Perturbed Hard Sphere 모델을 이용한 순수물질의 열학적 성질 계산

조찬휘,최호석 永同大學校 1999 硏究論叢 Vol.5 No.1

단순 perturbed hard-sphere 상태방정식을 사용하여 순수 유체의 열역학적 성질을 계산하였다. 계산에서는 각각 2개 또는 4개의 매개변수를 갖고 있는 방정식들을 사용하였고, 실험으로 구한 자료들과 비교해본 결과 4개의 매개변수를 갖고있는 방정식이 2개의 매개변수를 갖고있는 방정식에 비하여 실험결과와 잘 일치함을 보여주고 있다. 이는 실제 유체의 ?와 ?가 온도의 함수이기 때문이다. 그러나, 어떤 온도 영역에서는 2개의 매개변수를 갖고있는 모델이 실험 결과와 상당히 잘 일치하고, 유체의 유용한 열역학적 성질들을 큰 오차없이 효과적으로 계산할 수 있도록 해주기 때문에 유체의 열역학적 성질들의 빠른 예측이 필요한 실제 화학공정에서 다양한 용매들의 열역학적 성질의 예측에 사용될 수 있음을 알았다. We have calculated thermodynamic properties of pure fluids of using a simple perturbed hard-sphere equation of state (the Carnahan-Starling-van der Waals equation, denoted CS-vdW). In this calculation, we have used both 2 parameter equation and 4 parameter equation. It has been observed that 4 parameter model has shown better agreement with experimental results than 2 parameter model. It is because ? and ? of real fluids mildly depends on temperature. Since, however, 2 parameter model also has shown considerably good agreement with experimental results within certain temperature range and has effectively calculated useful thermodynamic properties of fluids, it may have been used to estimate thermodynamic properties of various solvent molecules in real chemical processes.

디지털 시스템 설계를 위한 범용 하드웨어 보드개발

조윤석,김호찬 濟州大學校 情報通信硏究所 1998 情報通信硏究所論文集 Vol.1 No.-

This paper presents a dedicated general-purpose FPGA board on which a digital system is implemented without additional hardware efforts. The board provides several I/O interfaces which consist of LED block. 7-segment block, LCD block. memory block and input switch block. The maximum number of logic gate to be implemented on the board is 10,000 gates. Also. PC interface block and serial communication block which are used to communicate with external devices are incorporated onto the board. By implementing a Viterbi decoder for decoding a convolutional code with rate 1/2 and constraint length 3 on the board. we show that the board can be utilized in practical applications.

리스페달 정(리스페리돈 2㎎)에 대한 리스펜 정의 생물학적 동등성

조혜영,박은자,강현아,백승희,이석,박찬호,문재동,이용복 한국약제학회 2004 Journal of Pharmaceutical Investigation Vol.34 No.2

The purpose of the present study was to evaluate the bioequivalence of two risperidone tablets, Risperdal (Janssen Korea Co., Ltd) and Rispen (Myung In Pharm. Co., Ltd), according to the guidelines of Korea Food and Drug Administration (KFDA). The risperione release from the two risperidone formulations in vitro was tested using KP Ⅷ Apparatus Ⅱ method with various of dissolution media (pH 1.2, 4.0, 6.8 butter solution and water). Twenty four healthy male subjects, 23.33±2.10 years in age and 69.24±8.05 kg in body weight, were divided into two groups and a randomized 2×2 crossover study was employed. After one tablet containing 2 ㎎ as risperidone was orally administered, blood was taken at predetermined time intervals and the concentration of risperidone in serum were determined using HPLC method with UV detector. The dissolution profiles of two formulations were similar at all dissolution media. Besides, the pharmacokinetic parameters such as AUC_(t), C_(max) were calculated and ANOVA test was utilized for the statistical analysis of the parameters using logarithmically transformed AUC_(t), C_(max) and untransformed T_(max). The results showed that the differences between two formulations based on the Risperdal were 0.20, -1.29 and -11.09% for AUC_(t), C_(max) and T_(max), respectively. There were no sequence effects between two formulations in these parameters. The 90% confidence intervals using logarithmically transformed data were within the acceptance range of log(0.8) to log(1.25) (e.g., log(0.90)∼log(1.03) and log(0.84)∼log(1.09) for AUC_(t) and C_(max), respectively). Thus, the criteria of the KFDA guideline for the bioequivalence were satisfied, indicating Rispen tablet and Risperdal tablet were bioequivalent.

시클러 캡슐(세파클러 250㎎)에 대한 경보세파클러 캡슐의 생물학적동등성

조혜영,강현아,김세미,박찬호,오인준,임동구,문재동,이용복 한국약제학회 2005 Journal of Pharmaceutical Investigation Vol.35 No.1

The purpose of the present study was to evaluate the bioequivalence of two cefaclor capsules, Ceclor (Lilly Korea Co., Ltd.) and Kyongbocefaclor (Kyongbo Pharm. Co., Ltd.), according to the guidelines of the Korea Food and Drug Administration (KFDA). The release of cefaclor from the two cefaclor formulations in vitro was tested using KP VIII Apparatus II method with various dissolution media (pH 1.2. 4.0. 6.8 buffer solution and water). Twenty four healthy male subjects. 22.96±1.52 years in age and 67.03±7.90 kg in body weight, were divided into two groups and a randomized 2x2 cross-over study was employed. After one capsule containing 250 mg of cefaclor was orally administered, blood was taken at pre-determined time intervals and the concentrations of cefaclor in serum were determined using HPLC method with UV detector. The dissolution profiles of two formulations were similar at all dissolution media. In addition. the pharmacokinetic parameters such as AUC_(t), C_(max) and T _(max) were calculated and ANOVA test was utilized for the statistical analysis of the parameters using logarithmically transformed AUC_(t). C_(max) and untransformed Tmaa. The results showed that the differences between two formulations based on the reference drug, Ceclor. were -1.90%, 2.68% and -7.60% for AUCt, C_(max) and T_(max), respectively. There were no sequence effects between two formulations in these parameters. The 90% confidence intervals using logarithmically transformed data were within the acceptance range of log 0.8 to log 1.25 (e.g., log 0.91-log 1.06 and log 0.92-log 1.18 for AU', and C_(max), respectively). Thus. the criteria of the KFDA bioequivalence guideline were satisfied, indicating Kyongbocefaclor capsule was bioequivalent to Ceclor capsule.

비유피-4 정(염산프로피베린 20㎎)에 대한 건일염산프로피베린 정의 생물학적동등성

조혜영,박은자,강현아,백승희,김세미,박찬호,오인준,문재동,이용복 한국약제학회 2004 Journal of Pharmaceutical Investigation Vol.34 No.5

The purpose of the present study was to evaluate the bioequivalence of two propiverine hydrochloride tablets. BUP-4 (Jeil Pharm. Co., Ltd.) and Kuhnil Propiverine Hydrochloride (Kuhnil Pharm. Co., Ltd.), according to the guidelines of the Korea Food and Drug Administration (KFDA). The propiverine release from the two propiverine hydrochloride formulations in vitro was tested using KP Ⅷ Apparatus Ⅱ method with a variety of dissolution media (pH 1.2, 4.0, 6.8 buffer solutions, water and blend of polysorbate 80 into pH 6.8). Twenty six healthy male subjects, 23.73 ± 2.79 years in age and 67.04 ± 7.93 kg in body weight, were divided into two groups and a randomized 2 x 2 cross-over study was employed. After one tablet containing 20 mg as propiverine hydrochloride was orally administered, blood was taken at predetermined time intervals and the concentrations of propiverine in serum were determined using HPLC method with UV detector. The dis-solution profiles of two formulations were similar at all dissolution media. Besides, the pharmacokinetic parameters such as AUC" C _(max) and T _(max) were calculated and ANOVA test was utilized for the statistical analysis of the parameters using logarithmically transformed AUC, C_(max), and untransformed T_(max). The results showed that the differences between two formulations based on the BUP-4 were 0.17%, 7.98% and 4.55% for AUC,, C_(max), and respectively. There were no sequence effects between two formulations in these parameters. The 90% confidence intervals using logarithmically trans-formed data were within the acceptance range of log(0.8) to log(1.25) (e.g., log(0.88)-log(l .12) and log(0.90)-log(l.15) for AUC, and _(max), respectively). Thus, the criteria of the KFDA bioequivalence guideline were satisfied, indicating Kuhnil Propiverine Hydrochloride tablet was bioequivalent to BUP-4 tablet.

와전류검사에 의해 검출된 증기발생기 전열관의 균열 특성

조찬희,남민우,김영호,양승한,이희종 한국비파괴검사학회 2004 학술대회 논문집 Vol.- No.-

The flaws detected at the steam generator tube of the Nuclear Power Plant are the wear indications by anti-vibration bars and circumferential cracks at the top of the tubesheet. It is easy to detect and size wear indications. Also the wear indications are commonly found at the steam generator tubes. However, the steam generator tube which includes crack indication is plugged because it is very difficult to predict the growth rate and the sizing error is high. The motorized rotating pancake coil has been used for the detection of circumferential crack since it is not possible to detect using the conventional bobbin probe. This paper describes the characteristics for the circumferential crack at the steam generator tubes of the Korean Standard Nuclear Power Plants.

自然科 學習資料 運營의 實態調査 : Centering around the primary school in Choong Buk Province

文燦祜,趙璇衡 淸州敎育大學校 1975 論文集 Vol.11 No.-

The science teaching materials in primary schools are very important to stimulate the curiosity of the children, and to advance their science inquiring process, and especially to educate effectively the children who are in the stage of concrete operations. This thesis is an analysis of the research on the actual state of administration of the science teaching materials in primary schools in Choong Buk Province. According to the analysis, the administration of the science curriculum is found difficult, that is, only 32% of the required materials had been prepared a very poor ratio. In addition, the difference of the preparations between city and rural schools is very significant is, 39% in city and 25% in rural. Between the city and rural schools, the correlation coefficient of the order difference(Spearman's ρ) is 0.49%. (the order is determined according to the great ratio of each prepared material to required). Therefore, We can tell that there is no great difference of the order according to the territory. We know that the preparation of new science teaching materials for use in the classroom is at a lower rate than the preparation of other teaching materials, whereas, the preparation is going to large in its degree according to their use, year by year. It appeared that most schools do not consider not only the using frequencies of the teaching materials, but also the needed amount of materials in a class. When retraining coursework opens, We will instruct the primary schoolteachers in the importance of the science teaching materials and in the differentiation of their usage. Lastly, the school administration should be assisted financially for the least quantity of materials necessary, and studied further for the methods of effective use.

벼, 콩 및 채소류에 대한 Mn-54, Co-60, Zn-65, Cs-137의 토양-작물체간 전이계수

박찬걸,조용우,최용호,김국찬,이창우,이강석,이정호 대한방사선 방어학회 1991 방사선방어학회지 Vol.16 No.2

벼, 콩, 상치, 당근, 호박의 가식부위에 대하여 몇가지 토양에 있어서 토양-작물체간 Mn-54, Co-60, Zn-65, Cs-137의 전이계수를 포트 재배에 의한 방사성 추적자 흡수실험을 통하여 조사하였다. 핵종간 전이계수는 거의 모든 경우 Zn-65>Mn-54>Cs-137>Co-60의 순이었다. 콩이 벼보다 전반적으로 한 자리 정도 높은 값을 보였고 채소류의 경우에는 대체로 상치에서 가장 높고 호박에서 가장 낮은 값을 보였다. 강산성 토양에서는 약산성 토양에서보다 전이계수가 훨씬 높았다. 본 조사결과에 입각하여 한국인의 섭식경로 피폭선량 평가에 이용하기 위한 각 핵종의 전이계수치가 작물별로 제안되었다. Soil-to plant transfer coefficients of Mn-54, Co-60, Zn-65 and Cs-137 were estimated for the edible parts of the rice, soybean, lettuce, carrot, and squash grown in different soils by radiotracer uptake experiments using pot cultures. The transfer coefficients of radionuclides were n the order of Zn-65>Mn-54>Cs-137>Co-60 in most of the cases studied. The coefficients for soybean were roughly and order of magnitude higher than those for rice. Among vegetables, lettuce mostly showed the highest value and squash, the lowest. In the strongly acidic soils. From the data obtained, crop-specific transfer coefficients of the four nuclides were proposed for the use in Korean food-radiation dose assessment.

우리나라 논 관개용 지하수 수질 특성

김진호,조광래,임수정,이경자,경기천,엄미정,김희권,김찬용,이영한,이신찬,윤순강 한국환경농학회 2003 한국환경농학회지 Vol.22 No.4

This study was carried out to evaluate the status of the groundwater quality for paddy fields irrigation in Korea. Water samples were collected at 130 sites throughout the country. Samples were collected at three seasons-April, July and October-in 2000. According to our survey, the groundwater was found to be suitable for irrigation purpose. Average EC was shown 0.286 dS/m. Nitrate-nitrogen and Cl^(-) concentration was 5.6 ㎎/L, 32.95 ㎎/L which satisfied the Korean Standards for Irrigation Water. Nitrate-nitrogen concentration in each province was shown as following orders: Jeju (11.17 ㎎/L) > Chungnam (8.16 ㎎/L) > Gyeongbuk (6.64 ㎎/L) > Gyounggi (5.91 ㎎/L) > Chungnam (4.95 ㎎/L) > Gyeongnam (3.91 mgk) > Jeonbuk (3.50 ㎎/L) > Jeonnam (3.27 ㎎/L) > Gangwon (2.91 ㎎/L). The concentration by sampling seasons were October (6.62 ㎎/L) > July (5.88 mg&) > April (4.78㎎/L). As the soil of Jeju Province is usually derived from volcanic ash soils mainly used for upland drops, it may influence the nitrate-nitrogen concentration of groundwater. The amount of rainfall also influence the water quality. But the COD_(Cr), were shown April (3.17㎎/L) > July (2.91 ㎎/L) > October (2.40 ㎎/L), it is highly related in the basal dose of organic matter fertilizers. This study demonstrated that groundwater quality was suitable for irrigation, but continuous monitoring is recommended for agricultural policy and developing OECD agricultural environment indicators.

小兒 血行性 化膿性 脊椎骨髓炎 : 3例 報告

金贊榮,郭英信,趙宗大,李銀浩 대한소아과학회 1969 小兒科 Vol.12 No.12