Benzo(a)pyrene에 의해 유도된 간기능 장해에 미치는 당귀의 효과

윤수홍,조수열,이윤경,하두현 한국환경독성학회 1992 환경독성보건학회지 Vol.7 No.1

This study was performed to investigate the effect of Angelicae gigantis Radix extract on the hepatic detoxifying enzyme activities and lipids. Male sprague-dawley rats were administrated the extracts with benzo(a)pyrene, a hepatotoxic agent, inducing liver damages. Results obtained from this study were as follows: 1. The markedly increased enzyme activities (AST, ALT, LDH, ALP, γ-GTP, GSH -Px) in B(a)P induced groups tended to be decreased by the treatment of the Angelicae gigantis Radix extract. 2. Liver GSH content and lipid peroxide activity were decreased by the administration of the extracts. 3. It tended that the curative effects were better than the protective effects of the extracts.

레이저 스페클간섭법에 있어서 스페클크기와 측정 한계에 관한 연구

윤성운,김경석,양승필,정현철,김정호,이도윤 한국공작기계학회 1996 한국생산제조학회지 Vol.5 No.1

The high coherence of laser beam has made it possible to observe interference effects even in the light scattered from rough surfaces. That's why, when object with a scattering surface is illuminated with laser light, we do see a speckled appearance due to random interference. This sort of unique property of laser speckle has brought into existence the new noncontacting techniques such as speckle metrology method of measuring deformation, displacement, and vibration etc of objects with high optical sensitivity. The measurable range of speckle metrology especially used to measure in-plane information, however, is limited by some factors, the so-called strain, rotation, tilt of surface and out of displacement perpendicular to the plane of analysis. This restrictions severly limits the measurable range of speckle metrology by causing the decorrelation of speckle patterns. It is the purpose of this paper to give a survey on the measurable limitation of speckle photography method that is one of speckle metrology. Namely we will discuss the mutual relationships and problems of each limitations adding the restriction of the largest and smallest displacement measurable with speckle methods.

고지방 케톤 생성 식이를 먹인 백서 뇌에서 단백질 발현의 변화

정현정,윤도준 관동대학교 의과학연구소 2001 關東醫大學術誌 Vol.5 No.1

Ketogenic diet has been known to be effective on the treatment of epilepsy for a long period. Recently ketogenic diet therapy was revitalized because it was known to be a good treatment modality for the intractable childhood epilepsy. The clinical efficacy of the ketogenic diet has now been well-documented. Although a number of suggestions regarding underlying mechanism have been proposed, the mechanism of ketogenic diet on the epilepsy is still uncertain. To search the protein related to the mechanism of ketogenic diet therapy, in this study we have induced the ketosis in young rat by feeding high-fat ketogenic diet and analyzed the alteration of protein expression in the brain using SDS-PAGE and 2D electrophoresis technique. Some proteins were newly expressed in the rat brain fed on ketogenic diet, however, others were only found in the rat brain fed on normal diet. We conclude that ketogenic diet feeding makes changes of protein expression in rat brain, and these changes may be associated with the mechanism of ketogenic diet therapy.

Z_nF_2:M_n薄膜의 電場發光에 관한 硏究

李相潤,金道聖,朴相鉉 경북대학교 교육대학원 1980 논문집 Vol.12 No.-

Thin films of ZnF_2:Mn sandwiched by SiO semi-insulating layers were prepared using the thermal vacuum evaporator. These films showed both AC and DC electroluminescence (EL). The brightness B was measured as a function of applied voltage V. Then the characteristic hysteresis curve was observed in B-V relation. We could see the photoluminescence (PL) in the crystalline powder of ZnF_2: Mn, and the peak of emitting spectrum in EL was the same as in PL.

유도 '되치기 본'의 개선 방안에 관한 연구

김의환,김도준,김규수,김관현,김종달,최종삼,조용철,박순진,윤익선,안병근,정 훈,김미정,한성철 龍仁大學校 武道硏究所 1999 武道硏究所誌 Vol.10 No.1

The purpose of this study was to reform practically a Korean Judo's Doechigi-Bon(Forms of Counterattack, judo's Gaeshi no Kata, Judo's Uradori no Kata, Judo's Gonosen no Kata) that was established in 1955 Korea, according to changing of techniques by Judo's modernization, in order to have Judo's carefulness and systematic diffusion. Reform procedure of Judo's Doechigi-Bon was 1st stage, Questionnaire survey 303 judokas, 2nd stage, Technical seminar by judo experts(12 judo professor) 4 times, 3rd stage, wording report for reform, 4rd stage, Discussion and judgement of Teaching and Judgement commission of Korean judo Association(KJA), 5th stage, Public hearing for reform in KJA, 6th stage, Report and decision of board of directors in KJA, 7th stage, public publication of Judo News(No.53) in KJA. Basic principle of reform of Judo's Doechigi-Bon were as table 1. Table 1. Basic principle of reform of Judo's Doechigi-Bon ------------------------------------------------------------------------------- Items Reformed Key Points of Judo's Doechigi-Bon ------------------------------------------------------------------------------- 1. Structure 1) Grand classification : Classified by 3 parts(1,2,3Gyo) 2)Medium classification : Te waza, Goshi waza, Ashi waza devided per each part(Gyo) 3)Sub-classification : Classified five techniques per each part(Gyo) 2. Contents 1) Selected established techniques as possible 2) Considered rationalty and overlapping of counterattack techniques 3. Decision of Conterattack techniques 1) Refered to results of Basic Questionnaire survey 2) Priority to decisions of Judo expert technical seminar -------------------------------------------------------------------------------- Reformed Korean Judo's Doechigi-Bon(Forms of Counterattack techniques-KJA, 1999) are as follows: 1. Gyo; ① Uki otoshi -> Uchi mata ② Harai goshi -> Harai goshi gaeshi ③ O soto gari -> O soto gake ④ Ko uchi gari -> Sasae tsurikomi ashi ⑤ O uchi gari -> Ko soto gari 2. Gyo; ① Ippon seoi nage -> Okuri eri jime ② Tsuri domi goshi -> Uki waza ③ Okuri ashi harai -> Okuri ashi harai ④ Ko soto gari -> Tai otoshi ⑤ Hiza guruma -> Hiza guruma 3. Gyo; ① Kata guruma -> Sumi gaeshi ② Tai otoshi -> Ko soto gari ③ Hane goshi -> Harai tsurikomi ashi ④ Uchi mata -> Tai otoshi ⑤ Tomoe nage -> O uchi gari

하악전돌증의 악교정수술 후 연조직 형태변화에 대한 연구

성상진,박현도,김재승,문윤식 대한치과교정학회 2000 대한치과교정학회지 Vol.30 No.3

악교정수술에 관한 치료계획은 치료결과에 관한 정확한 예측을 바탕으로 수립되는 것이 바람직하며 이는 심미적인 결과를 얻기 위한 가장 중요한 요소 중에 하나이다. 성인에서 골격성 하악전돌증의 치료는 하악골후퇴술을 이용한 악교정수술법이 주로 이용되는데, 술후 턱끝의 돌출도가 과도하게 감소되어 하악전진이부성형술을 추가로 시행해야 하는 경우 하악골과 턱 부위의 연조직 변화방향이 상이하게 나타나므로 술후 연조직 변화를 정확히 예측하는데 한계가 있다. 본 연구에서는 골격성 하악전돌증을 주소로 악교정수술을 시행한 성인을 대상으로, 상행지시상분할골절단술(BSSRO)만을 시행한 경우(A군) 11명과 하악전진이부성형술(advancement genioplasty)도 같이 시행한 경우(B군) 9명의 경조직과 연조직 변화의 상관관계를 알아보기 위하여, 수술 8개월 이후에 채득된 측모두부계측방사선사진을 비교하여 다음과 같은 결과를 얻었다. 1. E-line에 대하여 상순은 더 돌출되고 하순은 더 후퇴되어 입술의 형태가 개선되었으며,하악전진이부성형술을 병행한 경우 하순의 돌출도는 더 개선되었다. 2. 두 군 모두에서 상순은 후방이동하고 비순각은 증가하였다. 3. 술후 B점에 대한 연조직 POGs점의 변화율은 A군에서 84%, B군에서 66%로 나타났으며 두 군간에 통계적 유의성이 있었다. 4. 경조직과 계측점의 수직변화량은 A군에서 감소하였다. The treatment plan for orthognathic surgery must be based on accurate predictions, and this can be produced the most esthetic results. Treatment of prognathic mandible in adult is usually orthognathic surgery using mandible set back, but mandible with retruded chin point is needed additional chin augmentation. In this case, the directions between mandible and chin point are different therefore, the prediction of soft tissue reactions must be modified. In this study, we materialize the patients who was taken orthognathic surgery due to prognathic mandible, 11each(Group A) was taken only Bilateral Sagittal Sprit Ramus Osteotomy (BSSRO), 9each(Group B) was taken additional advancement genioplasty. The lateral cephalometric radiography taken 8 months later after orthognathic surgery by this patients were used. The results of this study were as follows : 1.The profile of lips was favorable after surgery due to upper lip to E-line became prominent and lower lip to E-line was retruded. 2.In both group, upper lip moved posteriorly and nasolabial angle was increased. 3.The ratio of the soft tissue profile change in POGs point to skeletal B point movement was 84% in group A and 66% in group B, and there was statistical significance between group A and group B. 4.Vertical movement of hard tissue points is decreased in group A.

보조기를 이용한 족관절 외과 골절의 비수술적 치료

최남홍,곽호윤,송백용,배상욱,이인묵,김도현 대한골절학회 2003 대한골절학회지 Vol.16 No.3

목적: 이번 연구의 목적은 보조기를 이용하여 최소 전위된 족관절 외과 골절의 보존적 치료 결과를 알아보는 것이다. 대상 및 방법: 11명 (11예)의 환자들이 수상 후 8주간 전 체중 부하 보행으로 보존적 치료를 받았다. 적응증으로는 3㎜ 이하의 골절 전위, 내과 부분의 동통과 부종이 없거나 있어도 미약한 경우, 거골의 외측 전위가 없는 경우로 삼았다. 환자들은 AOFAS (the American Orthopedic Foor and Ankle Society) Ankle-Hindfoot Scale에 의해 평가받았다. 결과: 평균 103주 (36~192주)의 추시 관찰을 하였으며, 전례에서 발목 관절의 운동 범위는 정상이었다. 평균 AOFAS Ankle-Hindfoot Scale 점수는 95점이었다. 결론: 보조기를 이용한 보존적 치료의 장점은 조기에 전 체중 부하 보행을 하며 일상생활 및 사회생활을 영위할 수 있다는 것, 환자의 편안함, 그리고 재활 치료 기간의 단축이었다. 그러므로 최소 전위된 족관절 외과 골절에 보조기를 이용한 보존적 치료는 권할만하다. Purpose: The purpose of this study was to evaluate the outcome of conservative treatment for minimal displaced lateral mallolar fracture using ankle brace. Materials and Methods: Eleven patients (eleven ankles) underwent conservative treatment with ankle brace for 8 weeks with full weight bearing ambulation. Inclusion criteria were minimal displacement (<3㎜) of fracture, no or mild tenderness or swelling on medial malleolar area and no lateral shift of talus. The patients were evaluated with AOFAS (the American Orthopedic Foot and Ankle society) Ankle-Hindfoot scale. Result: Average follow up was 103 weeks (36~192). All cases had normal range of motion of ankle. The average score of AOFAS Ankle-Hindfoot scale was 95 points. Conclusion: The advantages of conservative treatment with ankle brace were early return to daily activity and work, comfort to the patients and a short period of rehabilitation. Conservative treatment with ankle brace for minimal displaced lateral malleolar fracture is recommended.

iTECH 바닥 슬래브의 시공단계별 진동특성에 관한 연구

이윤경,주영규,윤성원,김도현,김상대 대한건축학회 2005 大韓建築學會論文集 : 構造系 Vol.21 No.3

The story height of the tall buildings is the significant factor due to the limited construction area within the central city such as Seoul. Therefore we developed iTECH(Innovative Technical Economical & Convenient Hybrid) system to reduce story height. Since the top flange of the proposed beam is within the slab, the vibrational characteristics have to be verified by the test. The purpose of this paper is to study on vibration characteristics of floor with iTECH composite system and to evaluate the serviceability. In this research, natural frequency, damping ratio and peak acceleration were measured at experiments for each construction step such as steel erection stage, concrete casting stage and finishing stage. The test results are compared with that of the code. As a result, the proposed composite slab showed enough vibrational characteristics.

Concordance Analysis를 이용한 임도개설의 순위결정에 관한 연구

차두송,김종윤,정도현,지병윤 江原大學校 森林科學硏究所 1997 Journal of Forest Science Vol.13 No.-

이 논문은 Scoring법의 Concordance Analysis를 이용하여 전국 11개 지역을 대상으로 임도노선의 개설순위를 결정하였다. 그 결과 우위성 지수(Concordance Index)에 의한 임도개설 우선순위는 대상지역 9 > 5 > 11 > 10 > 6 > 1 > 3 = 4 > 2 > 7 > 8으로 나타났으며, 열세성지수(Dis-concordance Index)에 의한 임도개설 우선순위는 대상지역 9 > 3 > 4 > 5 > 10 > 8 > 1 > 11 > 6 > 7 > 2로 나타났다. By the means of concordance analysis among scoring methods, this study was to determine the priority order of forest road construction in 11 areas. The results have shown that the Priority order by concordance index was ranked by area 9, 5, 11, 10, 6, 1, 3=4, 2, 7 and 8, and that by dis-concordance index by area 9, 3, 4, 5, 10, 8, 1, 11, 6, 7 and 2.

인간 재조합 인터루긴-32 면역조절작용에 대한 유세포 분석

이광수,김영관,채정일,심정현,김은미,강형식,김수현,윤도영,명평근 충남대학교 생물공학연구소 2006 생물공학연구지 Vol.12 No.-

Xenotransplantation of porcine organs has the potential to overcome the severe shortage of human tissues and organ available for human transplantation. however, it remains various hurdles for clinical xenotransplantation. In pig and mouse xenotransplantation, porcine xenograft evoke a strong cellular rejection response in immunocompetent host and grafts are destroyed within a week. This cellular immune response could involved both T cells and NK cells. A number of groups have shown that human NK cells can recognize and damage porcine endothelial cells. In addition, human T cells can respond to porcine endothelial cells through both direct and indirect mechanisms. Cellular rejection of porcine tissues requires T cells, particularly CD4^(+) cells. A new cytokine recombinant human interleukin-32α,β(IL-32α,β) has a role innate and acquired immune system. In order to investigate the role of recombinant mouse IL-18 and recombinant human IL-32α,β in xenograft rejection, we transplanted the PK(15) cells to C57BL/6 mice with or without intraperitoneal injection of recombinant mouse IL-18 or recombinant human IL-32 α,β. It was analyzed the population of NK cell, T cell and B cell in the C57BL/6 mice transplanted with PK(15) cells and recombinant mouse IL-18 or recombinant human IL-32α,β by flow cytometry analysis. As a result, lymph node and thymus of PK15/IL18, PK15/IL32α and PK15/IL32β injected group were increased to T cell activation population than normal injected groups. CD8^(+) T cells were decreased in lymph node of PK15/IL18, PK15/IL32α and PK15/IL32β injected groups. CD4^(+) T cells were increased in lymph node cell of PK15/IL32α and PK15/IL32β injected group and also, B cell population were increased in lymph node cell and spleen of PK15/IL18, PK15/IL32α and PK15/IL32β injected group. Therefore, we suggest that recombinant mouse IL-18 and recombinant human IL-32α,β suppress xenograft rejection in cellular xenotransplantation.