개에서 이중 결찰법을 통한 동맥관 개존증의 완치 예

윤헌영,정순욱,박희명,박철,정만복,김준영,한현정,황민,노병국,박상혁,장하영,박정윤 한국임상수의학회 2004 한국임상수의학회지 Vol.21 No.1

A ten months old, female Yorkshire terrier weighing 2.88 kg referred to veterinary teaching hospital of college of veterinary medicine, Konkuk University because of syncope, cough and dyspnea. First hematological and serum chemical test revealed thrombocytopenia, mild anemia, and increase of concentration of ALP (195 U/L). On 57 days later, second hematological and serum chemical test revealed polycythemia, increase of concentration of ALP (211 U/L), and Tchol (387 mg/dl). Right atrium enlargement, main pulmonary artery bulge and cardiomegaly (VHS = 11.5) were observed in radiographic findings. Ultrasonographic images showed both right and left ventricular dilation and turbulent flow between the descending aorta and the main pulmonary artery in color Doppler imaging. ECG showed left ventricular enlargement, SA block, and electrical alternant. Thoracotomy was performed through left fourth intercostal incision under isoflurane anesthesia. Patent ductus arteriosus was double ligated with 1-0 silk. Cough and dyspnea disappeared on 5 days after operation. Turbulent flow was not found in color doppler imaging of ultrasonography on 10 days after operation. Ten months later after the operation, syncope could not exist any more.

多環芳香族炭化水素類에 의한 화학발암의 양자생화학적 해석

朴柄珏,都聖鐸,徐萬哲 嶺南大學校附設 基礎科學硏究所 1986 基礎科學硏究 Vol.6 No.-

The interaction of polycyclic aromatic hydrocarbons (PAH) with deoxyrkbonucleic acid(DNA) were studied by means of extended Huckel method. Assuming that the formation of a loose molecular complex between each PAH and DNA is the first step of chemical carcinogenesis, the plausible orientation of the complex formed between the PAH and the the adenine-thymine pair or the guanine-cytosine was figured out. On the basis of the most probable orientation, the charge transfer quantities of the DNA bases (A-T pair and G-C pair) and PAH complexes were calculated and compared with carcinogenicity. It was found that the parallel relationship between charge transfer quantity of the G-C pair and PAH complex and carcinogenicity exists, but not between that of the A-T pair and PAH complex and carcinogenicity. Thus, the interaction of the G-C pair with the carcinogens seems to play an important role in the carcinogenesis.

유동층 생물반응기의 구조변화에 따른 하수처리

박종만,이재용,김철경,고창웅,김남기 대한상하수도학회 2004 상하수도학회지 Vol.18 No.2

The purpose of this study is to investigate the biofilm reactors capable of doing high efficiency treatment. Vertical fluidized bed biofilm reactor(VFBBR) and spiral fluidized bed biofilm reactor(SFBBR) was used for their performence in biodegradation of artificial sewage. The factors influencing the efficiency of those reactors were compared with difference of physical condition. They had same size but different structure to gain access of its unique characteristics. When recycle solution with flow rate of 22 mL/min and artificial sewage with flow rate of 2-10 mL/min were fed into two reactors in aerobic state, the average COD, removal rate for biodegradation of SFBBR was greater than VFBBR. After reactor feed sewage was constantly maintained as flow rate of 4 rnL/min and the recycle solution were changed to 10-32 mL/min respectively, the average COD,, removal rate of artificial sewage in SFBBR was greater than VFBBR. In this experiment for addition of support media into two reactors SFBBR was 4.1% excellent than VFBBR. Above all, SFBBR excelled VWBR in boidegradation of organic matter in sewage.

황, 산소 및 질소 헤테르 고리화합물의 방향족 치환반응성에 관한 분자궤도론적 해석

朴柄珏,金鎬順,徐萬哲 嶺南大學校附設 基礎科學硏究所 1986 基礎科學硏究 Vol.6 No.-

The electrophilic substitution reascivities were invesitigated for sulphur-, oxygen-, and nitrogen-containing aromatic compounds by simple Huckel MO method, separatively. It was found that electrilic reactivity index, S??, for sulphur-containing aromatic compound was related in parallel with the experimental partial rate factor contant, σ+. The reactivities of each position are predicted for the same type of hetero compounds in which N or O atom is substituted for S atom on the basis of observed good parallelism between the S?? and the σ+ for the sulphur-containing aromatic compounds.

韓.日 하이테크産業의 硏究開發과 마아케팅 統合에 관한 實證的 硏究

朴仁守,朴徹敏,黃華鐵,金容萬 慶南大學校 産業經營硏究所 1994 産業經營 Vol.17 No.-

분자역학적 방법을 이용한 부산시내 대형건물 냉각탑수의 레지오넬라균의 형별 분류

김정만,정석훈,서대영,박은희,송은주,최재철,이은엽,장철훈 대한임상미샐물학회 2004 Annals of clinical microbiology Vol.7 No.1

龜尾市 人文系高等學生들의 吸煙實態와 關聯要因 分析

南喆鉉,朴千萬,崔銀庭 慶山大學校 保健福祉硏究所 1999 保健福祉硏究 Vol.3 No.-

고등학생들의 흡연실태와 이에 영향을 주는 요인을 파악하여 건전한 청소년 시절을 보낼 수 있도록 하는 금연 교육 프로그램 개발에 필요한 기초자료를 제공하고자 1998년 2월 28일부터 3월 7일까지 경북 구미시 소재 고등학생 6개 인문계 고등학생을 대상으로 설문조사 한 바 다음과 같은 요약과 결론을 얻었다. 1) 조사대상자의 일반특성은 여자가 50.5%였고 학년별로는 1학년이 34.0%로 가장 높았으며 2학년 33.7%, 3학년 32.3%였다. 종교는 무교가 47.5%로, 한달용돈 3만원 이하에서 43.4%로, 고졸자 아버지를 둔 학생이 47.1%였고 흡연하는 부모와 생활하는 학생이 66.3%로 높았으며, 스트레스가 심하다는 학생이 75.1%, 술을 마시는 학생이 79.5%로 타군보다 높았다. 2) 특성별 흡연실태 (1) 고등학생의 흡연률은 24.9%였으며 남학생 흡연률은 25.2%였고 여학생은 24.7%였다. 학년별 흡연률은 1학년에서 28.7%, 3학년 28.1%, 2학년 18.0% 순이였다. 특성별로는 불교신자에서 22.2%로, 한달용돈 3-5만원에서 35.5%로, 가정에서 부모가 흡연을 하는 경우 26.4%로 타군에 비해 각각 높았다. 학교성적이 나쁜쪽이, 스트레스가 심할수록 술을 마실수록 흡연률이 높았다. <표5> 변수별 상관관계 ------------------------------------------------------------------------------------------------------------------- 구분 1 2 3 4 5 6 7 8 9 10 11 12 -------------------------------------------------------------------------------------------------------------------- 1. 성별 1.0000 2. 학년 0.0209 1.0000 3. 종교 0.0405 0.0831 1.0000 4. 용돈 0.0230 0.0783 -0.0354 1.0000 5. 아버지교육정도-0.0772 -0.0279 0.0870 -0.0058 1.0000 6. 학교성적 0.0578 0.0789 -0.0206 0.0008 -0.0694 1.0000 7. 부모님맞벌이 -0.1119** -0.0278 0.0714 -0.0249 0.2207* -0.0246 1.0000 8. 부모님흡연여부 -0.0070 0.0640 0.0040 0.0138 0.0103 0.0043 -0.0733 1.0000 9. 스트레스 정도 0.0052 -0.0783 -0.0014 -0.1287** -0.0400 0.0943 0.0078 0.0015 1.0000 10. 음주여부 0.0365 -0.1328** 0.0470 -0.1990* -0.0089 -0.0118 -0.1042 0.0624 0.0923 1.0000 11. 가정화목 0.1206** 0.0339 -0.0299 0.1028 -0.0973 0.0756 -0.1461** 0.0987 -0.0339 -0.1014 1.0000 12. 흡연여부 0.0058 0.0072 -0.0456 -0.1455** -0.0752 -0.1208** -0.0605 -0.0480 0.1580** 0.2929** -0.1181** 1.0000 ------------------------------------------------------------------------------------------------------------------------ * : P<0.01 ** : P<0.05 (2) 흡연량은 1일 1-10개피가 52.7%였고, 1갑이상이 27.0%, 11개피에서 한갑을 피우는 경우가 20.3% 였다. 특성별로는 1일 1-10개피는 여자에서 62.2%로, 1일 한갑이상에서는 남자가 29.7%로 높았다. 학년별로는 전학년 모두 1-10개피가 가장 높았고, 용돈이 3만원 이하에서 1일 한갑이상이 36.1%로 가장 높게 나타났다. 학교성적 하위군에서는 1-10개피가 53.9%, 한갑이상이 38.5%로 타군에 비해 높았다. 흡연을 하는 부모를 둔 학생에서 30.8%가 1일 한갑 이상 흡연을 하였고 스트레스가 심하지 않을 때는 흡연을 하지 않았다. (3) 흡연 시작시기는 중학교 재학중이 52.7%로 가장 높았고, 중학교 졸업 후가 27.0%, 중학교 입학전이 20.3%였다. 흡연 시작시기를 각 특성별로 보면 중학교 재학중이 여자에서 62.2%, 1학년에서 72.4%, 한달용돈 5만원 이상에서 66.7%, 학교성적이 상위에서 69.2%, 스트레스가 심한 학생에서 57.8%로 각각 타군 보다 월등히 높았다. 맞벌이 부모와 흡연을 하는 부모를 둔 학생에서 중학교 입학전에 각각 22.6%, 22.7%로 흡연을 시작하여 타군에 비해 다소 높았다. (4) 흡연장소는 놀이터, 공터가 33.8%로 가장 높았고 자기집 17.6%, 비디오방이나 노래방이 17.6%로 같은 순이였다. 특성별로는 놀이터, 공터에서 흡연이 남자에서, 3학년에서, 무교에서, 한달용돈 3-5만원에서, 학교성적이 상위수준에서, 스트레스가 보통에서 각각 타군보다 높았다. 부모가 흡연을 하지 않는 학생들은 자기집에서 흡연이 적었고 놀이터나 공터에서 흡연이 많았다. (5) 흡연동기는 호기심이 39.2%로 가장 높았고 스트레스 해소가 23.3%였다. 특성별로 보면 호기심으로 흡연을 한 경우가 여자에서, 2학년에서, 기독교에서, 초대졸 이상의 아버지를 둔 학생에서, 학교성적이 중간인 학생에서, 맞벌이 부모를 둔 학생에서, 비흡연 부모를 둔 학생에서, 스트레스가 심한 학생에서 각각 타군보다 높았다. (6) 담배를 가장 피우고 싶을 때는 언제 느끼느냐는 흡연유혹에 대한 문항에서 친구의 흡연이 35.1%로, 심리적 갈등이 33.8%로 높았다. 친구의 흡연에 유혹을 받는 경우는 여자에서 48.7%로, 1학년이 51.7%로 타군보다 높았다. 3) 특성별 흡연 관련요인 (1) 금연의지 유무에 있어서는 금연을 하겠다가 81.1%였고, 금연을 안하겠다는 18.9%였다. 성별로 보면 금연을 하겠다는 남자가 86.5%, 여자는 75.7%로 나타났다. 특성별 금연의지는 3학년에서 88.9%, 불교신자에서 93.8%, 한달용돈 5만원에서 91.7%, 학교성적이 하위수준에서 87.0%로 각각 타군보다 높았다. (2) 장래 흡연여부는 안피운다가 79.4%로 가장 높았고, 사회인이 되어서가 4.9%, 대학생일때가 4.5%였다. 성별로 보면 안피운다가 여자에서 85.0%로 가장 높았고, 특성별로 안피운다가 1학년에서 81.9%, 기독교 신자에서 78.6%, 한달 용돈 3-5만원에서 85.9%, 중졸이하의 아버지를 둔 학생에서 83.6%로 각각 타군에 비해 높았다. 흡연을 하지 않는 부모를 둔 학생의 83.3%가 안피우겠다고 응답하였고 스트레스가 심하지 않은 경우는 100%로 절대적으로 높았다. (3) 흡연으로 인한 질병에 대한 지식 조사에서는 폐암이라고 응답한 자가 92.6%로 가장 높았다. 특성별로 보면 폐암이라고 응답한 경우는 남자에서, 2학년에서, 기독교 신자에서, 학교성적이 상위수준에서, 부모가 흡연을 하는 학생에서, 스트레스가 심하지 않은 군에서, 술을 마시는 학생에서 각각 타군 보다 월등히 높았다. (4) 흡연의 건강장해에 대한 정보 습득원은 신문, 잡지가 56.0%로 가장 높았고 학교가 21.8%, T·V나 라디오가 15.5% 순이였다. 특성별로 보면 신문, 잡지가 정보 습득원인 경우는 여자에서, 1학년에서, 기독교 신자에서, 한달용돈이 3-5만원에서, 중졸이하의 아버지를 둔 학생에서, 맞벌이를 하지않는 부모를 둔 학생에서, 담배를 피우지 않는 부모를 둔 학생에서 타군보다 높았다. 학교성적이 상수준에서 학교가 29.2%로 정보 습득원이였으며, P<0.05 수준으로 유의성이 있었다. 4) 성별 흡연실태 (1) 여성흡연에 대한 견해를 질문한 결과 남학생의 경우 「남성과 달리 절대 피워서는 안된다」가 41.5%로 가장 높으며 「남성과 동등하게 피워도 된다」는 23.8%로 였다. 여학생의 경우에는 「잘 모르겠다」가 26.7%로 가장 높고, 「남성과 달리 절대 피워서는 안된다」가 22.7%인 반면 「남성과 동등하게 피워도 된다」는 견해가 20.7%로 나타났다. (2) 담배 구입시 태도에 관한 질문에 구입시 「죄책감을 느낀다」라고 응답한 남학생이 18.9%, 여학생이 13.5%인 반면에 「그냥 그렇다」라고 응답한 남학생이 48.8%, 여학생이 67.6%로 훨씬 높았다. (3) 흡연시 동반자는 여자친구가 32.4%, 남자친구가 28.4%로 친구와 함께가 가장 많았으며, 혼자서가 23.0%이고, 선후배와 함께가 16.3%였다. 5) 성별과 가정화목은 정상관 관계가 있고, 학년과 음주여부 그리고 부모님 맞벌이와 가정화목은 역상관 관계를 보였다. 스트레스 정도와 음주여부는 흡연여부와 정상관 관계가 있고, 한달용돈, 학교성적, 가정화목은 흡연여부와 역상관 관계가 있었다. The following results were obtained from my questionaire that purports to provide basic materials for an educational program 'Quit Smoking' for high school students. The program, if succeeded, would provide an opportunity for students to spend a productive and sound adolescence. The questionaire was circulated and collected among 300 students attending at various high schools in the City of Kumi, Kyungbuk, during March 28th through April 7th of 1998. 1. The characteristics of the students who answered the questionaire are: 50.5% of them are female students; 34.0% freshmen, 33.7% sophomores, and 33.2% seniors; atheists are 47.5%; 43.4% consist of those who have monthly allowance of less than ￦30,000; 47.1% have fathers who are only highschool graduates; 66.3% have parents who are smoking; 75.1% feel stress at school; and 79.5% drink alcohol occasionally. 2. Total smoking percentage among the answerers is 24.9%. Smoking rate for male students is 25.2% while smoking rate for female students is 24.7% and seems increasing. The smoking rate of students whose parents are smoking is higher than that of other groups. And those students group with stressful life, bad grade at school, and drinking habit, has the highest rate of smoking. 3. Among the smokers, 52.7% consume 1-10 cigarettes a day. 27% of them consume more than a pack a day, 20.3% smoke away more than half a pack but less than a pack. And 62% of female smokers are consuming only 1-10 cigarettes whereas 29.7% of male students consume more than one pack a day. 4. 52.7% of smoking students started smoking while they were at middle school, 27.0% started after graduation from middle school, and 20.3% started even before middle school. 5. They choose as their favorite smoking place playground or empty lot with 33.8% of them, and home 17.6%, video-room('videobang') 17.6%, and singing-room('noraebang) 17.6% respectfully. 6. 39.2% of all amokers answered that curiosity is the highest motive to have started smoking, and 23.3% said that they started smoking in order to release their stress. 7. Smoking impulse is most felt when friends are smoking, with the highest rate of 35.1% of all smokers, while 33.8% of them felt a seduction to smoke due to psychological stress. Among those who are easily seduced to smoke because of friend's smoking are 48.7% of all female smokers and 51.7% of all freshmen smokers. 8. 81.1% of smoking students have positive attitude to quit smoking, but 18.9% has no intention to quit. Among the students who answer 'yes' to quit smoking 86.5% are male and 75.7% are female. 9. About future smoking attitude, 79.4% of all questionaire answerers predict that they will not smoke no matter what; 4.5% will when they become college students; and 4.9% will only when they become members of society. 10. With the highest 92.6% rate, many smokers answered that smoking may cause lung cancer. 11. 56% of all smoking students have obtained their knowledge of smoking diseases from newspapers and magazines, 21.8% from school education, and 15.5% from T.V. or radio. 12. About female smoking, 41.5% of male students answered that women should not smoke while 23.8% of them seemed to admit that there should be no difference between sex roles in smoking. Female students replied 'no opinion' with the rate of 26.7% while 20.7% of them insist equality of men and women in smoking. 13. 18.9% of male smokers and 13.5% of female smokers 'feel guilty' when they purchase cigarettes, but 48.8% of male and 67.6% of female smokers 'feel nothing' at purchase. 14. Smoking mate consists of girl friends (32.4%) and boy friends (28.4%). But 23.0% of smokers are simply smoking alone without mates, and 16.3% of them are smoking habitually with their high school seniors or juniors. 15. Stress and alcoholic consumption are causes in a direct proportion to smoking increase, whereas monthly allowance, school grade, and domestic peace induce factors in an inverse proportion to smoking rate.

백서에서 신 허혈성 손상에 미치는 칼슘 길항제의 효과

문철웅,정종훈,박천국,이승일,배학연,장경식,김만우,정춘해,홍순표,이병래,김호중 朝鮮大學校 附設 醫學硏究所 1993 The Medical Journal of Chosun University Vol.18 No.1

Renal ischemia is one of the most common causes of acute renal failure. Four factors related to the pathogenesis of acute renal failure are vasoconstriction, decreased glomerular filtration rate, tubular back leak of filtrate, and intratubular obstruction. The cellular response to renal ischemic insults include decreased content of adenosine trihosphate, lipid peroxidation induced membrane degradation, alteration in cellular pH, and calcium or phospholipase induced mitochondrial dysfunction. Much attention has been given to the role of increased cellular calcium as a pathogenetic contributor to cell injury during ischemia. Author studied the protective effects of calcium antagonists on cellular injury during renal ischemia in rat. To investigate the protective role of these agents, author measured the amount of malondialdehyde(MDA) and the enzyme activities of free radical scarvengers-superoxide dismutase(SOD), catalase and glutathione peroxidase from non-pretreated group and calcium antagonists pretreated groups in control, ischemia and reflow subgroups. The results were summerized as follows: 1) The amount of MDA in non-pretreated group was higher in the reflow compared with the control(<p<0.01). But, in all pretreated groups, there was no statistically difference in the amount of MDA. 2) The SOD activity in non-pretreated group was lower in both the ischemia and the reflow compared with the control (P<0.05). But, in both verapamil and trifluoperazine-pretreated groups, there was no statistically difference in the SOD activity. 3) Both catalase and glutathione peroxidase activities in non-pretreated group were lower in both the ischemia and the reflow compared with the control (P<0.05). But in all pretreated groups, there was no statically difference in both catalase and glutathione peroxidase activities. These results suggest that free radical mediated ischemic injury by renal artery clamp in rat can be protected by intraperitoneal pretreatment with calcium antagonists. As trifluoperazine has a protective effect in renal ischemia, the calcium activated calmodulin dependent enzyme may play a role in renal ischemic injury.

저에너지 사료 급여가 거세 비육돈의 성장과 도체 품질에 미치는 영향

이철영,이희포,이진희,박만종 진주산업대학교 농업기술연구소 2000 農業技術硏究所報 Vol.13 No.-

Barrows eat excessively more feed than gilts and as a result, their carcass grades are, in general, lower than those of the latter. The present study was conducted to investigate the effect of a low-energy diet on growth and carcass quality in finishing barrows and thereby to draw a guideline for the usage of it. In experiment I(Exp. I), 60 LYYD cross-bred barrows weighing ~70kg were randomly assigned into four pens and fed ad libitum either of two finishing diets containing 103%(control diet) and 87%(low-energy diet) of the NRC digestible energy(DE) requirements, respectively, up to slaughter at ~105kg. Exp. Ⅱ was same as Exp. Ⅰ except that average initial weight of the barrows(48 heads) was ~60kg and feed intake was measured. In Exp. I, by feeding the low-energy diet, average daily gain(ADG) was decreased(P<0.05); backfat thickness corrected for 110kg of live weight tended to be decreased(P=0.11); and the ratio of A,B grade carcass was not apparently affected[93%(low-energy diet) vs 90%(control)]. In Exp. II, as in Exp. I, ADG was decreased by feeding the low-energy diet vs control, which is interpreted to have resulted primarily from a 14% decrease in total DE intake. Compared with control, low-energy diet group had a similar average daily feed intake(3.10 vs 3.04kg) and a 14% higher feed/gain. In somewhat contrast to the result of Exp. I, backfat thickness corrected for the live weight was not different between the two groups in Exp. II, which is presumed to have resulted mainly from a genetic ununiformity of the animals with respect to this trait. The A,B carcass ratio, on the other hand, was not appreciably different between the two groups(73 vs 83%). In summary, under the current domestic carcass grading system allowing a relatively wide range of backfat thickness for A and B grades, a low-energy diet is considered to be useful only for a barrow population where the A, B carcass ratio is too low for excessive fackfat. More studies are needed, however, to determine whether a low-energy diet will be useful under the situation of international pork market demanding a higher lean meat ratio.

Mirizzi 증후군의 변형된 분류와 치료

김형철,강길호,채만규,김성용,백무준,이문수,박상흠,이문호,김창호,송옥평,조무식,박희주 순천향의학연구소;Soonchunhyang Medical Research Institute 2000 Journal of Soonchunhyang Medical Science Vol.6 No.1

Purpose : The Mirizzi syndrome is relatively rare and preoperative diagnosis of this disease is difficult. In 1978, Morelli suggested the subclassification of the Mirizzi syndrome into acute or chronic form. We experienced 5 cases of acute form. We analysed clinical features, preoperative radiologic findings and operative findings of 18 cases including acute forms which were diagnosed as Mirizzi syndrome and should suggest the modified classification of Mirizzi syndrome for choice of appropriate treatment. Method : From January 1995 to December 1998, 18 cases, of which 8 cases were diagnosed at Soonchunhyang University Chunan Hospital, and 10 cases were reported in the Korean Journal were retrospectively analysed with regard to clinical features, preoperative radiologic findings and operative findings. According to the clinical features, whole cases were divided into type Ⅰ(acute form) and type Ⅱ(chronic form) and then each type of cases were subclassified according to preoperative radiologic findings and operative findings. Results : Of 18 cases there were 5 cases in type Ⅰ(27.8%), 13 cases in type Ⅱ(72.2%). Type Ⅱb was most common. Type Ⅰa cases were treated only with cholecystectomy. We applied cholecystectomy, T-tube choledochostomy and patch technique in type Ⅰb and thpe Ⅰc cases. Cholectystectomies including removal of gallstones and internal drainage procedures were done in type Ⅱ chronic forms. Conclusion : The acute form(Type Ⅰ) of Mirizzi syndrome was suggested by Morelli might be subclassified into typeⅠa,Ⅰb and Ⅰc following the presence of the necrotic defect in common hepatic duct. Through the modified classification of Mirizzi syndrome based on clinical feature, preoperative radiologic findings and operative findings, we can choice appropriate treatment.