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항생제 다제내성균 Staphylococcus aureus SA2로부터 분리한 테트라사이클린 내성 플라스미드 pKH6의 염기서열
이대운,윤성준,김우구,신철교,임성환,이백락,문경호 한국미생물생명공학회 ( 구 한국산업미생물학회 ) 1996 한국미생물·생명공학회지 Vol.24 No.4
한국에서 임산균주로부터 분리한 테트라사이클린(Tc) 내성 플라스미드 pKH6의 전체 염기서열을 결정하여 가장 대표적인 Tc 내성 플라스미드인 pT181과 비교하였다. pKH6의 전체 길이는 4439bp로 pT181과 동일하게 나타났으며 염기서열은 7개의 염기에서 차이를 보였다. 전부 다 염기쌍이 치환된 형태로 나타났으며 그 중 3개는 coding 부위에서 일어났다. coding 부위에서 일어난 경우에도 1개는 동일한 아미노산을 coding 하였기 때문에 pT181과 차이가 없었으며 RepC와 Pre 단백질에 있어 각각 1개의 아미노산에서 차이를 나타내었다. The complete nucleotide sequence of pKH6, a tetracycline-resistance (Tc^r) plasmid isolated from multi-drug resistant Staphlococcus aureus SA2, has been determined and compared with that of the staphylococcal Tc^r plasmid pT181. The nucleotide sequences of the two plasmids are in agreement except for 7 nucleotides. All differences are caused by base pair substitutions. Among 6 substitutions, 3 occurred in coding regions. However, only tow base substitutions in coding regions resulted in changes of amino acid sequences in two different ORFs of repC and Pre proteins.
피칸(Carya illinoensis C. KocH)으로부터 지질대사물질의 분리 및 동정
송명종,한민우,양혜정,이대영,노영덕,백남인 경희대학교식량자원개발연구소 2007 硏究論文集 Vol.26 No.1
피칸(Carya illinoensis C. Koch) 열매를 80% MeOH로 추출하고, 추출물을 극성에 따라 n-hexane, CHCl_(3), EtOAc, n-BuOH 및 물로 분배, 추출하였다. 이 중 EtOAc분획으로부터 silica gel column chromatography를 반복하여 4종의 지질화합물을 분리하였다. 분리된 화합물 화학구조는, NMR 및 MS 등의 스펙트럼을 해석하여 oleic acid methyl ester, linoleic acid methyl ester, β-sitosterol, daucosterol(3-O-β-D-glucopyaranosyl β-sitosterol)으로 동정하였다. Carya illinoensis C. Koch was extracted with 80% aqueous MeOH, and the concentrated extract was partitioned with n-hexane, CHCl_(3), EtOAc, n-BuOH and H_(2)O, successively. From the EtOAc fraction, four compounds were isolated through the repeated silica gel column chromatographies. From the results of physico-chemical data including NMR, MS and IR, the chemical structures of the compounds were determined as oleic aicd methyl ester(1), linoleic aicd methyl ester(2), β-sitosterol(3), and daucosterol(4). They were the first to be isolated from C. illinoensis.
박길문,이행남,백대우,손현철 朝鮮大學校 機械技術硏究所 2000 機械技術硏究 Vol.3 No.1
In this study, Flow characteristics of turbulent unsteady flows in a square-sectional 180°curved duct were experimentally investigated. Experimental studies for air flow were conducted to measure pressure distributions in the square-sectional 180°curved duct by using a magnehelic differential pressure gage. The experiment were conducted in nineteen sections from the inlet (ø=0°) to the outlet(ø=180°) of the duct at 10°intervals. The results obtained from the experimentation are summarized as follows. (1) In the turbulent oscillatory flow, the pressure distribution was the largest in the accelerating and decelerating region of the bend angle of 90°and the pressure difference of the inner and outer walls was the largest before and after the bend angle of 90°. (2) In the turbulent pulsating flow, the pressure difference was the largest near the region of bend angle of 90°in the case of the middle region, and since then the pressure difference of the inner and outer walls became smaller.
Development of a scheduling algorithm and GUI for autonomous satellite missions
Baek, Seung-woo,Han, Sun-mi,Cho, Kyeum-rae,Lee, Dae-woo,Yang, Jang-sik,Bainum, Peter M.,Kim, Hae-dong Elsevier 2011 Acta astronautica Vol.68 No.7
<P><B>Abstract</B></P> <P>In this paper, a scheduling optimization algorithm is developed and verified for autonomous satellite mission operations. As satellite control and operational techniques continue to develop, satellite missions become more complicated and the overall quantity of tasks within the missions also increases. These changes require more specific consideration and a huge amount of computational resources, for scheduling the satellite missions. In addition, there is a certain level of repetition in satellite mission scheduling activities, and hence it is highly recommended that the operation manager carefully considers and builds some appropriate strategy for performing the operations autonomously. A good strategy to adopt is to develop scheduling optimization algorithms, because it is difficult for humans to consider the many mission parameters and constraints simultaneously. In this paper, a new genetic algorithm is applied to simulations of an actual satellite mission scheduling problem, and an appropriate GUI design is considered for an autonomous satellite mission operation. It is expected that the scheduling optimization algorithm and the GUI can improve the overall efficiency in practical satellite mission operations.</P>
Seung-Woo Son,Jung Ho Park,Ji-Min Baek,Do-Kwyn Kim,Seung Ryul Lee,Sang-Moon Lee,Jieon Yoon,Jungtaek Kim,Woo-Bin Song,Sunjung Kim,Dong Suk Shin,Yihwan Kim,Seung Heon Shin,Tae-Woo Kim,Jung-Hee Lee,Dae-H IEEE 2017 IEEE electron device letters Vol.38 No.6
<P>In this letter, we have investigated the properties of In0.53Ga0.47As quantum-well (QW) metal-oxide-semiconductor field-effect-transistors (MOSFETs) on a 300-mm(100) Si wafer. We have explored the impact of scaling down In0.53Ga0.47As channel thickness (t(ch)) from 15 to 5 nm. The fabricated devices show excellent electrostatic integrity, such as subthreshold-swing (SS) < 80 mV/decade and drain-induced barrier-lower (DIBL) < 20 mV/V. Furthermore, we have extracted the effective mobility (mu(n_eff)) of the fabricated devices to investigate the carrier transport properties of the InGaAs MOSFETs with different values of t(ch). The device with t(ch) = 15 nm displayed a value of mu(n_eff) = 2, 190 cm(2)/V-s at room temperature. This value was found to decrease as tch was scaled down.</P>
Jeon, Dae-Woo,Jang, Lee-Woon,Cho, Han-Su,Kwon, Kyeong-Seob,Dong, Myeong-Ji,Polyakov, A Y,Ju, Jin-Woo,Chung, Tae-Hoon,Baek, Jong Hyeob,Lee, In-Hwan Optical Society of America 2014 Optics express Vol.22 No.18
<P>We demonstrated the InGaN/GaN-based light-emitting diodes (LEDs) with SiO2 nanoparticles embedded in nanopillar GaN template. With the SiO2 nanoparticles placed between the GaN nanopillars, subsequent overgrowth of GaN layer started only on the exposed tips of the nanopillars and rapidly switched to the lateral growth mode. This resulted in a high quality GaN layer 'sitting' on the nanopillars and the layer of pores formed over the SiO2 nanoparticles. For multi-quantum-well LEDs grown on top of such template, ~3 fold increase in optical output was observed compared to reference samples. The effect is attributed mainly to the improved light extraction efficiency due to additional scattering in the nanopillars-SiO2-pores portion of the structure, also to the increased internal quantum efficiency caused by a decreased dislocation density and relaxed strain due to the GaN nanopillars.</P>
효율적인 위성 임무 스케줄링 운영을 위한 스케줄링 최적화 알고리즘 비교 연구
백승우(Seung-Woo Baek),조겸래(Kyeum-Rae Cho),이대우(Dae-Woo Lee),김해동(Hae-Dong Kim) 한국항공우주학회 2010 韓國航空宇宙學會誌 Vol.38 No.1
본 논문에서는 위성 임무 스케줄링을 효율적으로 수행하기 위한 스케줄링 최적화 알고리즘을 타부탐색 알고리즘과 유전 알고리즘을 이용해 디자인하고, 시뮬레이션을 수행한 비교 결과를 기술하였다. 위성 임무 스케줄링은 위성에게 요구된 작업들과 그에 따른 제한사항 및 다양한 변수들을 종합적으로 고려하여 상호간의 시간, 조건 등의 충돌을 회피함과 동시에 위성의 자원을 최대한 활용하여 운용할 수 있는 최적의 작업시간표를 생성하는 것이다. 위성 임무 스케줄링은 동시에 많은 변수를 고려해야 하기 때문에 연산양이 많고, 매 스케줄링 시 마다 동일한 과정을 반복적으로 수행해야 하므로, 스케줄링 최적화 알고리즘과 같은 위성 운영 자동화, 자율화가 요구되는 분야이다. 다양하게 이용되고 있는 두 가지 스케줄링 기법을 위성 임무 스케줄링 최적화에 적용해 보았다. A comparison of two kinds of scheduling optimization algorithms is presented in this paper. As satellite control and operation techniques have been developed, satellite missions became more complicated and overall quantity of missions also increased. These changes require more specific consideration and a huge amount of computation for the satellite mission scheduling. Therefore, it is a good strategy to make a scheduling optimization algorithm for the efficient satellite mission scheduling operation. In this paper, two kinds of scheduling optimization algorithms are designed with tabu-search algorithm and genetic algorithm respectively. These algorithms are applied for the same mission scenario and the results of each algorithm are compared and analyzed.
Woo Cheol Shin,Dahye Yoon,Seon Min Oh,Bo-Ram Choi,Yunji Lee,Hyoung-Geun Kim,Nam-In Baek,Geum-Soog Kim,Min-Ho Lee,Dae Young Lee 한국식품영양과학회 2021 한국식품영양과학회 학술대회발표집 Vol.2021 No.10
Panax ginseng C. A. Meyer is distributed and cultivated in Korea, China, and Japan. Although their genetic information is the same, metabolites are different depending on the environmental factors of the cultivation region, and these metabolite changes cause differences in pharmacological effects. Metabolomics refers to the study of comprehensive metabolic changes occurring in the body. These metabolites may vary depending on disease, organic mutations, or environmental factors. For this reason, metabolites can be used for biomarkers. NMR and UPLC-Q-TOF/MS are the most widely used instruments for metabolite analysis. Recently, in metabolic studies, multi-platform metabolic studies using a combination of various instruments have been actively conducted, and this method can further help interpret metabolic analysis results. In this study, in order to determine the origin of ginseng and analyze biomarkers, metabolites of P. ginseng grown in Korea, China, and Japan were analyzed through multi-platform metabolomics using NMR and UPLC-Q-TOF/MS. The origins of P. ginseng were discriminated using multivariate statistical analysis and the candidate of biomarkers were identified.