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An Efficient Multicast Routing Algorithm for Packet-Switched Networks
Chung, Sung-Jin,Hong, Sung-Pil,Park, Bum Hwan 한국경영과학회 1998 한국경영과학회 학술대회논문집 Vol.- No.2
This paper has a dual purpose. First, we consider a relaxation algorithm which seems to be particularly suitable for multicasting routing problems. We show that the algorithm has polynomial complexity. Second, to measure the quality of solutions in comparison to the optimal solutions over a wide range of network sizes for which the computation of the optimal costs is too excessive, we also propose a random graph generation scheme in which an asymptotic lower bound on the expected optimal cost can be computed as a function of network node size.
( Chung Hoon Kim ),( Yong Pil Cheon ),( Kyung Hee Lee ),( Su Kyoung Kwon ),( Sung Hoon Kim ),( Hee Dong Chae ),( Byung Moon Kang ),( Chung Hoon Kim ) 대한산부인과학회 2012 대한산부인과학회 학술대회 Vol.99 No.-
We performed this study to investigate whether GnRH antagonist could affect endometrial receptivity and the addition of GnRH agonist could reverse the impact of GnRH antagonist. In female mice, superovulation was induced by standard protocol using pregnant mare serum gonadotropin (PMSG) and hCG. Female mice were divided into three groups. Group 1 was served as control group. In group 2, GnRH antagonist was injected concomitantly with PMSG. In group 3, GnRH antagonist was injected concomitantly with PMSG and GnRH agonist was added at the time of hCG injection. After hCG injection, the mice were mixed with fertile stud male mice and the copulation plug was checked in the next morning (day 1). Pregnant mice were sacrificed 4 days after hCG injection and their uteri were collected. Total RNA was isolated from endometrial tissue. Reverse transcription and Real-time PCR was performed. The expression of estrogen receptor (ER)α, ERβ, progesterone receptor (PR)α, PRβ, COX2, GnRH receptor (GnRHR)-1, leukemia inhibitory factor (LIF) and HOXA10 mRNAs was analyzed by realtime RT-PCR. There were no significant differences in the relative amounts of PRα, PR β, COX2 and GnRHR-1 mRNAs among three groups. The relative amounts of ERβ and LIF mRNAs were significantly higher in group 1 (p<0.05, p<0.01). On the other hand, the expression of ERα and HOXA10 mRNAs were significantly lower in group 2 (p<0.05, p<0.005) GnRH antagonist can reduce the expression of ERα, ERβ, LIF and HOXA10 mRNAs in murine endometrium, but the addition of GnRH agonist can reverse the amounts of ERα and HOXA10 mRNAs.
Vaccination and Complementary and Alternative Medicine in Patients with Inflammatory Bowel Disease
( Sung Bae Kim ),( Soo Jung Park ),( Sook Hee Chung ),( Kyu Yeon Hahn ),( Do Chang Moon ),( Sung Pil Hong ),( Jae Hee Cheon ),( Tae Il Kim ),( Won Ho Kim ) 대한장연구학회 2014 Intestinal Research Vol.12 No.2
Background/Aims: Vaccinations in patients with inflammatory bowel disease (IBD) are recommended to prevent infectiousdiseases. However, there are few reports of vaccination in IBD patients in Korea. The frequency of complementary and alternativemedicine (CAM) use is high despite its uncertain effectiveness. This study aimed to identify the rates of vaccination anduse of CAM in patients with IBD. Methods: A total of 219 patients attended an education session for IBD patients held at SeveranceHospital on March 23, 2013. We conducted a survey on vaccination and CAM use in IBD patients; 120 patients completedthe questionnaire. Results: The influenza vaccination rate was 44.2% and pneumococcal vaccination rate was 4.2%. Thirtyone(66%) patients were aware of the importance of vaccination. The vaccination rate was higher in patients who were awareof the importance of vaccination compared with that in patients who were unaware of the importance of vaccination (70.1%vs. 41.7%, P =0.004). The rate of CAM use was 30.0%. The most commonly used CAMs were oral products: vitamins (33.3%),red ginseng (25.0%), and probiotics (19.4%). Conclusions: Awareness of the importance of vaccination and actual vaccinationrates were low in IBD patients. Despite insufficient evidence on the effectiveness of CAMs in IBD patients, many patients usedCAMs. We believe that repeated education and promotion of vaccination are important. Further large-scale studies to investigatethe efficacy and safety of CAMs are warranted in patients with IBD. (Intest Res 2014;12:124-130)
Roles of unphosphorylated ISGF3 in HCV infection and interferon responsiveness
Sung, Pil Soo,Cheon, HyeonJoo,Cho, Chung Hwan,Hong, Seon-Hui,Park, Do Youn,Seo, Hyung-Il,Park, Su-Hyung,Yoon, Seung Kew,Stark, George R.,Shin, Eui-Cheol Proceedings of the National Academy of Sciences 2015 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF Vol.112 No.33
Chung, Ki-Hyun,Yang, Won-Ho,Heo, Sung-Pil The Korean Society of Mechanical Engineers 2002 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.16 No.5
Finite element analysis for the stress intensity factor (SIF) at the skin/stiffener structure with inclined central crack repaired by composite stiffened panels is developed. A numerical investigation was conducted to characterize the fracture behavior and crack growth behavior at the inclined crack. In order to investigate the crack growth direction, maximum tangential stress (MTS) criterion are used. Also, this paper is to study the performance of the effective bonded composite patch repair of a plate containing an inclined central through-crack. The main objective of this research is the validation of the inclined crack patching design. In this paper, the reduction of stress intensity factors at the crack-tip and prediction of crack growth direction are determined to evaluate the effects of various non-dimensional design parameter including; composite patch thickness and stiffener distance. We report the results of finite element analysis on the stiffener locations and crack slant angles and discuss them in this paper. The research on cracked structure subjected to mixed mode loading is accomplished and concludes that more work using a different approaches is necessary. The authors hope the present study will aid those who are responsible for the repair of damaged aircraft structures and also provide general repair guidelines.
( Pil Soo Sung ),( Si Hyun Bae ),( Jeong Won Jang ),( Do Seon Song ),( Hee Yeon Kim ),( Sun Hong Yoo ),( Chung Hwa Park ),( Jung Hyun Kwon ),( Myeong Jun Song ),( Chan Ran You ),( Jong Young Choi ),( 대한간학회 2011 Clinical and Molecular Hepatology(대한간학회지) Vol.17 No.4
Background/Aims: Enhanced replication of hepatitis C virus (HCV) is well described in the setting of moderate to severe immunosuppression. The aims of this retrospective study were to determine the incidence of enhanced HCV replication in hepatocellular carcinoma (HCC) patients undergoing transarterial chemolipiodolization (TACL) and to identify the factors associated with enhanced replication of HCV. The clinical pattern of enhanced HCV replication was compared with hepatitis B virus (HBV) reactivation during TACL. Methods: This study enrolled 49 anti-HCV-seropositive patients who were diagnosed with HCC between January 2005 and December 2010 and who underwent TACL using epirubicin and/or cisplatin with consecutive HCV RNA copies checked. For comparison, 46 hepatitis B surface antigen1-positive patients with HCC who were treated with TACL were also enrolled. The frequency, associated factors, and clinical outcomes of enhanced HCV replication were analyzed and compared with those of HBV reactivation during TACL. Results: Enhanced replication of HCV occurred in 13 (26.5%) of the 49 anti-HCV-seropositive patients during TACL. Of these 13 patients, 4 developed hepatitis, but none of the subjects developed decompensation due to the hepatitis. No significant clinical factors for enhanced HCV replication during TACL were found. Compared with HBV reactivation, the frequency of hepatitis attributed to enhanced HCV replication was significantly lower than that for HBV reactivation (8.2% vs. 23.9%, P=0.036). Conclusions: TACL can enhance HCV replication; however, the likelihood of hepatitis and decompensation stemming from enhanced HCV replication was lower than that for HBV reactivation in patients undergoing TACL. (Korean J Hepatol 2011;17:299-306)