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      • KCI등재후보
      • SCOPUSSCIEKCI등재

        단일클론 항 γ-Glutamyltrasferase(GCT) 항체를 이용한 혈뇌장벽 내 GGT의 분포에 관한 연구

        이병규,김명곤,신규만,류총근 대한신경외과학회 1995 Journal of Korean neurosurgical society Vol.24 No.3

        γ-Glutamyltransferase(GGT: E.C. 2.3.2.2.) is a glycoprotein enzyme which is involved in glutathione metabolism and amino acid transport through the plasma membrane. It is distributed widely in several organs including liver, kidney, pancrease and brain. GGTs derived from the brain of Wister rats and BALB/c mice were biochemically purified to a specific activity of 4246.2, 862.1 units per mg of protein, a purification folds 93.7, 43.8 and the final yield 65.8, 44.0% respectively. Electrophoretic pattern of purified GGTs from rats and mice brain shows very similar protein fraction each other. We have produced six monoclonal antibodies(GGT-MAb 1-6) against 2-acetamidofluorene treated rat liver GGT. Using these GGT-MAb 1-6 we performed immunohistochemistry(IHC) to study the distribution of GGY isozymes in normal tissues of rat brain and in ncoplastic tissues of human brain. The results indicated that human brain GGT was localized in pericytes of blood-brain barrier, especially in the blood-rich portion of the brain(e.g. cerebellum of rat, meningioma and craniopharyngioma of human). Therefore these MAbs may be used to evaluate the distribution of GGT isozymes in different tissues.

      • Anoxic-oxic 및 Step-feed process에 있어서의 생물학적 질소제거 Modeling

        이철희,박영규,이병대 嶺南大學校 環境問題硏究所 1995 環境硏究 Vol.14 No.2

        본 연구는 WQM MODEL에 의해서 Anoxic-oxic process와 Step-feed process 각 Unit에서의 TN 유출수를 계산하였고 실 처리장의 측정치와 비교분석하였다. Simulation도중에서 bugs나 logic error는 발생하지 않았다. 또한 모든 simulation결과치는 두번 행한 값이고 이 값들은 매우 유사한 값을 나타내어 본 모델이 좋은 재현상을 보이는 것으로 나타났다. 몇 개의 simulation결과치가 실 처리장의 측정치와 다소 차이가 있었으나 이것은 실 처리장의 유입수질의 부족하였기 때문에 발생한 것이라고 생각된다. 그러나 전반적으로는 실 처리장의 측정치와 좋은 상관관계를 보이고 있어 본 모델이 신뢰성을 보이고 있는 것으로 나타났다. 본 모델을 이용하여 Anoxic-oxic process와 Step-feed process의 실 처리장에서 TN유출수를 ±4.92 mg/ℓ안에서 예측 가능함을 나타냈다. Two activated sludge methods of anoxic-oxic and step-feed process were analyzed numerically for the each unit and final TN effluent by WQM MODEL and the results were compared with several measured data from these WWTPs. No bugs and logic error were occurred during simulation work. All of the simulation results tried to two times were obtained and both results were almost same thus this model has good reappearance. A few of simulation results were deviated with measured data because lack of influent water qualities are reported however simulation results have wholly good relationship with measured data. Also each unit of simulation result was kept good realtionship with that of measured data therefore this WQM MODEL has good reliance. Finally, WQM MODEL predicts final TN effluent within±4.92 mg/ℓ.

      • 필기체 문자 인식을 위한 신경회로 시뮬레이션

        이창기,이완규,전병실 전북대학교 전자산업개발연구소 1991 전자산업연구 Vol.2 No.-

        This paper proposed a neural computer architecture for the learning of character pattern recognition categories. The architecture of self-organizations and self-stabilizations is recognition codes in response to arbitrary orderings of many and complex binary input patterns. Top-down attentional and matching mechanisms are critical in self-stabilizing of the code learning process. The architecture embodies a parallel search scheme which update itself adaptively as the learning process unfolds. After learning self-stabilizes, the search process in automatically disengaged. Thereafter input patterns have directly access to their recognition codes without any search. Thus recognition time does not grow as a funtion of code complexity. A novel input pattern can directly access a category if it shares invariant properties with the set of familiar exemplars of that category in the form of learned critical feature patterns, or prototype. Attentional vigilance determines how fine the learned categories will be. If vigilance increases due to an environmental disconfirmation, then the system automatically searches for and learns finer recognition categories. The simulation of this system shows satisfied result in the recognition of the hand written character of hangul.

      • 전기투석에 의한 금속이온 분리에 관한 연구

        李炳哲,朴在奎 홍익대학교 산업기술연구소 2000 産業技術 Vol.10 No.-

        Effect on the temperature, flow rate, and applied stack, voltage on zero-gap electrodialysis cell performance. Permeation of metal ion was increased with increasing temperature and flow rate. The temperature characteristics data were well coincided with Arrhenius type equation. As the applied stack voltage increased, the current density changing rate was increased rapidly with time due to the concentration polarization. It was proposed that not only the distance of electrode but also the flow pattern should be taken as a design factor electrodialysis cell.

      • 식품과 식품포장재 중 첨가물 및 중금속 함량에 관한 연구

        李丙晁,朴澤奎 건국대학교 1980 學術誌 Vol.24 No.2

        A study was carried out on the coloring matters, preservatives and color fixation matters in hall and sausage sampled from 5 companies during the period of two months from August 1, to October 1, 1979, and determined the contents of cadmium and Lead in food packaging materials (PVC) The results were obtained as follows. (1)In ham a mixture of Amaranth and Tartrazine was detected in three (10%), and Amaranth was detected in two (5%) that of Amaranth, Tartrazine and Sunset yellow FCF in one (3.3%) (2)In sausage a mixture of Amaranth auld Tartrazine was found ill 11 (36.7%) that of Amaranth and Sunset Yellow FCF in 9 (30%), Amaranth in 4 (13.3%), Tartrazine 3 (10%) of 30 samples. (3)In ham a mixture of solbic acid and its salts, AF2 was detected in 11 (36.7%) and a mixture of sorbic acid, its salt, AF2 and Nitrofurazone was detected in 9 (30 %) out of 30 samples and that in sausage was a mixture of sorbic acid, its salts and AF2 in 14 (46.7%) and a mixture of sorbic acid, its salt and Nitrofurazone was in 11 (36.7%) out of 30 samples. (4)The concentrations of all the color fixation matter were in the range of 480mg to 2730mg per Kg of samples in ham and of 410mg to 2700mh in sausage (5)The contents of Cadmium and Lead in PVC packaging materials were in the range of 120.5 ㎍/g to 515.3 ㎍/g and 257 ㎍/g to 1.593 ㎍/g respectively.

      • 포스파젠 분리막을 이용한 금속이온의 분리

        李炳哲,朴在圭 홍익대학교 산업기술연구소 1999 産業技術 Vol.9 No.-

        Poly〔bis(trifluoromethoxyethoxyethoxyethoxy)phosphazene〕was casted by dip coating method into membranes supported on porous polypropylene mesh filter sheet for metal separation testing. A solution of Cr^3+, Co^2+, Mn^2+ nitrates was used in diffusion experiments which conducted from 25 to 60℃. Membrane of poly〔bis(trifluoromethoxyethoxyethoxy-ethoxy)phosphazene〕was found to separate Cr ion from Mn and Co ions with separation factors of 2.0 at 60℃. Diffusion activation energy were calculated from diffusion coefficients.

      • Cr-Cu/p-Si MIS型 太陽電池의 製作 및 特性

        羅炳旭,金奎用,李原鎭 慶北大學校 物理化學硏究所 1984 硏究論文集 Vol.5 No.-

        Cr-Cu/p-Si MIS solar cells haveing about 1-㎠ area have been fabricated by sequential vacuum evaporation of Cr and Cu metals on the (111) surface of p-type Si single crystal with a thin interfacial layer of SiO_2. The spectral response measurements and the effects of the oxide layer thickness between Cr and Si-substrate were investigated. Also, The antireflection coating improves signifficantly the conversion effieciency of Cr-Cu/p-Si MIS solar cells. Under AM1 illumination of solar simulator, the parameters of the best cell obtained are open-circuit voltage V_oc=0.5V, short-circuit current I_sc=26㎃, fill factor FF=0.67 and conversion efficiency η=8.7%.

      • 성인 음낭수종의 치료로서 Window Operation의 효용성

        서병욱,박영호,이남규,전윤수,김민의,김영호,송윤섭,구자현 순천향의학연구소 1999 Journal of Soonchunhyang Medical Science Vol.5 No.1

        We intended to determine the usefulness of window operation for adult hydrocele repair. We reviewed medical records of 132 patients from January 1995 to June 1998 with primary hydrocele and evaluated complications and recurrence rates of eversion and/or excision, plication, and internal drainage technique. Recurrence rate was highest in internal drainage technique as 85.2%, and those of eversion and/or excision and plication technique were 1.3% and 4%, respectively. Complication rate was highest in eversion and/or excision technique, and lowest in internal drainage technique. Although complication rate was lowest in window operation, this operation could not be successful due to high recurrence, and we suggest that this operation should be abandoned for hydrocele repair.

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