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河潤卿,金永寬,孫秉淸,申鉉萬,朴美敬 弘益大學校 科學技術硏究所 1996 科學技術硏究論文集 Vol.7 No.1
The octadodecanoxy derivative of the phthalocyanine which has such long hydrocarbon chains around the skeleton of the phthalocyanine was synthesized. First of all, ortho-catechol was treated with 2 moles of 1-bromododecane to yield ortho-didodecanoxybenzene(I). Second, bromination of I resulted in dibromo-didodecanoxy benzene(II) where the para positions to the dodecanoxy groups were brominated. Finally, reaction of II with an excess of CuCN under an N₂atmosphere gave the intermediate dicyano-didodecanoxy-benzene(III), in situ, and futher heating in dry DMF with more CuCN gave the final product, octadodecanoxy derivative of the phthalocyanine. The synthetic method developed herein provides a general way to synthesize the variety of the phthalocyanines which displays many different substituents such as long hydrocarbons around its skeleton and contains a various metal inside of the phthalocyanine.
돼지에서 정맥, 근육 그리고 경구 투여시의 enrofloxacin의 약물동태학
윤효인,김무열,박승춘,조준형,박병권,이내경,노상석,장범수,신광순,조명행 충남대학교 수의과대학 동물의과학연구소 1996 動物醫科學硏究誌 Vol.4 No.-
In order to characterize pharmacokinetic profiles according to route of a new enrofloxacin salt form (Enrotil®), it was given to 4 healthy pigs via oral (p.o.), intramuscular (i.m.) or intravenous (i.v.) administrations at a dose rate of 5 ㎎/㎏ body weight. Enrofloxacin (ENFX) in serum was detected by bioassay using E. coli BE1186 as a test organism. The biological elimination half-lives (t_1/2(β)) of ENFX were 6.76±0.99 h (i.v.), 7.16±2.30 h (i.m.) and 11.45±3.90 h (p.o.), Volume of distribution (Vd) of enrofloxacin was 2.20±0.31 L/㎏ (i.v.), 2.52±0.60 L/㎏ (i.m.) and 1.88±0.33 L/㎏ (i.m.). Mean residence time (MRT) was 8.77±1.26 h after i.v. injection and the maximal concentration time (Tmax) following p.o. and i.m. administration was 0.76±0.09 h and 0.60±0.12 h, indicating a rapid absorption from these routes. Bioavailibility (F) was calculated as 64.1% for p.o. administration and 59.71% for i.m. injections. In summary, the newly formulated enrofloxacin salt form has shown a high water solubility, rapid absorption and large tissue distribution, suggesting a potential antibacterials for oral application on a large scale in veterinary sectors.
溫度變化에 따른 都市固形廢棄物의 堆肥化 過程 比較에 關한 硏究
金丙泰,尹河衍 대진대학교 1993 大眞論叢 Vol.1 No.-
This study was carried out to analysis the degradation rate of the organic materials and the variation of the microorganism population by the temperature changing The object of this study is to suggest foundational data for the application of mechanical composting of urban solid wastes From this study on the comparison of the composting process of urban solid wastes by the temperature changing, the results are as follows 1. In case of the composting index, VS(Volatile Solid), C/N ratio and CO₂evacuation rate in reactor Ⅱ which is aerated with constant aeration rate are higher than reactor I which is autothermal reactor with a constant temperature at 50℃ Microorganism populations of psychrophilic bacteria, mesophilic bacceria and thermophilic bacteria of reactor I are higher than those of reactor II. 2. In case of the degradation of the organic materials, Carbohydrate is degraded actively over 55℃, but lipid and protein are degraded high below 50℃ 3. In first stage of the composting, component of carbohydrate(42.18%) is higher than protein(29.54%) and lipid(19.93%), but component of carbohydrate and lipid decreased during composting because of the high degradation rate. Whereas, component of protein increased because of the low degradation rate.
이춘식,정병윤,하태명,박현건 진주산업대학교 농업기술연구소 2001 農業技術硏究所報 Vol.14 No.-
This study was carried out to investigate the purification effect of wastewater included LAS by electrolysis treatment system. Wastewater included LAS treated electrolysis treatment process, temperature of inner treated system were high than those of this raw wastewater, temperature change was electrolysis oxidation of LAS wastewater both cathode and anode. Electrolysis oxidation was oxidized LAS by oxidants of chlorine and ozone, on the time, according to the result development of treated efficiency on electrolysis contact time.
Reducing Phosphorus Release from Paddy Soil by Coal Ash and Phospho-Gypsum Mixture
이창훈,Young Bok Lee,Hyub Lee,Byung Yun Ha,Pil Joo Kim 한국환경농학회 2005 한국환경농학회지 Vol.24 No.1
As a silicate source to rice, a coal ash was selected and mixed with phosphor-gypsum (50:50, wt wt-1) to reduce the potential of boron toxicity and to supply calcium element. We expected that high con- tent of calcium in this mixture might convert water-soluble phosphorus to less soluble forms and then reduce the release of soil phosphorus to surface runoff. The mixture was applied with the rate of 0, 20, 40, and 60 Mg ha-1 in paddy soil (Nagdong series, a somewhat excessively drained loamy fine sand) in Daegok, Jinju, Korea The mixture reduced significantly water-soluble phosphorus (W-P) in the surface soils by shifting from W-P and Fe-P to Ca-P and Al-P during whole rice cultivation. In contrast with W-P, plant available phosp- horus increased significantly with the mixture application due to high content of phosphorus and silicate in the mixture. The mixture of coal ash and phosphor-gypsum (50:50, wt wt-1) would be a good alternative to reduce a phosphorus export in rice paddy soil together with increasing rice yields.
고착협 내탈립 기계수확 적응 장류⋅두부용 콩 품종 ‘새금’
김현태(Hyun Tae Kim),한원영(Won Young Han),이병원(Byung Won Lee),고종민(Jong Min Ko),이영훈(Yeong Hoon Lee),백인열(In Youl Baek),윤홍태(Hong Tai Yun),하태정(Tae Joung Ha),최만수(Man Soo Choi),강범규(Beom Kyu Kang),김현영(Hyun Yeong K 한국육종학회 2019 한국육종학회지 Vol.51 No.4
The soybean cultivar, ‘Saegeum’, has been developed for preparing soy-paste and tofu. The soybean cultivars ‘Daepung’ and ‘SS98207-3SSD-168’ were crossed in 2003 to obtain ‘Saegeum’. Single seed descent method was used to advance the generation from F3 to F5, and the plant lines with promising traits were selected from F6 to F7 by pedigree method. The preliminary yield (PYT) and advanced yield trials (AYT) were conducted from 2009 to 2010, and the regional yield trial (RYT) was conducted in 12 regions between 2011 and 2013. The morphological characteristics of ‘Saegeum’ were as follows: determinate plant type, white flower, tawny pubescence color, and brown pod color. Flowering and maturity dates were August 2, XXXX and October 17, XXXX, respectively. Plant height, first pod height, number of nodes, number of branches, and number of pods were 79 cm, 18 cm, 16, 2.3, and 44, respectively. The seed characteristics of ‘Saegeum’ were as follows: yellow spherical shape, yellow hilum, and the 100-seed weight was 25.4 g. ‘Saegeum’ was resistant to bacterial pustule and SMV in the field test, and its lodging resistance was mildly strong, whereas its shattering resistance was excellent. The ability of this cultivar to be processed into tofu, soybean malt, and other fermented products was comparable with that of ‘Daewonkong’. The yield of ‘Saegeum’ in the adaptable regions was 3.02 ton ha-1. Thus, ‘Saegeum’ is adaptable to mechanized harvesting because of its high first pod height, as well as lodging and shattering resistance. (Registration number: 5929)
열공형과 비열공형 피질하 혈관성 치매에서 위험인자의 차이에 관한 비교 연구
배희준,정지향,유경호,나덕렬,김상윤,최경규,양동원,손의주,이상도,김재우,박경원,김응규,이재홍,박미영,한일우,함동석,최문성,하충건,최성혜,이애영,이병철,한설희 대한치매학회 2003 Dementia and Neurocognitive Disorders Vol.2 No.2
Backgrounds and Objectives: Vascular dementia is a group of dementing disoders arising from various stroke syndrome. Among these. subcortical ischemic vascular dementia (SIVD) is regarded as a relatively distinct clinical entity. However, MRI patterns of SIVD are not homogenous. In some patients, lacunes are dominant, and in others, subcortical white matter changes are. This study was designed to compare risk factor profiles between SIVD with and without multiple lacunes. Methods: We divided 47 subjects (22 males, mean age. 68 years) recruited from VADAPET (Multicenter Trial For Evaluation Of The Changes In the PET Images Of Subcortical Vascular Dementia Patient) study into two groups one with more than 5 lacunes in deep gray matter (lacune group) and the other with 5 or less(non-lacune group) Clinical characteristics and laboratory findings of two groups were compared. Results: Nineteen of 47 patients (40%) belonged to the lacune group. The lacune and non-lacune groups d d not differ in the following variables: age, hypertension, diabetes mellitus, hyperlipidemia heart disease, history of stroke or TIA, history of trauma or major surgery, family history of hypertension stroke, or dementia, age at diagnosis of dementia, body mass index, white blood cell count, ESR, CRP, fibrinogen, hemoglobin A1C, total cholesterol. LDL cholesterol creatinine, proteinuria, glucosuria, and microhematuria. However, male sex, smoking alcohol. hemoglobin, and HDL cholesterol were possibly associated more with lacune group SIVD than with non-lacune group (p<0 1) Multivariate analyses revealed that smoking, hemoglobin, and HDL cholesterol were independent predictors of SIVD with multiple lacunes Conclusion: Our study suggests that SIVD with multiple lacunes may be significantly different in smoking habits hemoglobin, and HDL cholesterol from SIVD without multiple lacunes.
Reducing Phosphorus Release from Paddy Soil by Coal Ash and Phospho-Gypsum Mixture
Lee, Chang Hoon,Lee, Yong Bok,Lee, Hyub,Ha, Byung Yun,Kim, Pil Joo 한국환경농학회 2005 한국환경농학회지 Vol.24 No.1
As a silicate source to rice, a coal ash was selected and mixed with phosphor-gypsum (50:50, wt wt^(-1)) to reduce the potential of boron toxicity and to supply calcium element We expected that high con-tent of calcium in this mixture might convert water-soluble phosphorus to less soluble forms and then reduce the release of soil phosphorus to surface runoff. The mixture was applied with the rate of 0, 20, 40, and 60 Mg ha^(-1) in paddy soil (Nagdong series, a somewhat excessively drained loamy fine sand) in Daegok, Jinju, Korea The mixture reduced significantly water-soluble phosphorus (W-P) in the surface soils by shifting from W-P and Fe-P to Ca-P and Al-P during whole rice cultivation. In contrast with W-P, plant available phosphorus increased significantly with the mixture application due to high content of phosphorus and silicate in the mixture. The mixture of coal ash and phosphor-gypsum (50:50, wt wt^(-1)) would be a good alternative to reduce a phosphorus export in rice paddy soil together with increasing rice yields.