제41차 추계학술대회 : 본 연제 ; 피부 병리학, 면역조직화학 : 유방외 Paget병의 Keratin, CEA, Involucrin에 대한 면역 조직화학적 연구

차영수,황규왕 대한피부과학회 1989 초록집 Vol.27 No.50

1996년도 제35차 대한소화기학회 추계학술대회 / 일반연제 : 간 ; 만성 B 형 간염환자의 간조직에서의 Fas 항원 발현

차영수,홍성표,박성곤,원욱희,김배영,박필원,임규성,최윤정,안희정 ( Y . S . Cha,S . P . Hong,S . G . Park,W . H . Won,B . Y . Kim,P . W . Park,G . S . Rim,Y . J . Choi,H . J . Ahn ) 대한소화기학회 1996 대한소화기학회지 Vol.28 No.1

출산전후의 요오드 섭취량과 산후 갑상선염과의 상관관계에 대한 임상적 고찰

차영수,조용욱,국진환,박필원,강명서,이위현,김유리,임정은,조여원 대한내분비학회 1997 Endocrinology and metabolism Vol.12 No.4

Background: Excessive iodine intake increases the occurrence of autoimmune thyroid disorders by enhancing immunogenecity of iodine-rich thyroglobulin, In Korea, most of postpartum women take a large amount of iodine-rich seaweed. Although the excessive iodine intake may affect the thyroid function, only a few reports were available concering iodine intake, especially on postpartum period. Methods: A prospective study was undertaken in 146 of normal delivered postpartum women. Dietary intake and urinary excretion of iodine, serum T3, T4, TSH, anti-TPO Ab and anti-Tg Ab were measured before and 1, 6, 12 and 24 weeks after delivery. Iodine intake was analyzed by one-to-one interview using 24hr recall and food frequency questionnaire. Results: 1. PPT was occurred in 6(10.3%) postparturn women, It presented as hypothyroidism alone in 1(16.7%), transient thyrotoxicosis followed by hypothyroidisrn in 3(50.0%), and thyrotoxicosis alone in 2(33.3%) of the follwed-up patients. 2. During pregnancy, no difference was found in age, serum T3, T4 and TSH between PPT and normal thyroid function group. 3. In PPT group, anti-TPO and anti-Tg Ab were significantly higher than those of normal thyroid function group during pregnancy, and their sensitivity for PPT was 40% and 33%, respectively. But there was no correlation between dietary iodine intake and the titer of thyroid auto-antibodies. 4. There was no correlation between pre and post-partum dietary iodine intake and occurrence of PPT. Conclusion: In Korea, the incidence of PPT was slightly higher than other nations. The sensitivity of thyroid auto-antibodies was too low to use for prediction of PPT. Pre and post-partum iodine intake had no effect on the occurrence of PPT and post-partum thyroid function. (J Korean Soc Endocrinol 12:541-549, 1997)

Combined traning이 멀리뛰기 기록향상에 대한 연구

車瑛洙 중앙대학교 교육대학원 1992 교육논총 Vol.9 No.1

제 50 차 대한내과학회 추계학술대회 초록집 : 당뇨병환자의 복합뇌하수체 자극시험

차영수,조용욱,양인명,박철영,오승준,우정택,김성운,김진우,김영설,최영길 대한내과학회 1998 대한내과학회 추계학술대회 Vol.55 No.-

재생골재를 사용한 콘크리트의 강도특성에 관한 연구

차영수,김희성 동의공업대학 2000 論文集 Vol.26 No.1

Recycling the demolished concrete as the aggregate for concrete is an important and urgent subject in the side of not only the application of waste materials but also the security of aggregate resources. This can contribute to the solution of two problems. The first is the shortage of aggregate from river, and the second is the waste disposal problem. Recently, recycled aggregate has been used in low-grade materials such as subbase layer of the road construction. It is the purpose of this study that the practical use of recycled fine and coarse aggregates for high-grade material such as structural aggregate. Several cases were selected for testing whether this is suitable or not. From outcome of these experiments, it was found physical and chemical properties of recycled aggregates. Therefore, the purpose of this study is to analyze the applicability of recycled concrete in the influence of a substitute rate of recycled fine and coarse aggregates.

새롭게 진단된 제2형 당뇨병 환자에서의 좌심실 이완기 기능 장애

차영수,최홍엽,박진경,이준,임상욱,차동훈,홍은경,박석원,김유리,조용욱,이상종 대한내과학회 2002 대한내과학회지 Vol.62 No.4

Background : Heart failure is one of the major cause of premature mortality and morbidity in diabetes mellitus. It has been well recognized that left ventricular diastolic dysfunction caused by autonomic neuropathy, hyperinsulinemia, hyperlipidemia might be a preceding underlying mechanism of heart failure in diabetes. Also, an impairment of diastolic function in early diabetic patients has been reported in some literature. So, we evaluated the diastolic function in newly diagnosed diabetics with echocardiography. Methods : All patients with newly diagnosed NIDDM in Pundang Cha general hospital from December 1996 to June 1998 were enrolled (n=20). The 20 healthy volunteers comparable for age, sex, body surface area were enrolled as a control group. The echocardiography was performed in all patients before any treatment. Blood pressure, pulse rate, fasting and postprandial sugar and insulin level, serum total cholesterol, triglyceride, HDL-cholesterol, LDL-cholesterol were also checked in all patients. Results : There were no significant difference in blood pressure, pulse rate, total cholesterol, triglyceride, HDL-cholesterol and LDL-cholesterol level between both groups. E and A ratio of mitral inflow and peak diastolic velocity of pulmonary vein flow were significantly decreased in NIDDM group compared with control group (p<0.01). But there were no significant difference in left ventricular mass index, isovolumic relaxation time, deceleration time and peak atrial reversal velocity. Conclusion : This study demonstrates that an impairment of left ventricular diastolic function occurs early in the NIDDM and investigation of diastolic function should be performed in the clinical evaluation of early diabetic patients.(Korean J Med 62:422-429, 2002) 목적 : 심부전증은 당뇨병 환자에서의 중요한 사망 원인이며 자율신경병증, 고인슐린 혈증, 고지방 혈증 등에 의해 유발될 수 있는 좌심실 이완기 기능 장애는 심부전증의 위험 요인으로 알려져 있다. 또한 유병 기간이 1년 이내인 제2형 당뇨병 환자에서도 이러한 변화가 있다는 보고가 있다. 이에 저자들은 처음 제2형 당뇨병을 진단 받은 환자를 대상으로 심초음파를 시행하여 좌심실 이완기 기능 장애 여부를 평가하였다. 방법 : 1996년 12월부터 1998년 6월까지 분당 차병원에 내원하여 처음으로 제2형 당뇨병을 진단 받은 환자들을 대상으로 하였다 (n=20, 당뇨병 환자군). 대상 환자들은 어떠한 치료도 받지 않은 상태에서 심초음파를 시행하였다. 대조군은 분당 차병원 건강 검진에 내원한 환자 중 아무런 질환이 없는 20명의 환자를 대상으로 하여 당뇨병 환자군과 같은 방법으로 심초음파를 시행하였다. 모든 대상 환자들의 혈압, 심박수, 혈중 콜레스테롤, 중성지방, 고밀도 지단백, 저밀도 지단백을 측정하였다. 결과 : 연령, 혈압, 심박수, 혈중 콜레스테롤, 중성지방, 고밀도 지단백, 저밀도 지단백 등의 임상적 특징은 양군간에 유의한 차이를 보이지 않았다. 심초음파 검사 결과에서 심구혈율, 좌심실 질량 지표, 좌심실 이완기말 직경도 양군간에 유의한 차이를 보이지 않았다. 그러나 E/A ratio는 당뇨병 환자군에서 1.06±0.28로 대조군의 1.60±0.27에 비해 유의하게 감소되어 있었으며 (p<0.01) 등용성 이완 시간도 당뇨병 환자군과 대조군이 각각 90.8±18.7 ms, 75.0±15.2 ms로 당뇨병 환자군에서 유의하게 증가되어 있었다 (p<0.01). 마지막으로 감속 기간은 양군간에 유의한 차이를 보이지 않았다.

基礎體力 育成이 멀리뛰기 記錄向上에 미치는 影響

車瑛洙,李潤根 중앙대학교 스포츠과학연구소 1994 體育硏究 Vol.- No.7

The study has showed that the basic physical strength is essential to the improvement on long Jump thus, this study is performend that aim of improving the function of Athletic and makes strengthen of high school student's physical fitness. It performed training devided by two group that named the experimental Group and Comperative one. After training, we measured and analyzed two group about items as Sargent jump, shuttle run, sit up, 100M run, standing long jump. We got conclusions as follow; 1. As a result of the performing for designed reinforced exercise, the record improving on long jump, is noticable (the value of C.R=5.48) 2. As a result of measuring the basic physical fitness after training, then are noticable improvement an Sargent jump and 100M run and standing long jump, and the value of C.R on shuttle run and sit up are has not a meaning. but the aspect of recores improvement is noticable. Therefor It shows important of reinforce exercise because of the basic physical fitness achieve through general reinforce exercise.

5년간 집단 검진에 의한 연취급 사업장 근로자들의 건강수준 평가

차영수,이성수,안규동,한구웅,이병국 순천향 대학교 산업의학연구소 출판부 1995 순천향산업의학 Vol.1 No.1

To evaluate the health status of workers in lead using industries under supervision by Soonchunhyang University Institute of Industrial Medicine as part of program of group occupational health service and find out longitudinal changes of health status of lead workers through the service for 5 years from 1989 to 1993, authors analyzed 5 years's periodic health examination data which comprised 29 lead using industries with 40,035 total cumulative number of workers. Selected variables for this study were screening results of general health examination and final results of confirmative health examination for the general health examination which dealt with office workers and blue collar workers with no exposure of hazardous condition. For the special health examination, zinc protoporphyrin in whole blood (ZPP) and screening results of special health examination were selected for study variables. For the confirmative special health examination with screening positive workers, blood lead(PbB), delta-aminolevulinic acid in urine, ZPP, and final result were selected for study variables. Information on age, sex, and type of industries were also collected. The results obtained were as follows; 1. The five years screening positive rate for general health examination was 13.7% and 5 years rate for C category which did not need further confirmative recheck was 5.2%. 2. While the proportion of liver disease in C category in primary general health examination was 49.2% those of anemic disease and hypertensive disease were 23.3% and 27.5% respectively. 3. Five years screening positive rate and negative rate for storage battery industries, secondary smelting related industries, telecommunication related industries and other industries were 83.4% and 12.4 %, 76.5% and 17.5%, 75.5% and16.4%, and 79.5 and 14.4% respectively. 4. Screening positive rate for 5 years were increased as age increased from 9.0%(age less than 30 years ) to 21.1% (age more than 40 years). 5. Only 22.1% of screening positive workers for 5 years general health examination were diagnosed as confirmed general diseases and 33.1% were revealed as normal. The rate of confirmed general diseases were differed by the type of industries and they were increased by age increased. 6. The rate confirmed general disease and non-disease in screening positive of liver, cardiovascular, tuberculosis and chest, anemic and renal disease category were 25.5% & 14,5%, 22.8% &37.2% 21.5% &23.0% 62.0% & 7.0%, and 16.5% & 53.9% respectively. 7. The 5 years prevalence rate of confirmed general disease(D_(2)/total workers) and prevalence rate of abnormal finding(C+D_(2)) were 3.21% and 14.9% as a whole. By the screened disease category, those rate were 1.23% &6.89% for liver disease, 1.17% & 5.43% for cardiovascular disease, 0.96% &1.64% for tuberculosis and chest disease, 0.76% & 1.02% for anemic disease and 0.03% & 0.06% for renal disease respectively. 8. The five years screening positive rate of all lead workers with the criteria of the measurement of ZPP(>=100㎍/㎗) was 10.2% (female lead workers :25.5% male lead workers :8.1%). The positive rate has tendency to decrease year by year from 1989 to 1993. The phenomenon of decrease of rate was significant in storage battery industries, but not apparent in secondary smelting related industries. 9. The proportion of lead poisoning (D_(1)) among screening positive of lead workers was 14.9% for 5 year special health examination and rest of screening positive were diagnosed as high lead absorption. White the proportion of D_(1) was 8.8% in storage battery industries, that was 23.9% in secondary smelting related industries. 10. The distribution of screening positive lead workers by the group of ZPP for 5 years as a whole was 48.3%, 20.9%, 20.5% and 10.3% in the group of ZPP 100-149㎍/㎗, 150-199㎍/㎗, 200-299㎍/㎗ and above 300㎍/㎗, respectively. 11. The proportion of screening positive lead workers whose blood lead were above 60㎍/㎗ and whose urine ALA were above 10㎎/ℓ were 53.3% and 61.4%, respectively. 12. The 5 year overall prevalence rate of lead poisoning (D_(1)/all lead workers) was 0.142%(female lead workers:0.116%, male lead workers:0.145). For the rate of high lead absorption((C+D_(1))/all lead workers) was 0.945%(female lead workers:2.36, male lead workers :0.756). The above prevalence was decreased in later year of study period than early year of study period.

만성 B형 간염환자의 간조직에서의 Fas 항원의 발현

차영수,홍성표,최윤정,국진환,최유정,김경철,김배영,박필원,임규성 大韓消化器病學會 1998 大韓消化器病學會誌 Vol.31 No.2