2세 남아에서 발생한 토착형 삼일열 말라리아 1례

정수진,양윤정,김순기,홍영진,손병관,조병원,정문현,Chung, Soo Jin,Yang, Yun Jung,Kim, Soon Ki,Hong, Young Jin,Son, Byong Kwan,Cho, Byong Won,Chung, Moon Hyun 대한소아감염학회 1997 Pediatric Infection and Vaccine Vol.4 No.2

Malaria, caused by any of four species of protozoan parasites of the genus Plasmodium, is charaterized by high fever, anemia and splenomegaly. Although malaria is a cause of significant morbidity and mortality worldwide, in Korea indigenous malaria has been believed to be eradicated by 1984. However, since the case report of native malaria in 1993, reported cases have been increased annually, reaching more than 300 cases in 1996. We experienced a 2 years-old male with fever, severe anemia and splenomegaly who resided in Inchon city. He had the history of travelling to the area (Yunchon) near western Demilitarized Zone for 1 month this summer. After more than 2 weeks without special attention, he was presented with pallor, anemia and splenomegaly. He was diagnosed to have malaria by Plasmodium vivax with the help of peripheral blood smears which showed various forms of malaria, i.e., ring form, trophozoites, shizonts and gametocytes. He was treated successfully with hydroxychloroquine and primaquine. We report this case with brief review of related literature.

점액 유두상 상의세포종의 압착도말 세포학적 소견 - 1예 보고 -

정수진,양영일,Jung, Soo-Jin,Yang, Young-Il 대한세포병리학회 1999 대한세포병리학회지 Vol.10 No.1

Myxopapillary ependymoma generally arise in the conus medullaris and filum terminale of adult spinal cord. These tumors are readily recognized due to unique histopathologic features, however, their cytologic features are not well described. When only a tiny sample is obtained, cytologic examination using crush preparation may be a useful diagnostic tool to help appropriate intraoperative diagnosis. We present the crush cytologic features of myxopapillary ependymoma arising in thoracic and lumbar spinal cord of a 13-year-old boy. The patient had complained of paraparesis and back pain for 1 month. The MRI image revealed a relatively well demarcated intramedullary mass in T11-L1 levels. Crush preparation for cytology were peformed by biopsy material. Crush cytologic findings revealed high cellularity and small sized branching papillary clusters on fibrillary or mucinous background. The tumor cells had uniform round or elongated nuclei. The cytoplasmic process of tumor cells were attached to the vascular wall. Between the tumor cells and vascular walls, the perivascular collar of globoid acellular stroma with metachromatic reaction on toluidin blue stain was noted. The crush preparation of myxopapillary ependymoma is considered as a simple and highly accurate diagnostic tool for differentiation from other intramedullary neoplasms of central nervous system.

사료내 미량광물질 강화 복합미생물 첨가가 산란노계의 계란생산 및 난질개선에 마치는 영향

정수진,주은정,이우식,윤병선,이주삼,남기택,황성구,Jeong, Soo-Jin,Joo, Eun-Jung,Lee, Woo-Sic,Yon, Byeng-Sun,Lee, Ju-Sam,Nam, Ki-Taek,Hwang, Seong-Gu 한국유기농업학회 2004 韓國有機農業學會誌 Vol.12 No.2

In recent years, the consumption of livestock products were markedly decreased by awareness of world-widely occurred diseases including mad cow disease, Foot and mouth disease, Hog cholera, and Poultry Influenza virus. the consumers ara also wanting to have highly safe food such as organic animal products because of concerning about residual of antibiotics in animal products. However, disease control and impairment of productivity are the major problem in organic animal production. On these points of view, the present study was undertaken to investigate the effects of 1% or 2% of dietary probiotics fortified with various minerals on improvement of egg production and egg quality in old lay6r feeding low quality feed mainly composed of food waste, sesame meal, and rice bran. After 4 weeks of experimental feeding, the diameter of spreading of egg white was clearly decreased from 11.2cm of control eggs to 10.5m and 10.1m in 1% and 2% treatment group eggs, respectively. The color of egg yolk was 9.3 in control eggs but remarkably increased in treatment groups showing 10.1~10.2. Egg production was 75.8% in control layers but significantly increased to 79.8% of 1% treatment group and 82.9% of 2% treatment group layers. Egg weights (C : 66.3g, 1% : 73.2g, and 2% : 76.7g) and egg shell thickness (C : 0.33mm, 1% : 0.35mm and 2% : 0.36mm) were also increased by the addition of 1% or 2% of probiotics when compared to those of control group eggs. All together, it has been suggested that dietary addition of probiotics fortified with various minerals can improve the egg quality and egg production in layer's productivities by the recycling of organic waste resources such as food waste and agricultural by-products.

Statistical considerations in forensic science: a review

정수진,Lee Hyo Jung,이재원 한국통계학회 2021 Journal of the Korean Statistical Society Vol.50 No.3

DNA evidence presented in court is evaluated by calculating its weight. In the case of evidence consisting of two profiles that may be from the same individual, such as a sample of DNA from a crime scene and a sample from a suspect for that crime or the case of one sample from an alleged father and one from the biological father in a paternity case, forensic scientists are must evaluate the weight of evidence. This weight is expressed as a likelihood ratio, or the ratio of the probability that the DNA evidence comes from the alleged father (or suspect) to the probability that it came from another person. In the likelihood ratio, the probability that the evidence would have come from another person by coincidence with the same degree of match is called the match probability. The match probability depends on the reference population and the assumption of independence within and between loci. Because the assumption of independence within loci ignores coancestry effects dependent on the population structure, statistical methods have been developed for interpreting DNA evidence have been developed that account for the presence of coancestry effects, incorporating them into the population structure. Match probability also depends on the genetic relationship between the suspect and the actual criminal (or the alleged father and the biological father). In most cases, however, match probability is calculated on the assumption that the two persons in question are not related to each other, and the calculation of the likelihood ratio tends to overestimate DNA evidence. For this reason, alternative methods have been proposed for assessing genetic relationships. The practice of forensic science has undergone a period of rapid change due to the dramatic evolution of DNA profiling and the related greater sophistication of statistical evaluation of DNA evidence. Forensic inference from DNA evidence is widely used in criminal investigation, parentage lawsuits, and ancestral classification cases as well as in the identification of the remains of deceased people. In this paper, we present relevant statistical concepts and review recently developed statistical methods as well as discussing some practical issues in forensic statistics. We also present statistical methods for ancestral classification based on the analysis of single nucleotide polymorphisms markers that are informative for ancestry, and we describe various statistical methods for estimating postmortem interval), which plays a very important role in screening suspects and solving crime cases that involve the death of an individual, in forensic entomology studies.

커먼레일 연료분사 시스템을 장착한 경량 DME 트럭의 연구 및 개발

정수진,전문수,박정권,Jeong, Soo-Jin,Chon, Mun Soo,Park, Jung-Kwon 한국교통대학교 융복합기술연구소 2012 융ㆍ복합기술연구소 논문집 Vol.2 No.1

In this study, the trucks(2.9-liter) have been developed to use DME as fuel, and performance test of the vehicle's DME engine, power, emissions, fuel economy and vehicle aspects was conducted. For experiments, the fuel system(common-rail injectors and high-pressure pump included) and the engine control logic was developed, and ECU mapping was performed. As a result, the rail pressure from 40MPa to approximately 65% increase compared to the base injector has been confirmed that. Also, the pump discharge flow is 15.5 kg/h when the fuel rail pressure is 400rpm(40 MPa), and the pump discharge flow is 92.1 kg/h when the fuel rail pressure is 2,000rpm(40MPa). The maximum value of full-load torque capability is 25.5kgfm(based on 2,000rpm), and more than 90% compared to the level of the diesel engine were obtained. The DME vehicle was developed in this study, 120 km/h can drive to the stable, and calculated in accordance with the carbon-balance method of fuel consumptions is 5.7 km/L.

의치장착 노인의 주관적 저작수준과 의치만족도의 관련성

정수진,Jung, Su-Jin 중소기업융합학회 2021 융합정보논문지 Vol.11 No.10

본 연구는 의치장착 노인들의 주관적 저작수준과 의치에 대한 만족도의 연관성을 알아보기 위한 연구이다. 자료조사는 2019년 11월 22일부터 2020년 1월 21일까지 대전광역시와 논산시, 공주시, 천안시에 거주하는 65세 이상의 의치장착 노인 212명을 대상으로 분석하였다. 연구결과, 주관적 저작수준이 높을수록 의치 관련하여 정기적으로 치과를 방문할수록 의치만족도가 증가하는 것으로 나타났으며, 의치사용기간이 증가할수록 의치만족도는 감소하는 것으로 나타났다. 이상의 결과를 토대로 의치장착 노인들의 주관적 저작수준과 의치만족도의 향상을 위한 의치사후관리프로그램과 의치수리비용 지원정책 등의 마련이 요구된다. This study is to investigate the relationship between the subjective mastication level of the elderly wearing denture and their satisfaction with dentures. The data was analyzed on 212 denture-wearing elderly people over the age of 65 living in Daejeon, Nonsan, Gongju, and Cheonan from November 22, 2019 to January 21, 2020. As a result of the survey, the higher the subjective mastication level, the more regular dental visits related to dentures showed that the denture satisfaction increases, as the dentures wearing period increases showed that the decrease in denture satisfaction. Based on the above results, it is required to prepare a denture follow-up management program and a denture repair cost support policy to improve the subjective mastication level and denture satisfaction of the elderly with dentures.

B형 간염 바이러스 감염과 연관된 사구체신염의 임상병리학적 특성과 신 조직내에서 HBs Ag 과 HBe Ag의 발현

정수진,김영주,윤혜경,정우영,김영훈,김수영,Jung Soo-Jin,Kim Young-Joo,Yoon Hye-Kyoung,Chung Woo-Yeong,Kim Young-Hoon,Kim Su-Yung 대한소아신장학회 1998 Childhood kidney diseases Vol.2 No.1

목적 : HBV 감염과 연관된 신병증의임상 및 검사소견과 병리학적 소견을 분석하여 그 특징을 규명하고, HBeAg과 HBsAg에 대한 면역조직화학염색을 신생검조직에서 시행하여 이들 항원의 사구체내에서의 면역학적 발현을 관찰하므로써 이 질환의 발생 기전에 대한 이해를 돕고자하였다. 방법 : 1990년 4월부터 1997년 2월까지 사구체신염으로 신조직 생검을 시행하여 부산백병원 해부병리과에 병리조직검사가 의뢰된 증례 중 혈청 HBsAg 양성인 28례를 대상으로 임상 및 검사소견을 조사하였고, 신조직의 광학현미경적, 면역형광학적, 전자현미경적 검사와 HBsAg과 HBeAg 항원에 대한 면역조직화학검사를 시행하였다. 결과 : 1. 연령 분포는 6세에서 73세였으며 소아 환자가 8명이었고 성인 환자는 20명 이었다. 평균 연령은 28세였고, 남녀 비는 3:1 이었다. 내원당시 67.9%에서 혈뇨, 75.0%에서 단백뇨를 보였고 57.2%에서 신증후군을 나타내었다. 전 예에서 혈청 HBsAg이 양성이었고, 혈청 HBeAg은 검사가 시행된 9례 중 6례 (66.6%)에서 양성이었다. 2. 간기능검사가 시행된 11례 중 7례 (63.6%)에서 AST와 ALT치가 증가되어 있었으며, 이중 간생검이 시행된 3례 모두 만성 활동성 간염으로 진단되었다. 3. 28례 중 막성 사구체 신염 (membranous glomerulonephritis: MGN)이 10례 (35.7%)로 가장 많았으며, 메산지움중식성 사구체신염 (mesangioproliferative glomerulonephritis: MesGN)이 8례 (28.6%), 막증식성 사구체 신염 (membranoproliferaive glomerulonephritis : MPGN)은 7례 (25.0%) 그리고 미세변화질환 (minimal change disease : MCD)가 3nl (10.7%)순이었다. 4. HBV와 연관된 MGN에서는 혈관간 세포의 증식 및 혈관간 기질의 확장이 자주 관찰되었으며, 사구체간질 내와 내피하 침윤도 동반되어 MPGN을 시사하는 소견이 함께 관찰되는 예가 많았고, HBV 항원 혈증에 동반된 MPGN에서는 내피하 침윤 뿐 아니라 기저막 내 및 상피세포하 침윤도 종종 관찰되었다. 5. 신조직의 면역조직화학검사상 HBsAg은 모두 음성이었으나 HBeAg은 28례 중 8례 (28.6%)에서 사구체 모세혈관벽을 따라 양성 반응을 나타내었고, 이 중 3례는 혈치 HBeAg 검사를 받았는데 모두 양성이었다. 결론 : HBV와 연관된 사구체신염은 다양한 병리학적 양상을 보여주며, 특히 MGN과 MPGN에서는 전자현미경소견상 두 질환의 특징이 중복되어 나타났고, 사구체내에서 HBeAg이 검출되어 HBV의 활동성 정도와 사구체신염의 발생이 연관성이 있을 것으로 사료되나 더 많은 연구보고가 있어야 하겠다. Purpose : Hepatitis B virus (HBV) infection has been involved in several forms of immune-related glomerulopathy but the pathogenic role of HBV infection is not clear. To evaluate the clinicopathological features of HBV-associated glomerulopathy, a clinicopathological analysis and immunohistochemical stain for HBs Ag and HBe Ag were done. Methods : Clinicopathological features of HBV-associated glomerulopathy were analyzed with renal biopsies in 28 HBsAg seropositive patients from April 1990 to February 1997 at Pusan Paik Hospital, and immunohistochemical evaluation for HBsAg and HBeAg was done in renal tissues. Light microscopic, immunofluorescent and electron microscopic examination and immunohistochemical staining for HBsAg (DAKO) and HBeAg (BIONIKE) of renal tissue were performed. Result ; 1. The age distribution was 6 to 73 years old, and eight were children and 20 were adults. Male : female ratio was 3:1. Nineteen (67.9%) and 21 (75.0%) of 28 cases showed hematuria and proteinuria, respectively at the time of biopsy. Sixteen (57.2%) of them had nephrotic syndrome. 2. Liver function test was performed in 11 patients and seven (63.6%) of them showed increased AST and ALT levels. Liver biopsy was done in three patients and revealed findings of chronic active hepatitis. 3. HBV-associated glomerulopathy was membranous glomerulonephritis (MGN) in 10 (35.7%), mesangiopathy in 8 (28.6%), membranoproliferative glomerulonephritis (MPGN) in 7 (25.0%) and minimal change disease in 3 (10.7%) out of 28 cases. 4. Ultrastructurally HBV-associated MGN showed conspicuous subepithelial deposits with intramembranous, mesangial and subendothelial deposits and proliferation of mesangial cells and matrix, which were suggestive of MPGN. In HBV-associated MPGN, intramembranous and subepithelial deposits were scattered. 5. Immunohistochemical staining revealed no expression for HBsAg, but positive reaction for HBeAg along capillary wall in 8 cases (28.6%), of which 3 cases were checked for serum HBeAg, all showed positivity. Conclusion : HBV-associated glomerulopathy showed a wide morphologic spectrum and overlapping ultrastructural features in MGN and MPGN, and the activity of hepatitis B virus may be related to the development of HBV-associated glomerulopathy but further studies are recommended to confirm this relationship.

A Case of Severe Influenza Infection in a Child with Nephrotic Syndrome on Steroid Therapy

정수진,박성은,이준호,Jung, Su Jin,Park, Sung Eun,Lee, Jun Ho Korean Society of Pediatric Nephrology 2014 Childhood kidney diseases Vol.18 No.1

신증후군 환아에서 감염은 매우 중요한 사망원인이 된다. 독감 바이러스는 매번 겨울철마다 유행하며, 독감 바이러스의 치명률은 건강한 소아에서 호흡기세포융합바이러스의 사망률과 비슷하므로 독감에 의한 감염도 신증후군 환아들에게는 매우 치명적일 수 있다. 독감에 의한 사망률에는 폐렴으로 인한 사망이 많은 부분을 차지한다. 하지만, 독감은 예방접종과 항바이러스 치료제가 존재하므로 치료 및 예방이 가능하다. 그러므로, 적극적인 독감 예방접종과 항바이러스 치료는 신증후군 환자들에게서 치명률을 낮출 수 있을 것으로 생각된다. 저자들은 신증후군 치료중에 A형 독감(H1N1)에 의한 폐렴에 걸린 7세 남아를 경험하였기에 보고하는 바이다. Infection is the most important cause of death in children with nephrotic syndrome. Influenza viral infections can be fatal for these children, given the annual outbreak of this virus, with the mortality rate being similar to that of respiratory syncytial virus in healthy children. Pneumonia is recognized as the most important complication of influenza infections, as it is associated with high death rates. However, the influenza vaccine, as well as antiviral agents, can be used for prevention and treatment. Therefore, aggressive management with influenza vaccination and antiviral agents will lower the overall mortality rate in children with nephrotic syndrome. Here we report the case of a 7-year-old boy with nephrotic syndrome and influenza A virus (H1N1) pneumonia.

An 8-month-old Male Infant with High Grade Vesicoureteral Reflux who Developed Incomplete Kawasaki disease after Recurrent Pyelonephritis

정수진,박성은,이준호,Jung, Su Jin,Park, Sung Eun,Lee, Jun Ho Korean Society of Pediatric Nephrology 2014 Childhood kidney diseases Vol.18 No.1

가와사끼병은 전신성 혈관염을 일으키는 질환중의 하나로 여러 장기들을 침범할 수 있다. 신장증세로는 농뇨, 혈뇨, 단백뇨, 간질성 신염, 급성 신부전증, 용혈성 요독 증후군, 신반흔 등이 있다. 가와사끼병의 신장침범에 대한 병리기전은 아직 알려져 있지 않지만, 자가면역질환으로 인한 것으로 사려된다. 가와사끼병이 요로감염 이 후에 발병한다는 몇몇 보고들이 있었다. 하지만, 이미 보고된 논문들에 포함된 많은 요로감염 환자들은 신장방광 초음파, DMSA 스캔이나 배뇨중 요도방광조영술 등을 모두 받은 경우는 없었다. 이에 저자들은 급성 신우신염이 재발한 후 불완전 가와사끼병이 발생한 고도의 방광요관역류가 있는 8개월 남아를 보고하는 바이다. 급성 신우신염은 가와사끼병의 초기 증세일 수 있다. 그런 경우, 환아가 가와사끼병으로 확진되더라도 요로감염 진료지침에 따라 요로기형에 대한 이미지 검사를 시행할 필요가 있다고 생각한다. Kawasaki disease (KD) is a systemic vasculitis that can affect many organ systems. Renal manifestations include pyuria, hematuria, proteinuria, tubulointerstitial nephritis, acute renal failure, hemolytic uremic syndrome, or renal scarring. Although its precise pathogenesis remains unknown, it is considered an autoimmune disease. In the literature, it has been reported that KD may develop in conjunction with urinary tract infections. However, many of these previous studies did not use imaging methods such as renal sonograms, dimercaptosuccinic acid renal scans, and voiding urethrocystograms. We report a case of an 8-month old male infant with high grade vesicoureteral reflux, who developed incomplete KD after recurrent pyelonephritis. Acute pyelonephritis can be an early manifestation of KD. Such cases require the evaluation of urinary tract anomalies according to the guidelines for the management of urinary tract infections.

디자인의 방법론적 서술 - Architecture : SIE - Simple / Identity / Emotion

정수진,Jung, Su-Jin 대한건축사협회 2009 建築士 Vol.2009 No.9