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- 저자 : 최홍상 ( Hong Sang Choi ) (검색결과 3 건)
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최홍상 ( Hong Sang Choi ),김수완 ( Soo Wan Kim ) 대한내과학회 2016 대한내과학회지 Vol.91 No.1
The most recent revision of the blood pressure guidelines adopted less aggressive blood pressure targets, particularly in patients with diabetes and chronic kidney disease, and the elderly. However, the Systolic Blood Pressure Intervention Trial (SPRINT) reported that lowering the systolic blood pressure to < 120 mmHg resulted in a decreased risk of cardiovascular disease, compared with lowering the SBP to < 140 mmHg, in adults with hypertension but without diabetes. This will likely lead to many changes in clinical practice. Such lowering of systolic blood pressure would benefit some categories of hypertensive patients at an increased risk of cardiovascular disease. (Korean J Med 2016;91:12-17)
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만성 콩팥병 환자에서 고혈압의 진단 기준 Update: 2017 ACC/AHA 고혈압 가이드라인의 적용
최홍상 ( Hong Sang Choi ) 대한내과학회 2019 대한내과학회지 Vol.94 No.3
Hypertension affects the majority of patients with chronic kidney disease (CKD) and increases the risk of cardiovascular disease, end-stage renal disease and mortality. Previously, many hypertension guidelines have suggested blood pressure targets in patients with CKD. Recently, the American College of Cardiology/American Heart Association 2017 Guideline for Hypertension suggests a new definition for hypertension and therapeutic targets, which were equally applicated to patients with CKD. These changes reflect the results of the Systolic Blood Pressure Intervention Trial (SPRINT) study, but the renal outcome of intensive blood pressure control was not good. Furthermore, the majority of hypertension guidelines including those of the Korean Society of Hypertension and the European Society of Hypertension have retained the traditional definition. Herein, we intend to analyze in detail the effect of intensive blood pressure control on kidney through the post-hoc analyses of the SPRINT study. (Korean J Med 2019;94:263-267)
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김현국 ( Hyun Kuk Kim ),박종춘 ( Jong Chun Park ),김성수 ( Sung Soo Kim ),최홍상 ( Hong Sang Choi ),심두선 ( Doo Sun Sim ),윤남식 ( Nam Sik Yoon ),윤현주 ( Hyun Ju Yoon ),홍영준 ( Young Joon Hong ),박형욱 ( Hyung Wook Park ),김주 대한내과학회 2009 대한내과학회지 Vol.77 No.1
Background/Aims: The elasticity of the aorta modulates the entire cardiovascular system. Increasing arterial stiffness with the loss of aortic elasticity is not only a surrogate marker for early atherosclerosis, but also a predictor of cardiovascular events. Methods: This study included 203 patients (57.6±14.7 years, 117 male) who underwent diagnostic transesophageal echocardiography. We investigated the correlation between the arterial stiffness index (β stiffness index), which is calculated from the distensibility of the descending thoracic aorta and blood pressure, and known serologic markers of atherosclerosis and cardiovascular events. Results: The β stiffness index correlated significantly with the brachial-ankle pulse wave velocity (R2=0.243, p<0.001) and in-tima-media thickness of the descending thoracic aorta (R2=0.470, p<0.001). It also correlated with age (r=0.465, p<0.001) and the presence of diabetes mellitus (r=0.250, p<0.001). The β stiffness index was significantly positively correlated with the levels of N-terminal pro-brain natriuretic peptide (NT-proBNP), high-sensitivity C-reactive protein (hsCRP), glucose, HbA1c, apolipoprotein (Apo) A-I, and erythrocyte sediment rate. A multivariate regression analysis demonstrated that the β stiffness index was associated with the levels of NT-proBNP, hsCRP, HbA1c, and Apo A-I. Conclusions: The β stiffness index for the distensibility of the descending thoracic aorta significantly correlates with other parameters of arterial stiffness and serologic markers for atherosclerosis. Therefore, the β stiffness index can be used as a parameter of cardiovascular events in diseases requiring transesophageal echocardiography, such as atrial fibrillation and mitral stenosis. (Korean J Med 77:68-75, 2009)
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