http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
최홍상,Kim Bongseong,Han Kyungdo,오태렴,서상헌,김민아,김창성,배은희,마성권,김수완 대한신장학회 2023 Kidney Research and Clinical Practice Vol.42 No.1
Background: Several studies have reported that depression is prevalent in patients with diabetes or chronic kidney disease. However,the relationship between weight changes and the risk of depression has not been elucidated in patients with diabetic kidney disease(DKD).Methods: From the Korean National Health Insurance Service database, we selected 67,866 patients with DKD and body weightdata from two consecutive health examinations with a 2-year interval between 2009 and 2012. Weight change over 2 years was categorizedinto five groups: ≥–10%, <–10% to ≥–5%, <–5% to <5%, ≥5% to <10%, and ≥10%. The occurrence of depression was monitoredvia the codes of International Statistical Classification of Diseases, 10th revision through the end of 2018.Results: During the 5.24-year follow-up, 17,023 patients with DKD developed depression. Weight change and the risk of depressionhad a U-shaped relationship: patients with ≥–10% weight change (hazard ratio [HR], 1.12) and those with ≥10% weight change (HR,1.11) showed higher HRs for depression than those with <–5% to <5% weight change, even after adjusting for several confoundingfactors. In the subgroup analyses, the risk of depression tended to increase as weight gain or weight loss increased in all subgroups.Conclusion: Both weight loss and weight gain increased the risk of depression in patients with DKD.
최홍상,정명호,서일국,이민구,고점석,박근호,심두선,윤남식,김계훈,박형욱,홍영준,김주한,안영근,조정관,박종춘,강정채 대한심장학회 2011 Korean Circulation Journal Vol.41 No.7
Stent thrombosis is a fatal complication in patients who have undergone percutaneous coronary intervention, and discontinuation of anti-platelet agent is a major risk factor of stent thrombosis. We report a rare case of very late stent thrombosis (VLST) following discontinuation of anti-platelet agents in a patient who experienced acute myocardial infarction and essential thrombocytosis. She had undergone implantation of a drug eluting stent (DES) and a bare metal stent (BMS) two and half years prior to her presentation. VLST developed in DES, not in BMS, following interruption of anti-platelet therapy.
만성 콩팥병 환자에서 고혈압의 진단 기준 Update: 2017 ACC/AHA 고혈압 가이드라인의 적용
최홍상 ( Hong Sang Choi ) 대한내과학회 2019 대한내과학회지 Vol.94 No.3
Hypertension affects the majority of patients with chronic kidney disease (CKD) and increases the risk of cardiovascular disease, end-stage renal disease and mortality. Previously, many hypertension guidelines have suggested blood pressure targets in patients with CKD. Recently, the American College of Cardiology/American Heart Association 2017 Guideline for Hypertension suggests a new definition for hypertension and therapeutic targets, which were equally applicated to patients with CKD. These changes reflect the results of the Systolic Blood Pressure Intervention Trial (SPRINT) study, but the renal outcome of intensive blood pressure control was not good. Furthermore, the majority of hypertension guidelines including those of the Korean Society of Hypertension and the European Society of Hypertension have retained the traditional definition. Herein, we intend to analyze in detail the effect of intensive blood pressure control on kidney through the post-hoc analyses of the SPRINT study. (Korean J Med 2019;94:263-267)
최홍상 ( Hong Sang Choi ),김수완 ( Soo Wan Kim ) 대한내과학회 2016 대한내과학회지 Vol.91 No.1
The most recent revision of the blood pressure guidelines adopted less aggressive blood pressure targets, particularly in patients with diabetes and chronic kidney disease, and the elderly. However, the Systolic Blood Pressure Intervention Trial (SPRINT) reported that lowering the systolic blood pressure to < 120 mmHg resulted in a decreased risk of cardiovascular disease, compared with lowering the SBP to < 140 mmHg, in adults with hypertension but without diabetes. This will likely lead to many changes in clinical practice. Such lowering of systolic blood pressure would benefit some categories of hypertensive patients at an increased risk of cardiovascular disease. (Korean J Med 2016;91:12-17)
Optimal blood pressure target and measurement in patients with chronic kidney disease
김창성,최홍상,배은희,김수완,마성권 대한내과학회 2019 The Korean Journal of Internal Medicine Vol.34 No.6
The prevalence rates of hypertension and chronic kidney disease (CKD) are increasing with the aging of the population. Hypertension and CKD are closely related, and hypertension with accompanying CKD is difficult to control. This difficulty controlling blood pressure (BP) can be explained by changes in diurnal variation in BP, such as non-dipping and reverse dipping patterns, increased pulse pressure, and BP variability in CKD patients resulting in a high frequency of nocturnal hypertension or masked hypertension. CKD patients with uncontrolled or nocturnal hypertension are at increased risk for cardiovascular disease, progression of CKD, and all-cause death. Recent studies have shown that intensive reduction of systolic BP below 120 mmHg is seems to favor in CKD patients regardless of the presence or absence of diabetes. As BP control is difficult in patients with CKD, appropriate measurement of BP is important. Automated BP monitoring could reduce the so-called “white coat effect” (spike in BP) that may be triggered by measurement in a clinical setting. Moreover, out-of-office BP monitoring at home or ambulatory BP monitoring for 24 hours may provide critical information regarding diurnal BP variability and nocturnal BP in patients with CKD.
송수현,최홍상,배은희 대한내과학회 2022 대한내과학회지 Vol.97 No.3
Secondary hypertension, which refers to arterial hypertension caused by an identifiable medical condition, accounts for 5-10% of all hypertensive diagnoses; however, this is thought to be an underestimate. If diagnosed promptly, secondary hypertension can be treated, and proper blood pressure restored. This review focuses on the screening, diagnosis, and management of the most common forms of secondary hypertension, including primary aldosteronism, renovascular hypertension, pheochromocytoma, Cushing’s syndrome, and renal parenchymal disease.