위장관 간질종양의 임상 및 병리학적 고찰

김영호,장우영,이순진,손희정,최규완,도재혁,백승운,이준행,이풍렬,이종철,박철근,임윤정,김갑철,김재준,임효근 대한소화기학회 2001 대한소화기학회지 Vol.37 No.3

Background & Aims: Gastrointestinal stromal tumor (GIST) constitutes primary nonepithelial neoplasms of the gastrointestinal tract and includes most tumors previously designated as leiomyomas/leiomyosarcomas. GIST is pathologically divided into benign, borderline and malignanct tumor. This study was carried out to delineate the clinical and pathologic features of GIST and to establish the features predicting malignancy. Methods: Clinicopathologic data of 84 patients who had GIST from 1995 to 1999 were reviewed. Results: The subjects were 42 men and 42 women, and their mean age was 59.3±13.2 years. We located fifty-two tumors in the stomach, 28 tumors in the small intestine and 4 tumors in the colorectum years. Histopathology revealed benign tumors in 23 of the 84 patients, borderline tumors in 22, malignant tumors in 39. The average size of tumors was 6.23 cm in diameter (range, 0.6-26 cm). Metastasis was noted in 15.5% of the patients at diagnosis. On endoscopy, ulceration was more common in malignancy. Endsonographic findings except size were not significant statistically. On contrast enhanced computed tomography, malignancy showed more irregular shape and variable attenuation than benign lesions, which seemed to be valuable factor. Conclusions: The variables predicting malignancy were large tumor size (≥5 cm), location of the colorectum, palpable abdominal mass, ulceration on endoscopy, and less uniformity in shape and variable attenuation on computed tomography.

GG-38 : Minimal invasive surgery (LESS) for huge cystic adnexal tumors in whole abdomen

( In Young Choi ),( Ji Hye Lee ),( Mi Hyun Park ),( Ji Kwoun Park ),( Jeong Kyu Shin1 ),( Won Jun Choi1 ),( Soon Ae Lee ),( Jong Hak Lee ),( Won Young Paik ) 대한산부인과학회 2014 대한산부인과학회 학술대회 Vol.100 No.-

Laparoendoscopic single-site surgery (LESS) is helpful if not an evidence of suspicious malignancy in huge adnexa tumors. This approach might be reasonable alternative to conventional laparoscopic surgery. We report two cases with LESS for huge cystic adnexal tumors in whole abdomen. A 58 years old multigravida woman in menopause underwent removal of a huge cystic adnexal mass that occupied her entire abdomen by LESS.(ca.5200ml aspiration) A 15 years old single nulligravida woman had a huge cystic adnexal tumor in whole abdomen reaching to the level of the xyphoid process. A needle through the transumbilical single port was inserted directly under the mass. Subsequently, 8000 ml of cystic fluid was aspirated without spillage.

흰쥐에서 가시오가피 발효물의 단회 및 반복투여 독성평가

조주현(Ju-Hyun Cho),박인재(In-Jae Park),백순옥(Soon-Ok Baik),최수영(Soo-Young Choi),최구희(Goo-Hee Choi) 한국식품과학회 2014 한국식품과학회지 Vol.46 No.2

본 연구에서는 사용된 가시오가피 영지버섯 발효물과 가시오가피 상황버섯 발효물에 대한 열수추출물을 최고 2 g/kg의 농도로 단회 투여한 SD-rats에 체중 변화, 임상증상 등에서 어떠한 독성도 관찰할 수 없었으며, 1 g/kg 이하의 농도로 4주간 반복 투여한 SD-rats에서도 체중변화, 임상증상, 장기 무게, 혈액학적 성상, 혈액생화학적 성상 등에서 어떠한 독성과 비정상적인 소견을 관찰할 수 없었다. 따라서, 본 연구의 결과로 볼 때 가시오가피 영지버섯 발효물 열수추출물(FM-5111)과 가시오가피 상황버섯 발효물 열수추출물(FM-5131)은 본 연구에서 사용한 농도 내에서의 안전성을 확인할 수 있었다. 황 함유 아미노산의 결핍은 여러 가지 간질환 등의 증상을 야기한다(27). 또한, Choi와 Ahn(28)은 오가피 부위별 50% (v/v) 메탄올 추출액의 전자공여능은 줄기 추출물에서 90.21%, 뿌리 추출물에서 85.71%로 높은 활성을 보고하여 오가피의 항산화능을 규명하였다. 따라서, 본 연구에 사용된 시료 또한 항산화능과 같은 기능성을 가질것으로 사료되며, 추가 연구로 아미노산 분석을 통해 황 함유 아미노산의 함량 변화를 분석하고 간 기능 개선 효능을 평가하여 안전성이 확보된 기능성 식품소재 개발 연구를 진행할 계획이다. In this study, the products of Acanthopanax senticosus fermentation were derived from the mycelia of 2 mushrooms, Ganoderma lucidum and Phellinus linteus, to determine their safety in Sprague-Dawley rats. Rats were orally administered the water extracts of A. senticosus fermentation products with G. lucidum (FM-5111) or P. linteus (FM-5131) at dose levels of 0.5, 1.0, or 2.0 g/kg for the single-dose toxicity test and 0.25, 0.5, or 1.0 g/kg for the repeated-dose toxicity test. There were no significant differences in body weight gain, feed intake, or water consumption between control and FM-5111- or FM-5131-treated rats. Hematological and blood biochemistry analysis revealed that none of the investigated parameters were affected by the A. senticosus fermentation products, and no remarkable lesions were observed upon histopathological analysis. We conclude that the A. senticosus fermentation products obtained from mushroom mycelia are safe for long-term administration and could be considered as multi-functional nutrients for the improvement of liver function and immunity.

유아의 적응에 관련된 아버지 변인

박순태(Park, Soon Tai),최영신(Choi, Young Shin),김영희(Kim, Yeong Hee) 한국유아교육·보육복지학회 2013 유아교육·보육복지연구 Vol.17 No.2

본 연구에서는 유아의 적응에 관련된 아버지 변인을 밝히고자 아버지의 원가족 경험, 성격특성, 결혼만족도, 직장만족도가 아버지의 양육참여 및 유아의 적응에 미치는 영향을 알아보기 위해 유치원에 다니는 아버지 327명을 대상으로 분석하였다. 연구결과는 다음과 같다. 첫째, 유아의 적응과 관련된 아버지 변인(아버지의 성격특성, 결혼만족도, 직장만족도, 아버지 양육참여)에서 아버지의 성격특성이 유아의 적응에 영향을 미치는 가장 중요한 변인으로 나타났다. 둘째, 아버지의 원가족 경험과 성격특성은 아버지의 결혼만족도에 직접적인 영향을 미쳤고, 아버지의 원가족 경험이 성격특성에 미치는 영향은 유의하지 않았다. 셋째, 아버지의 성격특성은 결혼만족도, 직장만족도와 양육참여에 직접적인 영향을 미쳤다. 넷째, 아버지의 성격특성과 결혼만족도는 양육참여에 직접적인 영향을 미쳤고, 결혼만족도를 통해 유아의 적응에 간접적인 영향을 미쳤다. 그러나 아버지의 직장만족도가 양육참여에 미치는 영향은 유의하지 않았다. 다섯째, 아버지의 결혼만족도, 양육참여, 직장만족도는 유아의 적응에 직접적인 영향을 미쳤다. 마지막으로 아버지의 성격특성은 유아의 적응과 관련된 가장 중요한 변인이며, 유아의 적응과 관련된 아버지 변인들은 서로 다른 경로를 통해 유아의 적응에 영향을 미친다는 것이 본 연구를 통해 밝혀졌다. 따라서 아버지의 성격특성을 고려하여 아버지의 양육참여 및 결혼만족도를 증가시키는 것이 필요함이 시사되었다. The purpose of this study was to examine the effect that father's experience in family of origin, personality characteristic, marital satisfaction, and work satisfaction have on father's participation in parenting and young children's adjustment. The subject of this study consisted of 327 fathers whose young children were attending kindergartens. The results of analysis were as follows; First, this study had a meaningful implication that father's personality characteristic was the most important determinant that was related to young children's adjustment. Secondly, it found that father's experience in family of origin, father's personality characteristic had a direct effect on young children's adjustment, but direct effect that father's experience in family of origin had on personality characteristic was not meaningful. Third, it showed that father's personality characteristic had a direct effect on marital satisfaction, work satisfaction, and participation in parenting. Fourth, it found that father's personality characteristic and marital satisfaction had a direct effect on participation in parenting, but direct effect that father's work satisfaction had on work satisfaction was not meaningful. Fifth, father's marital satisfaction, participation in parenting and work satisfaction appeared to have a direct effect on young children's adjustment. In conclusion, this study had a meaningful implication that father's personality characteristic was the most important determinant that was related to young children's adjustment, and father's experience in family of origin, personality characteristic, marital satisfaction, and work satisfaction, father's participation in parenting might influence young children's adjustment through many different kinds of paths.

Sea water intrusion in the coastal area of Cheju volcanic island, Korea

Soon Hak Choi(崔淳學),Young Ki Kim(金永琪),Dong Young Lee(李東瑛) 대한자원환경지질학회 1991 자원환경지질 Vol.24 No.3

濟州島는 火山岩과 火山碎屑性堆積層으로 形成된 韓半島에서 가장 큰 섬이다. 地形은 低地帶로 玄武岩이 넓게 分布하며 섬 中央에는 1950m의 火山이 우뚝 솟아 있으며 정상에는 火山噴出에 依해 形成된 火口가 存在한다. 地表水의 流出은 대단히 빈약하여 用水利用은 地下水와 湧出水에 거의 依存한다. 本 島에는 約 1650여개소의 地下水開發孔이 있는데 대부분 1,000~2,000㎥/day의 産出이 可能하다. 근래에 와서 地下水利用增大에 따라 海岸 인접지역 特히 東部地域中 一部에서는 海水侵入現象이 일어나고 있다. 이 地域의 地形은 아주 平坦하고 地下水位도 海水面 가까이에 位置하여 지하수의 과잉 揚水는 결국 海岸으로부터 最高 6km 내륙까지 海水侵入을 초래하게 되었다. 이러한 문제를 해결하기 爲하여서는 長期 水理化學的인 감시체계망 설치가 무엇보다도 必要하다. Cheju is the biggest island in Korean peninsula, consisted entirely of volcanic rocks and pyroclastic sediments. The topography is characterized by wide basalt plain in the low altitude, but at the center of island, basalt volcano rises 1,950m above sea-level. Surface drainage is very poor, therefore water supply has been dependent on ground water and natural springs. There are about 1,650 production wells and most of them yield 1,000~2,000㎣/day. According to increase of ground water use, saline water is intruded in the low altitude of coastal area. Specially in the eastern coastal area, the topography is extensively flat and the level of ground water is very close to sea-level, at which overuse of ground water has brought saline intrusion up to maximum 6km far from the coast. Hydrochemical monitoring on this salt water intrusion is now undertaken on long term base.

Effect of Sulfur Enriched Young Radish Kimchi on the Induction of Apoptosis in AGS Human Gastric Adenocarcinoma Cells

Kun-Young Park,Soon-Sun Bak,Chang-Suk Kong,Sook-Hee Rhee,Chi-Woong Rho,Nak-Ku Kim,Keyng-Lag Choi 한국식품영양과학회 2007 Preventive Nutrition and Food Science Vol.12 No.2

The effects of young radish (YR, yeolmu in Korean) on the induction of apoptosis were examined in AGS human gastric adenocarcinoma cells. The young radish kimchi (YRK) were made of YR cultivated in the soil without (Control YR kimchi: C-YRK) and with 1,818 g/m3 sulfur (Sulfur YR kimchi: S-YRK), respectively. Methanol extracts from S-YRK exhibited higher inhibitory effect on the growth of AGS human gastric adenocarcinoma cells in a time dependent-manner compared to C-YRK at the same concentration. 4,6-diamidino-2-phenylindole (DAPI) staining showed that S-YRK induced apoptosis accompanied by the increased Bax but decreased Bcl-2 in mRNA expression. Moreover, S-YRK decreased the levels of cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS) mRNA expressions. The results suggested that S-YRK cultivated in the presence of sulfur elicited stronger anticancer activity than C-YRK in vitro. Dietary intakes of S-YRK may be beneficial to decrease the risk of cancer.

Two lepidopterous Insect pests Infested the Cones of Abies koreana in Jeju

Young-Min Shin,Jong-Woo Nam,Ik-Je Choi,Soon-ku So,Min-Jung Joo,Yong-Chan Cho,Bon-Yeol Koo,Bong-Kyu Byun,Il-Kwon Kim 한국응용곤충학회 2014 한국응용곤충학회 학술대회논문집 Vol.2014 No.10

In the present study, we report two lepidopteran pests on the cones of Abies koreana E. H. Wilson; Cydia sp. of Tortricidae and Dioryctria abietella Denis et Schiffermüller of Pyralidae. Larvae of these species bored tunnels inside the immature cones of the host plant. Damaged cones are easy to spot by reddish brown excretion from the pest entry holes, and the cones severly damaged by the larvae becomes crooked. Damage rate on the cones reached up tp 71% from the collection site. Regarding the two pests, some basic information such as collection records, morphological characters, and ecology were provided.

An Intelligent Eddy Current Signal Evaluation System to Automate the Non-Destructive Testing of Steam Generator Tubes in Nuclear Power Plant

Soon Ju Kang,Chan Ho Ryu,In Soon Choi,Seong Soo Choi,Baeng Jae Choi,Young Ill Kim,Kil Yoo Kim,Young Hwan Hur,Hee Gon Woo 대한전자공학회 1992 대한전자공학회 학술대회 Vol.1992 No.10

This paper describes an intelligent system to automatic evaluation of eddy current(EC) signal for inspection of steam generator(SG) tubes in nuclear power plant. Some features of the intelligent system design in the proposed system are : (1) separation of representation scheme for event capturing knowledge in EC signal and for structural inspection knowledge in SG tubes inspection; (2) each representation scheme is implemented in differnt methods, one is syntactic pattern grammar and the other is rule based production. This intelligent system also includes an data base system and an user interface system to support integration of the hybrid knowledge processing methods. The intelligent system based on the proposed concept is useful in simplifying the knowledge elicitation process of the rule based production system, and in increasing the performance in real time signal inspection application.

Analysis of Asian Dust Events in Korea between 1997 and 2005

Choi, Soon-Ho,Choi, Yongjoo,Ghim, Young Sung Korean Society for Atmospheric Environment 2013 Asian Journal of Atmospheric Environment (AJAE) Vol.7 No.2

The characteristics of Asian dust (AD) in Korea between 1997 and 2005 were investigated, focusing on peak 1-hour $PM_{10}$ concentrations during AD events at seven cities over the Korean Peninsula. The frequency of AD events decreased from Seoul to Busan, indicating the major pathway of AD in Korea was from northwest to southeast. AD events were most frequent in 2001 while peak concentrations during AD events were much higher in 2002. Recent works show that the trajectories from northerly directions increased during the 2000s and later (Chun, 2009; Kim, 2008). In this work, the fraction of trajectories from the northwest was the largest on the whole, although trajectories from each direction varied by city and year. It is presumed that high concentrations of $PM_{10}$ during AD events are generally associated with trajectories from the northwest rather than from the source region.

Development of Bioartificial Ligament for ACL Reconstruction

Young-Kwon Seo,Kyung-Min Choi,Soon-Yong Kwon,Hwa-Sung Lee,Yong-Soon Park,Kye-Yong Song,Doo-Hoon Lee,Young-Jin Kim,Jung-Keug Park 한국생물공학회 2005 한국생물공학회 학술대회 Vol.2005 No.4