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간경변증 환자에서 혈청 4형 Collagen-7S의 의의
차경석(Kyoung Seok Cha),한영찬(Young Chan Han),김영태(Young Tae Kim),이숭구(Sung Ku Lee),서대원(Dae Won Seo),김영중(Young Jung Kim),박병익(Beong Yik Park),조민구(Min Koo Cho) 대한소화기학회 1995 대한소화기학회지 Vol.27 No.3
N/A Background/Aims: Cirrhosis is defined anatomically as a diffuse process with fibrosis and nodule formation. Although liver biopsy provides the evaluation of the degree of fibrosis, a simpler diagnostic method would be helpful for its invasive nature. The serum type IV collagen is known recently to indicate the activity of collagen synthesis in the process of fibrosis. This study aims to evaluate the usefulness of serum type IV collagen with the clinical and laboratory findings. Methods: A number of abnormalities were found to be statistically associated with the levels of serum type IV collagen. Included among the clinical abnormalities were pitting edema, ascites, splenomegaly, jaundice, and encephalopathy. The laboratory tests include albumin, tota1 bilirubin, prothrombin time, and alkaline phosphatase. Results: Significant correlations were found between the serum type IV collagen and the grade of the modified Childs classification(p0.05: between class A and B, class B and C, respectively), as well as the CCLI(comhined clinical and laboratory index, r=0.74, Y=6.78 +0.71X, p0.001). Conclusions: These results suggest that the serum type IV collagen may be a sensitive marker of fibrotic process and may reflect the present state and prognosis in cirrhosis. (Korean J Gastroenterol 1995;27:331 337)
김영중,차주영,윤수진,조민구,김소연,이권전,김윤권,시석,전종구,오형모,장원규,박병익 대한소화기학회 2000 대한소화기학회지 Vol.36 No.4
The chylous ascites is a rare disease characterized by accumulation of chylomicron in the ascitic fluid. The chylous ascites developed naturally in liver cirrhosis accounts for approximately 0.5 % of liver cirrhosis with ascites and shows poor prognosis. This report presents a case of chylous ascites accompanied by liver cirrhosis.
삼배체 염색체 이상을 보인 급성 림프구성 백혈병 1 예
이은희,김영중,차주영,이경인,박병익,김윤권,조민구,김소연,이권전,오형모,전종구,신요식 대한내과학회 2001 대한내과학회지 Vol.61 No.2
$quot;In addition to age, white cell count and immunophenotype, karyotype has been reported to be one of the important prognostic factors in acute lymphocytic leukemias. Furthermore 70 percent of patients with acute B lymphocytic leukemia presented chromosomal abnormalities, which is known to have a close relationship with the prognosis. Among the abnormalities, triploid is rare and known to have the worse prognosis. Structural chromosomal abnormality of the 11q23 band is more common in childhood acute lymphocytic leukemia and has been rarely reported in adult lymphocytic leukemia. We present a case of a 29 year - old male patient with acute lymphocytic leukemia, who had triploid and chromosomal translocation including 11q23 band along with the review of related literature.(Korean J Med 61:190-194, 2001)$quot;
김영중,유광현,김용일,이윤하,김소연,황인섭,차경석,최병진,조민구 대한내과학회 1996 대한내과학회지 Vol.50 No.3
Focal nodular hyperplasia(FNH) is a rare benign hepatic tumor usually discovered serendipitous]y by an imaging procedure performed for some other reason. FNH is typically asymptomatic, and invariably follows a benign course. Accordingly, the preferred management is conservative, and excision is reserved for large symptomatic and complicated lesion, or when the diagnosis remains uncertain. Although many cases of FNH has been described to date in other countries, only two cases of FNH has been reported in Korean literature. But biopsy proven case have not been reported in Korea. In the present report we describe a 15 cm sized symptomatic lesion of FNH in a 29-year-old woman, that was disclosed by various kinds of imaging procedure. A left lateral segmentectomy was performed. The mass was firm and showed areas of localized growth of mature hepatocytes and septal fibrosis accompanied with marginal ductal proliferation, consistent with FNH. It also displayed an incomplete stellate architectural configuration consisted of a central fibrous scar. We report a case of FNH with a review of the literature.