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전희진,최장규,최수정,윤신희,김진웅,윤기동,이창욱 한국생약학회 2015 Natural Product Sciences Vol.21 No.1
Anthocyanins are water soluble plant pigments which are responsible for the blue, red, pink, violet colors in several plant organs such as flowers, fruits, leaves and roots. In recent years, anthocyanin-rich foods have been favored as dietary supplements and health care products due to diverse biological activities of anthocyanins including antioxidant, anti-allergic, anti-diabetic, anti-microbial, anti-cancer and preventing cardiovascular disease. High-performance countercurrent chromatography (HPCCC) coupled with reversed-phase medium pressure liquid chromatography (RP MPLC) method was applied for the rapid and efficient isolation of cyanidin 3-glucoside (C3G) and peonidin 3-glucoside (P3G) from black rice (Oryza sativa L., Poaceae). The crude black rice extract (500 mg) was subjected to HPCCC using two-phase solvent system composed of tert-butyl methyl ether/n-butanol/acetonitrile/0.01% trifluoroacetic acid (TBME/B/A/0.01% TFA, 1 : 3 : 1 : 5, v/v, flow rate - 4.5 mL/min, reversed phase mode) to give enriched anthocyanin extract (37.4 mg), and enriched anthocyanin extract was sequentially chromatographed on RP-MPLC to yield C3G (16.5 mg) and P3G (8.7 mg). The recovery rate and purity of isolated C3G were 76.0% and 98.2%, respectively, and those of P3G were 58.3% and 96.3%, respectively. The present study indicates that HPCCC coupled with RP-MPLC method is more rapid and efficient than multi-step conventional column chromatography for the separation of anthocyanins.
한·일 그림책 무생물 캐릭터 비교 연구 : 이불 캐릭터를 중심으로
전희진,김경희 글로벌문화콘텐츠학회 2019 글로벌문화콘텐츠학회 학술대회 Vol.2019 No.2
그림책은 글과 그림을 통해 메시지를 전하는 예술성과 텍스트성을 갖춘 복합 출판물이다. 이야기 속에 등장하는 다양한 캐릭터들은 크게 인간, 생물, 무생물 등으로 나뉜다. 무생물 중 ‘이불’은 국적, 지역, 연령, 성별 등에 상관없이 누구나 쉽게 이해하고 친근함을 느끼는 소재로 자주 등장하는 캐릭터이다. 또한 잠과 휴식이라는 필수적인 일상생활의 한 부분을 상징한다는 점에서 이불은 누구나가 큰 거부감 없이 받아들일 수 있는 문화할인율이 낮은 캐릭터라고 할 수 있다. 그림책을 보는 독자들은 어른의 경우에도 자신의 어린 시절을 떠올리거나 이불과 관련된 비슷한 경험이나 감정을 공감하기도 한다. 일본은 오래된 그림책의 역사와 함께 그에 따른 다양한 캐릭터와 파생상품 제작이 발달된 나라이다. 인접해 있는 한국에도 일본 그림책들의 유입과 더불어 최근 많은 그림책들이 제작되고 있는 상황이다. 본 연구에서는 2000년대 이후 한국과 일본의 그림책에 등장하는 이불 캐릭터의 비교 분석을 통하여 무생물인 이불 캐릭터의 발전 가능성에 대해 살펴보고자 한다.
전희진,정미자,Kevin Dawson,Raymond L. Rodriguez,Soung-Jin Houng,Sung-Yun Cho,Jungae Jeun,Jin-Young Kim,Kyung Heon Kim,Kuen Woo Park,Cheong-Tae Kim,이성준 한국식품과학회 2010 Food Science and Biotechnology Vol.19 No.1
Hypolipidemic effects of Agastache rugosa essential oil (AREO) were investigated. Gas chromatographymass spectrometry (GC-MS) analysis showed that the major compound in AREO is limonene (47%, w/w). AREO (1 mg/mL) markedly reduced low density lipoprotein (LDL) oxidation (−93%). After 3-week feeding of AREO,plasma cholesterol (−28%) and triglyceride levels (−26%)were significantly decreased in C57BL/6J mice. Mouse hepatic transcriptome profiling with oligonucleotide microarray revealed that AREO altered the expression of 2,524 genes. Notably, significant reductions in sterol regulatory element binding factor (SREBF)-1 and SREBF-2 mRNA levels were detected. Protein expression of HMG-CoA reductase, a major target for SREBP-2, was reduced in HepG2 cells (−36%) and in mouse liver (−35%). AREO also significantly increased mRNA (+40%) and protein (+83%) expression of the LDL receptor in HepG2cells and mouse liver, respectively. Our findings suggest that AREO may prevent atherosclerosis via the inhibition of LDL oxidation, down-regulation of SREBF-2 and HMG-CoA reductase expression, and up-regulation of LDL receptor expression.
Red Yeast Barley Reduces Plasma Glucose Levels and Activates AMPK Phosphorylation in db/db Mice
전희진,Young-Mi Choi,Minh Hien Hoang,Yoayao Jia,이지혜,이성준 한국식품과학회 2011 Food Science and Biotechnology Vol.20 No.5
Red yeast (Monascus purpureus) fermented over rice has a limited hypoglycemic activity. To enhance its glucose-lowering effect, we fermented red yeast over waxy barley, a hypoglycemic grain with high levels of fibers and β-glucans, and investigated the metabolic effects of red yeast barley (RYB) in high-fat-fed hyperglycemic db/db mice for 6 weeks. The fasting glucose levels were significantly reduced in the RYB group at 6 weeks by 25%(p<0.05), as was the glucose tolerance (−27% of area under the curve in RYB vs. controls, p<0.05). Plasma insulin levels and the expression of PPAR-γ were unaltered, however, the phosphorylation activation of hepatic AMP-activated protein kinase (AMPK) was increased significantly in RYB group compared with controls suggesting that hypoglycemic effect of RYB may be achieved by AMPK-dependent mechanism. RYB may be used as a hypoglycemic functional food modulating cellular AMPK activity.
한·일 그림책의 무생물 캐릭터 비교연구- 이불 캐릭터의 의인화를 중심으로 -
전희진,김경희 한국일어일문학회 2020 日語日文學硏究 Vol.112 No.-
This study compares the inner and outer images of the anthropomorphic blanket characters focusing on the blanket characters of the picture books published in Korea and Japan after the 2000s in order to create the inanimate characters of the Korean picture books. The analysis identifies the similarities and differences of the anthropomorphic blanket characters used in Korean and Japanese picture books. The similarities between the Korean and Japanese blanket characters are that the gender and age of the blanket characters are not clearly shown, that they are able to speak and act, and that they show warm-hearted and cozy images by conveying the emotions with their facial expressions. The differences of these two blanket characters have been detected as well. First, the Korean blanket characters are similarly drawn to the actual blankets so that their arms and legs are ambiguously separated. In addition, home is the background of the story in most cases and humans are around them as the side characters. Furthermore, the blanket characters do not show their willingness. On the other hand, the arms and legs of the Japanese blanket characters are clearly described. Also, the Japanese picture books feature the varied backgrounds of the story and the various side characters, and the Japanese blanket characters are described as goal-oriented. This study has implications for the creation of the blanket characters: this study explores the characters whose cultural discount rate is low. In addition, this study emphasizes the use of differentiated appearances, the diversification of the background of the story and side characters, the consideration of gender roles and values, and the commercialization of the blanket characters. I hope that awareness of the characters in the picture books will be raised and various studies on the inanimate characters of the picture books will be conducted through this study.
아름다운 노후 건강한 노년 - 노후에는 어디서 살면 좋을까?
전희진,Jeon, Hui-Jin 한국건강관리협회 2013 건강소식 Vol.37 No.2
'지금 살고 있는 내 집에서 그냥 노후를 보낼까? 아니면 한적한 전원주택으로 옮겨 볼까? 편리한 시설을 갖춘 시니어타운에 들어가는 것도 좋을 것 같은데${\cdots}$'. 은퇴하면 어디서 살지 고민하는 중장년층이 많다. 특히 활동 반경이 축소되고 환경에 대한 적응능력이 떨어지는 노년기엔 사는 곳에 따라 삶의 질이 매우 달라질 수 있다. 건강하고 행복한 노후를 보내기 위해서는 주거 계획을 잘 세우고 주변 환경을 잘 활용하는 것이 필요하다.