피지선모반의 임상 및 병리조직학적 고찰

최성관,전재복 ( Sung Koan Choi,Jae Bok Jun ) 대한피부과학회 1988 대한피부과학회지 Vol.26 No.3

Clinical observations were made on 63 cases on nevus sebaceus of Jadasshon. 52 of 63 cases were diagnosed on the basis of clinical and histopathologic findings during a period of 19 years from January 1969 to July 1987 at the Department of Dermatology, Kyungpook National University Hospital, with the remaining 11 cases diagnosed at other skin clinics in Taegu. Histopathologic examinations were made on 51 selected cases of the 63. The results were as follows : Clinical observations 1) The percentage of patients with nevus sebaceus of Jadasshon of total new outpatients was 0.12%. Of the 63 cases, males numbered 38 and females, 25, with a sex r atio of 1.5: 1. 2) Patients when first seen were most commonly in the age group of 10~19. 3) The most favorate sites were the scalp(83.3%) and face(13.3%). 4) The average size of the lesions was 2.23cm * 3.24cm with no difference among the age groups. Histopathological observations 1) The apparent proliferation of sebaceous glands was observed in 32 of 51 cases(62.7%). The degree of proliferation markedly increased in the age group of l0~19 and slightly decreased beyond this age group. Apocrine glands were present. in 17(33.3%), with a higher number of glands seen in the age group of 10~19. Immature hair follicles were found in 38(74.5%), with no changes according to aging. 2) The epidermal changes such as acanthosis(86.3%), papillomatosis(70.6%), hyperkeratosis(78.2%) and hypergranulosis(78.2%) predominated in the age group of 10-19, and severe but more gradual changes were noted 20 years of age on. 3) Inflammatory cell infiltration of moderate to marked degree was noticeable in 27(53%). The older the patients were, the more pronounced dermal infiltration was. 4) Six of 51 cases were complicated with basal cell carcinoma(3) and syringocystadenoma papilliferum(4). The tumors, which occurred beyond 30 years of age, showed a marked inflammatory cell infiltration.

음경의 비성병성 경화성 림프관염 2예

최성관(Sung Koan Choi),최인철(In Chul Choi),정상립(Sang Lip Chung),서순봉(Soon Bong Suh) 대한피부과학회 1987 대한피부과학회지 Vol.25 No.6

We report two cases of nonvenereal sclerosing lymphangitis of the penis in a 34-year old man and a 28-year-old man. This disorder is an uncommon condition characterized by asymptomatie, firm, cord-like lesion of unknown etiology. Histopathologic findings reveal hypertrophy and sclerosis of lymphatic vessel walls, and some cases show thrombus formation within dilated vessels. Both cases had typical clinical and histopathologic features. In case I, the lesion resolved spontaneously on several occasions for 10 years. Therefore we argue that some individual rnay be predisposed to develop the condition, perhaps because of anatomical variation.

여성 외음부에 발생한 배아형 횡문근육종

최성관(Sung Koan Choi),성기영(Gi Young Seong),김도원(Do Won Kim),정상립(Sang Lip Chung) 대한피부과학회 1988 대한피부과학회지 Vol.26 No.6

We report a case of embryonal rhabdomyosarcoma with palpable right inguinal lymph node in a 6-year-old girl which developed rapidly on the right labia minora over a period of 2 montha. Histopathological study showed characteristic findings of spindle shaped rhabdomyoblast with hyperchromatic nuclei and cytoplasmicprocesses. After a preoperative chemotherapy with vincristine, actinomycin D, and cytoxan, the size of the mass was reduced, and lymph nodes were not palpable. And then, simple vulvectomy. postoperhtive cheirnatherapy and radiotherapy were done,

소아에서 발생한 장기 융기성 홍반

최성관(Sung Koan Choi),정상립(Sang Lip Chung),김성화(Sung Hwa Kim),서순봉(Soon Bong Suh) 대한피부과학회 1989 대한피부과학회지 Vol.27 No.1

We report a case of erythema elevatum ditinum in a 6-year-old girl. Th symmetrically distributed skin lesions consisted of elevated purplish annular plaques and nodules on the elbows, knees, ankles and buttocks, and some of the lesions showed vesicles, hemorrhagic crusts, and necroses. Biopsy specimens from the knee and ankle revealed typical leukocytoclastic vasculitis. Ve performed a Multites CMI, a test for delayed r.utaneous hypersensitivity, in which the patient showed positive reaction to streptococcal antigen(Lancefield group C). We tried oral prednisolone and dapsone seperately and could see a remarkable response to both drugs.

대뇌상 진피내 모반에 의한 뇌 회상 피부

나건연(Gun Yeon Na),최성관(Sung Koan Choi),정상립(Sang Lip Chung),전재복(Jae Bok Jun) 대한피부과학회 1987 대한피부과학회지 Vol.25 No.5

Cutis verticis gyrata is a morphologic term, typically occurring on the scalp, characterized by eleuated, folded convolutions of the scalp, which may be either secondary to local disease in the scalp, or primary(idiopathic) disease. This case report was a 33-year-old woman, teacher. A birth, the patient had a small, round, soft, convoluted mass on the right parietal scalp. The mass slowly enlarged in size with the same rate of body growth. Now, the lesion is 15*13cm in size, well demarcated, oval shaped, soft, convoluted mass with overlying normal skin colored or hyperpigmented macules. Light rnicroscopic findings of the skin kesion showed deeper extension of the nevus cells into the dermis and subcutis, which presented as an intradermal nevus, Electron microscopy showed that the nevus cell had an indented nucleus and numerous mitochondrias and melanosomes in the cytoplasm.

어린이에서 발생한 모낭충증

정경재(Kyung Jae Chung),최성관(Sung Koan Choi),김도원(Do Won Kim),서순봉(Soon Bong Suh) 대한피부과학회 1988 대한피부과학회지 Vol.26 No.3

We herein report a case a demodicidosis, which is extremely rare in early childhood, in a 19 month old boy. He had been admitted to the department of plastic surgery for 20 days because of burn on both legs. During admission, he hadn't had his face washed at all. He was referred to our department due to progressively appearing, multiple, pinhead sized, dry scaling, erythematous papules on the face of 13 days duration. KOH mounts from the scaly papules revealed numerous hair follicule mites. We treated him with topical application of 25% benzoy1 peroxide gel to see complete clearing of the lesions in 32 days. We think that prolonged ret.ention of sebum in the unwashed skin, such as in our case, may predispose to the poliferation of the hair follicule mites.

Trichophyton tonsurans에 의한 Black Dot Ringworm

서순봉 ( Soon Bong Suh ),김성화 ( Sung Wha Kim ),오수희 ( Soo Hee Oh ),최성관 ( Sung Koan Choi ),방용준 ( Young Jun Bang ) 대한피부과학회 1998 대한피부과학회지 Vol.36 No.5

Trichophyton tonsurans is a major causative agent of tinea capitis in the United States, Canada, Mezico and other Latin American countries, but the infection of T.tonsurans has not been reported in Korea. We report a case of tinea capitis caused by T. tonsurans in a 15-year-old student wrestler. He had a 3*3cm sized non-inflammatory alopecia with black dots on the right occipital area of the scalp. The diagnosis was established by a hght microscopic examination of the affected hairs and by mycological studies from cultures. To our knowledge, this is the first case in which T. tonsurans has been isolated in Korea, It is likely that the student acquired the infection through contact with a foreign wrestler during interaational games and practice. We should be concerned about the potential of spread of this infection in our country. (Korean J Dermatol 1998;36(5): 918-923)

Trichophyton tonsurans에 의한 두부 독창 3예

최성관,이영헌,오수희,김성화,방용준,서순봉 대한의진균학회 1998 대한의진균학회지 Vol.3 No.2

We report three cases of kerion celsi caused by Trichophyton tonsurans in 16-year-old students of one high school wrestling team. The first case presented a 10×15cm and several 3~4cm sized, markedly inflammatory, boggy lesions on the scalp for 5 months. Other cases showed several 2~4cm sized, erythematous, follicular pustules and nodules with partial alopecia on the scalp for 2months. Histopathology and results of mycologic study were consistent with kerion celsi due to Trichophyton tonsurans. All lesions were successfully treated with griseofulvin 500mg daily for 7~15weeks and short term therapy of low dose of prednisolone and cephadroxil.

최근 10년간 Microsporum canis의 감염 상태(1983-1992)

최성관,오수희,김성화,서순봉 대한의진균학회 1996 대한의진균학회지 Vol.1 No.1

ackground: Microsporum(M) canis infection was first discovered in 1957 in Korea, but it did not spread and disappeared after 1960. It was discovered again in 1975, and rapidly spread all over the country. In the 1980's, M. canis became one of the most important dermatophytes that infected humans. Objective: The purpose of this study is to evaluate the clinical and epidemiological characteristics of M. canis infections. Methods: We observed the clinical and epidemiological status in 2,256 cases of M. canis infections that were mycologically diagnosed at the Catholic Skin Disease Clinic from 1983 to 1992. Results: The rate of M. canis infections compared to total dermatophytoses(25,907 patients) was 8.7%. The annual number of patients with M. canis infection increased gradually from 1983 and was highest frequency in 1986. Then the number of patients with M. canis infection was markedly decreased till 1992. The ratio of male to female patients was 0.85: 1(male:1,039,female:1,217), but the ratio in children (age≤ 15) was 1.02: 1 and in adults(age≥16) was 0.33: 1. Children were chiefly involved as 82.6% of the patients. There were more patients in winter(35.3%)and followed by fall, summer and spring. M. canis infections were mostly composed of tinea(T.) capitis(64.2%), T.faciale(17.7%) and T. corporis(14.6%). In the seasonal distribution of M. canis infections, T. capitis was the most common in winter(38.8%) and was the lowest in summer(15.4%),but T. corporis was the most common in summer(42%). There was a difference in disease pattern between children and adults in M. canis infections; In children, M. canis infections were T. capitis(73.6%), T. faciale(16.3%), T. corporis(9%), but in adults, those were T. corporis(41.3%), T. faciale(24.5%), T, capitis(19.4%) in the order of decreasing frequency. Conclusion: We observed a gradual decrease in number of patient with M. canis infection after 1986. We suggest that M. canis infections would decrease more and more in the future in Korea.

서울의 PPNG 발생빈도(1988)

김재홍,이정욱,소순남,김영태,김중환,한영수,이성열,김동석,이봉구,이상수,윤종성,임이석,이종성,김호준,최성관,이성배,강성범,조규종,안철현,차영수,전환표,이주흥 대한화학요법학회 1989 대한화학요법학회지 Vol.7 No.2

The prevalence of PPNG among pretreatment isolates at a STD clinic in Seoul has been studied and reported annually since 1981. In 1988, 461 strains of N. gonorrhoeae were isolated, among which 258 (56.0%) were PPNGs. The prevalence of PPNG in Seoul is still increasing.