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      • KCI등재

        한국와인평가가 지각된 가치 및 만족도에 미치는 영향

        강지원(Kang Gi-won),김대진(Kim Dae-jin),안신희(Ahn Shin-hee),고재윤(Ko Jae-youn) 한국호텔관광학회 2016 호텔관광연구 Vol.18 No.2

        As domestic spending on wine increases, the importance of the marketing strategies for wine products has been emphasized in the hospitality industry for the purpose of increasing business profits. Korean wine festivals is held in Young-dong and Youngcheon every October and November. Also, ‘Asian wine trophy’ is held every August in Dae-Jeon city of Korea. At that competition, several Korean wines won gold medals among the world’s wines. It means that the quality of Korean wine is being improved rather than before. And it can lead interest of Korea and Korean wine and enhanced status of Korea in the global wine market. The purpose of this study is to find out the relationship between Korean wine evaluation and perceived value and furthermore, relationship with satisfaction. In this study, a survey was carried out on experienced wine consumers over the age of 20 from October 15 through November 4, 2015. Overall, 315 questionnaires from internal customers were used for the final data analysis. The SPSS/PC version 20.0 and AMOS 20.0 statistics package programs were used for the confirmatory factor analysis, reliability analysis and pass analysis to test the hypotheses for this study. The result of the present study indicates that Korean wine evaluation was significant on Perceived value and the effect of Perceived value had a significant positive effect on satisfaction. The results of this paper suggests specific marketing strategy for winery owner of Korea and Korean wine company.

      • KCI등재

        고랭지 밭 유역의 융설에 의한 수질특성

        최용훈 ( Yong Hun Choi ),원철희 ( Chul Hee Won ),박운지 ( Woon Ji Park ),신민환 ( Min Hwan Shin ),신재영 ( Jea Young Shin ),이수인 ( Su In Lee ),최중대 ( Joong Dae Choi ) 한국물환경학회 ( 구 한국수질보전학회 ) 2012 한국물환경학회지 Vol.28 No.3

        In this study, Song-Cheon river Basin located at Dae-kwan-lyong Meyn in Kang-Won Province was monitored to analyze characteristics of non-point source pollution during the snowmelt period. The characteristics of NPS pollution such as runoff, change in water quality and pollutant loads by snowmelt were investigated from 23th February 2010 to 27th April 2010. The results showed that The climate change effects flow, turbidity and concentration of SS and COD with showing similar trend of fluctuation. Daily pollutant loads per unit area were SS 74.43 kg/ha/day, COD 1.25 kg/ha/day, BOD 0.21 kg/ha/day, TN 0.717 kg/ha/day, TP 0.141 kg/ha/day and the flow weight mean concentration has been SS 985.97 mg/L, COD 16.28 mg/L, BOD 2.67 mg/L, TN 9.302 mg/L, TP 1.834 mg/L, respectively. The flow and pollutant loads both of SS and of COD significantly increased during the snowmelt period. Because structurally loosen soil by freezing and thawing deteriorates water quality, research and management measures will be needed.

      • KCI등재후보
      • 수열합성법에 의한 제조된 MCM-41에 담지된 4급암모늄염 촉매를 이용한 페녹시메틸에틸렌 카보네이트의 합성

        신동환,유병수,이화수,박대원 한국공업화학회 2003 응용화학 Vol.7 No.1

        In the present study, the synthesis of phenoxy methyl ethylene carbonate (PMEC) from carbon dioxide and phenyl glycidyl ether(PGE) was investingated using mesoporous chloropropyl-methyl-MCM-41-supported quaternary ammonium salt catalysts. The influence of the amounl of modifier and quaternary ammonium salt structure on the conversion of PGE was discussed. The MCM-41-immobilized quaternary ammonium salts showed good catalytic activity even at the atmospheric pressure of carbon dioxide, and it could be reused with easy seperation.

      • KCI등재후보

        대뇌 기저핵 신경세포 일차배양에서 망간에 의해 유도된 Appoptosis : 형태학적인 소견

        신동훈,김상표,정용욱,배재훈,송대규,백원기 大韓産業醫學會 2000 대한직업환경의학회지 Vol.12 No.1

        목적 : 본 실험은 대뇌기저핵의 신경세포를 배양하여 망간(MnCl₂)을 투여한 후 망간독성에 의한 신경세포의 apoptosis를 형태학적인 소견으로 관찰하였다. 방법 : 배양된 신경세포에 0.01에서 10μM Mnc12를 48시간동안 처리한 후 TUNEL (TdT-mediated dUTP Nick End Labelling)법 및 투과전자현미경학적으로 관찰하였다. 결과 : TUNEL방법을 이용하여 관찰한 결과 TUNEL반응에 갈색으로 양성반응을 나타내는apoptotic 세포의 수가 대조군에 비해 MnCl₂를 투여한 군에서 유의하게 높게 나타났으며(P〈0.05), 투과전자현미경학적 소견상 대조군의 신경세포들은 핵인(nucleolus)이 두드러지게 특징적으로 보이면서 핵막과 세포질내 소기관들이 잘 보존되어 있으며, 세포질내망(ER)과 사립체(mitochondria)를 특히 많이 가지고 있었다. Mnc12를 48시간 동안 처리한 군에서 이질염색질(heterochromatin)이 핵막으로 이동하면서 응집되어 있었으며, 핵내 불규칙한 형태의 염색질이 나타나 분절이 진행되는 소견을 보였고, Apoptosis의 가장 특징적인 초기 소견인 막으로 둘러싸인 반달모양의 핵내염색질의 분절편(fragment-ed chromatin)과 주위의 상대적으로 정상적인 소기관으로 구성된 apoptotic body를 관찰할 수 있었다. 결론 : 신경세포에서 망간에 의해 apoptosis가 유도됨을 형태학적인 방법으로 확인할 수 있었으며 망간에 의한 세포사망양상에 apoptosis가 하나의 기전이 될 수 있을 것이다. Objectives : Manganese is cytotoxic to the central nervous system including basal gan-glia. Its toxic mechanism is related to oxidative stress, mediated by toxic free radicals but is specultives. In the present study , we have investigated to manifest apoptosis in man-ganese-induced cytotoxicity in primary neuronal cell culture of rat basal ganglia. Methods : To detect apoptotic neuronal cells were stained by the terminal deoxynu-cleotide (TdT) -mediated dUTP nick end-labelling (TUNEL) method and apoptotic changesin nuclei of neurons were observed by electron microscopy. Results : We showed that TUNEL immunostain showed brownish signal in the nuclei of apoptotic cells and the proportions of apoptotic cells in Manganese treatment groups were more higher than controls. On transmission electron microscopy, there were chromatine condensation with margination toward nuclear membrane and condensation of cyto-plasm in the treated with luM MnCl²for 48 hours in a basal ganglia neurons. Apoptotic bodies were found and consisted of semilunar-like condensed nuclei with relatively intact cytoplasmic organelles. Conclusions : Apoptosis appears to be one mechanism in the manganese-induced net-ronal cell death. Manganese intoxication is a convenient model for apoptosis study.

      • KCI등재
      • 외상성 주관절 구축의 수술적 치료

        신현대,이원석 충남대학교 의과대학 지역사회의학연구소 1996 충남의대잡지 Vol.23 No.2

        The eleven consecutive patients who had contracture of the elbow joint were treated by anterior capsulectomy and distraction arthroplasty without fascial interposition or anterior capsulectomy only. The ten elbows were post-traumatic contracture, and the one elbow was the ankylosis due to prolonged immoobilization after rain injury. Five patients were treated with distraction arthroplasty by modified Mayo Clinic Device and six patients underwent anterior capsulectomy under general or regional anesthesia. The mean preoperative arc of the total motion was 52 degrees(from 44 to 92 degrees of flexion). At follow-up examination, twelve to forty months postoperatively, of eleven patients, the mean arc of the total motion was 108 degrees (from 14 to 122 degrees of flexion). There were seven complications in seven of the eleven patients. Of these, the two were heterotopic ossification recurred in the posterior capsule of the elbow joint, so subsequently the ulnohumeral arthroplasty was performed at postoperative 8 months and 30 months later. The transient ulnar nerve injuries were occurred in two patients. The injured nerve dysfunction was resolved spontaneously. Two patients occured superficial wound infection. The pin site infection was occurred in one patient. The infection was subsided by dressing and antibiotics. Nine of the eleven patients who were followed for average 19 months satisfied with the results of the procedure because of the improved activity in carrying out daily life. No patients showed aggravation of pain. The three severely unstable elbow was improved from 3 points to 1 point on stability points. It was concluded that results of distraction arthroplasty and anterior capsulectomy could be gratifying and the range of motion of elbow was improved Significantly. But the technique is demanding and the rate of complications such as ulnar paresthesia or pin site infection is high especially distraction arthroplasty.

      • 더블 팬터그래프형 매니퓰레이터의 설계 및 수평위치제어

        홍대선,신중호,정원지,김성철 國立 昌原大學校 産業技術硏究所 1998 産技硏論文集 Vol.12 No.-

        In this paper, a double pantograph type manipulator activated by two slider joints is proposed for a fuel handling machine in atomic power plants. The manipulator consists of two parallelogrammic structures considered as simplified 2-DOF linkage systems. The linkage motion is controlled in such a manner that the joint rates of two linkages are constant and the movement of end-effector is horizontal, because the constant joint rates have advantages for the stable movement of the system. In addition, the static deflection of the proposed mechanism was analyzed using a transfer-stiffness matrix method.

      • 허혈성 심질환에 있어서 아데노신 급속 정맥투여후 관동맥압의 변화에 관한 연구

        봉종대,오종용,배성한,신원용,김철현,이광희,최태명,현민수,김성구,권영주 순천향의학연구소 1998 Journal of Soonchunhyang Medical Science Vol.4 No.2

        Background: Adenosine interacts with A1 receptors present on the extracellular surface of cardiac cells, activating K+channels in a fashion. It produces coronary vasodilatation and AV nodal block. The half-time is one to six second and has ultra-short action. In ischemic heart disease, fractional flow reserve(FFR) can be achieved safely with intravenous adenosine infusions at a rate of 150㎍/kg/min which cause maximal coronary hyperemia. Purpose: We investigated the patients who have had ischemic heart disease(n=8). After adenosine intravenous administration(150㎍/kg/min), the effect cause maximal hyperemia of coronary artery. During peak maximal hyperemia, we reported clinical findings, coronary hemodynamics and electrocardiogram findings. Methods: After diagnostic coronary angiography and left ventriculography, catheter was advanced into the ostium of coronary artery. We investigated coronary hemodynamics such as systolic coronary artery pressure, diastolic coronary artery pressure, mean coronary artery pressure and heart rate. To assess the use of adenosine for determination of fractional flow reserve, hemodynamics and electrocardiogram were measured at basal state and during peak maximal hyperemia. Results: Symptoms developed 1.5-2 minute after adenosine intravenous administration and each symptom disappeared 2-2.5 minute after adenosine administration. Two patients represented asymptomatic appearance and six patients complained of flushing, chest pain, palpitation and headache. In eight patients with ischemic heart disease, 1.5 minute after venous administration of 150㎍/kg/min of adenosine, coronary artery pressure decreased and heart rate increased significantly. Conduction abnormalities after administration of 150㎍/kg/min of adenosine were transient 2nd degree AV block 2 cases(25%). Conclusions: Adenosine is a potent ultra short-acting vasodilator. Although coronary artery pressure decreased and heart rate increased and mild cardiovascular symptoms occurred after continuous infusion of 150㎍/kg/min of adenosine, it is useful as an agent for determination of fractional flow reserve.

      • Flavobacterium meningosepticum에 의한 균혈증 1예

        장성원,유진홍,진승원,김선우,김연식,박순민,이대훈,최민호,최주연,신완식,강문원,강지민 대한화학요법학회 1997 대한화학요법학회지 Vol.15 No.1

        1996년 6월 카톨릭대학교 부천성가병원에 뇌경색으로 입원했던 61세 남자 환자의 혈액에서 Flavobacterium meningosepticum을 분리하였다. 환자는 폐렴을 동반한 패혈증의 예로 ceftriaxone과 metronidazole을 투여하였으나 입원 48시간만에 사망하였다. Flabovacterium meningosepticum is a rae cause of nosocomial infection which shows multi-drug resistance. It mainly invades patients with impaired immunity. Recently, we experienced a case of F. meningosepticum bacteremia in a patient with chronic debilitated state owing to stroke. The clinical progress was so rapid that he died within 48 hours. Blood culture revealed F. meningosepticum which showed characteristic yellow colony in blood agar plate.

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