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이경지 ( Kyung Ji Lee ),이안희 ( An Hi Lee1 ),김진아 ( Jea Na Kim ),김형민 ( Hyoung Min Kim ),이교영 ( Kyo Young Lee ) 대한임상종양학회 2009 Korean Journal of Clinical Oncology Vol.5 No.2
체성 연부 조직에 생기는 평활근육종은 매우 드물다. 66세 남자 환자가 방사선 소견상 경계가 좋은 양성 종양이 의심되어 절제술을 시행 받았다. 육안조직소견상 경계가 좋은 둥근 종괴이나, 현미경 소견에서 세포충실도가 증가되고 부분적으로 중증도의 핵이형성을 보였다. 또한 면역조직화학염색상 Smooth muscle actin과 Desmin에 동시에 양성이어 평활근세포 기원으로 생각되었다. 저자들은 괴사가 없고 유사분열은 단 한 개만이 관찰되었으나 중증도의 핵이형성을 보였기에 평활근육종으로 진단한 증례를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Leiomyosarcoma of somatic soft tissue is a rare tumor compared with retroperitoneal lesion. We report a case of a leiomyosarcoma of the somatic soft tissue in a 66-year-old man. He presented as an enlarging mass in the left thigh for eight months. Radiologic examinations revealed a well defined round mass, suspicious of benign tumor, such as hemangioma or leiomyoma. He underwent surgical resection. The mass was 3.0 cm in diameter, and it was confined within adductor longus muscle without any connection to adjacent neurovascular bundles. Histologic examination showed moderately cellularity and focal marked atypia with a fascicular growth pattern of spindle cells showing blunt ended nuclei. In addition, the proliferation index was 2~3% by immunohistochemistry using monoclonal antibody MIB-1. But only one definite microscopic mitotic feature was found. Although it showed low mitotic activity without necrosis, this case was diagnosed leiomyosarcoma according to marked cellular atypism.
문경지(Kyung Ji Moon),이명철(Myung Chul Lee),홍우평(Upyong Hong),노수림(Soo Rim Noh),박창훈(Chang Hoon Park),한경훈(Kyung Hun Han) 대한운동학회 2021 아시아 운동학 학술지 Vol.23 No.3
[OBJECTIVES] The present study is aimed at observing the physiological response imagery running with an avatar in 3D virtual reality (VR) and to explore the differences in physiological responses between imagery running with and without an avatar in 3D VR. [METHODS] We randomly assigned 32 healthy adults to either a group with Avatar (n = 19) or a group without (n = 13). The group with avatar performed imagery exercise with an avatar in 3D VR and the group without Avatar performed it without an avatar in 3D VR. Both groups were instructed to mentally imagine performing running in VR without executing actual physical movements. We recorded electro-physiological data before, during, and after the 20-min intervention. We also measured the participants’ level of presence and intensity of experienced cybersickness. [RESULTS] In the group with Avatar, all physiological responses increased from the resting to the intervention period. The group with Avatar also showed a higher level of presence and fewer cybersickness symptoms than the group without Avatar. [CONCLUSIONS] The results suggest imagery running with an avatar in 3D VR might be effective as an alternative exercise.
편평세포암종으로 오인된 와르틴 종양의 세침흡인 세포소견 -증례 보고-
이경지,정찬권,이아원,강창석,이교영,Lee, Kyung-Ji,Jung, Chan-Kwon,Lee, Ah-Won,Kang, Chang-Suk,Lee, Kyo-Young 대한세포병리학회 2005 대한세포병리학회지 Vol.16 No.2
We report a case of Warthin's tumor of the parotid gland in a 53 year old man, which is incorrectly diagnosed as squamous cell carcinoma. Fine needle aspiration cytology(FNAC) smear obtained from the right parotid gland revealed scattered epithelial cell clusters or nests in a diffuse inflammatory and necrotic background. Some epithelial cells had squamoid appearance showing variable sized bizarre shaped nuclei. They had abundant of dense eosinophilic keratinized cytoplasm. Occasionally, parakeratotic cells were also present. These cytologic findings with significant atypia and necrotic background made diagnosis as squamous cell carcinoma. But, the resection specimen from this patient showed classic Warthin's tumor in addition to abundant areas of inflammation and squamous metaplasia. Metaplastic or infarcted Warthin's tumor in the salivary gland may be confused with false positive diagnosis of malignancy on FNAC. Therefore, cytopathologist should have adequate awareness of potential of erroneous diagnosis in FNAC of Warthin's tumor.
췌장의 점액 낭샘암종의 세침흡인 세포소견 -1예 보고-
이경지,이교영,강창석,심상인,이아원,Lee,, Kyung-Ji,Lee, Kyo-Young,Kang, Chang-Suk,Shim, Sang-In,Lee, Ah-Won 대한세포병리학회 2005 대한세포병리학회지 Vol.16 No.2
Mucious cystic neoplasm of pancreas is a cystic neoplasm composed of columnar, mucin-producing epithelium and is supported by ovarian-type stroma. The key to the cytologic evaluation of pancreatic cystic lesions is to recognize the cytologic components as being diagnostic of a mucin-producing cystic neoplasm, as all of these neoplasms need to be resected. We report the use of fine needle aspiration cytology in the diagnosis of an invasive mucinous cystic carcinoma confirmed by partial pancreatectomy. The cytologic specimen showed a abundant mucin background and sheets or papillae of neoplastic cells. There are mucin-containing columnar cells that show a variable degree of cytologic atypia.
우경지 ( Gyeong-ji Woo ),이혜린 ( Hye-rin Lee ),김윤정 ( Yoonjung Kim ),김혜진 ( Hye-jin Kim ),박덕영 ( Deok-young Park ),김진범 ( Jin-bom Kim ),오경원 ( Kyung-won Oh ),최연희 ( Youn-hee Choi ) 대한예방치과·구강보건학회 2018 大韓口腔保健學會誌 Vol.42 No.4
Objectives: The Korea National Health and Nutrition Examination Survey (KNHANES) is a national surveillance system that has been assessing the health and nutritional status of Koreans since 1998. Based on the National Health Promotion Act, the surveys have been conducted by the Korea Centers for Disease Control and Prevention (KCDC). Methods: An oral examination as part of The National Health and Nutrition Examination was proposed to calculate the sample design and survey participation. The surveying system was presented by classifying the measurement environment, screening, and survey items by year, and the merits and limitations of using the data were suggested by examining the status of survey quality management and the process of disclosing raw data. Results: This nationally representative cross-sectional survey samples approximately 10,000 individuals each year and collects information on oral examinations and oral health interviews. Data for the oral health component of KNHANES was obtained to assess the oral health status of Koreans and determine the prevalence of dental caries and periodontitis. The oral health data quality control of KNHANES was composed of three parts: “Education Program” and “Field Training Program” for quality control of oral health examiners (dentists) by the professional academy, and “Data management” by the KCDC. After completion of the three-step data check, the indicators of dental caries, periodontal disease, and oral health behavior were published in the National Health Statistics. Conclusions: To achieve the goals of oral health indicators, we will continue to monitor so that we can use it as basic data for oral policies and carry out various linkage analyses related to oral diseases.
소아의 견갑골에 생긴 투명세포연골육종 - 1예 보고 -
이경지,이안희,김진아,김형민,이교영,Lee, Kyung-Ji,Lee, An-Hi,Kim, Jean-A,Kim, Hyoung-Min,Lee, Kyo-Young The Korean Musculoskeletal Tumor Society 2009 대한골관절종양학회지 Vol.15 No.2
투명세포연골육종은 모든 연골육종의 2%를 차지하는 매우 드문 저등급성 종양이다. 주로 긴뼈의 뼈끝에서 발생하며 대퇴골과 상완골의 근위부에서 가장 흔하고, 견갑골을 포함한 납작뼈에는 드물다. 25-50세 사이의 연령에서 호발하며, 20세 이전의 발생은 흔치 않다. 조직학적으로 종양 세포는 소엽상 무리를 지어 관찰되며, 투명하고 풍부한 세포질을 특징적으로 가진다. 저자들은 8세 여아의 견갑골에서 발생된 투명세포연골육종을 보고하고자 한다. Clear cell chondrosarcoma is a rare, low-grade variant of chondrosarcoma that comprises approximately 2% of all chondrosarcomas. This tumor usually involves the epiphysis and epimetaphysis of long bones, especially the proximal part of the femur or humerus, whereas involvement of the scapula is rare. It occurs at any age, but the peak is third to fifth decade, and is rarely seen in the first and second decades of life. Histologically, tumor cells with abundant clear cytoplasm and benign giant cells are usually found. We report on a case of clear cell chondrosarcoma of the scapula in an 8-year-old girl.
수기 액상세포검사 $Liqui-PREP^{TM}$의 세포보존력 평가 및 뇌척수액 세포검사에의 적용: 세포원심분리법과의 비교
박경신,이경지,정찬권,이대형,조빈,이연수,심상인,이교영,강창석,Park, Gyeong-Sin,Lee, Kyung-Ji,Jung, Chan-Kwon,Lee, Dae-Hyoung,Cho, Bin,Lee, Youn-Soo,Shim, Sang-In,Lee, Kyo-Young,Kang, Chang-Suk 대한세포병리학회 2007 대한세포병리학회지 Vol.18 No.1
Cerebrospinal fluid (CSF) cytology is an effective tool for evaluating diseases involving the central nervous system, but this technique is usually limited by its low cellularity and poor cellular preservation. Here we compared the manual liquid-base $Liqui-PREP^{TM}$ (LP) to the cytospin (CS) with using a mononuclear cell suspension and we applied both methods to the CSFs of pediatric leukemia patients. The cytopresevability, in terms of cell yield and cell size, and the clinical efficacy were evaluated. When 2000 and 4000 mononuclear cells were applied, LP was superior to CS for the cell yield, 16.8% vs 1.7% (P=0.001) and 26.2% vs 3.5% (P=0.002), respectively. The mean size of the smeared cells was 10.60 ${\mu}m$ in the CS, 5.01 ${\mu}m$ in the LP and 6.50 ${\mu}m$ in the direct smear (DS), and the size ratio was 1.7 (CS to DS), 0.8(LP to DS) and 2.1 (CS to LP), respectively. As compared to the cells in the DS, the cells in the CS were significantly enlarged, but those in the LP were slightly shrunken. Upon application to 109 CSF samples, 4 were diagnosed as positive for leukemia (positive), 4 had atypical cells and 101 were negative by CS; 6 were positive, one had atypical cells and 102 were negative by LP. For six cases, in which 4 were positive for leukemia and 2 of 4 had atypical cells by CS, they were positive by LP and they were also confirmed as positive according to the follow-up study. Three cases diagnosed as atypical cells (two by CS and one by LP), were confirmed as negative. In conclusion, these results suggest that LP is superior to CS for the cytopresevability and for rendering a definite diagnosis of cerebrospinal fluid.
폐에 발생한 염증성 근섬유모세포종양의 세침흡인 세포소견 -1예 보고-
박경신,이경지,이선미,이교영,심상인,강창석,이연수,Park, Gyeong-Sin,Lee, Kyung-Ji,Lee, Sun-Mi,Lee, Kyo-Young,Shim, Sang-In,Kang, Chang-Suk,Lee, Youn-Soo 대한세포병리학회 2006 대한세포병리학회지 Vol.17 No.1
Inflammatory myofibroblastic tumor (IMT), normally referred to as inflammatory pseudotumor, is a fairly rare condition. Fine needle aspiration cytology (FNAC) of IMT has only rarely been reported. Here, we describe one such case of pulmonary inflammatory myofibroblastic tumor. A 30-year-old man presented with a 2.8cm-sized mass in his lung. Chest CT revealed a well defined, poorly enhancing mass. FNAC showed some fascicular or swirled clusters of spindle cells, admixed with occasional inflammatory cells and foamy histiocytes. The majority of the tumor cells evidenced bland, elongated nuclei, but infrequent pleomorphic nuclei. Some of the tumor cells evidenced nuclear grooves and intranuclear inclusions. Although the cytological differentiation of IMT from malignant lesions is not immensely problematic, due to the general paucity of cytological and nuclear atypia, a definite cytological diagnosis of IMT cannot be rendered simply by FNAC. Therefore, a diagnosis of IMT may be suggested via exclusive diagnosis.
조성민,표성운,박지영,김진아,이경지,Cho, Sung-Min,Pyo, Sung-Woon,Park, Ji-Young,Kim, Jean-A,Lee, Kyung-Ji 대한악안면성형재건외과학회 2009 Maxillofacial Plastic Reconstructive Surgery Vol.31 No.4
Adenoid cystic carcinoma(ACC) is the second most common malignant neoplasm in the salivary gland. In spite of ACC shows slowly growing nature, it is sometimes highly detrimental that it readily invades adjacent tissues and metastasize to distant organs at the early stage of disease. Hence, treatment outcome may be misfortunate due to wide regional infiltration, pathognomonic perineural spread and the tendency of hematogenous metastasis. We present a unusal case of ACC of the scalp in which the patient initially presented with bumpy mass of the scalp who had been diagnosed as the primarily developed ACC of the right hard palate that extended to infratemporal fossa, nasal cavity, and paranasal sinuses and had been treated by total excision and post-operative chemotherapy and radiation therapy for 10 years ago. Although this lesion occured at the scalp, which is a frequent site of primary dermatologic ACC, its histomorphology was the same with that of previous tumor. Complete clinical examination showed no recurrence sign at the primary site and suggested the scalp as a sole treatment failure site. Accordingly, it would be reasonable to consider the present case as either a scalp metastasis or a second primary lesion of salivary gland ACC.