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桑白皮가 白鼠 腹腔 肥滿細胞에 미치는 影響에 關한 細胞形態學的 硏究
蘇淳南,金禎洙,田炳得,李武三 전북대학교 의과학연구소 1986 全北醫大論文集 Vol.10 No.3
In order to investigate the cytomorphological influences of Cortex Mori on the rat peritoneal mast cells, this study was performed. After the rat peritoneal mast cell are suspended, the following results were obtained ; 1. Within 5 minutes after the addition of compound 38/80 solution(20μg/ml). degranulation of mast cells were induced. 2. Within 30 minutes after the addition of Cortex Mori solution (1mg/ml), degranulation of mast cell was induced. 3. The pretreated mast cells with Cortex Mori solution for 3 minutes did not show degranulation within 30 minutes after the addition of compound 48/80. 4. Within 30 minutes after the addition of solution of which pH and osmolarity equal to those of Cortex Mori solution, degranulation of mast cells was not induced. 5. The mast cells pretreated with solution of which pH and osmolarity equal to those of Cortex Mori solution for 3 minutes, show degranulation within 3 minutes after the addition of compound 48/80 solution. From the above results, it is suggested that the Cortex Mori may have some substances to inhibit the compound 48/80 dependant degranulation of the mast cell although it was not known how Cortex Mori acts on the mast cell. (Key words : Cortex Mori, mast cell)
김중환,김재홍,김영태,소순남 대한감염학회 1988 감염 Vol.20 No.4
Secondary syphilis is a great immitator. When syphilis produce unusual skin lesions, the diagnosis is often difficult and delayed. We report a case of secondary nodular syphilis with features of cutaneous lymphoma. A 52-year-old male patient has had erythematous to brownish nodules with pruritis and generalized lymphadenopathy for about 5 weeks prior to visit to our clinc. The diagnosis was eventually made by a skin biopsy and serologic tests for syphilis. Histopathologically, numerous plasma cells around blood vessles and endothelial hyperplasia were ween in the dermis and Warthin-Starry stain shows Treponema pallidum. Serologic tests revealed that VDRL was reactive at 1:64 dilutions and TPHA was reactive.
소순남(Soon Nam Soh),김중환(Joong Hwan Kim),김영태(Young Tae Kim),김재홍(Jae Hong Kim) 대한피부과학회 1990 大韓皮膚科學會誌 Vol.28 No.1
An important concern in treatment for gonorrhea is the high frequency of coexisting chlarnydial and gonococcal infections. But there is difficulty in the diagnosing chlamydial infection. And so, CDC recommends epidemiological treatment, of both gonorrhea and non-gonococcal urethritis in the gonorrheal treatment in order to prevent post-gonococcal urethritis(PGU), A total of 140 male patients with uncomplicated gonococcal urethritis at the VD clinic, Choong-ku Publir. Health Center, in Seoul during December, 1987 February, 1988 were subjected to this study. The patients treated with kanamycin(KM), 2g and aqueous penicillin G(ACPG) 8 million units imaccompanied by probenecid(BEN) 1g by mouth. This combination regimen showed good effect in the treatment of gonococcal urethritis (failure rate 4.2% ). After gonorrheal treatment, the patients were divided randomly into group A and group B. In the group A, adminstrated with doxycycline monohydrate, 100mg, by mouth two times daily for 7 days, 44 and 29 patients were followed at 7th and 14th day after gonorrheal treatment. In the group B, administrated with placebo, 1 tablet, by mouth two times daily for 7 days, 49 and 39 patients were followed at 7th and 14th day after gonorrheal treatment. The PGU incidences were 27.3%(12/44), 20.7%(6,'29) in the group A and 55. 1%(27,'49), 53.8(21/39) in the group B at 7th and 14th day after gonorrheal treatment. Conclusively, eoncornitant administration of doxycycline monohydrate, 100mg, by mouth two times daily for 7 days with gonorrheal treatment lowered PGU significantly. (Kor J Dermatol 28(l): 34 38, 1990)