농촌지역 노인들의 우울증상에 관련된 요인들의 특성

송미숙,전기홍,송현종,김정은,박승구,신상건,이동훈,정성현,최연주,최완철,최민규,황재철,홍지만 아주대학교 1997 아주의학 Vol.2 No.2

This study was performed to identify risk factors for depression among the elderly in a rural area. A survey was done for the elderly living in Gosam-myenn, Ansung-kun during the period of July 28, 1997 and July 30, 1997. Demographic and sodoeconornic characteristics, and functional and health Status were assessed using a structured questionnaire, and the level of depression was measured by GDS score. The data obtained were analyzed by frequencies, percentage, t-test, ANOVA, and multiple regression, and the results were as follows: 1. The total sample consisted of 133 elderly. Of them, 47 elderly (35.4%) showed significant depressive Symptoms. 2. The GDS score was the highest for the group over 85 years of age (p < 0.05). Those living alone or widowed showed lower GDS score than those living with someone or married (p < 0.05). 3. The GDS score was the highest in the absolutely dependent group, followed by the partially dependent group, and the independent group (p < 0.01). The elderly who perceived their health Status as excellent showed the lowest GDS score. In contrast, those who had more than five chronic diseases showed the highest GDS score. 4. The elderly receiving financial and emotional support from their family or friends showed lower GDS score compared to those without any support. 5. The economically dependent group showed higher GDS score than that of independent group. 6. The elderly who involved in leisure activities showed lower GDS score than those without any involvement. 7. In terms of risk factors for depression, we found that perceived health Status, subjective economic Status, leisure activities, living arrangement and financial support were inversely associated with GDS score, whereas labor support was positively associated with GDS score. Based upon the above findings, this study suggests that these risk factors for depression in the elderly should be taken into consideration for a comprehensive mental health program for the elderly living in the rural area.

급성 심근경색증에 동반된 승모판 폐쇄부전증의 임상적 특징

정상만,조영일,조화상,유광하,송기호,인행환 건국대학교 의과학연구소 1997 건국의과학학술지 Vol.- No.7

급성 심근경색증에 동반된 승모판 폐쇄부전증의 임상적 특징

정상만,조영일,조화상,유광하,송기호,인행환 건국대학교 의과학연구소 1997 건국의과학학술지 Vol.7 No.-

The early detection and proper management of mitral regurgitation(MR) associated with acute myocardial infarction(MI) is very important to improve the clinical course and outcome of disease. The change of left ventricular shape and regional function, papillary muscle rupture are major determinant of the existence and severity of MR. We performed 2D and M mode echocardiography of 28 patients at the early stage of acute MI to evaluate the existance and degree of MR and its pathogenetic factor. Significant MR occured in 12 (42.9%) patients. In the group of MI with MR, the inferior MI was frequent (7 case) than anterior MI (5 case) comparing to the patient group of MI without MR (inferior MI : 6 case, anterior MI : 10 case) (p<0.01).The left ventricular end diastolic dimension(LVEDD), end systolic dimension (LVESD) and left atrial dimension (LAD) were significantly increased in MI with MR than MI without MR (LVEDD : 57.3 ±8.6 vs 46.4 ±9.2, p<0.05 ; LVESD : 52.9 ±9.2 vs 38.3 ±7.4, p<0.01 ; LAD : 45.4 ±3.8 vs 37.7 ±3.7, p<0.05).However, the ejection fraction was not different between two group two groups. These datas showed that MR was more frequent in inferior MI and the hemodynamic derangement was more serious in acute MI with MR.

한국인 안검의 생체계측지

박동만,송중원,한기환,강진성 大韓成形外科學會 1990 Archives of Plastic Surgery Vol.17 No.5

Plastic surgeons who frequently deal with trauma and deformity of the eyelids and orbits, need have an abundant knowledge of the accurate anatomical morphology and acceptable proportion of them. The normal value of the anatomical morphology and function of the eyelid has not yet been standardized in Korea. The authors measured anthropometry of normal Korean eyelids and statistically analysed in 2,151 individuals including 1,078 male and 1,073 female. Statistical analysis of these measurements offers valuable information about the chronological growth, size, and shape of healthy Korean eyelids. The results are as follows : 1. There was no significant statistical difference between the right and left sides in all measurements. 2. The growth of the eyelid reached the adult level at about 20 years of age and then the growth can be divided into 3 patterns, the first one slowly increased, the seconded one was a stationary, and the last one slowly decreased. 3. The following statistics were recorded for males and females. The cornea-lateral canthal distance was 7.9mm and 7.3mm, the diameter of the cornea was 13.8mm and 13.6mm cornea-medial canthal distance was 7.8mm and 7.5mm the horizontal dimension of the palpebral fissure was 29.7mm and 28.4mm, the vertical dimension of the palperbral fissure was 7.9mm and 8.0mm, the slant of the palperbral fissure was 9.5 degrees an 10.6 degrees, the intercanthal distance was 36.5mm and 37.2mm, the width of the glabella was 24.4mm,. and 24.1mm, the interpupillary distance was 66.1mm and 63.9mm, the ectocanthion-superior margin of the palpebral fissure distance was 14.9mm and 14.2mm, the endocanthion-superior margin of the palpebral fissure distance was 14.9mm and 14.2mm, the height of the opened upper eyelid was 10.3mm and 10.0mm, the height of the closed upper eyelid was 18.2mm and 18.1mm, levator function by the Berke's method was 16.2mm and 15.6mm, MLD was 7.2mm and 7.1mm, and MRD1, was 2.7mm and 2.6mm respectively. 4. The vertical dimension of the palpebral fissure, slant of the palpebral fissure, and height of the double eyelid fold were greater in females than males. The intercanthal distance and width of the glabella was nearly the same in males and females and other measurements were greater in males than females. 5. A double eyelid fold was seen in about 36% of males and 50% of females. The average height of the double eyelid fold with the eye closed in 20 year old females was 5.2mm and 30 to 50 year old females was 5.5mm. The most frequent shape of the double eyelid fold was type 5. 6. The epicanthus was present in 58.1% in this series and existed in over 90% under age 10, but disappeared in about 90% of the people over 50. The most frequent shape of the epicanthus was tarsalis type.

일반외과 영역에서 염증성 질환에 대한 Claventin^(�)의 임상효과 및 안전성 평가

손기섭,나호청,송인상,이희만,장일성,배진선 최신의학사 1994 最新醫學 Vol.37 No.5

凍結深度 算定에 대한 硏究

민홍기,류제천,김송만,박춘수 忠南大學校 産業技術硏究所 1997 산업기술연구논문집 Vol.12 No.2

Korea has the ground which freezes in winter and melts in warmer seasons by turns. Therefore, in designing civil-structures or buildings on such ground, the depth of seasonal frost penetration must be considered. In this paper, approximate contours of the maximum depth of frost penetration in Korea is presented. The National Construction Research Institute of Korea has measured the depth of the frozen ground covering all the area of South Korea during the ten years ranging through 1980. The measurement were made for the frozen ground at random but intended for the most frost-susceptible soils. The contour of the maximum depth of the frost penetration is drawn on a map with data collected during the ten years. It is known that the maximum depth of the frost penetration is related to freeze index values. An empirical formula expressing the relation is suggested, in which the depth is proportional to the one-fifth power of the air freezing index values.

鮟鱇網 漁具 漁法의 改良에 관한 硏究(Ⅱ) : 展開帆을 이용한 改良漁具 試驗(豫報)

李吉來,宋之浩,朴鍾洙,徐萬錫,趙鳳坤,朴正鎬,洪聖根,鄭公炘,裵錫悌,鄭與基,金鎭乾 군산대학교 1980 群山水産專門大學 硏究報告 Vol.14 No.1

Ordinarily stow net fisheries was used by floater beam and sinker beam for the purpose of spreading the mouth of net. But it was not only iuconvenient and dangerous but much defective. In this thesis, we have studied fundermental experiment of the improved stow net fishing gear using head rope, ground rope and otter sail instead of floater beam and sinker beam. From the result of this experiment, it has been succeeded for fishing work to achieve basically without any difficulty. The results obtained in this study were as follows. 1) The resistance of fishing gear was estimated R≒7V2 as possible as it is taken greatly. (R: Resistance V: the rate of current) 2) The interval of otter sail was spreaded smoothly. Being in normal condition, it was maintamed the width 37-38m. It was heared comparison with net mouth of ordinary gear, and the shearing force was enough. 3) The height of mouth was lower than we have anticipated to and seemed to have the supplement of buoyancy. But according to increasing the rate of current, the lowness of mouth height was little affected. 4) The height of otter sail was decreased at the rate of 30% by the rate of current, on the contrary, the height of wing was not decreased owing to sufficient buoyancy, 5) The adjustment of extention length of hanging wire(connected with fishing boat) and raising wire(with otter sail) was great important problem and it must be dealed with the most moderatly because of a corelation between the spreading of fishing gear and catching ability. 6) On the depth of 30m, it was taken 25 minuits to cast anchor and lines, 20 min cast net, 24 min haul net, 45 min haul lines and heave anchor, respectively. 7) The improved stow net with otter sail was cleared up the defects and difficult problems in ordinary gear using floater beam and sinker beam, and it have more advantages of fishing work than ordinary one. But there were involved in lots of problems in details to solve in the future.

산삼 배양액 급여가 돈육의 이화학적 특성에 미치는 영향

진상근,김일석,송영민,허선진,박기훈,정기종,김동훈,노정만 진주산업대학교 산업과학기술연구소 2006 산업과학기술연구소보 Vol.- No.13

Berkshire를 이용하여 70일간 산삼 배양액 급여 시 육의 이화학적 특성에 미치는 영향은 다음과 같다. 산삼 배양액의 급여에 의해 육의 수분, 조단백, 조지방, 회분, pH, 가열감량, 콜레스테롤 함량, 육색, 조직감의 응집성과 검성, 포화지방산 및 불포화지방산의 비율은 차이를 보이지 않았다. 보수력, 지방색 L^(*)값, 지방산 중 linoleic acid(18:2), arachidonic acid(20:4), 필수지방산의 함량, 아미노산 중 threonine, glutamic acid, valine, isoleucine, leucine, histidine, lysine 및 총아미노산 함량은 산삼 배양액의 급여에 의해 감소하였다. 전단가, 조직감의 표면경도, 경도, 씹힘성, 지방산 중 stearic acid(18:0), oleic acid(18:1) 함량, 아미노산 중 serine, glycine, cystine, methionine, tyrosine 및 phenylalanine의 함량은 산삼 배양액의 급여에 의해 증가하였다. 본 연구결과를 종합하면 산삼 배양액의 급여는 돈육의 경도를 증가시키는 효과 외에 뚜렷한 이화학적인 차이를 나타내지 않았다. 이러한 이유는 급여된 산삼 배양액 내에 함유된 생리활성 물질의 함량이 낮고, 급여수준이 낮은 결과로 사료되어진다. A total of 60 pigs (Berkshire) were used to investigate the effect of dietary artificial culture medium of wild ginsengs (CMG) on physico-chemical characteristics of pork. About 60 kg pigs were randomly alloted into one of two experimental diet groups (C:commercial diet feed; T:commercial diet + 1 L CMG per day for 70days). Pigs were slaughtered at approximately 110 kg live weight, and chemical composition and physico-chemical characteristics were measured in pork loin. Moisture, crude protein, crude fat and ash were not significantly different by dietary artificial culture medium of wild ginsengs. Water-holding capacity was decreased by dietary artificial culture medium of wild ginsengs, while shear force was increased. However, pH, cooking loss and cholesterol contents were not significantly different between two different treatments. In color, L^(*) of fat was decreased by dietary artificial culture medium of wild ginsengs. Brittleness, hardness and chewiness were increased in dietary artificial culture medium of wild ginsengs group. In fatty acid, stearic acid (18:0) and oleic acid (18:1) were higher in dietary artificial culture medium of wild ginsengs group, whereas linoleic acid (18:2) and arachidonic acid (20:4) were higher in control group. In amino acid, serine, glycine, cystine, methionine, tyrosine and phenylalanine were higher in dietary artificial culture medium of wild ginsengs group, whereas threonine, glutamic acid, valine, isoleucine, leucine, histidine and lysine were higher in control group.

인삼이 alcohol 투여백서의 혈액성분에 미치는 영향에 관한 연구

김창세,조만희,송기창,라창수 순천향대학교 1982 논문집 Vol.5 No.2

White rats were given with combined ginseng extract and 40% alcohol(group A) and 40% alcohol(group B), by catheter through Mouth, periode from 1 to 30 th day. Control A and B groups were pretreated wish ginseng entracts for 15 days. The following results were obtained; 1. In red blood cells group A was increased 1 to 30 th day. Group B was increased 1 to 7th day and then decreased 10 to 30th day 2. In serum triglyceride concentration, group A was increased 25∼30 th day but group B. was increased whole period except 3∼7 th day. 3. Decreases of Serum phospholipid and cholestero1 concentrations resulted from pretreament of ginseng extract for 15 days, but interruption or alcohol administration recovered to normallevel immediately. 4. In Serum GOT concentration group B was increased 10 to 30 th day but group A was normal level. 5. In serum protein fractionation albumin and r-globu1in concentrations were increased in both groups. 6. Serum GPT, Thymol turbidity, creatinine, total lipid and alcohol concentrations and liver alcohol dehyrogenase activity were within normal limits in compared to control group.

Silibinin Inhibits Tumor Growth through Downregulation of Extracellular Signal-Regulated Kinase and Akt <i>in Vitro</i> and <i>in Vivo</i> in Human Ovarian Cancer Cells

Cho, Hyun Jin,Suh, Dong Soo,Moon, Soo Hyeon,Song, Yong Jung,Yoon, Man Soo,Park, Do Yoon,Choi, Kyung Un,Kim, Yong Keun,Kim, Ki Hyung American Chemical Society 2013 Journal of agricultural and food chemistry Vol.61 No.17

<P>Anticancer activity of silibinin, a flavonoid, has been demonstrated in various cancer cell types. However, the underlying mechanisms were not elucidated in human ovarian cancer cells. The present study was undertaken to examine the effect of silibinin <I>in vitro</I> and <I>in vivo</I> on tumor growth in human ovarian cancer cells. Silibinin decreased cell viability in a dose- and time-dependent manner. Silibinin caused an increase in reactive oxygen species (ROS) generation, and the silibinin-induced cell death was prevented by the antioxidant <I>N</I>-acetylcysteine (NAC). Western blot analysis showed silibinin-induced downregulation of extracellular signal-regulated kinase (ERK) and Akt. Transfection of constitutively active forms of MEK and Akt prevented the silibinin-induced cell death. Oral administration of silibinin in animals with subcutaneous A2780 cells reduced tumor volume. Subsequent tumor tissue analysis showed that silibinin treatment induced a decrease in Ki-67-positive cells, an increase in transferase-mediated dUTP nick end labeling (TUNEL)-positive cells, activation of caspase-3, and inhibition of p-ERK and p-Akt. These results indicate that silibinin reduces tumor growth through inhibition of ERK and Akt in human ovarian cancer cells. These data suggest that silibinin may serve as a potential therapeutic agent for human ovarian cancers.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/jafcau/2013/jafcau.2013.61.issue-17/jf400192v/production/images/medium/jf-2013-00192v_0008.gif'></P>