내시경적 유두 괄약근 절개술 후 지연성 출혈을 보인 총담관 결석 치험 1례

이창희,이윤경,채현석,김동언,김영훈,한승훈,이익준,Lee, Chang-Hee,Lee, Yoon-Kyung,Chae, Hyun-Seok,Kim, Dong-Un,Kim, Young-Hoon,Han, Seung-Hoon,Lee, Ik-Jun 대한소아소화기영양학회 2000 Pediatric gastroenterology, hepatology & nutrition Vol.3 No.2

Common bile duct stones are an unusual occurrence in children. Endoscopic retrograde cholangiopancreaticography and endoscopic papillary sphincterotomy are excellent tool for diagnosis and therapy. Bleeding after endoscopic papillary sphincterotomy occurs in approximately 0.5~12% of procedures. We experienced a case of common bile duct stone in 5-year-old boy. After endoscopic papillary sphincterotomy, the stone was passed. 5 days after the procedure bleeding occurred, but it was controlled spontaneously.

Mie 산란 방법과 엔트로피 해석 방법을 이용한 혼합연료비에 따른 분무 균질도 특성에 관한 연구

이창희,이기형,이창식,배재일,Lee, Chang-Hee,Lee, Ki-Hyung,Lee, Chang-Sik,Bae, Jae-Il 대한기계학회 2003 大韓機械學會論文集B Vol.27 No.1

In this study, his technique was applied to a GDI spray in order to investigate the mixture distribution. In addition, the homogeneity degree and diffusion effect according to ambient temperature in the high pressure chamber were analyzed by using an entropy analysis method. From this experiment, we could find that entropy analysis is very effective method for the analysis of mixture formation, and the entropy values increase with the progress of uniformity in diffusion Process. we tried to provide the fundamental data for parameter which effects on the spray macroscopic characteristics with mixture ratio of diesel and gasoline. In addition, the mixture formation was analyzed by using entropy analysis. The entropy analysis is based on the concept of statistical entropy, and it identifies the degree of homogeneity in the fuel concentration. From the entropy analysis results we could find that the direct diffusion phenomena is a dominant factor in the formation of a homogeneous mixture at downstream of GDI spray especially in vaporizing conditions. As to increasing ambient temperature and increasing gasoline rate, the entropy intensity using the statistic thermodynamics method is increased because evaporation rate is higher gasoline than diesel.

양자펌프 억제제에 반응을 보이지 않은 인후두 역류질환 환자에서 고해상도 식도 내압검사의 분석

이창희,이현섭,진성민,이상혁,Lee, Chang-Hee,Lee, Hyun-Sub,Jin, Sung-Min,Lee, Sang-Hyuk 대한후두음성언어의학회 2011 대한후두음성언어의학회지 Vol.22 No.2

Background and Objectives : Laryngopharyngeal reflux disease (LPRD) originates from regurgitation of gastric contents to the laryngopharynx, and it is relatively common disease in otolaryngology. Proton-pump inhibitor (PPI) medication is frequently using treatment method in present time, but controversies exist regarding treatment for it. High-resolution manometry (HRM) system is a newly developed device that using 36 channels and pressure topography plotting program, checking the function and status of esophagus. The aim of this study was to evaluate clinical usefulness of HRM in LPRD patients who do not response to PPI medication. Subjects and Method : From July 2009 to July 2010, a total of 99 patients who were suspected LPRD according to symptoms (Reflux Symptom Index >13) and laryngoscopic findings (Reflux Finding Score >7) were retrospectively enrolled in this study. Patients were consisted of 31 men and 68 women, the mean age was 51.8 years, the mean BMI was 22.46. Patients have taken PPI medication for 2 months, after medication, they performed HRM. Comparative analysis was performed with results of the difference in symptoms. Results : In 99 patients, 37 patients (37.4%) show not improvement of LPRD symptoms after PPI medication. Among them, 18 patients (48.6%) showed abnormal findings that were classified as Peristaltic dysfunction (38.9%), Diffuse esophageal spasm (11.1%), Relaxation impairment of LES (11.1%), Achalasia (5.6%), Hypotensive LES (11.1%), Relaxation impairment of UES (11.1%), Nutcracker esophagus (5.6%), Decreased resting pressure (5.6%). Other 62 patients (62.6%) show improvement of LPRD symptoms, 23 patients (37.1%) showed abnormal findings. Most common finding was Peristaltic dysfunction (43.4%) More prevalent abnormal findings of HRM were found in patients who revealed no response to PPI medication (48.6% vs. 37.1%), but it does not reach the statistical significance. Conclusion : Although statistical significances is not showed, the difference observed in the frequency of HRM abnormal finding between response and no response for PPI medication. It has been estimated that HRM may be used to determine differential diagnosis in patients with LPRD. Further studies in lager population containing normal controls will be needed to prove clinical usefulness.

연습용 10-20 Electrode System을 이용한 뇌파검사 실습의 효율성과 만족도 평가

이창희,김대진,최정수,이종우,이민우,조재욱,김성욱,Lee, Chang Hee,Kim, Dae Jin,Choi, Jeong Su,Lee, Jong-Woo,Lee, Min Woo,Cho, Jae Wook,Kim, Suhng Wook 대한임상검사과학회 2017 대한임상검사과학회지(KJCLS) Vol.49 No.3

Electroencephalography (EEG) is distinct from other medical imaging tests in that it is a functional test that helps to diagnosis disorders related to the brain, such as epilepsy. The most important abilities for a medical technologist when performing an EEG are knowing the exact location of the electrode and recording the EEG wave clearly, except for artifacts. Although theoretical education and practical training are both included in the curriculum for improving these abilities, sufficient practical training has been lacking due to problems like expensive equipment and insufficient practical training time. We try to solve these issues by manufacturing the training 10-20 electrode system and by estimating the efficiency and satisfaction of the training 10-20 electrode system through a questionnaire. The time required for practical training using this system was $43.58{\pm}9.647min$, which proved to be efficient. The satisfaction score of participants who experienced curriculum practical training was improved from $7.21{\pm}2.285$ to $9.46{\pm}1.166$. Based on these findings, it is considered that practical training via the use of the training 10-20 electrode system will solve the problems, such as lack of equipment and insufficient practical training time. Nonetheless, to further improve the training 10-20 electrode system, it must overcome the limitations of developing a device capable of checking the actual brain waves and validating the exact location of electrode attachment.

양자펌프 억제제에 반응을 보이지 않은 인후두 역류질환 환자에서 고해상도 식도 내압검사의 분석

이창희,이현섭,진성민,이상혁,Lee, Chang-Hee,Lee, Hyun-Sub,Jin, Sung-Min,Lee, Sang-Hyuk 대한후두음성언어의학회 2012 대한후두음성언어의학회지 Vol.23 No.1

Background and Objectives : Laryngopharyngeal reflux disease (LPRD) originates from regurgitation of gastric contents to the laryngopharynx, and it is relatively common disease in otolaryngology. Proton-pump inhibitor (PPI) medication is frequently using treatment method in present time, but controversies exist regarding treatment for it. High-resolution manometry (HRM) system is a newly developed device that using 36 channels and pressure topography plotting program, checking the function and status of esophagus. The aim of this study was to evaluate clinical usefulness of HRM in LPRD patients who do not response to PPI medication. Materials and Method : From July 2009 to July 2010, a total of 99 patients who were suspected LPRD according to symptoms (Reflux Symptom Index >13) and laryngoscopic findings (Reflux Finding Score >7) were retrospectively enrolled in this study. Patients were consisted of 31 men and 68 women, the mean age was 51.8 years, the mean BMI was 22.46. Patients have taken PPI medication for 2 months, after medication, they performed HRM. Comparative analysis was performed with results of the difference in symptoms. Results : In 99 patients, 37 patients (37.4%) show not improvement of LPRD symptoms after PPI medication. Among them, 18 patients (48.6%) showed abnormal findings that were classified as Peristaltic dysfunction (38.9%), Diffuse esophageal spasm (11.1%), Relaxation impairment of LES (11.1%), Achalasia (5.6%), Hypotensive LES (11.1%), Relaxation impairment of UES (11.1%), Nutcracker esophagus (5.6%), Decreased resting pressure (5.6%). Other 62 patients (62.6%) show improvement of LPRD symptoms, 23 patients (37.1%) showed abnormal findings. Most common finding was Peristaltic dysfunction (43.4%) More prevalent abnormal findings of HRM were found in patients who revealed no response to PPI medication (48.6% vs. 37.1%), but it does not reach the statistical significance. Conclusion : Although statistical significances is not showed, the difference observed in the frequency of HRM abnormal finding between response and no response for PPI medication. It has been estimated that HRM may be used to determine differential diagnosis in patients with LPRD. Further studies in lager population containing normal controls will be needed to prove clinical usefulness.

일부 스티렌 폭로 근로자의 뇨중 대사산물과 신경행동학적 검사

이창희,문덕환,이헌,박준한,김대환,이종태,전진호,김휘동,이채언,Lee, Chang-Hee,Moon, Deog-Hwan,Lee, Hun,Park, Jun-Han,Kim, Dae-Hwan,Lee, Jong-Tae,Chun, Jin-Ho,Kim, Hwi-Dong,Lee, Chae-Un 대한예방의학회 1996 Journal of Preventive Medicine and Public Health Vol.29 No.4

In order to prepare the fundamental data for the health promotion by assessing the exposure level of styrene, the author determined the concentration of mandelic acid and phenylglyoxylic acid in urine of 42 workers who were exposed to styrene by high performance liquid chromatography and surveyed 16 symptoms, by questionnaire and also tested neurobehavioral test(digit symbol, benton visual retention) in 2 FRP plants of Kyung Nam area from July to September, 1995. Control was sampled by age sex matching method. The concentration of styrene in air was determined by gas chromatography. The results were as follows; 1. Geometric mean concentration of styrene in air was 17.4ppm, geometric mean concentration of mandelic acid(MA) in urine were 404.3mg/g creatinine for exposure group, 46.4mg/g creatinine for control group, geometric mean concentration of phenylglyoxylic acid(PGA) in urine were 57.5mg/g creatinine for exposure group, 9.5mg/g creatinine for control group. Mean concentration of MA and PGA showed statistically significant difference between exposure group and control group(p<0.01). 2. Number of symptom were 2.9 for exposure group, 3.3 for control group, number of digit symbol were 24.1 for exposure group, 32.5 for control group, number of Benton visual retention test were 6.1 for exposure group, 6.0 for control group, respectively. As result of adjusting the education year, number of Benton visual retention test showed statistically significant difference between exposure group and control group(p<0.05). 3. Excellent correlation were observed between environmental styrene exposure and urinary MA(r=0.80), PGA(r=0.73), and MA+PGA(r=0.81).

초음파를 이용한 광학창 오염방지 모듈 개발

이창희,전기문,신재수,윤주영,조승현,강상우,Lee, ChangHee,Jeon, KiMun,Shin, JaeSoo,Yun, JuYoung,Cho, Seonghyun,Kang, Sang-Woo 한국진공학회 2013 Applied Science and Convergence Technology Vol.22 No.4

본 연구에서는 반도체 소자 생산 공정 중 발생하는 오염입자에 의해 실시간 오염입자 측정장치인 In-Situ Particle Monitor(ISPM)의 광학창의 오염을 방지하기 위한 모듈 개발에 관한 연구이다. 개발한 광학창 오염방지 모듈은 실시간으로 측정하는 ISPM 내 광학창 표면에 오염입자가 흡착되는 것을 방지하기 위한 장치로 적합한 초음파 모듈 개발이 성공적 연구의 핵심내용이다. 또한 그 효과를 극대화하기 위한 구조적인 최적화도 필요하지만 초음파 힘의 표면 전달효율 향상 기술도 개발이 필요한 핵심 기술이다. 개발된 광학창 오염방지 모듈이 장착된 ISPM은 양산용 증착공정 장비(BPSG 증착장비) 배기구에 설치되었으며, 공정조건 별 오염방지 모듈의 성능과 더불어 ISPM 측정 효율도 함께 검증하였다. We developed the contamination prevention module of an optical window for an In-Situ Particle Monitor (ISPM) system. the core part of the module is the generator of an ultrasonic wave and the module is to remove particles stuck to the window by the transfer of the wave force to the window surface. In order to enhance transfer efficiency of the waves the frequency of the ultrasonic wave was optimized and a low impedance material (plexiglass) and a soft sealing material (Si rubber) were used. The ISPM with the developed module was installed at the exhaust line of a BPSG CVD equipment and the effect of the module was verified.

AMOLED 디스플레이 기술 현황

이창희,Lee, Chang-Hui 한국광학회 2011 광학과 기술 Vol.15 No.4

확률적 조달기간을 갖는 연속조사 (Q,r) 재고모형

이창희,민계료,Lee Chang-Hui,Min Gye-Ryo 한국국방경영분석학회 1992 한국국방경영분석학회지 Vol.18 No.2

In this paper in order to prevent break of operation of equipments resulted from the delay of parts supply, the continuous review(Q, r) inventory model with probabilistic lead time is developed. If the lead tire is random varivable, the cycle also is stochastic. Then it is not easy to obtain the total cost equation of this inventory model. Therefore it is assumed that one cycle is the interval of reorder points. When the lead time is assumed to have exponential probability distribution, the lot-size and reorder point which minimize total cost are obtained. And as the lead time increases, the order quantity and the total cost are greater, but the reorder point increases by a certain point of time and then decreases.

영산강, 섬진강, 한강 하구역의 에머지 평가

이창희,강대석,Lee, Chang-Hee,Kang, Dae-Seok 해양환경안전학회 2008 海洋環境安全學會誌 Vol.14 No.2

에머지 개념을 이용하여 영산강하구역, 섬진강하구역, 한강하구역의 자연환경과 사회경제활동을 평가하고 하구역 관리와 관련한 시사점을 제시하였다. 영산강하구역, 섬진강하구역, 한강하구역의 자연환경과 사회경제활동에 대한 에머지 평가는 대형 하천이 유입하는 환경적 특성과 주변 지역의 사회경제활동 중심으로 기능하는 경제적 특성 등 이들 하구역의 특성을 잘 보여주었다. 각 하구역으로 유입하는 주요 자연환경 에머지는 하천, 조석, 강수 등 이었다. 그러나 이들 재생가능에머지가 세 하구역의 전체 에머지 유입량에서 차지하는 비율은 8% 미만으로 아주 적었다. 이에 비해 하구역의 외부에서 구입하여 지역경제에 투입하는 에머지의 비율은 $92{\sim}98%$로 대부분을 차지하였다. 단위면적당 에머지사용량, 인구수용력, 환경부하비율, 에머지지속성지수 등 다양한 에머지 지수가 현재 영산강하구역, 섬진강하구역, 한강하구역에서 이루어지고 있는 사회경제활동의 지속성이 아주 낮다는 것을 보여주었다. 영산강하구역, 섬진강하구역, 낙동강하구역의 자연환경이 우리 경제에 기여하는 가치는 $729{\sim}2,206$만 Em\/ha/yr으로 높게 평가되었다. 이는 우리나라 전체평균보다 2배 이상 높은 것인데, 하구역의 자연환경이 가지고 있는 생태경제적 중요성을 반영한다. 따라서 각 하구역이 가지고 있는 생태적 경제적 잠재력을 유지하고 회복하기 위한 하구환경관리정책의 수립 시행이 시급하다고 할 수 있다. 이는 인구 및 경제 집중의 완화, 하구의 환경수용력을 고려한 이용 개발 등 하구환경에 압력에 미치는 부정적 영향을 줄이기 위한 수요조절 측면의 정책과 훼손된 생태계의 복원, 인공생태계의 조성 등 생태계의 구조와기능을 회복하여 우리가 이용할 수 있는 생태계 서비스를 증가시키는 공급조절 측면의 두 가지 방향으로 추진할 필요가 있다. An emergy concept was used to evaluate the environment and economy of the estuarine areas of Yeongsan River, Seomjin River, and Han River in Korea. The emergy evaluations clearly showed ecological and socioeconomic characteristics of the estuarine areas that act as ecological and economic centers of surrounding areas. River, tide, and rain provided most of the renewable emergy inputs to the estuarine areas with their contribution to the total emergy input less than 8%. The estuarine areas mostly relied for their operation on the purchased emergy which accounted for $92{\sim}98%$ of the total emergy input to the systems. Emergy indices such as emergy use per unit area, population carrying capacity, environmental loading ratio, and emergy sustainability index revealed that the estuarine areas of Yeongsan River, Seomjin River, and Han River are not sustainable at the current level of economic activities in the areas. The ecological economic values of the environment of the areas were in the range of $7.29{\sim}22.06$ million Em\/ha/yr. They are more than twice that for the whole country, indicating the ecological and economic importance of the eatuarine areas. It is, therefore, urgent to establish and implement estuarine management policies to protect and restore the ecological and economic potentials of the estuarine areas of Yeongsan River, Seomjin River, and Han River. Management plans for the estuarine areas should include both demand-side measures such as reduction of population and economic concentration and consideration of ecological carrying capacity in planning stages for utilization and development of the areas, and supply-side ones such as restoration of degraded ecosystems and construction of new productive ecosystems.