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      • KCI등재

        CVM을 통한 하이서울페스티벌의 가치평가

        Cai Yu Jin,Bo Ma,So Eun Kim 강원대학교 경영연구소 2010 Asia-Pacific Journal of Business Vol.1 No.1

        본 연구는 축제의 가치를 최대지불의사액(WTP)을 통해 측정하고자 시도되었다. 연구대상이 된 하이서울페스티벌은 서울의 대표축제로 육성하고자 2003년부터 개최된 축제이다. 서울시는 이를 통해 관광객을 유치하고 문화관광지로서 서울의 이미지를 재정립하여 경제적 이익을 창출하고자 하는데 목표를 두었다. 하지만 해마다 상이한 콘셉트와 행사 개최장소의 변경으로 인해 축제의 정체성이 모호하며, 초기의 목표와는 달리 가시적인 성과를 얻고 있지 못한 실정이다. 이러한 문제점에 착안하여 축제개최장소별 CVM을 활용한 가치추정을 통해 하이서울페스티벌의 가치를 추정하고, 향후 정책적 시사점을 도출하고자 본 연구를 수행하였다. 연구결과 축제개최장소별 비이용가치는 상이한 것으로 나타났는데 이는 각 장소별 프로그램의 성격과 개최장소의 특징에 기인한 것으로 추측된다. 또한 하이서울페스티벌의 비이용가치 추정을 통한 경제적 가치는 422억 원으로 나타나 현재 시민들이 느끼는 편익의 가치는 큰 것으로 나타났다. 즉 향후 하이서울페스티벌의 기획에 있어서는 장소성을 가진 장소에서의 특성화된 프로그램의 개발을 통해 방문객들의 만족도를 향상시켜 축제의 가치를 높이는 방안이 검토되어야 할 것이다. This article estimates the total evaluation of the festival and investigates the determinants of visitors' WTP(willingness to pay) for the festival. Hi Seoul Festival is a way to introduce Korean culture to other foreigners as well as to serve as an economic and cultural stimulus for Seoul. A contingent evaluation survey was conducted and a total of 763 useful samples were collected. The results show that the evaluation of the festival were different across three different WTPs which were calculated as 2,846 won, 3,321 won, and 4,838 won. The annual total benefits value is calculated as 433.767 billion Korean won. And visitors' sex and visitors' satisfaction(keep up festival, need to modify) was a important determinants of the WTP for a visit. These findings may provide guidance managers and practitioners who help maintain the Hi festival.

      • KCI등재

        관광과 삶의 질의 관계

        김채옥(Cai Yu Jin),송운강(Woon Gang Song) 한국관광연구학회 2006 관광연구저널 Vol.20 No.2

        The purpose of this paper is to research the relationship between tourism satisfaction and the quality of life(well-being) of non-institutionalized tourists. In results, tourism experiences of non-institutionalized tourists show a significant effect on tourism satisfaction, and tourism satisfaction also has a positive effect on subject well-being(SQOL) and psychological well-being(PQOL). Tourism experiences, however, do not directly influence on subject well-being and psychological well-being. Furthermore, Psychological well-being has a significant effect on subject well-being.

      • SCISCIESCOPUS

        Pantropical climate interactions

        Cai, Wenju,Wu, Lixin,Lengaigne, Matthieu,Li, Tim,McGregor, Shayne,Kug, Jong-Seong,Yu, Jin-Yi,Stuecker, Malte F.,Santoso, Agus,Li, Xichen,Ham, Yoo-Geun,Chikamoto, Yoshimitsu,Ng, Benjamin,McPhaden, Mich American Association for the Advancement of Scienc 2019 Science Vol.363 No.6430

        <P><B>Tropical interconnections</B></P><P>The El Niño–Southern Oscillation, which originates in the tropical Pacific, affects the rest of the world's tropics by perturbing global atmospheric circulation. Less appreciated than this influence is how the tropical Atlantic and Indian Oceans affect the Pacific. Cai <I>et al.</I> review what we know about these pantropical interactions, discuss possible ways of improving predictions of current climate variability, and consider how projecting future climate under different anthropogenic forcing scenarios may be improved. They argue that making progress in this field will require sustained global climate observations, climate model improvements, and theoretical advances.</P><P><I>Science</I>, this issue p. eaav4236</P><P>The El Niño–Southern Oscillation (ENSO), which originates in the Pacific, is the strongest and most well-known mode of tropical climate variability. Its reach is global, and it can force climate variations of the tropical Atlantic and Indian Oceans by perturbing the global atmospheric circulation. Less appreciated is how the tropical Atlantic and Indian Oceans affect the Pacific. Especially noteworthy is the multidecadal Atlantic warming that began in the late 1990s, because recent research suggests that it has influenced Indo-Pacific climate, the character of the ENSO cycle, and the hiatus in global surface warming. Discovery of these pantropical interactions provides a pathway forward for improving predictions of climate variability in the current climate and for refining projections of future climate under different anthropogenic forcing scenarios.</P>

      • KCI등재

        Triaxial Test Research on Mechanical Properties and Permeability of Sandstone with a Single Joint Filled with Gypsum

        Jin Yu,Xu Chen,Yan-yan Cai,Hongliang Liu 대한토목학회 2016 KSCE Journal of Civil Engineering Vol.20 No.6

        In this study, the mechanical properties and permeability variation in single joint rock samples filled with a gypsum layer were investigated. In order to simulate the inclined infilled joint, the solid cylinders were saw-cut at the dip angles of 90°, 60°, 45°, 30° or 0° with respect to the samples’ axes, and then joined together with gypsum. Triaxial compression experiments with permeability measurements were then performed using these prepared samples. The results indicated that the peak strength and failure modes change with the inclined angles. In comparison with the theoretical analysis of rock with a clean joint, infilling has a marked influence on the mechanical properties to some extent. In regards to the initial permeability, the results showed decreases of approximately two orders of magnitude with the increasing of the prefabricated joint angle, and the initial permeability of the samples with a prefabricated joint were all larger than the intact sample. The evolutionary trends of the permeabilities in triaxial compression in the sandstone samples were shown to be varied with a joint filled with gypsum at different angles, due to the fact that the changes of the inner structure are quite different during the loading process.

      • Alternative Messenger RNA Splicing of Autophagic Gene Beclin 1 in Human B-cell Acute Lymphoblastic Leukemia Cells

        Niu, Yu-Na,Liu, Qing-Qing,Zhang, Su-Ping,Yuan, Na,Cao, Yan,Cai, Jin-Yang,Lin, Wei-Wei,Xu, Fei,Wang, Zhi-Jian,Chen, Bo,Wang, Jian-Rong Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.5

        Beclin 1 is a key factor for initiation and regulation of autophagy, which is a cellular catabolic process involved in tumorigenesis. To investigate the role of alternative splicing of Beclin1 in the regulation of autophagy in leukemia cells, Beclin1 mRNA from 6 different types of cell lines and peripheral blood mononuclear cells from 2 healthy volunteers was reversely transcribed, subcloned, and screened for alternative splicing. New transcript variants were analyzed by DNA sequencing. A transcript variant of Beclin 1 gene carrying a deletion of exon 11, which encoded a C-terminal truncation of Beclin 1 isoform, was found. The alternative isoform was assessed by bioinformatics, immunoblotting and subcellular localization. The results showed that this variable transcript is generated by alternative 3' splicing, and its translational product displayed a reduced activity in induction of autophagy by starvation, indicating that the spliced isoform might function as a dominant negative modulator of autophagy. Our findings suggest that the alternative splicing of Beclin 1 might play important roles in leukemogenesis regulated by autophagy.

      • KCI등재

        ‘-子’계열 한자어에서 기원한 만주어 ‘-se’계열 단어에 대한 연구 - HMB(『御製淸文鑑』)에 등재된 어휘를 중심으로 -

        여채려 ( Yu¸ Cai-li·kim ),김양진 ( Ryang-jin ) 경희대학교 인문학연구원 2020 인문학연구 Vol.0 No.45

        본고는 ‘-se’ 로 끝나는 만주어 가운데 ‘X子’ 계열 한자어에서 기원 한 단어를 찾아 정리해 보고 그 단어의 제 양상 및 특징을 살펴보고 자 하였다. 이를 위하여, 먼저 만주어를 만주어로 풀이한 만주어 사전 HMB(1708, 『御製淸文鑑』)로부터 ‘-se’로 끝나는 만주어 ‘Xse’ 중 ‘X子’ 계열 한자어와 대응 관계가 있을 만 한 단어를 검색하여 1차 목록을 만들었다. 이렇게 추출한 1차 목록을 대상으로 하여, 『御製增訂淸文鑑』(1771)에 실린 만주어의 대역 한자 표제어나 여타의 만한합벽(滿漢合壁)의 문헌들로부터 이들 단어와 관련이 있을 한자어를 찾아 유형별로 비교 검토함으로써 이 만주어 단어들 속에 포함된 ‘-se’가 한자 접미사 ‘-子’와 관련되어 있을 개연성을 타진 하였다. 그 결과, 만주어 ‘-se’는 적지 않은 정도로 ‘-子’의 문법적인 의미와 대응됨을 확 인할 수 있었다. 본래 한자어 ‘-子’계열 단어에서 기원한 ‘-se’계열 한자어들은 어휘복제 (lexical replication)의 기제에 따라 만주어뿐만 아니라 한국어, 몽골어, 돌궐어 등 북방 알타이제어에 폭넓게 받아들여진 것이다. This paper aims to examine the aspect and characteristics of the Manchurian words ending in ‘-se’ which originated from Chinese words ‘X子’. To this end, firstly, the primary list of Manchurian words ‘Xse’ that likely to be correlated to Chinese words ‘X子’ was found and organized in the Manchu dictionary of HMB(1708, 『Yuzhi Qingwen Jian』). And then, this primary words list was classified and the corresponding relation between Manchu ‘-se’ and the Chinese suffix ‘-zi’ was examined by comparing and reviewing Chinese words in 『Yuzhi Zengding Qingwen Jian』(1771). As a result, ‘-se’ was viewed as the grammatical meaning and correspondence of ‘-zi’ to a considerable extent. The words of ‘Xse’ which originated from Chinese words ‘X子’ were widely accepted not only in Manchu but also in northern Altai language such as Korean, Mongolian, and Turkish, according to the mechanism of lexical replication.

      • KCI등재

        Inflammatory Endotypes and Tissue Remodeling Features in Antrochoanal Polyps

        Chen Cai-Ling,Wang Yu-Ting,Yao Yin,Pan Li,Guo Bei,Zhu Ke-Zhang,Ma Jin,Wang Nan,Li Xue-Li,Deng Yi-Ke,Liu Zheng 대한천식알레르기학회 2021 Allergy, Asthma & Immunology Research Vol.13 No.6

        Purpose: The pathogenic mechanisms of antrochoanal polyps (ACPs) remain largely unknown. This study aimed to characterize inflammatory patterns and tissue remodeling features in ACPs. Methods: Inflammatory cell infiltration and tissue edema severity as well as fibrin deposition in ACPs and bilateral eosinophilic and noneosinophilic nasal polyps (NPs) were studied with immunohistochemical and immunofluorescence staining. Cytokine levels in sinonasal tissues were detected with the Bio-Plex assay. The expression of coagulation and fibrinolytic markers was measured using reverse-transcription polymerase chain reaction and enzyme-linked immunosorbent assays. Results: Compared to control tissues and bilateral eosinophilic and noneosinophilic NPs, ACPs had higher levels of neutrophil infiltration and expression of myeloperoxidase (MPO), interleukin (IL)-8 and interferon (IFN)-γ. In total, 94.4% of ACPs demonstrated an eosinophil cationic protein/MPO ratio of < 1, compared to 79.0% of noneosinophilic and 26% of eosinophilic NPs. Principle component and multiple correspondence analyses revealed a neutrophilic and type 1 inflammation pattern in ACPs. Compared to control tissues, edema scores and fibrin deposition were increased, whereas d-dimer and tissue plasminogen activator (tPA) levels were decreased in ACPs and bilateral NPs, with more prominent changes in ACPs even than in eosinophilic NPs. The tPA levels were negatively correlated with IFN-γ, IL-8, and MPO levels in ACPs. Neutrophils were the major cellular source of IFN-γ in ACPs, and the number of IFN-γ+ neutrophils was elevated in ACPs than in control tissues and bilateral eosinophilic and noneosinophilic NPs. Conclusions: ACPs are characterized by the neutrophilic and type 1 inflammation endotype. Neutrophil-derived IFN-γ is associated with reduced tPA production in ACPs.

      • KCI등재

        The Characteristics and Survival Outcomes in Patients Aged 70 Years and Older with Nasopharyngeal Carcinoma in the Intensity-Modulated Radiotherapy Era

        Ya-Nan Jin,Wang-Jian Zhang,Xiu-Yu Cai,Mei-Su Li,Wayne R. Lawrence,Si-Yang Wang,Dong-Mei Mai,Yu-Yun Du,Dong-Hua Luo,Hao-Yuan Mo 대한암학회 2019 Cancer Research and Treatment Vol.51 No.1

        Purpose We aim to examine nasopharyngeal carcinoma (NPC) characteristics and survival outcomes in patients aged 70 years and older in the intensity-modulated radiotherapy (IMRT) era. Materials and Methods From 2006 to 2013, 126 non-metastatic NPC patients aged  70 years who were treated with IMRT +/ chemotherapy were included. Adult Comorbidity Evaluation 27 (ACE-27) was used to measure patient comorbidities. The overall survival (OS) and cancer-specific survival (CSS) were calculated with the Kaplan-Meier method, and differences were compared using the log-rank test. The Cox proportional hazards model was used to carry out multivariate analyses. Results For the entire group, only two patients (1.6%) presented stage I disease, and up to 84.1% patients had stage III-IVB disease. All patients had a comorbidity score of 0 in 24 (19.0%), 1 in 45 (35.7%), 2 in 42 (33.3%), and 3 in 15 (11.9%) patients. The main acute grade during radiotherapy was 3-4 adverse events consisting of mucositis (25.4%), bone marrow suppression (16.7%), and dermatitis (8.7%). After treatment, four patients (3.2%) developed temporal lobe injury. Five-year CSS and OS rates were 67.3% (95% confidence interval [CI], 58.6% to 77.4%) and 54.0% (95% CI, 45.6% to 63.9%), respectively. Five-year OS was significantly higher for ACE-27 score 0-1 than ACE-27 score 2-3 (72.9% and 39.9%, respectively; p < 0.001). Multivariate analyses showed ACE-27 score 0-1 was significantly associated with superior OS (hazard ratio [HR], 3.02; 95% CI, 1.64 to 5.55; p < 0.001). In addition, the rate of OS was higher for stage I-III than that of stage IV, with borderline significance (HR, 1.67; 95% CI, 0.99 to 2.82; p=0.053). But no significant advantage was observed in OS when chemotherapy was used (p > 0.05). Conclusion Our findings suggest IMRT +/– chemotherapy has a manageable toxicity and provides an acceptable survival in patients aged  70 years with NPC. ACE-27 score was significantly associated with survival outcomes in this group population.

      • Three-Port Laparoscopic Exploration is not Sufficient for Patients with T4 Gastric Cancer

        Huang, Hua,Jin, Jie-Jie,Long, Zi-Wen,Wang, Wei,Cai, Hong,Liu, Xiao-Wen,Yu, Hong-Mei,Zhang, Li-Wen,Wang, Ya-Nong Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.19

        Gastric cancer continues to be a leading cause of cancer death. The majority of patients with gastric adenocarcinoma in China present with advanced disease. Ruling out unresectable cancers from an unnecessary "open" exploration is very important. The aim of this study was to assess the value of five-port anatomical laparoscopic exploration in T4 gastric cancer in comparison with three-port laparoscopic exploration and laparotomy exploration. We conducted a retrospective study on 126 patients with T4 stage scheduled for D2 curative gastrectomy based on computed tomography (CT) staging at Department of Gastric Cancer and Soft Tissue Sarcoma, Fudan University Shanghai Cancer Center, from Apr. 2011 to Apr. 2013. Laparotomy exploration (Group I), three-port laparoscopic exploration (Group II) or five-port anatomical laparoscopic exploration (Group III) were performed prior to radical gastrectomy. Accuracy rate for feasibility of D2 curative gastrectomy in laparotomy exploration and five-port anatomical laparoscopic exploration groups was higher than that in the three-port laparoscopic exploration group. Five-port anatomical laparoscopic exploration group had the highest accuracy resection rate (Group I vs Group II vs Group III,92.6% vs78.6% vs 97.7%; p<0.05) and shorter length of hospitalization (Group I vs Group II vs Group III, $9.58{\pm}4.17$ vs $6.13{\pm}2.85$ vs $5.00{\pm}1.81$; p<0.001). Three-port laparoscopic exploration has low accuracy rate for assessing feasibility of D2 curative gastrectomy and five-port anatomical laparoscopic exploration should be performed on patients with T4 gastric cancer.

      • KCI등재

        How Job Stress and Psychological Adaptation Predicting Interpersonal Needs Among Female Migrant Manufacturing Workers in China: A Structural Equation Model

        Wang Rongxi,Yu Xiaoyue,Chen Hui,Hu Fan,XU CHENG,Liu Yujie,Liu Shangbin,Jin Lian,Li Ming,Cai Yong 한국산업안전보건공단 산업안전보건연구원 2023 Safety and health at work Vol.14 No.2

        Background: This study aimed to explore relationships between job stress and psychological adaptation and how they related to interpersonal needs through mood states among female migrant manufacturing workers. Methods: A cross-sectional survey was conducted in 16 factories in Shenzhen, China. Sociodemographic, job stress, psychological adaptation and other psychological information of was collected. Structural equation modeling was performed to delineate the internal relationship between variables. Results: The hypothetical structural equation model exhibited acceptable model fit among female migrant manufacturing workers (c2 ¼ 11.635, df ¼ 2, c2/df ¼ 5.82, p ¼ 0.003, RMSEA ¼ 0.090, CFI ¼ 0.972, SRMR ¼ 0.020). Job stress was directly associated with mood states and interpersonal needs; Psychological adaptation was directly associated with mood states and indirectly associated with interpersonal needs; Bootstrapping tests demonstrated mediation effect of mood states in the way from psychological adaptation to interpersonal needs. Conclusion: Female migrant manufacturing workers who suffered stress from job and the process of psychological adaptation may have worse mood states and workers with worse mood states are more likely to develop unmet interpersonal needs, a proximal factor of suicidal ideation.

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