원료별 식이섬유의 밀가루 대체 시 가공적성 및 전분소화지연효과

이홍임 ( Hong Im Lee ),이현규 ( Hyeon Gyu Lee ),배인영 ( In Young Bae ) 한국산업식품공학회 2013 산업 식품공학 Vol.17 No.4

귀리, 콩, 감자, 밀에서 유래한 다양한 식이섬유를 밀가루 대신 10-40%까지 대체함에 따른 수화능, 동적점탄성, 용매흡착능 및 in vitro starch digestion을 비교하였다. 귀리, 콩, 감자, 밀에서 유래한 다양한 식이섬유를 식이섬유의 대체비율이 증가할수록 수분흡착능과 팽윤력은 증가한 반면, 수분용해도는 감소하였다. 밀가루 대신 콩과 감자 식이섬유를 대체함에 따라 동적점탄성은 증가하였으나, 귀리와 밀 식이섬유 대체에서는 오히려 감소하는 경향을 보였다. 식이섬유 대체에 따른 밀가루의 용매흡착능 변화를 분석한 결과, 낮은 대체량의 귀리 식이섬유와 높은 대체량의 콩과 감자 식이섬유가 활용 가능성을 보였다. 원료별 식이섬유 대체 시 밀가루 겔의 전분소화 패턴은 식이섬유 대체 비율이 증가함에 따라 glucose 방출은 감소하였으나, 원료별 특성에 따른 유의적인 차이는 없었다. 특히, 밀식이섬유를 제외한 귀리, 콩, 감자 식이섬유는 모두 RDS감소와 RS 증가에 따른 pGI 저하를 보여 실제 식품소재로 활용 시가공적성을 유지할 수 있다면 전분소화지연효과를 기대할 수 있음을 확인할 수 있었다. 한편, 식이섬유의 원료에 따른 식이섬유 조성과 전분소화 관련 특성 간 상관관계를 분석한 결과, 전분소화를 지연시키는 효과는 수용성 식이섬유보다는 불용성과 총식이섬유 함량이 중요한 인자임을 알 수 있었다. Wheat flour in a gel model was replaced with dietary fibers from various sources (oat, pea, potato, and wheat) in order to investigate their baking quality and in vitro starch digestibility. Then their hydration properties and solvent retention capacities (SRC) were measured. Over all, the gels with dietary fibers experienced increased water absorption index, swelling power, and SRC values, while water solubility decreased dose-dependently. The storage modulus (G`) and loss modulus (G") of the wheat flour gel increased by the addition of pea and potato fibers but decreased by oat and wheat fibers. The wheat flour gels with dietary fibers showed considerable decreases in the amount of released glucose. Also wheat flour replacement with dietary fibers lowered RDS and increased RS. Among SRC values, water and sucrose showed significant positive correlations with TDF and IDF. The contents of TDF, IDF, and SDF were highly correlated with RS (positive) and pGI (negative). Specially, for lowering starch digestibility, TDF and IDF were more important factors than SDF.

A Raman Spectroscopic Study on Subtilisin Family

이홍인,김명수,서세원,Lee, Hong-In,Kim, Myung-Soo,Suh, Se-Won 생화학분자생물학회 1989 한국생화학회지 Vol.22 No.3

결정 상태의 proteinase K로부터 라만스펙트럼을 얻었고, 이의 잠정적 해석을 시도하였고, 몇 가지 라만띠를 사용하여 정량적 분석이 가능한지를 살펴보았다. 스펙트럼의 amide I 띠의 Fourier deconvolution 결과로부터 라만분광법에 의한 단백질 이차구조 측정의 한 방법으로 Fourier deconvolution이 쓰일 수 있다는 종전의 제안을 확인하였다. Silver sol을 써서 subtilisin Carlsberg의 표면중강 라만스펙트럼을 얻었고, 이의 해석을 시도하였다. Raman spectrum of proteinase K in the crystalline state was obtained, its tentative assignment has been attempted, and the possibility of using several Raman bands for quantitative analyses has been explored. The result of Fourier deconvolution of amide I band region in the spectrum provides further support to our previous suggestion that the Fourier deconvolution can be a viable approach to the estimation of protein secondary structures by Raman spectroscopy. The surface-enhanced Raman spectrum (SERS) of subtilisin Carlsberg in the silver sol was obtained and its preliminary interpretation is given.

다른 연료를 이용한 이중 풀 화염의 상호작용이 CO 및 Soot yield에 미치는 영향

이홍인(Hong-In Lee),장효연(Hyo-Yeon Jang),문선여(Sun-Yeo Mun),황철홍(Cheol-Hong Hwang) 한국화재소방학회 2022 한국화재소방학회 학술대회 논문집 Vol.2022 No.추계

최근 국내 건축물의 고층화, 복합화 및 대형화에 따라서 화재 위험성 극복을 위해 성능위주설계(performance based design, PBD)가 시행되고 있다. 일반적으로 화재위험성은 PBD를 통해 단순한 Timeline 분석에 근거하여 평가되며, 국내는 PBD의 신뢰성 향상을 위하여 지속적으로 다양한 연구가 수행되고 있다. 구체적으로 PBD 수행 시 화재시뮬레이션(Fire Dynamics Simulator, FDS)의 입력인자 중 연기농도 및 가시도의 예측결과에 큰 영향을 미칠 수 있는 CO 및 Soot yield에 대한 정확도의 중요성이 보고된 바 있다. 이때 FDS에 입력되는 화원의 정보는 일반적으로 단일 또는 복합 소재의 가연물에서 측정된 값이 적용되며, 복합 소재는 동일한 용도라도 복잡한 구성 성분의 차이로 인하여 입력 값을 특정 짓기 어렵다. 이에 본 연구진은 예비 연구로서, 복합 소재를 상대적으로 용이하게 접근하고자 액체 연료가 적용되었으며, 서로 다른 연료의 풀 화염이 상호작용을 통해 CO 및 Soot yield에 미치는 영향에 대한 연구를 수행하고자 한다. 액체 풀 화염의 특성 상 지속적인 열이 가해질 때 발생되는 비등을 방지하여 측정값의 정확성 확보를 위해 외부 버너에 물을 통해 냉각되었다. 이때 연료로는 에탄올(Ethanol), 헵탄(Heptane), 등유(Kerosene), 톨루엔(Toluene)이 적용되었으며, 다양한 조합을 통해 이중 풀 화염이 형성되었다. 이중 풀 화염을 이용하여 충분한 거리를 확보함에 따라 두 개의 화염이 독립적으로 존재하거나, 근접한 거리에 의해 화염이 융합(merging)되어 서로의 화염에 상호작용으로 인한 측정값이 비교되었다. 결론적으로 이중 풀 화염에 적용된 서로 다른 연료는 거리가 변화됨에 따라 미치는 상호작용에 의한 CO 및 Soot yield가 검토되었다. 이는 복합 소재 가연물에서 발생되는 복잡한 현상의 규명을 위한 초기 연구로써, 추후 다양한 Polymer 계열의 시편을 통해 단계적으로 접근하여 CO 및 Soot yield의 신뢰성 향상에 기여할 수 있을 것으로 기대된다.

Subtilisin 계에 대한 라만 분광학적 연구

이홍인,김명수,서세원 ( Hong In Lee,Myung Soo Kim,Se Won Suh ) 생화학분자생물학회 1989 BMB Reports Vol.22 No.3

Raman spectrum of proteinase K in the crystalline state was obtained, its tentative assignment has been attempted, and the possibility of using several Raman bands for quantitative analyses has been explored. The result of Fourier deconvolution of amide I band region in the spectrum provides further support to our previous suggestion that the Fourier deconvolution can be a viable approach to the estimation of protein secondary structures by Raman spectroscopy. The surface-enhanced Raman spectrum (SERS) of subtilisin Carlsberg in the silver sol was obtained and its preliminary interpretation is given.

케이블의 화재확산 시뮬레이션을 위한 열분해 물성 측정

문선여(Sun-Yeo Mun),조재호(Jae-Ho Cho),이홍인(Hong-In Lee),황철홍(Cheol-Hong Hwang) 한국화재소방학회 2022 한국화재소방학회논문지 Vol.36 No.6

본 연구에서는 다중 재료로 구성된 케이블의 화재확산 시뮬레이션을 위해 요구되는 열분해 물성 측정 및 검토가 수행되었다. 주요 결과로써, 케이블은 유형에 관계없이 전형적으로 2단계 열분해 반응이 확인되었다. 단일 승온 속도에 의해 산출되는 {Tₚ}와 {rₚ}를 적용하는 입력 방법 보다는 다양한 승온속도에 의해 산출되는 Kissinger 방법 및 flynn-wall-ozawa (FWO) 방법이 보다 정확한 화재확산 예측이 가능 할 것으로 예상된다. 그 결과 난연성 케이블(CLASS 1E 및 TFR-8)의 경우 Kissinger 방법의 적용은 FWO 방법의 적용보다 화재확산 속도를 과다 예측할 가능성이 있으며, PVC 케이블(VCTF)의 경우 화재확산 속도를 과소 예측할 가능성이 있다. The analysis and review of the thermal decomposition properties required for the fire spread simulation of cables composed of multiple materials were performed. Thus, a typical two-step pyrolysis reaction was identified independent of cable type. It is expected that the Kissinger and flynn wall ozawa (FWO) methods, which are calculated using various – – heating rates, more accurately predict fire spread than the input method that uses the and values calculated using a single heating rate. Consequently, in the case of flame-retardant cables (CLASS 1E and TFR-8), the Kissinger method is more likely to overestimate the fire spread rate than the FWO method. In the case of polyvinyl chloride (PVC) cables (vinyl cabtire power cable, VCTF), the fire spread rate may be underestimated.

두개부와 흉부 CT 검사시 Bismuth 차폐재를 이용한 안구의 렌즈와 유방의 선량감소에 대한 평가

변정인(Jung in Byun),남윤철(Yoon chul Nam),이홍(Hong Lee),신상보(Sang bo Shin),한동균(Dong kyoon Han) 대한CT영상기술학회 2008 대한CT영상기술학회지 Vol.10 No.1

Purpose Bismuth shield can filter twice in that penetrates X-ray, which is essential in diagnosis, and it also partially decreases skin dose. Hence, it is necessary to study the effects in reduction of absorbed dose on highly sensitive organs, which are included in the regions of cranial and chest CT exams. Materials and methods All exams were proceeded on LlghtSpeed 16MDCT (GE Medical System, Milwaukee, U.S.A.), Rando phantom (Model RAN-110, Churchin associate LID., USA) and Glass dosimetry system(GD-351,8.5mm, FGD-1000) for the measurement of radiation dose. In addition, AttenuRad radiation protection devices of eyeballs & breast (F&L Medical Products Co.) are used for protection of sensitive organs. In cranial examination, the brain CT protocols was used for the examinations, and the summary of it is as followed: The glass radiation elements were put on left and right lens of phantom eyeballs, and the radiation before and after the use of Bismuth shield were measured twice when 120kVp of current were changed into 150mAs, 200mAs, and 200mAs, and when 250mAs were changed into 100kVp, 120kVp, and 140kVp. In chest examination, low-dose protocol and chest routine protocol are used for the examination. The conditions of low-dose protocol are as followed:120kVp, noise index 11.57(10~50mA), tube rotation time 0.8sec, pitch 1.375, and table speed 13.75mm/sec. Also, the conditions of chest routine CT protocol are 120kVp, noise index 15.86(160~250mA), tube rotation time 0.8sec, pitch 1.35, and table speed 13.5mm/sec. The glass elements were put on the both nipples of phantom and the radiation before and after the use of bismuth shield were measured twice. When the shield is used, rubber-made spacer(1cm) should be on the breasts, followed by bismuth shield, because it decreases not only the scattering ray absorption into breast wall caused by bismuth shield but image artifact potentially. Results The result of the measurement of orbit shielding during cranial examination. The results of measurements of the radiation(from 120kVp to 150, 200, 250 and 300mAs) before and after the use of bismuth shield are as followed: from 18.4±0.3mGy to 10.25±0.5rnGy(44.3% decrease) at 150mAs; from 23.9±0.9mGy to 13.9±0.1mGy(41.5% decrease) at 200mAs; from 37.3±0.3mGy to 19.8±0.9mGy(47.1% decrease) at 250mAs; and from 47.8±3.4mGy to 24.4±1.4mGy(46.8% decrease) at 300mAs. On the other hand, the measurements of radiation(from 250mAs to 100, 120, and 140 kVp) before and after the use of bismuth shield are as followed: from 22.9±0.2mGy to 22.9±0.2mGy(51.2% decrease) at 100kVp; from 34.4±0.9mGy to 19.5±0.2mGy(43.3% decrease) at 120kVp; and from 49.5 ±4.4mGy to 29±1.2mGy(41.4% decrease) at 140kVp. The result of the measurement of orbit shielding during breast examination. In low-dose protocol, the results of measurements of the radiation before and after the use of bismuth shield are 3.16±0.02mGy and 2.44±0.03mGy(22.78% decrease), respectively, and in chest routine protocol, the results were 14.45±1.08mGy and 11.93±0.21mGy(17.43% decrease), respectively. Conclusion In cranial examination, there was not much change in the radiation dose of eye lens with an application of bismuth shield, even increases of mAs with constant kVp. On the other hand, the rate of reduction of radiation dose by bismuth shield is seen with constant mAs and increase of kVp. Due to the use of bismuth shield, radiation dose has been decreased about 22.8%in low-dose study, and 17.4% in chest routine study. In our hospital, the use of bismuth shield of orbit is not applied to adults, but applied to some infants only when brain CT exam was operated to them. The breast shield is applied, as a test, to women under 50 years old. According to this study, the results show obviously that the use of the bismuth shield can reduce radiation dose of highly radiation-sensitive organs. As mentioned before, the amount of radiation that eye balls received at 250mAs(at

폐암에 의한 폐절제 후 운동부하 폐기능 검사 - 4 주 및 6 개월 추적검사 -

인병현(Byeong Hyun In),문성기(Sung Gi Moon),김현중(Hyun Jung Kim),김형식(Hyeong Sik Kim),이홍(Hong Lee),이길홍(Kil Hong Rhee),이흥범(Heung Bum Lee),이용철(Yong Chul Lee),이양근(Yang Keun Rhee) 대한내과학회 1998 대한내과학회지 Vol.54 No.3

N/A Objectives: At present, the overall incidence of lung cancer is increasing, causing the age-adjusted lung cancer death rate to double every 15 years. Surgical resection of the tumor offers the best prospect of long-term survival in patients with lung cancer. Accurate prediction of postoperative ventilatory function should be helpful in determining in which patients the risk of surgery are acceptable. Exercise pulmonary function test has been widely applied to objective measure of work capacity, and can be extremely helpful for investigating exertional dyspnea. But no attempt is made to assess the contribution of the lung to be resected to performance, and it has been advocated as an additional predictor of postoperative complications. The present investigation was designed to evaluate the factors such as FEV1, FVC, VEmax, Vo2max, anaerobic threshold, heart rate reserve, breathing reserve and the corelation between FEV1 and VO2max at 4 weeks and 6months after resection in patients with lung cancer. Methods : The eighteen of patients with lung cancer who considered surgically resectable underwent progressively incremental exercise test to symptom-limited stage before opera-tion, and also have done at surgical resection after 4 weeks, and 6 momths. Measurements were made of metabolic, cardiorespiratory, blood gases and symptoms during exercise test. Results: 1) There were significant decreases in FEV1, FVC, VC2max, VE max in 4 weeks operation and were more decreased in FEV1, FVC, VE max with significance, but fall in VO2max without significance in 6 month after operation. 2) There was a significant correlation between the decrease of FEV1 and that of VO2max in 6 month after operation. Conclusions This result suggests that change of FEV1 is a relatively useful predictor of change in exercise performance after lung resection in 6 month after operation.

리더-하위자 관계 발전 단계와 관계행동의 및 태도에 관한 연구

나인표(In Pyo Na),이홍(Hong Lee),전상길(Sang Gil Jeon) 대한리더십학회 2004 리더십연구 Vol.1 No.1

본 연구는 리더-하위자간의 관계발전이 리더-하위자 간의 관계행위(협상허용범위, 조직시민행동) 및 관계태도(하위자의 직무태도)에 어떤 영향을 미치는 가를 실증적으로 분석하고자 하였다. 리더-하위자 간의 간계발전은 성숙-미성숙단계로 구분되었다. 이들 관계특성을 측정하는 변수로는 존경, 신뢰, 의무 매력이 사용되었다. 인구의 수행을 위한 표본은 서울, 경기지역에 소재한 15개 회사의 59개부서의 하위직원들을 대상으로 수집되었다. 가설검증에 앞서 관계 특성변수에 의한 관계단계를 확인은 미성숙 단계가 가지는 특성을 가지고 있었으며, 군집II는 성숙 단계가 가지는 특성을 보였다. 이를 기반으로 가설검증을 하였다. 분석겨롸 성숙될수록 협상허용범위와 조직시민행동이 값이 유의적으로 높아짐을 확인하였으며 하위자의 직무만족 역시 높아짐을 확인할 수 있었다. 끝으로 연구의 의의와 한계를 제시하였다. The aim of the current study is to address a research question that how the relationship development between leader and follower impacts relationship behaviors (negotiationg latitude and organizational citizenship behavior) and attitude (job satisfaction). The relationship development was categorized into mature and immature stages. For the variables to define relationship development stage, respect, trust, obligation, and liking were chosen. The sample for the study was collected from followers working for 15 companies in Kyung-gi area. Before the hypothesis testing, cluster analysis was performed. Two groups were identified. First group represented a group belonging to immature stage, and second one was identified as a group belonging to mature stage. On the two clusters, hypothesis testing was performed. Analysis revealed that negotiating latitude, organizational citizenship behavior and job satisfaction were significantly different between groups in immature and mature stages. Various implications and some limitations were also discussed at the end of the study.

외래환자 진료 프로세스를 위한 인터넷 기반 Generic 시뮬레이션 모델

구정인(Jeongin Koo),이기호(Giho Lee),이종성(Jongsung Lee),이홍(Hong Li),김병인(Byung-In Kim) 한국경영과학회 2012 韓國經營科學會誌 Vol.37 No.4

This paper introduces an Internet based generic simulator for outpatient clinics, named PIOS (Postech Internetbased Outpatient Simulator). Unlike other simulation tools, PIOS is operated on the Internet, is straightforward to use for outpatient process analysis, and is open to public via http://logistics.postech.ac.kr/pios with free of charge. Therefore, non simulation expert users such as hospital administrators and managers can easily access to PIOS and conduct simulation study by themselves. In this paper, we describe the main components and programming logic of PIOS, and demonstrate its validity by comparing the output results of PIOS and a commercial software package.

결핵성 기관지 협착 환자에서 팽창성 금속 스텐트 시술후 발생한 기관지 폐색 2례

이홍,김현철,문치영,김인희,이흥범,이용철,이양근 의과학연구소 1997 全北醫大論文集 Vol.21 No.2

Expandible metallic stents(Gianturco type) were used in airway narrowing due to tumoral compression, post-surgical stenosis, posttransplantation lesion, posttraumatic lesion, and tracheobronchial malacia. Some papers reported that the complication of self-extending metalic stents were granuloma formation, stent migration, localized inflammation, fatal massive hemoptysis, wall perforation, obstruction, and respiratory distress etc. Expandible metallic stents were used successfully in tuberculous bronchial stenosis that do not respond to medical therapy. But there was little long-term follow-up report after stent insertion. We report two cases of bronchial obstruction after successful Gianturco metallic stent insertion due to tuberculous bronchial stenosis.