 72세로 평균 43.8±11.9세이었으며, 30대에서 40대까지가 19명(59.4%)으로 대부분을 차지하였다. 내원 당시 나이는 27세에서 75세까지로 평균 52.3±10.4세였으며, 내원시 까지 평균 유병기간은 8.5±6.8년으로 나타났다. 2. 동반 질환으로는 고지혈증 12례, 신장질환 10례, 고혈압 12례, 비만 8례, 당뇨 2례 등이었다. 3. 이환된 관절은 단관절 침범이 19례(59.4%), 다관절 침범이 13례 이었으며, 최초 이한된 관절은 족무지 중족골지골 관절로 19례(59.4%)로 가장 많았고, 통풍 결절은 20례(62.5%)에서 관찰되었으며, 유병기간이 10년 이상된 12례중 11례 (91.7%)에서 결절이 관찰되었다. 4. 평균 혈중 요산치는 9.17±1.75 ㎎/dl이었으며, 8.0 ㎎/dl에서 9.9 ㎎/dl 사이가 19명으로 전체의 59.4%를 차지하였다. Objective: The gout is a heterogeneous group of diseases resulting from tissue deposition of monosodium urate or uric acid crystals from extracellular fluids supersaturated with respect to this end product of human purine metabolism. The clinical manifestations are such as hyperuricemia, gouty arthritis, gouty nephropathy, uric acid nephrolithiasis. We analyze of clinical manifestations and associated factors in gout. Method: We have reviewed the medical records, radiologic findings and clinical results of thirty-two patients admitted at our department from April 1996 to July 1997. Result: 1) All patients were male. The mean age at initial attack was 43.8 years old, ranging from 24 to 72 years old. 2) The mean level of serum uric acid was 9.17mg/dl on admission. 3) The first metatarsopharyngeal joint was involved in 19 cases (59.4%). Tophus was observed in 20 cases (62.5%). 4) Hyperuricemia was associated with hypertension, obesity, nephrolithiasis and hyperlipidemia.

음주운전 처벌 강화법 실시전후에 따른 교통사고 발생양상변화

안정태,이동배,조영채,박암 충남대학교 의과대학 지역사회의학연구소 1992 충남의대잡지 Vol.19 No.1

In order to compare the characteristics of traffic accident trends before and after the amendment of The Road Traffic Law, the author analyzed 541 accident victims for one month before and after the amendment of The Road Traffic Law. The findings of study were summerized as follow: 1. Traffic accidents were decreased 36.2% after amendment of The Road Traffic Law than before, which were decreased highly in the low education group and the drive career over ten years group. 2. Traffic accidents were most frequent during the time 12:00-20:00. For the comparison between before and after amendment of The Road Traffic Law, during the time between 20:00-24:00, the traffic accident was decreased with 54.3%, but during the time between 24:00-04:00, the traffic accident was increased with 70%. 3. Traffic accidents by the motorcar was most frequent, but the rate by bus and microbus was highly decreased after the amendment of traffic law. For the cause of accidents, unobeyed safety driving was most frequent cause, but that was decreased conspicuously among alcohol drinking driving and over speed driving. 4. Most patients were injured mildly, and traffic accident rate of it was far lower than injured severely or death after the amendment of the traffic law. Most traffic accidents were sprain and contusion. Fractures were decreased the highest rate after the amendment of the Road Traffic Law. The most patients was treated for 2 weeks, but treated over 4 weeks was decreased least. 5. For the state of traffic accidents, severe injuries, head traumas and fractures were higher rate among drinking driving, but mild injuries, sprains and contusions were higher rate among nondrinking driving. The duration of treatment was short for the accidents by non-drinking drive, but that was long among by the drinking drive.

원위기저 비복동맥 피판술

이동걸,이동훈,이정형,조병채,백봉수 大韓成形外科學會 1999 Archives of Plastic Surgery Vol.26 No.3

Reconstruction of soft tissue defect with exposure of the tendons and bone in the lower third of the leg and the heel represents a challenge to plastic surgeons. The sural artery flap is a fasciocutaneous flap supplied by the sural artery that accompanies the sural nerve and connects with a septocutaneous perforator of the peroneal artery via a suprafascial network of vessels. For the coverage of soft tissue defects, we operated on 10 patients using a distally-based sural artery flap. The sites of the soft tissue defect were the lower third of the leg in 7 cases and the heel in 3 cases. The size of flap varied from 3.5x4cm to 12x18cm. Nine of 10 flaps survived completely. One flap in which the sural nerve was preserved showed partial necrosis but healed spontaneously. Two flaps showed slightly venous congestion which disappeared after a few days. The advantages of the sural flap are a reliable blood supply, easy and quick elevation of the flap, preservation of the major artery and minimal donor site morbidity. The disadvantage of the flap is hypoesthesia at the lateral part of the foot. In conclusion, the distally-based sural artery flap can be used safely for soft tissues coverage in the lower third of the leg and the heel.

ZVS를 이용한 SEPP 고주파 공진 인버터의 특성해석

김동희,노채균,김종해,민병재,배상준 嶺南大學校 工業技術硏究所 1997 工業技術硏究所論文集 Vol.25 No.1

Applied the high frequency switching technology to the ower conversion circuits, the turn on and off loss of switch point out practically large the point at issue, in order to reduce switching loss, the switching method using tank resonant circuit be connected serial and parallel with load have been continuously investigated. This paper was described about principle and form of proposed circuit made use of soft switching technology ZVS(Zero Voltage Switching) and ZCS(Zero Current Switching) to reduce turn on and off loss at switching. Also, the analysis of the proposed circuit is described generally by using normalized parameter and basic operating principle and driving characteristics have been evaluated as to switching frequency and load parameter. Based on the charactristics value, a method of circuit design is proposed. In addition, Pspice's simulation and experimental waveforms are compared with theoretical ones. The experimental results shows that the proposed Inverter can be used practically such as power source system for induction cooker etc.

흰쥐 경동맥 손상 모형에서 체외 방사선조사에 의한 신내막 과증식억제 : Intercellular Adhesion Molecule-1과 Vascular cell Adhesion Molecule-1의 역할 The Possible Role of Intercellular Adhesion Molecule-1 and Vascular Cell Adhesion Molecule-1

강동헌,승기배,장기육,임상현,정해억,임효영,김연실,채장성,김재형,홍순조,최규보 대한순환기학회 1999 Korean Circulation Journal Vol.29 No.9