Safety and Efficacy of the Endeavor ResoluteⓇ Stent in Patients with Multivessel Disease: The HEART (Honam EndeAvor ResoluTe) Prospective, Multicenter Trial

심두선,정명호,홍영준,김주한,안영근,박근호,황선호,강동구,이승욱,김준우,박종필,류재영,이상록,채제건,윤경호,오석규,Won You Kang,김수현,조장현 전남대학교 의과학연구소 2018 전남의대학술지 Vol.54 No.1

The Endeavor ResoluteⓇ (ER) is a zotarolimus-eluting stent (ZES) with a biocompatibleBioLinx polymer. This study prospectively compared the clinical outcomes of 2 versionsof ZES, ER and Endeavor SprintⓇ (ES), in patients with multivessel disease. A totalof 488 patients who underwent multivessel percutaneous coronary intervention (PCI)were divided into 2 groups the ER group (n=288) and the ES group (n=200). The primaryendpoint was a composite of major adverse cardiac events (MACE) consisting of death,myocardial infarction, and target vessel revascularization after 12 months. In all patients,the prevalence of diabetes was higher in the ER group (42.7% vs. 31.0%, p=0.009). The rate of post-PCI Thrombolysis in Myocardial Infarction flow grade 3 was higherin the ER group (100.0% vs. 98.0%, p=0.028). There were no between-group differencesin the in-hospital, 1-month and 12-month clinical outcomes. In the propensity scorematched cohort (n=200 in each group), no differences were observed in the baseline andprocedural characteristics. There were no statistical differences in the rates of in-hospital,1-month and 12-month events (12-month MACE in the ER and ES groups: 6.0%vs. 3.5%, p=0.240, respectively). The safety and efficacy of both versions of ZES werecomparable in patients with multivessel disease during a 12-month clinical follow-up.

태권도를 통한 인성교육적 가치 유형

최유리(Choi, You-Lee),홍영준(Hong, Young-Jun),김지혁(Kim, Ji-Hyuk) 한국체육과학회 2017 한국체육과학회지 Vol.26 No.2

The purpose of this study was to investigate the Value of Character Education types and characteristics. In order to purpose of this study, Q methodology was employed. 20 majored in Taekwondo student were selected. Q-sampling, the measuring instrument, collected the statements based on open-ended questions materials and statements from 217. The Q-population consisted of 27 statements to be collected out of which 25 Q-samples were selected. Results of Q-sorting were coded and analysed using QUANL pc program. The result is as follows. There are 4 types in the value of character education types. First type is Self-efficacy group. Second, the most important to respect of parents and loving them. Third, the most important to educational value of manners type. fourth type is self-control capability group. It was show that, According to Taekwondo student’s educational value allows characteristics. In result, Taekwondo has many factors in educational value, and an effective character education.

태권도 시범학교의 수업만족도와 수업효과 및 지속여부 분석

안용규 ( Yong Kyu Ahn ),안재찬 ( Jae Chan An ),홍영준 ( Young Jun Hong ),임지광 ( Ji Kwang Lim ),박장기 ( Jang Ki Park ),김동석 ( Dong Seok Kim ),조성천 ( Sung Chun Cho ),최유리 ( You Lee Choi ) 국기원 2016 국기원태권도연구 Vol.7 No.1

이 연구는 2015학년도 제2학기부터 실시된 태권도 시범학교의 태권도 수업에 대한 학생들의 인식 수준을 평가하는 목적으로 전국 태권도 시범학교 12개 학교 총 2,118명의 자료를 분석하여 다음과 같은 결과를 도출하였다. 태권도 시범학교 태권도 수업에 참여하고 있는 학생들은 수업만족도, 수업효과, 지속여부에 대해 비교적 높은 수준으로 평가하고 있다. 수업 만족도의 하위요 인에서는 지도자가 가장 높았으며, 수업내용, 시설/환경, 흥미의 순으로 나타났다. 수업만족도에 대해 남학생이 여학생 보다 높은 수준으로 평가하며, 하위요인 중 특히 지도자, 시설/환경에서 높게 평가하고 있었다. 또한 학교급에 따른 수업만족도의 차이에서는 고등학생이 중학생에 비해 높게 평가하며, 고등학생은 하위요인 중 지도자, 시설/환경에서 중학생에 비해 높게 평가하고 있었다. 태권도장 경험에 따른 차이에서는 태권도장 유경험 학생이 무경험 학생보다 높게 평가 하며, 하위요인 중 수업내용, 지도자, 흥미에서 유경험 학생이 무경험 학생보다 높게 평가하고 있었다. 수업효과에서는 성별, 학교급에 따른 유의한 차이는 없었으며, 태권도장 경험에 따른 차이에서 태권도장 유경험 학생이 무경험 학생보다 높게 평가하고 있었다. 지속여부에서는 성별, 학교급에 따른 유의한 차이는 없었으며, 태권도장 경험 유무에 따른 차이에서 태권도장 유경험 학생이 무경험 학생보다 높게 평가하고 있었다. This study has obtained the following results based on data analysis on 2,118 students from twelve Taekwondo model schools nationwide to evaluate the cognition level of the students on their experience on Taekwondo classes during the second semester of 2015. Students have rated satisfactory for satisfaction, effect, and sustainability of Taekwondo classes. Instructors were listed as the top reason for low satisfaction rate, along with facility/environment. For class satisfaction, male students gave higher scores compared to female students, and high school students than middle school students. High school students so gave higher scores for instructors and facility/environment compared to middle school students. Previous experience with Taekwondo showed difference also; students with previous experience with Taekwondo gave higher score, especially for items such as class contents, instructor, and interest. There were no significant difference between genders or class difference on the effects and sustainability of Taekwondo class, but once again, students with previous Taekwondo experience gave higher score for this item.

위암 발견에 있어 철결핍 지표들의 유용성

정진모(Jin Mo Jung),한철주(Chul Ju Han),홍영준(Young Joon Hong),조현호(Hyun Ho Cho),김영호(Young Ho Kim),최대현(Dae Hyun Choi),조상형(Sang Hyung Cho),조광희(Kwang Hee Cho),김진(Jin Kim),정숙향(Sook Hyang Jung),김유철(You Choul Kim) 대한소화기학회 2002 대한소화기학회지 Vol.39 No.3

Background/Aims: Cancers of the gastrointestinal tract might cause chronic occult blood loss leading to iron deficiency. The aim of this study was to determine the usefulness of the tests for iron deficiency in detection of stomach cancer. Methods: Seventy one patients with advanced gastric cancer (AGC), 13 patients with early gastric cancer (EGC), and 104 patients with functional GI disorder (FGID) as a control were consecutively enrolled in this study. The test results for iron-deficiency parameters such as hemoglobin, serum ferritin, serum iron, total iron binding capacity, and transferrin-saturation rates were compared among the groups. Incidence of iron deficiency or anemia was compared among the groups. Results: The levels of hemoglobin, serum ferritin, serum iron, and the rates of transferrin saturation were significantly lower in the AGC group than in the control group. These differences were even marked in male patients. They were not significantly different between the EGC group and the control group. In male patients with AGC, the incidence of anemia or iron deficiency was markedly higher than the control group. Conclusions: In males over 50 years, tests for iron-deficiency parameters such as hemoglobin, serum ferritin, serum iron, and transferrin saturation might be helpful in detection of AGC. Further study is needed to reveal whether these tests are helpful in the early detection of stomach cancer. (Korean J Gastroenterol 2002;39:179-185)

영구형 심박동기 삽입 후 유의한 삼첨판 역류증 발생의 예측인자

이경진 ( Kyoung Jin Lee ),김계훈 ( Kye Hun Kim ),임이랑 ( Yi Rang Yim ),박혁진 ( Hyuk Jin Park ),이승헌 ( Seung Hun Lee ),김지은 ( Ji Eun Kim ),정형기 ( Hyung Ki Jeong ),윤현주 ( Hyun Ju Yoon ),윤남식 ( Nam Sik Yoon ),홍영준 ( You 대한내과학회 2014 대한내과학회지 Vol.86 No.5

Background/Aims: We sought to identify predictors of significant tricuspid regurgitation (TR) after successful permanent pacemaker (PPM) implantation in Korean patients. Methods: Of 404 patients who underwent PPM implantation, 187 patients who had both baseline and follow-up echocardiographic examinations were assigned to one of two groups: no development or change in TR (Group I, n = 172, 65.5 ± 13.7 years) versus the development of significant TR (Group II, n = 15, 72.1 ± 8.3 years). Clinical, laboratory, and echocardiographic variables were compared between the two groups. Results: Overall, the grade of TR was significantly aggravated from 0.46 ± 0.73 to 0.81 ± 0.84 (p < 0.001) during 3.1 ± 1.8 years of follow-up (0.49 ± 0.75 to 0.69 ± 0.74 in Group I, p < 0.001; 0.13 ± 0.35 to 2.27 ± 0.46 in Group II, p < 0.001). The de novo development or aggravation of TR was observed in 66 patients (35.3%), and significant TR developed in 15 patients (8.0%). The presence of atrial fibrillation (AF) was significantly higher (53.3 vs. 18.6%, p = 0.002), and the implantation of a ventricle pacing, ventricle sensing, inhibited by ventricular event (VVI) type pacemaker was more frequent in Group II than in Group I (46.7 vs. 15.1%, p = 0.002). Other variables were not different between the groups. Conclusions: The development or aggravation of TR was not rare after successful PPM implantation, even though the development of significant TR was uncommon. The presence of AF and the implantation of a VVI type pacemaker were predictors of the development of significant TR. Together, the results of this study suggest that the development or aggravation of TR should be monitored carefully after PPM implantation. (Korean J Med 2014;86:577-584)

만성 간질환과 간세포암종 환자에서 Basic Fibroblast Growth Factor와 Vascular Endothelial Growth Factor의 혈청 농도

김창민,홍석일,이진옥,유성재,정성문,정숙향,이진오,한철주,김종광,송용환,홍영준,김유철 대한간학회 2001 Clinical and Molecular Hepatology(대한간학회지) Vol.7 No.1

Background/Aims: Angiogenesis occurs in response to tissue damage, and is of vital importance for tumor growth and metastasis. Basic fibroblast growth factor (bFGF) and vascular endothelial growth factor (VEGF) are potent angiogenic factors, and have been suggested to be useful diagnostic markers in certain hypervascular tumors. However, little is known of serum bFGF and VEGF in patients with hepatocellular carcinoma (HCC). We attempted to measure serum bFGF and VEGF in patients with chronic liver diseases (CLD) and HCC to assess their pathogenetic role and usability as tumor markers. Methods: Serum bFGF and VEGF were measured in 8 patients with chronic hepatitis (CH), 15 patients with liver cirrhosis (LC), and 49 patients with HCC. bFGF was measured in 33, and VEGF was measured in 50, healthy blood donors. Results: Serum bFGF was 3.8±1.9, 2.0±1.4, 4.2±6.0, 17.4±30.0 pg/mL in normal control, CH, LC, HCC, respectively. The serum bFGF level was significantly increased in patients with HCC when compared withmal control or patients with CLD. No difference, however, was observed in serum VEGF levels among the four groups. The serum levels of bFGF and VEGF were not significantly different in patients with HCC according to tumor type, size and stage. Serum bFGF showed good sensitivity (90%), specificity (87%), and positive predictive value (94%) in differentiating patients with HCC from those with CLD at the cut-off value of 4.6 pg/mL. Conclusions: bFGF might play a role in the growth of HCC and its serum level might be used as a tumor marker. On the other hand, serum VEGF does not seem to be an adequate tumor marker.(Korean J Hepatol 2001;7:47-54)