일부 한국 아동의 철분과 아연 섭취 및 배설에 관한 연구

최인선,이경화,오승호 대한지역사회영양학회 1998 대한지역사회영양학회지 Vol.3 No.1

In this study, the food intake, feces and urine of 14 primary school age boys and girls were collected and intake and excretion of iron and zinc were measured. The boys and girls were 8-12 years old and measurement continued for four weeks during which they maintained their normal living pattern. Each boy's and girl's daily intake and excretion of iron and zinc were measured and apparent digestibility and balance were also calculated. The results are as follows. Mean daily intake of iron was $14.9\pm{0.6mg}$ for the boys and $12.4\pm{0.5mg}$ for the girls. Mean daily intake of zinc was $11.8\pm{1.2mg}$ for the boys and $11.5\pm{0.4mg}$ for the girls. Mean daily fecal loss and apparent digestibility of iron was $6.1\pm{0.3mg}$ and $58.8\pm{2.0%}$ for the boys and $6.8\pm{0.1mg}$ and $44.1\pm{2.0%}$ for the girls. Mean daily fecal loss and apparent digestibility of zinc was $9.3\pm{0.2mg}$ and $14.4\pm{5.1%}$ for the boys and $9.7\pm{0.4mg}$ and $14.3\pm{4.3%}$ for the girls. Mean daily urinary loss of iron was $1.1\pm{0.1mg}$ and showed the positive balance of $7.86\pm{0.6mg}$ for the boys and $0.5\pm{0.1mg}$ and showed the positive balance of $5.14\pm{0.4mg}$ for the girls. Mean daily urinary loss of zinc was $0.5\pm{0.1mg}$ and showed the positive balance of $1.03\pm{0.6mg}$ for the girls.

전쟁과 평화의 웃음의 시학

최인선 한국외국어대학교(글로벌캠퍼스) 러시아연구소 2020 슬라브연구 Vol.36 No.2

톨스토이의 문학세계를 구성하는 중심축은 자율성과 보편성, 부분과 전체 간의 대립과 융합에 관한 문제이다. 톨스토이는 이러한 주제 의식을 형상화하기 위해 다양한 문학적 장치들을 고안했는데, 그중 본 논문에서는 웃음에 주목하였다. 불일치이론에 따르면 웃음은 논리적인 모순과 기대한 것과 실제 일어난 것 사이의 불일치에서 비롯된다. 이러한 불일치는 타자의 모순성이 보편적 상식 및 윤리관과 어긋날 때와 역으로 보편적이고 절대적이라고 믿고 있었던 가치체계가 거짓되고 모순됨이 드러나는 경우와 연관된다. 전쟁과 평화에서도 웃음은 보편적 윤리관과 상충하는 현상에 대한 비판과 진리라고 믿고 있었던 가치체계를 해체하고 개체성과 보편성 사이의 내밀한 상호작용을 인식하는 것과 밀접하게 연관된다. 이러한 측면에서 웃음에 대한 이해는 전쟁과 평화의 문학성을 파악하는 데 도움이 될 것이다. The central theme of the literary world of Tolstoy pivots on the opposition and fusion between autonomy and universality, and part and whole. To embody this theme, Tolstoy created various literary devices. This paper will focus on the laughter. According to the mismatch theory, laughter derives from the mismatch between what was expected and what has happened. This mismatch is connected to the disagreement between contradiction in others and universal common sense and ethics. Further, the mismatch is, conversely, connected to the falsehood and contradiction, as found in a value system that was previously perceived as universal and absolute. In War and Peace, laughter is used to deconstruct the value system—which was previously believed as truth qua criticism on phenomena that clash with universal ethics—and embody the intimate interaction between individuality and universality. In this light, understanding laughter helps figure out the literary quality of War and Peace.

포스터 전시 : 감염, 알레르기 ; 전신 스테로이드에 의한 저감마글로불린 혈증을 보인 천식 1례

최인선,명대성,김상훈,서성례 대한내과학회 2005 대한내과학회 추계학술대회 Vol.69 No.10

보중익기탕(補中益氣湯) 및 그 가미방(加味方)을 투여한 중풍환자에 대한 임상적 고찰

최인선,민성순,김종환,서상호,박상은,김영균,권정남,Choi, In-Seon,Min, Sung-Soon,Kim, Jong-Hwan,Seo, Sang-Ho,Park, Sang-Eun,Kim, Young-Kyun,Kwon, Jung-Nam 대한한방내과학회 2004 大韓韓方內科學會誌 Vol.25 No.3

Object: This study was designed to investigate the clinical and practical characteristics of stroke patients treated with the age-old herbal medicines, Bojungikki-tang and Bojungikki-tang-gamibang. Methods: The 80 patients studied were all diagnosed with stroke by neurological examination, B-CT and B-MRI scan. They were treated with Bojungikki-tang and Bojungikki-tang-gamibang over 5 days and symptoms were observed. There were inpatients and outpatients at the Oriental Medical hospital of Dong-eui University from January in 2000 to June in 2003. All patients were interviewed and medical charts examined. Result and Conclusion: The results were found: 1.Many were in their sixties. Average age was 64.54. 2.Cerebral infarction was diagnosed in 86.25% of all cases. 3.30% of stroke cases occurred in spring. 4.Average blood pressure was 129/84mmHg on the fifth day of treatment with Bojungikki-tang and Bojungikki-tang-gamibang and 135/86mmHg on the first day. 5.The white color were best in facial color about 85.29%. 6.There were many who returned for treatment within 6 to 10 days. 7.Bojungikki-tang and Bojungikki-tang-gamibang were used Rt. hemiplegia more than for Lt. hemiplegia.

興陽邑城과 고흥의 4개 鎭城에 대한 고찰

최인선 순천대학교 남도문화연구소 2002 南道文化硏究 Vol.8 No.-

국내 Acinetobacter 임상분리주 내 adeG, adeB, adeE, adeY, abeM 및 adeJ 유출 펌프 유전자의 분포

최인선,최지애,장숙진,박건,정석훈,김춘미,이오진,강성호,문대수 대한진단검사의학회 2019 Laboratory Medicine Online Vol.9 No.4

BackgroundThe aim of the present study was to determine the frequency of six efflux pump genes in Acinetobacter clinical isolates collected from South Korean hospitals. MethodsIn this study, we used a total of 339 Acinetobacter strains, comprising 279 Acinetobacter calcoaceticus–Acinetobacter baumannii (ACB) complex and 60 non-ACB complex strains. We performed specific PCR assays to detect adeG, adeB, adeE, adeY, abeM, and adeJ, transporter genes of the multidrug efflux pumps AdeFGH, AdeABC, AdeDE, AdeXYZ, AbeM, and AdeIJK, respectively. ResultsFrequencies of six efflux pump genes varied according to the species of Acinetobacter . Frequencies of adeE, abeM, and adeJ between A. baumannii group and A. nosocomialis group were found to be significantly different. Significant differences were found in the frequencies of adeB, adeE, adeY, and adeJ among the susceptible A. baumannii (SAB), multidrug-resistant A. baumannii (MDRAB), and extensively drug-resistant A. baumannii (XDRAB) groups within the 154 strains of A. baumannii. The frequencies of efflux pump genes in imipenem-susceptible and imipenemnonsusceptible groups were significantly different for adeB, adeY, and adeJ. The frequencies of efflux pump genes in ciprofloxacin-susceptible and ciprofloxacin-nonsusceptible groups were significantly different for adeB and adeY. No significant difference was found in the frequency of efflux pump genes among groups sampled from different regions of Korea, across 86 strains of A. baumannii collected in 2012. ConclusionsThe frequencies of six efflux pump genes obtained in this study demonstrate the fundamental epidemiological feature of efflux pump genes in Korean Acinetobacter clinical isolates. 배경본 연구의 목적은 국내의 병원들에서 수집된 Acinetobacter 임상분리주가 보유한 6가지 유출 펌프 유전자의 빈도를 측정하는데 있다. 방법본 연구에서 사용한 총 339주의 Acinetobacter 균주는 Acinetobacter calcoaceticus–Acinetobacter baumannii (ACB) complex 279주와 non-ACB complex Acinetobacter 60주로 구성되었다. 다약제 유출 시스템인 AdeFGH와 AdeABC, AdeDE, AdeXYZ, AbeM 및 AdeIJK 유출 펌프 각각의 운송(transporter) 유전자인 adeG와 adeB, adeE, adeY, abeM 및 adeJ 유전자를 검출하기 위해 각 유출 펌프 유전자에 특이적인 PCR 분석을 수행하였다. 결과adeG와 adeB, adeE, adeY, abeM 및 adeJ의 6가지 유출 펌프 유전자의 빈도는 14군의 Acinetobacter 균종별로 다양하게 나타났다. A. baumannii 군과 A. nosocomialis 군에서 adeE와 abeM, adeJ의 양성률은 두 균종 간에 유의한 차이가 있었다. A. baumannii 154주는 SAB, MDRAB, XDRAB 군별로 adeB와 adeE, adeY 및 adeJ의 빈도에 유의한 차이를 보였다. Imipenem-감수성군과 imipenem-비감수성군은 adeB와 adeY, adeJ의 양성률에 유의한 차이를 보였다. Ciprofloxacin-감수성군과 ciprofloxacin-비감수성군은 adeB와 adeY의 양성률에 유의한 차이를 보였다. 2012년에 수집한 86주의 A. baumannii는 수집지역별로 6가지 유출 펌프 유전자 모두 양성률에 유의한 차이가 없었다. 결론이 연구에서 얻어진 6가지 유출 펌프 유전자의 양성률은 국내 Acinetobacter 임상분리주 내 유출 펌프 유전자의 기본적인 역학적 특성을 보여주었다.

천식 의심환자들에서 기관지과민반응 양상에 관한 연구

최인선,박재희,이신석,강유호,정익주,박경옥 대한천식알레르기학회 1992 천식 및 알레르기 Vol.12 No.1

The presence of an increased airway responsiveness to histamine or to methacholine has been observed not only in asthmatics but in patients with chronic obstructive pulmonary disease, cystic fibrosis, or other cardiopulmonary diseases. However, it was suggested that some characteristic patternes of bronchial hyperresponsiveness(BHR) are specific for asthmatics. To evaluate the usefulness of methachoine broncial challenge as a specific diagnostic test of asthma, the relationship between the degree of BHR and the pattern of dose-response curve were analyzed in 393 subjects with suspected asthma. 1. The slope of dose-response curve measured by modified Oreheks method and the occurrence of no plateau determined by modified Woolcocks method were related to the severity of BHR(p<0. 001, respectively). And the relationship was continued during the improvement of bronchial responsiveness with antiasthma therapy in 20 patients with asthma.

천식 의심 환자들의 메타콜린 상부기도 과민성

최인선,강광원,고영일,홍서나 대한천식알레르기학회 2002 천식 및 알레르기 Vol.22 No.4

수학에서 컴퓨터 기반 학업성취도 평가 도입 방안 탐색

최인선 한국수학교육학회 2013 수학교육 학술지 Vol.2013 No.1

최근 여러 국가들이 국가 경쟁력 확보를 위해 국가정책의 중심에 교육을 두고 있으며, 이러한 교육정책들은 컴퓨터로 대표되는 정보화 매체들을 기반으로 인공적인 과제보다는 실제적인 과제들을 중심으로 하여 학습자들이 경쟁이 아닌 협동을 통해 지식을 능동적으로 받아들이고, 암기가 아닌 검색을 통한 학습이 이루어지도록 하는데 초점을 맞추고 있다. 현대 사회에서 요구하는 생산적인 시민이 되기 위해서는 기초적인 수학 지식을 활용하여 문제 상황을 해결하기 위해 컴퓨터나 계산기 등을 탐구 도구로 적극 활용하면서 여러 정보를 취사·선택하여 활용할 수 있는 능력이 필수적으로 요구된다. 이에 본 연구에서는 수학교과에서 컴퓨터 기반 평가 도구에 대한 필요성에 대해 알아보고, 평가 도구 개발을 위해 포함되어야 할 평가 요소들에 대해 살펴보고자 한다.

Usefulness of House Dust Mite Nasal Provocation Test in Asthma

최인선,김수정,원주민,박명수 대한천식알레르기학회 2017 Allergy, Asthma & Immunology Research Vol.9 No.2

Purpose: We previously reported that the skin prick test was sensitive and the serum specific immunoglobulin E test was specific for predicting positive airway responses to house dust mites (HDMs) in patients with asthma. Because the nose and bronchus are one airway, the nasal provocation test would be more specific for predicting the bronchial responses to HDM than the skin test. Methods: The allergy skin prick test and nasal and bronchial provocation tests using HDM (Dermatophagoides farinae) were performed in 41 young men (age, 19-28 years) who wanted military certification for asthma. The nasal responses to HDM was scored according to the severity of rhinorrhea, sneezing, and nose itching. Results: The prevalence of a positive skin prick test to HDM did not significantly differ between patients with (n=24) and without (n=17) an early airway reaction (EAR; 79.2% vs 70.6%, P=0.534). However, the prevalence of a positive nasal test was significantly higher in the airway responders than in the others (37.5% vs 0%, P=0.005). The concordance of a positive response to the nasal test (κ=0.332, P=0.004) but not to the skin prick test (κ=0.091, P=0.529) was significant with an EAR. The diagnostic sensitivity of the nasal test (37.5%) was lower than that of the skin prick test (79.2%), but the specificity was higher (100% vs 29.4%). Conclusions: The skin prick test is more sensitive, whereas the nasal test is more specific and accurate, for predicting an EAR to HDM in patients with asthma.