http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : 정정명 ( Jung Myung Jung ) (검색결과 101 건)
- 무료
- 기관 내 무료
- 유료
-
-
정정명 ( Jung Myung Chung ),설상훈 ( Sang Hoon Seol ),이상봉 ( Sang Bong Lee ),설상영 ( Sang Young Seol ),윤혜경 ( Hye Kyung Yoon ) 대한소화기학회 2003 대한소화기학회지 Vol.41 No.2
Backgrounds/Aims: We aimed to confirm the possibility of the development of stomach cancer by Helicobacter pylori (H. pylori) infection and chronic gastritis with intestinal metaplasia. Methods: The study group consisted of 16 patients with stomach cancer
-
정정명(Jung Myung Chung),정해철(Hae Chul Chng),설상영(Sang Yeong Seol),정승진(Seung Jin Jeong),최석렬(Seok Reyol Choi),최하진(Ha Chin Choe) 대한소화기학회 1985 대한소화기학회지 Vol.17 No.1
N/A Although several classifications of esophageal varices are reported at present monent, none of them seems to be perfect in terms of clinical applicability. Some are too simple to cover the whole features of varices, or too much complicated to apply practically to clinical practices. Recent remarkable advances of endoscopy has let more precise serial observations and prognostic evaluation of varices be possible without great difficulties. Having observed 373 cases of esophageal varices from Jan. 1981 to June. 1984 at Paik Hospital, In-Je Medical College, we have tried a new classification of esophageal varices, according to not only their shape, size, numbers, colors and locations, but having particular consideration on their bleeding episodes. Endoscopic grades of esophageal varices are classified into following 4 grades, Grade I: One or two tiny tortuous, blue colored varices, less than 2 mm in diameter, being localized in lower esophagus. Grade II: Bead-like tortuosity, blue colored varices, mostly 2-4 mm in diameter being localized in lower esophagus. Grade III: Varices on the top of the varices, red colored, mostly more than 4 mm in diameter with spreading up to mid esophagus. Grade IV: Grade III varices with spreading through the entire esophagus and or down to the fundus of stomach. Bleeding tendency was most frequently observed in Grade IV varices.
-
위 십이지장질환 환자들의 위액내 Fungus 에 관한 연구
정정명(Jung Myung Chung),박주열(Joo Youl Park),문기석(Key Seack Moon),김병제(Byoung Je Kim),김동민(Dong Min Kim),최하진(Ha Jin Choi) 대한내과학회 1986 대한내과학회지 Vol.31 No.1
N/A It is widely known that with recent environmental changes and improved methods of diagnosis, infection of fungi in a number of human organ is steadily increasing. Despite a few reports made by scientists on the relationship between candida infection and gastroenteric diseases, the infection and growth of fungi in a stomach and gastric juices has been seldom reported. In cases of gastric and duodenal disease, however, enviornmental changes within a stomach such as changes of gastric juices, disturbances of gastric motility and impairment of gastric mucosa are likely to come about, it can, therefore, be assumed that the growth of various fungi in a stomach and gastric juices is possible. Recently we have investigated the fungal infection in gastric juices aspirated from various gastroduodenal disease patients and obtained following results. 1) 40 patients have vague epigastric pain complaints for a long duration, although no definite pathological findings are endoscopically recognizable in stomach and duodenum, 16 duodenal ulcer patients, 30 gastric ulcer patients and 30 stomach cancer patients were studied on fungal growth in their salivas and gastric juices aspirated from their mouth and stomach. 2) pH of gastric juices from 21 patients in whom fungus was grown in their stomach aspirates was 4.85±1.45, whereas pH of gastric juices from another 21 patients in whom no fungus was grown was 1.91±0.61. A rather striking difference in their acidity between those 2 groups is recognizable, as already reported previously, 3) The frequency of fungal growth in gastric juices was found in following order. 32.5% of cases of non-ulcer, non-cancer patients, 18.8% of cases of duodenal ulcer patients, 73.3% of cases of gastric ulcer patients, and 83.3% of cases of stomach cancer patients. Among those patients who have fungal growth in their gastric juice, candida was found. 25.0% of cases of non-ulcer, non-cancer patients 6.3% of cases of duodenal ulcer patients, 60.0% of cases of gastric ulcer patients, and 70.0% of cases of stomach cancer patients. It was revealed that the frequency was rather higher in gastric ulcer and stomach cancer patients than in duodenal ulcer and non-ulcer, non-cancer patients. 4) Ten non-ulcer, non-cancer patients who had fungal growth in their gastric aspirates were, 6 cases of acute gastroenteritis, 2 cases of cirrhosis, 1 case of Parkinson's disease, and 1 case of renal stone.
-
식도 정맥류 출혈에 대한 내시경적 경화요법의 장기 관찰 결과
정정명(Jung Myung Chung),최하진(Ha Jin Choi),윤중근(Jung Kun Yoon),김병제(Byoung Jae Kim),박경태(Kyung Tae Park),김상정(Sang Jeong Kim) 대한소화기학회 1987 대한소화기학회지 Vol.19 No.1
N/A Esophageal Varices Bleeding is one of the major causes of death among the patients with liver cirrhosis or portal hypertenison, and it represents,50% mortality each episode of bleeding. As the method for the treatment of Esophageal Varices Bleeding, supportive cares such as Balloon tamponade, infusion of vasopressin are usually practiced but the results of therapy have been found unsatisfactory. Although surgical therapy can also be expected to improve the one-year survival rate, its long-term survival rate is very low because of high incidence of morbidity. For the purpose of improving these therapeutic defects, Endoscopic Injection Sclerotherapy has been tried as a new method and its good effects have been reported recently. Endoscopic Injection Sclerotherapy is so effective on the emergency treatment of Esophageal Varices Bleeding. However, it gives rise to many debates on the improvement of long-term survival rate. To investigate long-term prognosis of Endoscopic Injection Sclerotherapy, we evaluated the survival rates and the therapeutic effects on 150 patients with Esophageal Varices Bleeding, who were treated by Endoscopic Injection Sclerotherapv and could be followed up by the Department of Internal Medicine, In-Je Medical College. The results are as follow;. 1) Rebleeding occurred in,53 cases(35.3%) among patients followed up over one month after the first Endoscopic Injection Sclerotherapy. The incidence of rebleeding was highest within 6 months, noted in 23 cases (15.3%) which were 43.3% of all rebleedings. 2) Major complications of Injection Sclerotherapy were 6 cases of aspiration pneumonia. 4 cases of esophageal ulcer, 3 cases of esophageal stenosis, and of mediastinitis.Among all 16 cases fatal complications were estimated in cases. 3)During the follow up-period, 66 cases (44.0%) were expired. 26 cases (17.3%), which were 39.4% of all mortality, of expired cases were within one month after Sclerotherapy. The causes of their deaths were of hepatic failure in 35 cases(23.3%), of hepatoma in 16 cases (10.7%). of uncontrolled bleeding in 13 cases (8.7%), and of complications in 2 cases (1.3%). 4) The one-year survival rate of the patient afteer Sclerotherapy was 70.0%, and the four-years survival rate 40.0% (8 cases of 20 cases were survived). The survival rate of those patients was concerned with Child's Classicfication and remarkeable reduction in survival rate was noted in Child's class C. As the preceeding results, it isconsidered to be obvious that Endoscopic Injection Sclerotherapy is a recommendable method for the treatment and Esophageal Varices Bleeding. However, still high frequency of rebleeding and Hospital mortality are considered as projects to be improved hereafter.
-
-
위 십이지장 질환들의 위액내 Bile Acid 와 Lysolecithin 농도에 관한 관찰
정정명(Jung Myung Chung),정봉균(Bong Kun Jeon),김수찬(Soo Chan Kim),주영돈(Young Don Joo),설상영(Sang Young Soel),최하진(Ha Jin Choi) 대한내과학회 1989 대한내과학회지 Vol.37 No.3
N/A A peptic ulcer is a benign ulcerative lesion in the alimentary tract developed by corrosive and digestive action of acid and pepsin in gastric juice and its cause is thought to be due to the imbalance of aggressive factors and defense mechanisms in gastric juice. But there are many controversies about the etiologic factors of peptic ulcer and further studies are needed for understanding of the pathophysiologic mechanisms. Recently it has been reported that bile and pancreatic juice could be refluxed into the upper duodenum or stomach under certain conditions, so gastric and duodenal ulcers could be induced by those digestive actions. This reflux phenomenon is supposed to be an important etiologic factor of gastric ulcer. More specifically, bile acid and lysolecithin of the refluxed duodenal contents increase back diffusion of hydrogen ions in the stomach and this back diffusion of hydrogen ions could induce acute or chronic gastritis and gastric ulcer. Moreover, it is carefully presumed that this reflux-induced acute and chronic gastritis acts as a factor of non-ulcer dyspepsia, and chronic stimulation of refluxed bile acid and lysolecithin seems likely to be an etiological factor for the development of stump cancer in gastrectomized patients. In this study, we have investigated the levels of bile acid and lysolecithin concentration in gastric juice for the evaluation of some influences of gastroduodena1 reflux on several gastroduodenal diseases. The results were as follows: 1) Bile acid concentration of gastric juice was 46.5±31.0 μmol/l in 13 normal controls, 202.2±109,2 μmol/l in 20 cases of duodenal ulcer, 329.1±101.5 μmol/1 in 28 cases of gastric ulcer 241.8±147.7 μmon/1 in 14 cases of stomach cancer and 352.1±88.7 μmol/1 in 18 cases of non-ulcer dyspepsia. 2) Lysolecithin concentration in gastric juice was 81.0±22.9 μmol/1 in 10 normal controls, 114.3±40.1 μmol/ l in 12 cases of duodenal ulcer, 170.4±43.9 μmol/1 in 10 cases of gastric ulcer, 230.3±172.0 μmol/1 in 6 cases of stomach cancer and 238.9±187.6 μmol/l in 7 cases of non-ulcer dyspepsia. 3) Average bile acid concentration in gastric juice showed a significant increase in each disease group and it was more prominent in gastric diseases including non-ulcer dyspepsia and gastric ulcer than in other groups. 4) Lysolecithin concentration in gastric juice also showed a significant increase in each disease group and it was more prominent in gastric ulcer than in duodenal ulcer. Lysolecithin concentration in the non-ulcer dyspepsia and stomach cancer groups showed a more prominent increase than the control group and duodenal ulcer group but we could not apprehend the clinical significance because the number of cases was negligible. 5) There was no specific correlation between bile acid and lysolecithin concentration of gastric juice in 20 cases of gastric and duodenal ulcers, From our findings, the constant increase of bile acid or lysolecithin concentration in gastric juice might be one of the etiologic factors in development of gastroduodenal diseases, particularly in gastric diseases. However, further study about this problem is thought to be needed.
-
간 질환들에 있어서 HBs 항원 및 HBs 항체 공존예에 관한 관찰
정정명(Jung Myung Chung),최하진(Ha Jin Choi),박경태(Kyung Tae Park),이시억(Si Eok Lee),진지천(Gi Chun Chin),강기상(Ki Sang Kang),설상영(Sang Yung Seol) 대한소화기학회 1988 대한소화기학회지 Vol.20 No.1
N/A A clinica] analysis was made, by enzyme immunoassay, of 64 cases of coexistence of HBs antigen and HBs anti-body in the same serum with the subtype in 12 cases of them being observed. The results were as follows: 1) The overall incidence of coexistence in one period was 1.9% (64/3,395). 2) The highest occurrence rate of coexistence was found in age group of 5th decade: 14 cases (21.9%); in age group of 6th decade: 17 cases (26.6%); and the ratio of male to female was 2.4:l. 3) The diagnostic distributions were 18 cases of liver cirrhosis, 12 cases of hepatoma, 6 cases of chronic active hepatitis, 6 cases of acute viral hepatitis, 7 cases of healthy carrier, and 15 cases were suspected to be chronic hepatitis not confirmed by liver biopsy. 4) In 64 cases of coexistence we studied Hbe antigen and Hbe anti-body in 32 cases. In this study Hbe antigen positive and Hbe antibody negative was found in 18 cases (56.3%); Hbe antigen negative and Hbe antibody positive in 11 cases (34.4%); both Hbe antigen and Hbe antibody vere positive in 1 case (3.1%) and negative in 2 cases (6.2%). 5) The results of subtype were as follows: in 12 cases of HBs antigen positive only, 8 cases were of ay type and the other 4 cases of ay/ad complex type. And in 12 cases of HBs antibody positive onlv, 5 cases v:ere found to be of anti-y type. 5 cases of anti-d type, 1 case of anti-a type and 1 case of anti-y/anti-d complex type. And in 12 cases of HBs antigen and HBs antibody coexistence, ay type antigen were found in 8 cases, and antibody types of these antigen were 8 cases of anti-y type, and 1 case of anti-y/anti-d complex type. In conclusion, although the results of these studies are those of the screening test and have geographic limitation. The coexistance of HBsAg and anti-HBs is considered mostly as a form of seroconversion and rarely as a result of the superinfection with another subtype.
-
-
Candida Albicans 와 Carcinogen 의 경구투여에 의한 Mouse 의 위점막 변화
정정명(Jung Myung Jung),김을수(Eul Soo Kim),오형석(Hyung Seok Oh),최경해(Kyung Hae Choi),이부경(Boo Kyung Lee),설상영(Sang Yung Sul),최하진(Ha Jin Choi) 대한내과학회 1988 대한내과학회지 Vol.34 No.4
N/A 1) In the group of the subject mice administered with candida albicans only, all of 6 mice had an inflammatory change both in stomach antrum and body at the 1 month-interval check. At the 3 month interval check, an inflammation in stomach antrum occurred in all of 6 mice; however, in stomach body 5 mice had an inflammation and 1 mice a mocosal atrophy, At the 6 month-interval check, all of 8 mice had an inflammatory change in stomach antrum, while 4 of them got a mucosal atrophy in stomach body. 2) In the group of the mice with a carcinogen alone administered, 2 of 4 mice in the 6 month-group, and 5 of 8 mice in the 9 month-group revealed a mucosal dysplasia with no appearance of cancer. But the degree of dysplasia was one mouse in grade A and another one mouse in grade B, respectively, at the 6 month-interval check, while 2 mice in grade B, and 3 mice in grade C, respectively, at the 9 month-interval check. 3) In the group of mice administered both with carcinogen and candida albicans, 2 of 4 mice showed no cancer but mucosal dysplasia of grade B at the 6 month-interval check, while at the 9 month-interval check, 6 of 8 mice had a squamous cell cancer (especially 3 having been grossly examined) and the other two had mucosal dysplasia of grade C. 4) The findings in the liver tissue of the mice adminstered with the carcinogen for more than 8 months revealed a severe liver cell dysplasia with no evidence of hepatoma. 5) The results from this experimental study suggested that in case of provoking a stomach cancer due to a carcinogen administered in the mice, gastrointestinal infection of pathogenic organism such as candida does play a promoting role. However, whether a suggestion from this experimental study will be applicable to human beings as well or not will have to await a lot of further researches thereafter in the field, There have been reported many experimental researches on the oncogenic effects of various nitroso-compounds since Barnes and Magee, in 1956, concluded the acute hepatotoxicity and oncogenic action of dimethylnitrosamine in a number of experimental animals. Thereafter these nitroso-compounds have been assumed to be an environmental carcinogen in human beings as well as a potent carcinogen in animals. Much attention has been paid particulary on the relation of stomach cancer and nitrosamine since the nitrosamine synthesis in human gastric juice was known to be available. However. at present, it seems so hard to confirm nitrosamine as a vital factor of human cancer that far more information is demanded to identify it accurately. Recent reports, including ours, show a high frequency of candida albicans infection in gastrointestinal tract by various environmental factors. But the influence of candida multiplication on gastric ulcer or stomach cancer has scarcely been known. In this research we made a study of possible effects of candida infection on the gastric mucosa injury as well as on stomach cancer.
연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
