영산강 유지유량 확보에 따른 수질개선 효과

김석규,차규석 호남대학교산업기술연구소 2011 산업기술연구논문집 Vol.17 No.2

현재 전국에서 가장 수질이 좋지 못한 영산강을 대상으로 수질개선을 위한 다양한 방법을 검토하고 하천유지용수 확보에 따른 수질개선 효과를 검증하였다. 영산강 하천유지용수 확보를 위해 저수지 증고, 하상여과, 천변저류지 조성, 소규모 댐 건설 등의 방법을 선정하였다. 선정된 방법을 통해 확보된 유지유량에 따른 수질개선 효과를 예측하기 위해 수질모델(QUALKO)을 이용하여 수질의 변화상태를 모의하였다. 그 결과, 하천유지유량 증대가 BOD 3.6mg/L에서 2.5mg/L로 수질개선 효과가 있는 것으로 분석되었다. 주요어: 유지유량, 수질모델, QUALKO A approach based on the water quality model, was presented in this paper, in order to estimate effect of water quality management in Yeongsan River. Effect of water quality study by the increasing instream flow. Method of increasing instream flow was selected construction of washland and small dam, riverbed filtration, reservoir expansion. The results indicated that the instream flow would be effective in water quality improvement. It was suggested that the presented approach could be an useful tool to estimate effect of a water quality management policy. Key words: Instream Flow, Water Quality Model, QUALKO

다형홍반, 스티븐스-존슨 증후군, 독성 표피 괴사 융해증의 임상 및 조직 소견에 대한 후향적 연구 : A retrospective clinico-histopathologic study

차승훈,정상원,박석돈 圓光大學校 醫科學硏究所 1999 圓光醫科學 Vol.15 No.1

Background: Erythema multiforme (EM) is an acute self-limited disease with distinctive skin lesion. Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) has been regarded as variants of EM within continuous spectrum. The reports that EM with mucous membrane involvement and SJS are clinically different disorders prompt us to investigate the relationship between clinical features and causative factors of these dermatoses. Methods: A retrospective clinico-histopathologic study was performed in 59 patients from 1988 to 1996. Results: While most of EM patients showed typical target, raised atypical target, or flat atypical target, purpura with or without blistering was noted in 80% of SJS patients and all of TEN patients. In EM patients, the skin eruption was mainly located acrally or centrally, diffuse involvement was observed in all of TEN patient. The involved skin surface area was wider in SJS and TEN than EM. Through the review of histopathologic slides, we found that 74% (17/23) was inflammatory type which was diagnosed as EM in 76% patients. Drug was the most common causative factor (41%), and there were the clinical evidences of recurrent herpes simplex virus infection in 12% (7/59) patients. Conclusion: We conclude that there is no difference in clinical features of EM, SJS, and TEN compared with reported studies. A detailed and precise prospective study is necessary to elucidate the clinical features and etiology of these unique dermatoses.

Oxalate와 Enrofloxacin투여한 랫트신장에 대한 병리조직학적관찰

오원석,이차수,오규실,정원일,정재용,정다히,정규식 한국임상수의학회 2003 한국임상수의학회지 Vol.20 No.4

To investigate the renal effects of enrofloxacin administration on rats induced with dehydration or hyperoxaluria, male rats were treated with enrofloxacin of 50 mg to 500 mg/kg b.w.. The microscopical observations of kidney and urine sediment were carried out in the experimental groups. The result obtained were as follows; The male rats deprived of water for 72 hours and administered with enrofloxacin. As enrofloxacin administration dose was increased, clinical signs such as loss of appetite, depression, weakness, and loss of urine output became more severe. In the histopathological findings, there were hyperemia and hemorrhage in renal cortex, vacuolation and necrosis of renal tubular epithelia, proteinous casts within renal tubules. The male rats were orally administered with sodium oxalate and injected with enrofloxacin for 7days. As enrofloxacin administration dose was increased, clinical signs such as the loss of appetite and water consumption, and weakness became more severe. In the histopathological findings, there are hemorrhage of glomeruli and cortical hyperemia, vacuolation and necrosis of tubular epithelia, proteinous casts in renal tubules. In the microscopical findings of urine sediment, there are calcium oxalate crystal (diamond-like type) and magnesium ammonium phosphate crystals (rhomboid). The male rats were intraperitoneally injected with sodium oxalate and administered with enrofloxacin for 7days. As enrofloxacin administration dose was increased, clinical signs such as the loss of appetite and water consumption, weakness were more severe. In the histopathological findings, there were hyperemia and hemorrhage in both glomeruli and renal cortex. Severe necrosis of renal tubular epithelia, bluish materials within renal tubules were also found. In the microscopical findings of urine sediment, there were many calcium oxalate crystals. The present results suggest that enrofloxacin has some injurious effects in rats having dehydration or hyperoxaluria, and clinically, we should consider these renal injury effects when we use enrofloxacin in patients accompanied renal disease, dehydration and hyperoxaluria conditions.

Dysfunction Syndrome을 가진 만성 요통환자의 요천골도수교정에 의한 자세의 변화 : 증례 보고 2

전차선,유경석,김택연 대한정형물리치료학회 2003 대한정형도수물리치료학회지 Vol.9 No.2

본 case study는 척추 관절에 변화를 일으켜 근육의 변화와 통증에 변화가 있는 지를 알아보기 위하여 dysfunction syndrome을 가진 5명의 만성 여성 요통환자의 single group에 Geenman의 impulse technique(glade5)을 1회 적용 후 Pain Scale와 IBS -2000를 사용하여 검사 하였다. - Pain Scale는 0 ~ 100 단계로 나누어 환자에게 직접 아픈 정도를 기입하게 하고 치료 후 재검사와 통증의 변화 정도를 기입하게 하였다. -lBS-2000는 체형 진단기로써 레이저를 이용하여 인체 근육의 경사도를 등고선으로 나타내는 측정기로서 주로 근 Balance와 체형의 균형을 알아보는 기구이다. 측정 방법은 후두-견봉의 각도, C7-견봉의 각도, L4 -S2의 각도, 전 후만의 비, 척추의 기울기를 측정하였다. 자료 분석은 Pained T - test을 하였다. 이 측정치의 결과로 Dysfunction syndrome을 가진 요통환자의 척추 및 근 평형성의 다음과 같은 결과를 얻었다. 1. 주관적인 통증 변화는 교정 전 407.07 였고, 교정 후 309.24로 p<0.05를 보여 유의한 차이가 있었다. 2. 객관적인 측정으로써 후두 -견봉의 각도 변화는 교정 전 왼쪽 362.60, 오른쪽 373.16 였다. 교정 후 왼쪽 33.704.31, 오른쪽 353.05로 p>0.05를 보여 각도의 변화는 보이나 유의한 차이를 보이지 못 하였다. 3. C7 -견봉 각도의 변화는 교정 전 왼쪽 173.73, 오른쪽 175.30 였다. 교정 후 왼쪽 162.55, 오른쪽 172.07로 p>0.05를 보여 각도의 변화는 보이나 유의한 차이를 보이지 못 하였다. 4. 요추 골반의 각도 변화는 왼쪽 19.58 2.75, 오른쪽 20.13 2.75 였다. 교정 후 왼쪽 19.793.33, 오른쪽 21.094.51로 p >0.05를 보여 각도의 변화는 보이나 유의한 차이를 보이지 못하였다. 5. 척추의 전·후만 깊이의 변화는 교정 전 TTD는 2.20 1.44cm , TLD는 2.070.53cm 였고 교정 후 TTD는 2.19 0.49cm , TLD는 1.880.11cm 로 수치의 변화를 보이나 p>0.05로 유의한 차이는 없었다. 6. 척추의 전·후만 비의 변화는 교정 전 TTDR은 0.560.20, TTDR은 0.430.02 였고 교정 후 TTDR은 0.630.02, TLDR은 0.350.02로 변화를 보이나 유의한 차이는 없었다. 7. 척추의 기울기의 변화는 교정전 XD/YD는1.720.77, 교정 후 0.900.41로 수치의 변화는 보이나 유의한 차이를 보이지 못하였다. 전체적인 평형성의 수치를 보이나 유의한 차이는 보이지 못 하였다.

Orotic acid 투여가 흰쥐의 혈청, 肝臟 및 腎臟 지질 농도에 미치는 영향

김석환,車載英,조영수 東亞大學校附設遺傳工學硏究所 1997 遺傳工學硏究 Vol.- No.4

Orotic acid 의 과잉 섭취는 지질대사의 이상으로 인한 간 장해를 야기시키는 것이 알려져있다. 특히 지방간 생성에 대하여 관심을 가지게 되어서 본 연구는 orotic acid에 의한 혈청, 腎臟및 肝臟의4 지질 농도에 미치는 영향에 대하여 검토하였다. 시판 분말 chow 식이에 orpotic acid 1% 첨가, 무첨가한 식이를 21일간 90g전후의 성장기 Spragud-Dawley 系 웅성 쥐에 급여하였다. 그 결과 orotic acid 1% 첨가 식이에서 혈청 cholesterol, triglyceride및 phospholipid 농도는 각각 5% 수준에서 유의하게 저하하였다. 肝臟의 triglyceride농도는 5% 수준에서 유의하게 저하하였다, Orotic acid 첨가 식이에서 肝臟중량은 증가한 반면 腎臟중량은 저하하였다. Orotic acid 1% 첨가한 군에서 肝臟및 腎臟의 phospholipid 조성에의 영향은 인정되지 않았으나, 腎臟의 lysophosphatidylcholine은 높은 증가율을 보였다. 肝臟 phospholipid와 비교하여 腎臟에서는 sphingomyeline phospphatidylethanolamin은 유의하게 높은 분포를 나타냈다. 腎臟 phospholipid의 지방산 조성중에서 linoleic acid(18:2)가 상승하고 arachidonic acid (20:4)가 감소하였다. It was generally known that over-ingestion of dietary orotic acid caused hepatic disorder by the lesion of fatty acid and cholesterol synthesis in rats. The present study was carried out to investigate the effects of dietary orotic acid on the lipid composition of serum. liver and kidney of rats. For the experiments rats were fed with commercialized chow powder diet in the presence or absence of 1% orotic acid. The prepared diets were fed to male rats (Sprague-Dawley strain. 90∼100g of body weight) for 21 days. According to the results, orotic acid treated group showed that each concentration of serum cholesterol, triglyceride and phospholipid was significantly decreased (p<0.05). The centration of liver triglyceride was significantly decreased (p<0.05). In the presence of 1% orotic acid, the weight of liver increased while that kidney decreased. The treatment of orotic acid seemed to have no effects on the phospholipid composition in liver and kidney, except the kidney lysophosphatidylcholine. In the comparison of the phospholipid composition between liver and kidney, the levels of sphingomyeline and phosphtidylethanolamine in the kidney were higher than those in the liver. Among the composition of fatty acid in kidney, the concentration of linoleic acid (18:2) was increased, and the concentration of arachidonic acid(20:4) was decreased with the addition of the orotic acid.

Louis I. Kahn의 디자인 개념과 형태 요소에 따른 평면구성 SCHEMA에 관한 연구

송석현,차명열,김원갑 대한건축학회 2004 대한건축학회논문집 Vol.20 No.3

Design is a result from representation of visual language by designer's creative thinking and reasoning, and operated only in our internal organization system. Design as ill-defined problem cannot be described logically and perfectly. Depend on situation, design require subjective analysis. and It has the organization of What is Rank character. But because "Concept" is only considered in the designer's thinking system, shape vocabularies that actually can be used for expressions of design are extremely restricted. Sometimes design should start with changing situations, unclear requirements, subjective analysis. But design concept can control design thinking system from starts to productions. Design concepts are stored in our brains and retrieved as three major types such as elements, relationships and schema. One of these words, the schema that formed by problems settlement and process repetitions for the best conclusion, not only play an important part in the designer's thinking system about a specific problem but also appeared by distinctive features and included by connotations as like a designer's ideology. At this point. The purpose of this study is that analyze not only the formative expression but also modeling process of design elements in modern architectural design to establish a clear-system of "Design Operating System" and to show the "Characteristic of Plane Organization" by the he Architectural Design Elements and the Relationship through the Design of Louis I. Kahn. and Design knowledge as elements, relationships and schema have been explained to understand "Design System" operated in our brains. Upon these studies, design of Louis, I. Kahn have been analysed.

손가락에 발생한 피하 석회화 결절 1예

이원채,차영창,이석종,나건연,김도원,이수경 대한피부과학회 2003 대한피부과학회지 Vol.41 No.10

Subepidermal calcified nodule is a rather uncommon, but peculiar subtype of calcinosis cutis. It presents as a single asymptomatic, hard, yellowish white nodule which commonly occurs on the face of chileren. Histopathologic examination reveals the multifocal various-sized papillary dermal collection of dark blue amorphous globular deposits confirmed by von Kossa stain for calcium. We report a 42-year-old man who had small white hyperkeratotic papule on finger tip for more than 20 years. He could recall neither preceding trauma nor systemic illness. Excisional biopsy, with the clinical impression of verruca or corn, showed typical histopathologic features of the subepidermal calcified nodule.(Korean J Dermatol 2003;41(10) : 1414~1416)

Comet Assay 를 이용한 제주 자생 녹조류 추출물의 세포내 DNA 손상 억제 활성 효과

안긴내,이승홍,차선희,고석천,전유진 제주대학교 방사능이용연구소 2006 방사선응용과학연구소논문집 Vol.20 No.-

학습부진아의 수 개념 학습을 위한 멀티미디어 단계별 코스웨어 설계 및 구현

김현배,최차석 부산교육대학교 과학교육연구소 2000 科學敎育硏究 Vol.25 No.-

CAI(Computer Aided Instruction) can make possible the learners feel the interest, motivation and individual teaching. It is especially useful to the learners feeling a difficulty and fear in communication. Most of all, in the recent part of computer many developments of internet and multimedia technology have provided the learners various educational materials such as sound, letter, picture, animation and moving screen and so on. These materials give rise to learners interest and motivation in learning and can make the underachievers concentrate their attention on learning. In this study the author has researched and analyzed the underachievers' learning trait, set up the learning model effectively learning the numeric concept, projected the multimedia courseware based on this.

신경회로망을 이용한 한글모음인식에 관한 연구

최승호,김자룡,이기영,최갑석 明知大學校 産業技術硏究所 1989 産業技術硏究所論文集 Vol.8 No.-

In this paper, Recognition of HANGUL Vowel using a neural network is studied. In general, Back-propagation is applied for the speech recognition, but has too much computational time for learning. The method using peak information of speech signal is used for the purpose of reduction of computational time. The speech spectrum of a vowel consists of the sixteen frame and a frame is divided by the sixteen hand and binary code 1,0 is used as input data corresponding to whether peaks exist or not, respectively, on each band in frequency spectrum. The experimental result show that the learning number is reduced remarkably and the recognition rate is improved according to increasing ratio of learning and unlearning data.