하악측두관절에서 퇴행성 관절염의 실험모델 개발

신상훈,송동석,김철훈,황대석,김용덕,김욱규 부산대학교 병원 암연구소 2007 부산대병원학술지 Vol.- No.21

Purpose : The purpose of this study is to investigate temporomandibular joint arthritis that was induced by intra-articular injection of collagenase in rabbits. Material and Methods: In this study, 12 rabbis was used. We injected collagenase on temporomandibular joint of rabbit and observed for six weeks. H-E stain was done. Results : Four weeks later from 2.0 mg collagenase injection, we observe histologic appearance like arthritis. Conclusion : In our study using injection of collagenase in temporomandibular joint of rabbit we produce arthritis on temporomandibular joint of rabbit.

레이저와 2차원 배열의 광전검출기를 이용한 구조물의 변위측정 시스템의 개발에 관한 연구

강문필,이진이,김민수,김대정,최원하,강기훈,김종수,김훈 한국비파괴검사학회 2002 한국비파괴검사학회지 Vol.22 No.1

일반적으로 구조물은 외부의 정적 및 동적 하중과 외부환경으로 인하여 피로균열과 부식이 발생하며, 이것은 구조물의 변형을 유발하여 결국 파단으로 이어지기 때문에 균열과 부식의 검출 및 평가와 함께 구조물의 변형에 의한 진동, 변위 기울기와 같은 거동을 감시하는 것도 매우 중요하다. 이에 레이저 센서 시스템을 이용하여 이러한 거동을 측정하여 이상 유무를 모니터링할 수 있는 구조물 안전감시 시스템을 개발하였다. 본 시스템은 2차원으로 배열한 광전센서를 이용하여 구조물의 변형에 의해 유발된 광궤적의 변화를 감시하며 또한 데이터를 취득하고 신호처리 할 수 있는 운용 프로그램도 갖추고 있다. 본 연구에서는 개발한 안전 진단 시스템의 필드 적용에 앞서 실험실에서의 몇 가지 실험을 통하여 그 효용성을 검증하였다. A Safety Monitoring System using a laser and 2-D arrayed photo sensors is developed. To monitor of the deformation and small rotation of structure the developed optical system using 2-D photo sensor array was used to detect the variation of optical orbit of laser which was induced by deformation of the structure. Also, an operating program to manage the system and an algorithm for the data acquisition and the database are introduced. In this study, we demonstrated the capabilities of this system by laboratory experiments before applying the system to the field.

악안면 영역에서의 유리 전완피판술 적용례분석

김욱규,송원욱,황대석,김용덕,신상훈,김종렬,정인교 부산대학교 병원 암연구소 2009 부산대병원학술지 Vol.- No.25

구강내 악성흑색종에 대한 임상연구

김욱규,허진호,황대석,김용덕,신상훈,김종렬,정인교 부산대학교 병원 암연구소 2008 부산대병원학술지 Vol.- No.23

The prognosis of oral malignant melanoma is poor compared with cutaneous melanoma. It may be related to the difficulty of wide enough resection, the early hematogenous matastases, higher stage at initial diagnosis, tendency to growth vertically. In the view of histological differences between oral mucosa and skin, it is impossible use Clark’s and Breslow’s classifications for prognosis. The great problem is that there is still no consensus on the treatment due to rarity. Because data collection from case reports is considered to be the best source of information and should be pooled to anlalyze key determinants of outcome, We reported on 6 cases of primary malignant melanoma of the oral cavity which were diagnosed and treated in Pusan National University Hospital recently and reviewed the literature. Immunohistochemical study on S100 Protein, GP 100 (HMB-45) with biopsy was usable to confirm the melanoma. Neck dissection including wide excision is recommended if lymph node involvement is suspected. Additionally, adjuvant chemotherapy could be supporting therapy.

2021년도 1학기 신라대학교 재학생의 부산인식 설문조사 분석 : 관광경영학부생을 대상으로

김대래 · 양승훈 · 장희정 신라대학교 부산학연구센터 2021 부산연구 Vol.19 No.1

이 연구는 매학기 신라대학교 재학생을 대상으로 이루어지는 설문조사 분석의 일환으로 작성되었 다. 2021년도 1학기에는 국제관광경영학부 학생들을 대상으로 설문조사를 하였다. 응답자는 원래 108명이었으나 그 가운데 부산에서 출생한 56명을 대상으로 분석하였다. 학생들의 종교와 아버지와 어머니의 고향 그리고 부산의 대표적인 음식과 장소에 대한 학생들의 인식을 조사하였다. 또 부산사 람들의 좋은 성격과 나쁜 성격이 무엇인가에 대해서 조사하였다. 아울러 부산에 어떤 것이 새로 생 기면 좋은지에 대해서 물어보았다. 또한 학생들이 좋아하는 음료와 1주일에 술마시는 횟수를 조사하 였으며 한달에 용돈을 얼마 쓰는가를 분석하였다. 이러한 분석을 통하여 대학생들이 부산에 대해 어 떻게 생각하고 또 어떤 생활을 하고 있는가를 부분적이지만 알 수 있었다. 그리고 이러한 연구가 계 속되어 축적이 되면 훗날 부산을 이해할 수 있는 좋은 자료가 될 것으로 기대된다.

연쇄상구균의 약제내성과 전이성 R-plasmid의 특성

김종훈,임대환,이창훈,이수정,이월라,황미혜,김은희 한국어병학회 2003 한국어병학회지 Vol.16 No.1

본 연구는 넙치 병어에서 분리된 연쇄상구균들의 항균제 내성 경향을 파악하고, 약제내성의 전이에 관여하는 R plasmid를 검출하여, 분리 균들 내에서 이들 plasmid의 분포를 알아보기 위하여 실시하였다. 넙치 병어에서 분리된 연쇄상구균 40 균주의 대부분은 ampicillin, doxycycilne (DOXY), erythromycin, florfenicol, flumequine, norfloxacin, osolinic acid, oxytetracycline (OTC)의 2~5약제에 동시내성을 나타내었다. 이들 내성균으로부터 내성 전이에 관여하는 R plasmid (pST9)가 검출되었으며, OTC와 DOXY내성이 R plasmid에 의하여 수용균인 Streptococcus sp.로 전이가 이루어졌다. 전이성 R plasmid의 분포를 알아보기 위하여 colony 혼성화 반응을 실시한 결과, 40 분리 균주 중 6 균주에 동일한 DNA 구조의 R plasmid가 존재하는 것으로 나타났다. 그러므로 이들과 DNA 구조가 다른 R plasmid도 넙치병어에서 분리되는 연쇄상구균의 약제내성에 관여하고 있음을 시사하였다. MICs of 8 chemotherapeutic agents against forty streptococcal isolates were determined. These strains were isolated from diseased olive flounder, Paralichthys olivaceus, and showed 2~5 multiple drug resistance against different antibacterial agents including ampicillin, doxycycline (DOXY), erythromycin, florfenicol, flumequine, norfloxacin, oxolinic acid, and oxytetracycilne (OTC). In conjugation experiment, we found transferable R plasmids carrying OTC and DOXY resistance determinant in 3 drug resistance strains analyzed. Six out of 40 isolates showed positive signal in colony hybridization with the R plasmid DNA (pST9) as a probe. It suggests that other types R plasmid different from pST9 is also involving in multiple drug resistance of streptococci isolated from olive flounder.

분자역학적 방법을 이용한 부산시내 대형건물 냉각탑수의 레지오넬라균의 형별 분류

김정만,정석훈,서대영,박은희,송은주,최재철,이은엽,장철훈 대한임상미샐물학회 2004 Annals of clinical microbiology Vol.7 No.1

구강내 결손부에 적용된 연조직 재건술식들에 대한 임상적 고찰

김욱규,이승환,황대석,김용덕,신상훈,김종렬,정인교 부산대학교 병원 암연구소 2007 부산대병원학술지 Vol.- No.21

To evaluate criteria, indications, and prognosis of the various reconstructive methods on the patients with intraoral soft tissue defect who had been treated at Dept. of Oral and Maxillofacial Surgery, Pusan National University Hospital from 2003 to 2005, we have reviewed the clinical data of the patients and analysed. The results were as follows: 1. Tongue flaps have been mainly applied on anterior portion of palate and maxilla. The survival rate was high percent, but the cooperation of patient was inevitable for the success. 2. Palatal mucosa rotational flaps were available on relative large defect on palate, oroantral fistula site. The side effect was a scaring band from secondary healing on denuded donor palate site. Sometimes the band came to be a hinderance to swallowing, phonation. 3. The application of free skin graft on entire maxilla site , palate was possible. The skin from thigh, abdomen could be applicable on fixed or movable tissues. The advantages of abdominal skin were easy harvest and direct donor site closure. 4. Forearm free flap was a workhorse flap for everywhere in intraoral defects. We had used the flap on cheek, floor of mouth, tongue without any significant complications. But the application of the flap was required for long operation time, which was disadvantageous to the old, weak patients. 5. Cervical platysmal flap could be easily applicable for buccal cheek, floor of mouth after excision of the cancer lesion. the design of the flap could be made simultaneously on neck dissection, but the danger of cancer remnants on the flap always might be remained. 6. Buccal fat pad pedicled flap must have been a primary flap for repair of oroantral fistula especially on posterior maxilla. The flap survival will be expected if the considerations for above reconstructivε methods on site, size, condition of defects primarily could be made.

에어로빅 웨이트트레이닝과 에어로빅 운동이 비만 여중생의 건강체력과 체조성에 미치는 영향

김기봉,김동훈,강대관 한국스포츠리서치 2003 한국 스포츠 리서치 Vol.20 No.1

The purpose of this study was to analyze the effect of aerobic dance and aerobic weight training on health-related physical fitness and body composition in the in obese middle school girls who participated in regular and continuous exercise 12 weeks. 1. Differences and change of health-related physical fitness 1) Back muscle strength was significantly higher in Aerobic Dance Group than Aerobic Weight Training Group, and there were not significant differences in sit-ups, sit-and-reach and 800m run tine between two groups before training session, but there were not significant differences in all fitness factors between two groups after 12-week training. 2) In the changes of health-related fitness factors in each group before and after training, sit-and-reach and 8001n run time were significantly improved, but back muscle strength and sit-ups were not improved in Aerobic Dance Group, and back muscle strength, sit-ups and sit-and-reach were significantly improved, but 800111 run time was not improved in Aerobic. Weight Training Group. 2. Differences and Changes of Body Composition 1) There were not significant differences in all factors of body composition between two groups before and after training. 2) In the changes of body composition factors in each group before and after training, body weight, body fat and body mass index were significantly decreased, but %fat and lean body mass were not significantly changed in two groups.

초등학교 과학수업에서 교사의 학습 동기 전략 분석

김동욱,이성숙,강대훈,백성혜 한국초등과학교육학회 2004 초등과학교육 Vol.23 No.1

The purpose of this study was to define teachers' learning motivation strategies and students' responses by analyzing science classes and interviews. The subjects were first grade and sixth grade teachers and students of an elementary school. The analysis tools are based on Keller's ARCS theory. The differences of teachers' motivation strategies were analyzed by grades and teachers' and students' backgrounds. The interviewers were composed of three teachers and three students of first grade, and three teachers and three students of sixth grade. The data were collected by recording of the classes using tape recorders, video cameras, and notebooks written by researchers. The results are as follows. First, teachers had their own styles of teaching strategies in their classes. Especially teachers' teaching backgrounds affected on the teachers' instructional strategies. The teachers who had long teaching experiences of lower grade students used to show a lot of attention strategies. While the teachers with long teaching experiences of higher grade students used to show few learning motivation strategies. Especially, sixth grade teachers used to show fewer confidence strategies than first grade teachers. Second, all of the teachers used to show few satisfaction strategies commonly in all the classes observed. Third, the students' recognition of the motivation strategies were not different according to their conceptions or activities of the classes. Commonly first grade students focused on the attention strategies, while sixth grade students focused on negative motivation strategies. Fourth, the teachers who believed that students need detail guidance and control recognized the needs of satisfaction strategies by students' autononmous activities after observing video tapes of other teachers' classes.